Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels

Journal of Neuroscience

Volumn 25, Issue 13, 2005, Pages 3400-3413

  Winks, Joanna S ^a   Hughes, Simon ^b   Filippov, Alexander K ^b   Tatulian, Lucine ^b   Abogadie, Fe C ^b   Brown, David A ^b   Marsh, Stephen J ^b  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

G protein coupled receptors; M current; Neuronal excitability; PIP2; PLC; Sympathetic neurons

Indexed keywords

BRADYKININ; CALCIUM SENSING 1 PROTEIN; CALCIUM SENSING RECEPTOR; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; MUSCARINIC AGENT; MUSCARINIC RECEPTOR; OXOTREMORINE M; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHATIDYLINOSITOL KINASE; PHOSPHOLIPASE C; PLECKSTRIN; POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; FLUORESCENCE; GENE ACTIVATION; INTRACELLULAR TRANSPORT; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR3.1; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR3.2; MEMBRANE CURRENT; NERVE CELL M CHANNEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; RAT; RECEPTOR INTRINSIC ACTIVITY; SYMPATHETIC NERVE CELL; TIME;

ANIMALS; ANIMALS, NEWBORN; BRADYKININ; CALCIUM; CALCIUM-BINDING PROTEINS; CELL MEMBRANE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ELECTRIC STIMULATION; ESTRENES; FEMALE; FLUORESCENT DYES; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MALE; MICROSCOPY, CONFOCAL; MUSCARINIC AGONISTS; MUTATION; NEURAL INHIBITION; NEURONAL CALCIUM-SENSOR PROTEINS; NEURONS; NEUROPEPTIDES; OXOTREMORINE; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPASE C; PYRROLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC; SUPERIOR CERVICAL GANGLION; TRANSFECTION;

EID: 16344386958     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3231-04.2005     Document Type: Article

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