Regulation of KCNQ2/KCNQ3 current by G protein cycling: The kinetics of receptor-mediated signaling by Gq

Journal of General Physiology

Volumn 123, Issue 6, 2004, Pages 663-683

  Suh, Byung Chang ^a   Horowitz, Lisa F ^a,c   Hirdes, Wiebke ^a,b   Mackie, Ken ^a   Hille, Bertil ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c Fred Hutchinson Cancer Research Center   (United States)

Author keywords

M current; M1 muscarinic receptor; Magnesium; Phospholipase C; PIP2

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MAGNESIUM ION; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; OXOTREMORINE M; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL KCNQ3; POTASSIUM ION; PROTEIN SUBUNIT;

ARTICLE; CELL MEMBRANE; CHANNEL GATING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; KINETICS; MOUSE; NERVE EXCITABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; POTASSIUM TRANSPORT; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

CELL MEMBRANE; CLONING, MOLECULAR; COMPUTER SIMULATION; ELECTRIC CONDUCTIVITY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; ION CHANNEL GATING; KCNQ2 POTASSIUM CHANNEL; KCNQ3 POTASSIUM CHANNEL; KIDNEY; KINETICS; MAGNESIUM; MEMBRANE POTENTIALS; MODELS, BIOLOGICAL; POTASSIUM CHANNELS, VOLTAGE-GATED; RECEPTOR, MUSCARINIC M1; RECEPTORS, MUSCARINIC; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 2942672131     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200409029     Document Type: Article

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