메뉴 건너뛰기




Volumn 24, Issue 1, 2005, Pages 58-63

Potential future therapies for psoriasis

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; ALEFACEPT; BEVACIZUMAB; CHEMOKINE RECEPTOR ANTAGONIST; CNTO 1275; CYCLOSPORIN; CYCLOSPORIN A; CYTOKINE RECEPTOR ANTAGONIST; EFALIZUMAB; ETANERCEPT; FUMARIC ACID DERIVATIVE; FUMERIC ACID; GALIXIMAB; GLUCOCORTICOID; GOLIMUMAB; INFLIXIMAB; ISA 247; LENERCEPT; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY LM 609; ONERCEPT; PIMECROLIMUS; ROSIGLITAZONE; TAZAROTENE; UNCLASSIFIED DRUG;

EID: 15744364872     PISSN: 10855629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sder.2005.01.005     Document Type: Review
Times cited : (6)

References (82)
  • 1
    • 0036145337 scopus 로고    scopus 로고
    • The immunologic basis for the treatment of psoriasis with new biologic agents
    • J.G. Krueger The immunologic basis for the treatment of psoriasis with new biologic agents J Am Acad Dermatol 46 2002 1 23 quiz 23-6
    • (2002) J Am Acad Dermatol , vol.46 , pp. 1-23
    • Krueger, J.G.1
  • 3
    • 4544388284 scopus 로고    scopus 로고
    • Biological therapies in the systemic management of psoriasis: International Consensus Conference
    • W. Sterry Biological therapies in the systemic management of psoriasis International Consensus Conference Br J Dermatol 151 suppl 69 2004 3 17
    • (2004) Br J Dermatol , vol.151 , Issue.69 SUPPL. , pp. 3-17
    • Sterry, W.1
  • 4
    • 0036895587 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled phase III study evaluating efficacy and tolerability of 2 courses of alefacept in patients with chronic plaque psoriasis
    • G.G. Krueger A randomized, double-blind, placebo-controlled phase III study evaluating efficacy and tolerability of 2 courses of alefacept in patients with chronic plaque psoriasis J Am Acad Dermatol 47 2002 821 833
    • (2002) J Am Acad Dermatol , vol.47 , pp. 821-833
    • Krueger, G.G.1
  • 5
    • 17944381053 scopus 로고    scopus 로고
    • The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody
    • K. Papp The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody J Am Acad Dermatol 45 2001 665 674
    • (2001) J Am Acad Dermatol , vol.45 , pp. 665-674
    • Papp, K.1
  • 6
    • 6444222553 scopus 로고    scopus 로고
    • Etanercept in psoriasis
    • K.A. Papp Etanercept in psoriasis Expert Opin Pharmacother 5 2004 2139 2146
    • (2004) Expert Opin Pharmacother , vol.5 , pp. 2139-2146
    • Papp, K.A.1
  • 7
    • 0344876478 scopus 로고    scopus 로고
    • Appropriate and effective rheumatoid arthritis control: Role of TNF antagonists
    • E.C. Keystone Appropriate and effective rheumatoid arthritis control Role of TNF antagonists Drugs Today (Barc) 39 suppl B 2003 9 15
    • (2003) Drugs Today (Barc) , vol.39 , Issue.SUPPL. B , pp. 9-15
    • Keystone, E.C.1
  • 8
    • 1542369183 scopus 로고    scopus 로고
    • Optimizing anti-tumor necrosis factor strategies in inflammatory bowel disease
    • W.J. Sandborn Optimizing anti-tumor necrosis factor strategies in inflammatory bowel disease Curr Gastroenterol Rep 5 2003 501 505
    • (2003) Curr Gastroenterol Rep , vol.5 , pp. 501-505
    • Sandborn, W.J.1
  • 9
    • 18344382709 scopus 로고    scopus 로고
    • A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics
    • D.I. Spencer A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics Proteomics 2 2002 271 279
    • (2002) Proteomics , vol.2 , pp. 271-279
    • Spencer, D.I.1
  • 10
    • 0035406003 scopus 로고    scopus 로고
    • Successful treatment with a chimeric anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab) for a patient with relapsed mantle cell lymphoma who developed a human anti-chimeric antibody
    • T. Maeda Successful treatment with a chimeric anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab) for a patient with relapsed mantle cell lymphoma who developed a human anti-chimeric antibody Int J Hematol 74 2001 70 75
    • (2001) Int J Hematol , vol.74 , pp. 70-75
    • Maeda, T.1
  • 12
    • 0033125226 scopus 로고    scopus 로고
    • Antitumor necrosis factor therapy for inflammatory bowel disease: A review of agents, pharmacology, clinical results, and safety
    • W.J. Sandborn, S.B. Hanauer Antitumor necrosis factor therapy for inflammatory bowel disease A review of agents, pharmacology, clinical results, and safety Inflamm Bowel Dis 5 1999 119 133
    • (1999) Inflamm Bowel Dis , vol.5 , pp. 119-133
    • Sandborn, W.J.1    Hanauer, S.B.2
  • 13
    • 2442704195 scopus 로고    scopus 로고
    • Etanercept in rheumatoid arthritis patients with a poor therapeutic response to infliximab
    • R. Sanmarti [Etanercept in rheumatoid arthritis patients with a poor therapeutic response to infliximab] Med Clin (Barc) 122 2004 321 324
    • (2004) Med Clin (Barc) , vol.122 , pp. 321-324
    • Sanmarti, R.1
  • 14
    • 1442278507 scopus 로고    scopus 로고
    • Potential of tumor necrosis factor inhibitors in psoriasis and psoriatic arthritis
    • G. Krueger, K. Callis Potential of tumor necrosis factor inhibitors in psoriasis and psoriatic arthritis Arch Dermatol 140 2004 218 225
    • (2004) Arch Dermatol , vol.140 , pp. 218-225
    • Krueger, G.1    Callis, K.2
  • 15
    • 0042925466 scopus 로고    scopus 로고
    • Infliximab treatment of rheumatoid arthritis and Crohn's disease
    • I.K. Nahar Infliximab treatment of rheumatoid arthritis and Crohn's disease Ann Pharmacother 37 2003 1256 1265
    • (2003) Ann Pharmacother , vol.37 , pp. 1256-1265
    • Nahar, I.K.1
  • 16
    • 0042570265 scopus 로고    scopus 로고
    • Adalimumab (HUMIRA): A review
    • N. Scheinfeld Adalimumab (HUMIRA) A review J Drugs Dermatol 2 2003 375 377
    • (2003) J Drugs Dermatol , vol.2 , pp. 375-377
    • Scheinfeld, N.1
  • 18
    • 0036569910 scopus 로고    scopus 로고
    • TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection
    • D.R. Roach TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection J Immunol 168 2002 4620 4627
    • (2002) J Immunol , vol.168 , pp. 4620-4627
    • Roach, D.R.1
  • 19
    • 2442560241 scopus 로고    scopus 로고
    • Optimizing anti-TNF treatment in inflammatory bowel disease
    • P. Rutgeerts, G. Van Assche, S. Vermeire Optimizing anti-TNF treatment in inflammatory bowel disease Gastroenterology 126 2004 1593 1610
    • (2004) Gastroenterology , vol.126 , pp. 1593-1610
    • Rutgeerts, P.1    Van Assche, G.2    Vermeire, S.3
  • 20
    • 15744393717 scopus 로고    scopus 로고
    • The role of the cytoskeleton in cellular adhesion molecule expression in tumor necrosis factor-stimulated endothelial cells
    • E. VandenBerg The role of the cytoskeleton in cellular adhesion molecule expression in tumor necrosis factor-stimulated endothelial cells J Cell Biochem 91 2004 926 937
    • (2004) J Cell Biochem , vol.91 , pp. 926-937
    • Vandenberg, E.1
  • 21
    • 0035523923 scopus 로고    scopus 로고
    • Down-regulation of cell adhesion molecules LFA-1 and ICAM-1 after in vitro treatment with the anti-TNF-alpha agent thalidomide
    • B. Settles Down-regulation of cell adhesion molecules LFA-1 and ICAM-1 after in vitro treatment with the anti-TNF-alpha agent thalidomide Cell Mol Biol (Noisy-le-grand) 47 2001 1105 1114
    • (2001) Cell Mol Biol (Noisy-le-grand) , vol.47 , pp. 1105-1114
    • Settles, B.1
  • 22
    • 0036090346 scopus 로고    scopus 로고
    • Control of leukocyte rolling velocity in TNF-alpha-induced inflammation by LFA-1 and Mac-1
    • J.L. Dunne Control of leukocyte rolling velocity in TNF-alpha-induced inflammation by LFA-1 and Mac-1 Blood 99 2002 336 341
    • (2002) Blood , vol.99 , pp. 336-341
    • Dunne, J.L.1
  • 23
    • 0041653315 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: A multicenter active-surveillance report
    • J.J. Gomez-Reino Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk A multicenter active-surveillance report Arthritis Rheum 48 2003 2122 2127
    • (2003) Arthritis Rheum , vol.48 , pp. 2122-2127
    • Gomez-Reino, J.J.1
  • 24
    • 0036098867 scopus 로고    scopus 로고
    • A critical assessment of new therapies in inflammatory bowel disease
    • P. Rutgeerts A critical assessment of new therapies in inflammatory bowel disease J Gastroenterol Hepatol 17 suppl 2002 S176 S185
    • (2002) J Gastroenterol Hepatol , vol.17 , Issue.SUPPL.
    • Rutgeerts, P.1
  • 25
    • 0036022681 scopus 로고    scopus 로고
    • Therapeutic approaches in multiple sclerosis: Lessons from failed and interrupted treatment trials
    • H. Wiendl, R. Hohlfeld Therapeutic approaches in multiple sclerosis lessons from failed and interrupted treatment trials BioDrugs 16 2002 183 200
    • (2002) BioDrugs , vol.16 , pp. 183-200
    • Wiendl, H.1    Hohlfeld, R.2
  • 26
    • 0033546665 scopus 로고    scopus 로고
    • TNF neutralization in MS: Results of a randomized, placebo-controlled multicenter study
    • The Lenercept Multiple Sclerosis Study Group The University of British Columbia MS/MRI Analysis Group
    • The Lenercept Multiple Sclerosis Study Group The University of British Columbia MS/MRI Analysis Group TNF neutralization in MS results of a randomized, placebo-controlled multicenter study Neurology 53 1999 457 465
    • (1999) Neurology , vol.53 , pp. 457-465
  • 28
    • 4644327125 scopus 로고    scopus 로고
    • Infliximab induction therapy for patients with severe plaque-type psoriasis: A randomized, double-blind, placebo-controlled trial
    • A.B. Gottlieb Infliximab induction therapy for patients with severe plaque-type psoriasis a randomized, double-blind, placebo-controlled trial J Am Acad Dermatol 51 2004 534 542
    • (2004) J Am Acad Dermatol , vol.51 , pp. 534-542
    • Gottlieb, A.B.1
  • 29
    • 0035832515 scopus 로고    scopus 로고
    • Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: A randomised trial
    • U. Chaudhari Efficacy and safety of infliximab monotherapy for plaque-type psoriasis A randomised trial Lancet 357 2001 1842 1847
    • (2001) Lancet , vol.357 , pp. 1842-1847
    • Chaudhari, U.1
  • 31
    • 0034808009 scopus 로고    scopus 로고
    • Safety, pharmacokinetics and pharmacodynamics of recombinant human tumour necrosis factor-binding protein-1 (Onercept) injected by intravenous, intramuscular and subcutaneous routes into healthy volunteers
    • I. Trinchard-Lugan Safety, pharmacokinetics and pharmacodynamics of recombinant human tumour necrosis factor-binding protein-1 (Onercept) injected by intravenous, intramuscular and subcutaneous routes into healthy volunteers Eur Cytokine Netw 12 2001 391 398
    • (2001) Eur Cytokine Netw , vol.12 , pp. 391-398
    • Trinchard-Lugan, I.1
  • 32
    • 0032773289 scopus 로고    scopus 로고
    • IL-12 as a therapeutic target for pharmacological modulation in immune-mediated and inflammatory diseases: Regulation of T helper 1/T helper 2 responses
    • G. Hasko, C. Szabo IL-12 as a therapeutic target for pharmacological modulation in immune-mediated and inflammatory diseases Regulation of T helper 1/T helper 2 responses Br J Pharmacol 127 1999 1295 1304
    • (1999) Br J Pharmacol , vol.127 , pp. 1295-1304
    • Hasko, G.1    Szabo, C.2
  • 33
    • 9744265704 scopus 로고    scopus 로고
    • A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis
    • C.L. Kauffman A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis J Invest Dermatol 123 2004 1037 1044
    • (2004) J Invest Dermatol , vol.123 , pp. 1037-1044
    • Kauffman, C.L.1
  • 34
    • 1842735276 scopus 로고    scopus 로고
    • Evaluation of safety and clinical activity of multiple doses of the anti-CD80 monoclonal antibody, galiximab, in patients with moderate to severe plaque psoriasis
    • A.B. Gottlieb Evaluation of safety and clinical activity of multiple doses of the anti-CD80 monoclonal antibody, galiximab, in patients with moderate to severe plaque psoriasis Clin Immunol 111 2004 28 37
    • (2004) Clin Immunol , vol.111 , pp. 28-37
    • Gottlieb, A.B.1
  • 35
    • 0043127027 scopus 로고    scopus 로고
    • Efalizumab: An overview
    • C.L. Leonardi Efalizumab An overview J Am Acad Dermatol 49 suppl 2003 S98 S104
    • (2003) J Am Acad Dermatol , vol.49 , Issue.SUPPL.
    • Leonardi, C.L.1
  • 36
    • 0042343801 scopus 로고    scopus 로고
    • A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
    • J.C. Yang A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer N Engl J Med 349 2003 427 434
    • (2003) N Engl J Med , vol.349 , pp. 427-434
    • Yang, J.C.1
  • 37
    • 0032568558 scopus 로고    scopus 로고
    • Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb
    • H. Wu Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb Proc Natl Acad Sci USA 95 1998 6037 6042
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6037-6042
    • Wu, H.1
  • 38
    • 3042845754 scopus 로고    scopus 로고
    • Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities
    • B.J. Nickoloff, F.O. Nestle Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities J Clin Invest 113 2004 1664 1675
    • (2004) J Clin Invest , vol.113 , pp. 1664-1675
    • Nickoloff, B.J.1    Nestle, F.O.2
  • 40
    • 4944226966 scopus 로고    scopus 로고
    • Safety issues related to emerging therapies for rheumatoid arthritis
    • E.C. Keystone Safety issues related to emerging therapies for rheumatoid arthritis Clin Exp Rheumatol 22 suppl 2004 S148 S150
    • (2004) Clin Exp Rheumatol , vol.22 , Issue.SUPPL.
    • Keystone, E.C.1
  • 41
    • 3142619217 scopus 로고    scopus 로고
    • Ciclosporin in psoriasis clinical practice: An international consensus statement
    • C.E. Griffiths Ciclosporin in psoriasis clinical practice An international consensus statement Br J Dermatol 150 suppl 67 2004 11 23
    • (2004) Br J Dermatol , vol.150 , Issue.67 SUPPL. , pp. 11-23
    • Griffiths, C.E.1
  • 42
    • 3342914815 scopus 로고    scopus 로고
    • ISAtx-247 (Isotechnika/Roche)
    • F.J. Dumont ISAtx-247 (Isotechnika/Roche) Curr Opin Invest Drugs 5 2004 542 550
    • (2004) Curr Opin Invest Drugs , vol.5 , pp. 542-550
    • Dumont, F.J.1
  • 43
    • 15744365974 scopus 로고    scopus 로고
    • FC06.9: A randomized, multicenter, double-blind, placebo-controlled phase 2 trial of ISA247 in patients with chronic plaque psoriasis
    • Nov 2004 Florence. Florence, Italy
    • Bissonnette R, et al. FC06.9: A randomized, multicenter, double-blind, placebo-controlled phase 2 trial of ISA247 in patients with chronic plaque psoriasis, in EADV 13th Congress, Nov 2004 Florence. 2004: Florence, Italy
    • (2004) EADV 13th Congress
    • Bissonnette, R.1
  • 44
    • 4344625851 scopus 로고    scopus 로고
    • Current concepts and review of pimecrolimus in the treatment of psoriasis
    • Wolff, K,, et al. Current concepts and review of pimecrolimus in the treatment of psoriasis. Dermatol Clin 22461-465, ix-x, 2004
    • (2004) Dermatol Clin , pp. 22461-22465
    • Wolff, K.1
  • 45
    • 0035211722 scopus 로고    scopus 로고
    • Pimecrolimus (Elidel, SDZ ASM 981)--preclinical pharmacologic profile and skin selectivity
    • A. Stuetz, M. Grassberger, J.G. Meingassner Pimecrolimus (Elidel, SDZ ASM 981)--preclinical pharmacologic profile and skin selectivity Semin Cutan Med Surg 20 2001 233 241
    • (2001) Semin Cutan Med Surg , vol.20 , pp. 233-241
    • Stuetz, A.1    Grassberger, M.2    Meingassner, J.G.3
  • 46
    • 19244366008 scopus 로고    scopus 로고
    • Pimecrolimus identifies a common genomic anti-inflammatory profile, is clinically highly effective in psoriasis and is well tolerated
    • K. Rappersberger Pimecrolimus identifies a common genomic anti-inflammatory profile, is clinically highly effective in psoriasis and is well tolerated J Invest Dermatol 119 2002 876 887
    • (2002) J Invest Dermatol , vol.119 , pp. 876-887
    • Rappersberger, K.1
  • 47
    • 0042413498 scopus 로고    scopus 로고
    • Long-term safety aspects of systemic therapy with fumaric acid esters in severe psoriasis
    • J.J. Hoefnagel Long-term safety aspects of systemic therapy with fumaric acid esters in severe psoriasis Br J Dermatol 149 2003 363 369
    • (2003) Br J Dermatol , vol.149 , pp. 363-369
    • Hoefnagel, J.J.1
  • 48
    • 1642329197 scopus 로고    scopus 로고
    • Monomethylfumarate affects polarization of monocyte-derived dendritic cells resulting in down-regulated Th1 lymphocyte responses
    • N.H. Litjens Monomethylfumarate affects polarization of monocyte-derived dendritic cells resulting in down-regulated Th1 lymphocyte responses Eur J Immunol 34 2004 565 575
    • (2004) Eur J Immunol , vol.34 , pp. 565-575
    • Litjens, N.H.1
  • 49
    • 0345732760 scopus 로고    scopus 로고
    • Dimethylfumarate is a potent inducer of apoptosis in human T cells
    • F. Treumer Dimethylfumarate is a potent inducer of apoptosis in human T cells J Invest Dermatol 121 2003 1383 1388
    • (2003) J Invest Dermatol , vol.121 , pp. 1383-1388
    • Treumer, F.1
  • 50
    • 0036569398 scopus 로고    scopus 로고
    • Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells
    • R. Loewe Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells J Immunol 168 2002 4781 4787
    • (2002) J Immunol , vol.168 , pp. 4781-4787
    • Loewe, R.1
  • 51
    • 0033757235 scopus 로고    scopus 로고
    • The treatment of psoriasis with etretinate and acitretin: A follow up of actual use
    • N.L. Magis The treatment of psoriasis with etretinate and acitretin a follow up of actual use Eur J Dermatol 10 2002 517 521
    • (2002) Eur J Dermatol , vol.10 , pp. 517-521
    • Magis, N.L.1
  • 52
    • 4644363465 scopus 로고    scopus 로고
    • A retinoid X receptor (RXR)-selective retinoid reveals that RXR-alpha is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands
    • D.L. Crowe, R.A. Chandraratna A retinoid X receptor (RXR)-selective retinoid reveals that RXR-alpha is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands Breast Cancer Res 6 2004 R546 R555
    • (2004) Breast Cancer Res , vol.6
    • Crowe, D.L.1    Chandraratna, R.A.2
  • 53
    • 4644297829 scopus 로고    scopus 로고
    • Systemic treatment of psoriatic patients with bexarotene decreases epidermal proliferation and parameters for inflammation, and improves differentiation in lesional skin
    • J.V. Smit Systemic treatment of psoriatic patients with bexarotene decreases epidermal proliferation and parameters for inflammation, and improves differentiation in lesional skin J Am Acad Dermatol 51 2004 257 264
    • (2004) J Am Acad Dermatol , vol.51 , pp. 257-264
    • Smit, J.V.1
  • 54
    • 3242669722 scopus 로고    scopus 로고
    • Differential effects of 9-cis retinoic acid on expression of CC chemokine receptors in human monocytes
    • I.S. Kim Differential effects of 9-cis retinoic acid on expression of CC chemokine receptors in human monocytes Biochem Pharmacol 68 2004 611 620
    • (2004) Biochem Pharmacol , vol.68 , pp. 611-620
    • Kim, I.S.1
  • 55
    • 0142123179 scopus 로고    scopus 로고
    • Retinoic acid receptor-mediated induction of ABCA1 in macrophages
    • P. Costet Retinoic acid receptor-mediated induction of ABCA1 in macrophages Mol Cell Biol 23 2003 7756 7766
    • (2003) Mol Cell Biol , vol.23 , pp. 7756-7766
    • Costet, P.1
  • 56
    • 0041522463 scopus 로고    scopus 로고
    • Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptors
    • M. Iwata, Y. Eshima, H. Kagechika Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptors Int Immunol 15 2003 1017 1025
    • (2003) Int Immunol , vol.15 , pp. 1017-1025
    • Iwata, M.1    Eshima, Y.2    Kagechika, H.3
  • 57
    • 0037303259 scopus 로고    scopus 로고
    • Retinoic acid metabolism and mechanism of action: A review
    • J. Marill Retinoic acid metabolism and mechanism of action A review Curr Drug Metab 4 2003 1 10
    • (2003) Curr Drug Metab , vol.4 , pp. 1-10
    • Marill, J.1
  • 58
    • 0040958788 scopus 로고    scopus 로고
    • Retinoids inhibit interleukin-12 production in macrophages through physical associations of retinoid X receptor and NFkappaB
    • S.Y. Na Retinoids inhibit interleukin-12 production in macrophages through physical associations of retinoid X receptor and NFkappaB J Biol Chem 274 1999 7674 7680
    • (1999) J Biol Chem , vol.274 , pp. 7674-7680
    • Na, S.Y.1
  • 60
    • 0032697030 scopus 로고    scopus 로고
    • Clinical pharmacokinetics and drug metabolism of tazarotene: A novel topical treatment for acne and psoriasis
    • D.D. Tang-Liu, R.M. Matsumoto, J.I. Usansky Clinical pharmacokinetics and drug metabolism of tazarotene A novel topical treatment for acne and psoriasis Clin Pharmacokinet 37 1999 273 287
    • (1999) Clin Pharmacokinet , vol.37 , pp. 273-287
    • Tang-Liu, D.D.1    Matsumoto, R.M.2    Usansky, J.I.3
  • 61
    • 0347357686 scopus 로고    scopus 로고
    • Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation
    • S. Cuzzocrea Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation Eur J Pharmacol 483 2004 79 93
    • (2004) Eur J Pharmacol , vol.483 , pp. 79-93
    • Cuzzocrea, S.1
  • 62
    • 10644278955 scopus 로고    scopus 로고
    • Discovery of cytokine mimics using cell-based systems
    • S.G. Miller Discovery of cytokine mimics using cell-based systems Drug Discov Today 5 12 suppl 1 2000 77 83
    • (2000) Drug Discov Today , vol.5 , Issue.12 SUPPL. 1 , pp. 77-83
    • Miller, S.G.1
  • 63
    • 0033117570 scopus 로고    scopus 로고
    • Small molecule cytokine mimetics
    • A. Whitty, C.W. Borysenko Small molecule cytokine mimetics Chem Biol 6 1999 R107 R118
    • (1999) Chem Biol , vol.6
    • Whitty, A.1    Borysenko, C.W.2
  • 65
    • 0034092634 scopus 로고    scopus 로고
    • International union of pharmacology. XXII. Nomenclature for chemokine receptors
    • P.M. Murphy International union of pharmacology. XXII. Nomenclature for chemokine receptors Pharmacol Rev 52 2000 145 176
    • (2000) Pharmacol Rev , vol.52 , pp. 145-176
    • Murphy, P.M.1
  • 66
    • 0034043105 scopus 로고    scopus 로고
    • C-C and C-X-C chemokines trigger firm adhesion of monocytes to vascular endothelium under flow conditions
    • F.W. Luscinskas C-C and C-X-C chemokines trigger firm adhesion of monocytes to vascular endothelium under flow conditions Ann N Y Acad Sci 902 2000 288 293
    • (2000) Ann N Y Acad Sci , vol.902 , pp. 288-293
    • Luscinskas, F.W.1
  • 67
    • 11844305963 scopus 로고    scopus 로고
    • Attenuation of murine collagen-induced arthritis by a novel, potent and selective small molecule inhibitor of I{kappa}B kinase 2, TPCA-1, occurs via reduction of proinflammatory cytokines and antigen-induced T cell proliferation
    • P.L. Podolin, J.F. Callahan, B.J. Bolognese Attenuation of murine collagen-induced arthritis by a novel, potent and selective small molecule inhibitor of I{kappa}B kinase 2, TPCA-1, occurs via reduction of proinflammatory cytokines and antigen-induced T cell proliferation J Pharmacol Exp Ther 312 2005 373 381
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 373-381
    • Podolin, P.L.1    Callahan, J.F.2    Bolognese, B.J.3
  • 68
    • 0037452709 scopus 로고    scopus 로고
    • Binding of small molecules to an adaptive protein-protein interface
    • M.R. Arkin Binding of small molecules to an adaptive protein-protein interface Proc Natl Acad Sci USA 100 2003 1603 1608
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1603-1608
    • Arkin, M.R.1
  • 69
    • 0036785514 scopus 로고    scopus 로고
    • Biological activity of a novel nonpeptide antagonist to the interleukin-6 receptor 20S,21-epoxy-resibufogenin-3-formate
    • M. Hayashi Biological activity of a novel nonpeptide antagonist to the interleukin-6 receptor 20S,21-epoxy-resibufogenin-3-formate J Pharmacol Exp Ther 303 2002 104 109
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 104-109
    • Hayashi, M.1
  • 70
    • 0038802739 scopus 로고    scopus 로고
    • Discovery of small molecule leads in a biotechnology datastream
    • T.R. Gadek, R.S. McDowell Discovery of small molecule leads in a biotechnology datastream Drug Discov Today 8 2003 545 550
    • (2003) Drug Discov Today , vol.8 , pp. 545-550
    • Gadek, T.R.1    McDowell, R.S.2
  • 71
    • 0037212039 scopus 로고    scopus 로고
    • Small molecule antagonists of proteins
    • T.R. Gadek, J.B. Nicholas Small molecule antagonists of proteins Biochem Pharmacol 65 2003 1 8
    • (2003) Biochem Pharmacol , vol.65 , pp. 1-8
    • Gadek, T.R.1    Nicholas, J.B.2
  • 72
    • 18244370299 scopus 로고    scopus 로고
    • Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule
    • T.R. Gadek Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule Science 295 2002 1086 1089
    • (2002) Science , vol.295 , pp. 1086-1089
    • Gadek, T.R.1
  • 73
    • 0033571626 scopus 로고    scopus 로고
    • Cutting edge: A small molecule antagonist of LFA-1-mediated cell adhesion
    • T.A. Kelly Cutting edge A small molecule antagonist of LFA-1-mediated cell adhesion J Immunol 163 1999 5173 5177
    • (1999) J Immunol , vol.163 , pp. 5173-5177
    • Kelly, T.A.1
  • 74
    • 0036035393 scopus 로고    scopus 로고
    • Molluscum contagiosum: Recent advances in pathogenic mechanisms, and new therapies
    • K.J. Smith, H. Skelton Molluscum contagiosum recent advances in pathogenic mechanisms, and new therapies Am J Clin Dermatol 3 2002 535 545
    • (2002) Am J Clin Dermatol , vol.3 , pp. 535-545
    • Smith, K.J.1    Skelton, H.2
  • 75
    • 0035060692 scopus 로고    scopus 로고
    • The herpesvirus 8-encoded chemokine vMIP-II, but not the poxvirus-encoded chemokine MC148, inhibits the CCR10 receptor
    • H.R. Luttichau The herpesvirus 8-encoded chemokine vMIP-II, but not the poxvirus-encoded chemokine MC148, inhibits the CCR10 receptor Eur J Immunol 31 2001 1217 1220
    • (2001) Eur J Immunol , vol.31 , pp. 1217-1220
    • Luttichau, H.R.1
  • 76
    • 0036409394 scopus 로고    scopus 로고
    • Myxoma virus immunomodulatory protein M156R is a structural mimic of eukaryotic translation initiation factor eIF2alpha
    • T.A. Ramelot Myxoma virus immunomodulatory protein M156R is a structural mimic of eukaryotic translation initiation factor eIF2alpha J Mol Biol 322 2002 943 954
    • (2002) J Mol Biol , vol.322 , pp. 943-954
    • Ramelot, T.A.1
  • 77
    • 0030249374 scopus 로고    scopus 로고
    • Soluble interferon-gamma receptors encoded by poxviruses
    • A. Alcami, G.L. Smith Soluble interferon-gamma receptors encoded by poxviruses Comp Immunol Microbiol Infect Dis 19 1996 305 317
    • (1996) Comp Immunol Microbiol Infect Dis , vol.19 , pp. 305-317
    • Alcami, A.1    Smith, G.L.2
  • 78
    • 0029015072 scopus 로고
    • Species specificity of ectromelia virus and vaccinia virus interferon-gamma binding proteins
    • K. Mossman Species specificity of ectromelia virus and vaccinia virus interferon-gamma binding proteins Virology 208 1995 762 769
    • (1995) Virology , vol.208 , pp. 762-769
    • Mossman, K.1
  • 79
    • 15744380263 scopus 로고    scopus 로고
    • Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition
    • J.F. Ohren Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition Nat Struct Mol Biol 11 2004 1192 1197
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 1192-1197
    • Ohren, J.F.1
  • 80
    • 3342918498 scopus 로고    scopus 로고
    • The p38 MAP kinase pathway as a therapeutic target in inflammatory disease
    • J. Saklatvala The p38 MAP kinase pathway as a therapeutic target in inflammatory disease Curr Opin Pharmacol 4 2004 372 377
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 372-377
    • Saklatvala, J.1
  • 81
    • 2942530310 scopus 로고    scopus 로고
    • ERK and p38 MAPK-activated protein kinases: A family of protein kinases with diverse biological functions
    • P.P. Roux, J. Blenis ERK and p38 MAPK-activated protein kinases A family of protein kinases with diverse biological functions Microbiol Mol Biol Rev 68 2004 320 344
    • (2004) Microbiol Mol Biol Rev , vol.68 , pp. 320-344
    • Roux, P.P.1    Blenis, J.2
  • 82
    • 5344273921 scopus 로고    scopus 로고
    • A novel series of p38 MAP kinase inhibitors for the potential treatment of rheumatoid arthritis
    • D.S. Brown A novel series of p38 MAP kinase inhibitors for the potential treatment of rheumatoid arthritis Bioorg Med Chem Lett 14 2004 5383 5387
    • (2004) Bioorg Med Chem Lett , vol.14 , pp. 5383-5387
    • Brown, D.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.