메뉴 건너뛰기




Volumn 6, Issue 4, 1999, Pages

Small molecule cytokine mimetics

Author keywords

[No Author keywords available]

Indexed keywords


EID: 0033117570     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(99)80034-9     Document Type: Review
Times cited : (38)

References (42)
  • 1
    • 0025162844 scopus 로고
    • Structural design and molecular evolution of a cytokine receptor superfamily
    • Bazan, J.F. (1990). Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl Acad. Sci. USA 87, 6934-6938.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 6934-6938
    • Bazan, J.F.1
  • 3
    • 9444236174 scopus 로고    scopus 로고
    • Small peptides as potent mimetics of the protein hormone erythropoietin
    • Wrighton, N.C., et al., & Dower, W.J. (1996). Small peptides as potent mimetics of the protein hormone erythropoietin. Science 273, 458-463.
    • (1996) Science , vol.273 , pp. 458-463
    • Wrighton, N.C.1    Dower, W.J.2
  • 4
    • 0030773876 scopus 로고    scopus 로고
    • Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine
    • Cwirla, S.E., et al., & Dower, W.J. (1997). Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine. Science 276, 1696-1699.
    • (1997) Science , vol.276 , pp. 1696-1699
    • Cwirla, S.E.1    Dower, W.J.2
  • 6
    • 0032504007 scopus 로고    scopus 로고
    • A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor
    • Tian, S.-S., et al., & Rosen, J. (1998). A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor. Science 281, 257-259.
    • (1998) Science , vol.281 , pp. 257-259
    • Tian, S.-S.1    Rosen, J.2
  • 7
    • 0032577533 scopus 로고    scopus 로고
    • A non-peptide compound which can mimic the effect of thrombopoietin via c-Mpl
    • Kimura, T., Kaburaki, H., Tsujino, T., Ikeda, Y., Kato, H. & Watanabe, Y. (1998). A non-peptide compound which can mimic the effect of thrombopoietin via c-Mpl. FEBS Lett. 428, 250-254.
    • (1998) FEBS Lett. , vol.428 , pp. 250-254
    • Kimura, T.1    Kaburaki, H.2    Tsujino, T.3    Ikeda, Y.4    Kato, H.5    Watanabe, Y.6
  • 8
    • 0025343230 scopus 로고
    • Signal transduction by receptors with tyrosine kinase activity
    • Ullrich, A. & Schlessinger, J. (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 9
    • 0028260226 scopus 로고
    • Structural and functional basis for hormone binding and receptor oligomerization
    • Wells, J.A. (1994). Structural and functional basis for hormone binding and receptor oligomerization. Curr. Opin. Cell Biol. 6, 163-173.
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 163-173
    • Wells, J.A.1
  • 10
    • 0027328343 scopus 로고
    • The alphas, betas, and kinases of cytokine receptor complexes
    • Stahl, N. & Yancopoulos, G.D. (1993). The alphas, betas, and kinases of cytokine receptor complexes. Cell 74, 587-590.
    • (1993) Cell , vol.74 , pp. 587-590
    • Stahl, N.1    Yancopoulos, G.D.2
  • 11
    • 0029982521 scopus 로고    scopus 로고
    • Hematopoietic receptor complexes
    • Wells, J.A. & de Vos, A.M. (1996). Hematopoietic receptor complexes. Annu. Rev. Biochem. 65, 609-634.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 609-634
    • Wells, J.A.1    de Vos, A.M.2
  • 12
    • 0026764441 scopus 로고
    • Rational design of potent antagonists to the human growth hormone receptor
    • Fuh, G., Cunningham, B.C., Fukunaga, R., Nagata, S., Goeddel, D.V. & Wells, J.A. (1992). Rational design of potent antagonists to the human growth hormone receptor. Science 256, 1677-1680.
    • (1992) Science , vol.256 , pp. 1677-1680
    • Fuh, G.1    Cunningham, B.C.2    Fukunaga, R.3    Nagata, S.4    Goeddel, D.V.5    Wells, J.A.6
  • 14
    • 0031033923 scopus 로고    scopus 로고
    • Homodimerization of erythropoietin receptor by a bivalent monoclonal antibody triggers cell proliferation and differentiation of erythroid precursors
    • Schneider, H., et al., & Giebel, L.B. (1997). Homodimerization of erythropoietin receptor by a bivalent monoclonal antibody triggers cell proliferation and differentiation of erythroid precursors. Blood 89, 473-482.
    • (1997) Blood , vol.89 , pp. 473-482
    • Schneider, H.1    Giebel, L.B.2
  • 15
    • 0031008572 scopus 로고    scopus 로고
    • Characterization of the receptor binding determinants of granulocyte colony stimulating factor
    • Young, D.C., Zhan, H., Cheng, Q.L, Hou, L. & Matthews, D.J. (1997). Characterization of the receptor binding determinants of granulocyte colony stimulating factor. Protein Sci. 6, 1228-1236.
    • (1997) Protein Sci. , vol.6 , pp. 1228-1236
    • Young, D.C.1    Zhan, H.2    Cheng, Q.L.3    Hou, L.4    Matthews, D.J.5
  • 16
    • 0028832719 scopus 로고
    • Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity
    • Alexander, W.S., Metcalf, D. & Dunn, A.R. (1995). Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity. EMBO J. 14, 5569-5578.
    • (1995) EMBO J. , vol.14 , pp. 5569-5578
    • Alexander, W.S.1    Metcalf, D.2    Dunn, A.R.3
  • 17
    • 0032052221 scopus 로고    scopus 로고
    • Surrogate thrombopoietin
    • Abe, M., et al. & Masuho, Y. (1998). Surrogate thrombopoietin. Immunol. Lett. 61, 73-78.
    • (1998) Immunol. Lett. , vol.61 , pp. 73-78
    • Abe, M.1    Masuho, Y.2
  • 18
    • 3543123430 scopus 로고    scopus 로고
    • An agonist murine monoclonal antibody to the human c-Mpl receptor stimulates megakaryocytopoiesis
    • Deng, B. et al., & Avraham, H. (1998). An agonist murine monoclonal antibody to the human c-Mpl receptor stimulates megakaryocytopoiesis. Blood 92, 1981-1988.
    • (1998) Blood , vol.92 , pp. 1981-1988
    • Deng, B.1    Avraham, H.2
  • 19
    • 0032540358 scopus 로고    scopus 로고
    • Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity
    • Clackson, T., Ultsch, M.H., Wells, J.A. & de Vos, A.M. (1998). Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J. Mol. Biol. 277, 1111-1128.
    • (1998) J. Mol. Biol. , vol.277 , pp. 1111-1128
    • Clackson, T.1    Ultsch, M.H.2    Wells, J.A.3    de Vos, A.M.4
  • 20
    • 0032570710 scopus 로고    scopus 로고
    • Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies
    • Rowlinson, S.W., et al., & Waters, M.J. (1998). Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies. J. Biol. Chem. 273, 5307-5314.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5307-5314
    • Rowlinson, S.W.1    Waters, M.J.2
  • 21
    • 0032188942 scopus 로고    scopus 로고
    • Efficiency of signalling through cytokine receptors depends critically on receptor orientation
    • Syed, R.S., et al., & Stroud, R.M. (1998). Efficiency of signalling through cytokine receptors depends critically on receptor orientation. Nature 395, 511-516.
    • (1998) Nature , vol.395 , pp. 511-516
    • Syed, R.S.1    Stroud, R.M.2
  • 23
    • 0026089503 scopus 로고
    • Erythropoietin receptors induced by dimethyl sulfoxide exhibit positive cooperativity associated with an amplified biologic response
    • Yonekura, S., Chern, Y., Donahue, K.A., Feldman, L, Vanasse, G.J. & Sytkowski, A.J. (1991). Erythropoietin receptors induced by dimethyl sulfoxide exhibit positive cooperativity associated with an amplified biologic response. Proc. Natl Acad. Sci. USA 88, 2535-2539.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 2535-2539
    • Yonekura, S.1    Chern, Y.2    Donahue, K.A.3    Feldman, L.4    Vanasse, G.J.5    Sytkowski, A.J.6
  • 24
    • 0025870016 scopus 로고
    • Comparison of the effects of hypertonic sucrose and intracellular potassium depletion on growth hormone receptor binding kinetics and down-regulation in IM-9 cells: Evidence for a sequential block of receptor-mediated endocytosis
    • Ilondo, M.M, Smal, J., de Meyts, P. & Courtoy, P.J. (1991). Comparison of the effects of hypertonic sucrose and intracellular potassium depletion on growth hormone receptor binding kinetics and down-regulation in IM-9 cells: Evidence for a sequential block of receptor-mediated endocytosis. Endocrinology 128, 1597-1602.
    • (1991) Endocrinology , vol.128 , pp. 1597-1602
    • Ilondo, M.M.1    Smal, J.2    de Meyts, P.3    Courtoy, P.J.4
  • 25
    • 0344573809 scopus 로고    scopus 로고
    • Growth hormone binding affinity for its receptor surpasses the requirements for cellular activity
    • Pearce, K.H. Jr., Cunningham, B.C., Fuh, G., Teeri, G. & Wells, J.A. (1999). Growth hormone binding affinity for its receptor surpasses the requirements for cellular activity. Biochemistry 38, 81 -89.
    • (1999) Biochemistry , vol.38 , pp. 81-89
    • Pearce K.H., Jr.1    Cunningham, B.C.2    Fuh, G.3    Teeri, G.4    Wells, J.A.5
  • 26
    • 0027451432 scopus 로고
    • Two distinct functional sites of human interleukin 4 are identified by variants impaired in either receptor binding or receptor activation
    • Kruse, N., Shen, B.-J., Arnold, S., Tony, H.-P., Muller, T. & Sebald, W. (1993). Two distinct functional sites of human interleukin 4 are identified by variants impaired in either receptor binding or receptor activation. EMBO J. 12, 5121-5129.
    • (1993) EMBO J. , vol.12 , pp. 5121-5129
    • Kruse, N.1    Shen, B.-J.2    Arnold, S.3    Tony, H.-P.4    Muller, T.5    Sebald, W.6
  • 27
    • 0032573092 scopus 로고    scopus 로고
    • Interaction affinity between cytokine receptor components on the cell surface
    • Whitty, A., et al., & Burkly, L.C. (1998). Interaction affinity between cytokine receptor components on the cell surface. Proc. Natl Acad. Sci. USA 95, 13165-13170.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 13165-13170
    • Whitty, A.1    Burkly, L.C.2
  • 28
    • 0028286627 scopus 로고
    • Heterodimerization of the IL-2 receptor β- and γ-chain cytoplasmic domians is required for signalling
    • Nakamura, Y., et al., & Leonard, W.J. (1994.) Heterodimerization of the IL-2 receptor β- and γ-chain cytoplasmic domians is required for signalling. Nature 369, 330-333.
    • (1994) Nature , vol.369 , pp. 330-333
    • Nakamura, Y.1    Leonard, W.J.2
  • 29
    • 0029067876 scopus 로고
    • Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor
    • Walter, M.R., et al., & Narula, S.K. (1995). Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor. Nature 376, 230-235.
    • (1995) Nature , vol.376 , pp. 230-235
    • Walter, M.R.1    Narula, S.K.2
  • 30
    • 0028838012 scopus 로고
    • Dimerization of cell surface receptors in signal transduction
    • Heldin, C.-H. (1995). Dimerization of cell surface receptors in signal transduction. Cell 80, 213-223.
    • (1995) Cell , vol.80 , pp. 213-223
    • Heldin, C.-H.1
  • 31
    • 0030744972 scopus 로고    scopus 로고
    • The human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor exits as a preformed receptor complex that can be activated by GM-CSF, interleukin-3, or interleukin-5
    • Woodcock, J.M., McClure, B.J., Stomski, F.C., Elliott, M.J., Bagley, C.J. & Lopez, A.F. (1997). The human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor exits as a preformed receptor complex that can be activated by GM-CSF, interleukin-3, or interleukin-5. Blood 90, 3005-3017.
    • (1997) Blood , vol.90 , pp. 3005-3017
    • Woodcock, J.M.1    McClure, B.J.2    Stomski, F.C.3    Elliott, M.J.4    Bagley, C.J.5    Lopez, A.F.6
  • 32
    • 0031766727 scopus 로고    scopus 로고
    • The structure of human interferon-β: Implications for activity
    • Karpusas, M., Whitty, A., Runkel, L, & Hochman, P. (1998). The structure of human interferon-β: Implications for activity. Cell. Mol. Life Sci. 54, 1203-1216.
    • (1998) Cell. Mol. Life Sci. , vol.54 , pp. 1203-1216
    • Karpusas, M.1    Whitty, A.2    Runkel, L.3    Hochman, P.4
  • 33
    • 0029798402 scopus 로고    scopus 로고
    • Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8 å
    • Livnah, O., et al., & Wilson, I.A. (1996). Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8 å. Science 273, 464-471.
    • (1996) Science , vol.273 , pp. 464-471
    • Livnah, O.1    Wilson, I.A.2
  • 34
    • 0030717635 scopus 로고    scopus 로고
    • Increased potency of an erythropoietin peptide mimetic through covalent dimerization
    • Wrighton, N.C., et al., & Dower, W.J. (1997). Increased potency of an erythropoietin peptide mimetic through covalent dimerization. Nat. Biotechnol. 15, 1261-1265.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 1261-1265
    • Wrighton, N.C.1    Dower, W.J.2
  • 35
    • 0032539954 scopus 로고    scopus 로고
    • Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP-1
    • Johnson, D.L., et al., & Jolliffe, L.K. (1998). Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP-1. Biochemistry 37, 3699-3710.
    • (1998) Biochemistry , vol.37 , pp. 3699-3710
    • Johnson, D.L.1    Jolliffe, L.K.2
  • 36
    • 0031860382 scopus 로고    scopus 로고
    • Signal transduction by the peptide which mimics the activity of thrombopoietin
    • Kimura T., Kaburaki, H., Tsujino, T., Watanabe, Y. & Kato, H. (1998). Signal transduction by the peptide which mimics the activity of thrombopoietin. Biochem. Mol. Biol. Int. 44, 1203-1209.
    • (1998) Biochem. Mol. Biol. Int. , vol.44 , pp. 1203-1209
    • Kimura, T.1    Kaburaki, H.2    Tsujino, T.3    Watanabe, Y.4    Kato, H.5
  • 37
    • 0009575048 scopus 로고    scopus 로고
    • Identification of small molecule mimics of cytokines using reporter-based screens in mammalian cells
    • Miller, S.G. (1998). Identification of small molecule mimics of cytokines using reporter-based screens in mammalian cells. 4th Annual Conference of the Society for Biomolecular Screening, 61-73.
    • (1998) 4th Annual Conference of the Society for Biomolecular Screening , pp. 61-73
    • Miller, S.G.1
  • 38
    • 0019216482 scopus 로고
    • Receptor clustering on a cell surface. I. Theory of receptor cross-linking by ligands bearing two chemically identical functional groups
    • Perelson, A.S. & DeLisi, C. (1980). Receptor clustering on a cell surface. I. Theory of receptor cross-linking by ligands bearing two chemically identical functional groups. Math. Biosci. 48, 71-110.
    • (1980) Math. Biosci. , vol.48 , pp. 71-110
    • Perelson, A.S.1    Delisi, C.2
  • 39
    • 84995826606 scopus 로고
    • Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes
    • Ilondo, M.M., Damholt, A.B., Cunningham, B.A., Wells, J.A., De Meyts, P., & Shymko, R.M. (1994). Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes. Endocrinology 134, 2397-2403.
    • (1994) Endocrinology , vol.134 , pp. 2397-2403
    • Ilondo, M.M.1    Damholt, A.B.2    Cunningham, B.A.3    Wells, J.A.4    De Meyts, P.5    Shymko, R.M.6
  • 40
    • 0031051275 scopus 로고    scopus 로고
    • Dimerization of granulocyte-colony stimulating factor receptor: The Ig plus CRH construct of granulocyte-colony stimulating factor receptor forms a 2:2 complex with a ligand
    • Horan, T.P., Martin, F., Simonet, L., Arakawa, T. & Philo, J.S. (1997). Dimerization of granulocyte-colony stimulating factor receptor: The Ig plus CRH construct of granulocyte-colony stimulating factor receptor forms a 2:2 complex with a ligand. J. Biochem. 121, 370-375.
    • (1997) J. Biochem. , vol.121 , pp. 370-375
    • Horan, T.P.1    Martin, F.2    Simonet, L.3    Arakawa, T.4    Philo, J.S.5
  • 41
    • 0032086337 scopus 로고    scopus 로고
    • Targeting growth factor and cytokine receptors with recombinant peptide libraries
    • Dower, W.J. (1998). Targeting growth factor and cytokine receptors with recombinant peptide libraries. Curr. Opin. Chem. Biol. 2, 328-334.
    • (1998) Curr. Opin. Chem. Biol. , vol.2 , pp. 328-334
    • Dower, W.J.1
  • 42
    • 0030448925 scopus 로고    scopus 로고
    • Kinetic analysis of ligand binding to interleukin-2 receptor complexes created on an optical biosensor surface
    • Myszka, D.G., Arulanantham, P.R., Sana, T., Wu, Z., Morton, T.A. & Ciardelli, T.L. (1996). Kinetic analysis of ligand binding to interleukin-2 receptor complexes created on an optical biosensor surface. Protein Sci. 5, 2468-2478.
    • (1996) Protein Sci. , vol.5 , pp. 2468-2478
    • Myszka, D.G.1    Arulanantham, P.R.2    Sana, T.3    Wu, Z.4    Morton, T.A.5    Ciardelli, T.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.