-
1
-
-
0025162844
-
Structural design and molecular evolution of a cytokine receptor superfamily
-
Bazan, J.F. (1990). Structural design and molecular evolution of a cytokine receptor superfamily. Proc. Natl Acad. Sci. USA 87, 6934-6938.
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 6934-6938
-
-
Bazan, J.F.1
-
2
-
-
0025285859
-
Cytokines: Coordinators of immune and inflammatory responses
-
Arai, K., Lee, F., Miyajima, A., Miyatake, S., Arai, N., & Yokota, T. (1990). Cytokines: Coordinators of immune and inflammatory responses. Annu. Rev. Biochem. 59, 783-836.
-
(1990)
Annu. Rev. Biochem.
, vol.59
, pp. 783-836
-
-
Arai, K.1
Lee, F.2
Miyajima, A.3
Miyatake, S.4
Arai, N.5
Yokota, T.6
-
3
-
-
9444236174
-
Small peptides as potent mimetics of the protein hormone erythropoietin
-
Wrighton, N.C., et al., & Dower, W.J. (1996). Small peptides as potent mimetics of the protein hormone erythropoietin. Science 273, 458-463.
-
(1996)
Science
, vol.273
, pp. 458-463
-
-
Wrighton, N.C.1
Dower, W.J.2
-
4
-
-
0030773876
-
Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine
-
Cwirla, S.E., et al., & Dower, W.J. (1997). Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine. Science 276, 1696-1699.
-
(1997)
Science
, vol.276
, pp. 1696-1699
-
-
Cwirla, S.E.1
Dower, W.J.2
-
5
-
-
0030729340
-
Discovery of a novel thrombopoietin mimic agonist peptide
-
Kimura, T., Kaburaki, H., Miyamoto, S., Katayama, J. & Watanabe, Y. (1997). Discovery of a novel thrombopoietin mimic agonist peptide. J. Biochem. 122, 1046-1051.
-
(1997)
J. Biochem.
, vol.122
, pp. 1046-1051
-
-
Kimura, T.1
Kaburaki, H.2
Miyamoto, S.3
Katayama, J.4
Watanabe, Y.5
-
6
-
-
0032504007
-
A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor
-
Tian, S.-S., et al., & Rosen, J. (1998). A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor. Science 281, 257-259.
-
(1998)
Science
, vol.281
, pp. 257-259
-
-
Tian, S.-S.1
Rosen, J.2
-
7
-
-
0032577533
-
A non-peptide compound which can mimic the effect of thrombopoietin via c-Mpl
-
Kimura, T., Kaburaki, H., Tsujino, T., Ikeda, Y., Kato, H. & Watanabe, Y. (1998). A non-peptide compound which can mimic the effect of thrombopoietin via c-Mpl. FEBS Lett. 428, 250-254.
-
(1998)
FEBS Lett.
, vol.428
, pp. 250-254
-
-
Kimura, T.1
Kaburaki, H.2
Tsujino, T.3
Ikeda, Y.4
Kato, H.5
Watanabe, Y.6
-
8
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ullrich, A. & Schlessinger, J. (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.
-
(1990)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
9
-
-
0028260226
-
Structural and functional basis for hormone binding and receptor oligomerization
-
Wells, J.A. (1994). Structural and functional basis for hormone binding and receptor oligomerization. Curr. Opin. Cell Biol. 6, 163-173.
-
(1994)
Curr. Opin. Cell Biol.
, vol.6
, pp. 163-173
-
-
Wells, J.A.1
-
10
-
-
0027328343
-
The alphas, betas, and kinases of cytokine receptor complexes
-
Stahl, N. & Yancopoulos, G.D. (1993). The alphas, betas, and kinases of cytokine receptor complexes. Cell 74, 587-590.
-
(1993)
Cell
, vol.74
, pp. 587-590
-
-
Stahl, N.1
Yancopoulos, G.D.2
-
11
-
-
0029982521
-
Hematopoietic receptor complexes
-
Wells, J.A. & de Vos, A.M. (1996). Hematopoietic receptor complexes. Annu. Rev. Biochem. 65, 609-634.
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 609-634
-
-
Wells, J.A.1
de Vos, A.M.2
-
12
-
-
0026764441
-
Rational design of potent antagonists to the human growth hormone receptor
-
Fuh, G., Cunningham, B.C., Fukunaga, R., Nagata, S., Goeddel, D.V. & Wells, J.A. (1992). Rational design of potent antagonists to the human growth hormone receptor. Science 256, 1677-1680.
-
(1992)
Science
, vol.256
, pp. 1677-1680
-
-
Fuh, G.1
Cunningham, B.C.2
Fukunaga, R.3
Nagata, S.4
Goeddel, D.V.5
Wells, J.A.6
-
13
-
-
0026577197
-
Homodimerization and constitutive activation of the erythropoietin receptor
-
Watowich, S., Yoshimura, A., Longmore, G.D., Hilton, D.J., Yoshimura, Y. & Lodish, H.F. (1992). Homodimerization and constitutive activation of the erythropoietin receptor. Proc. Natl Acad. Sci. USA 89, 2140-2144.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 2140-2144
-
-
Watowich, S.1
Yoshimura, A.2
Longmore, G.D.3
Hilton, D.J.4
Yoshimura, Y.5
Lodish, H.F.6
-
14
-
-
0031033923
-
Homodimerization of erythropoietin receptor by a bivalent monoclonal antibody triggers cell proliferation and differentiation of erythroid precursors
-
Schneider, H., et al., & Giebel, L.B. (1997). Homodimerization of erythropoietin receptor by a bivalent monoclonal antibody triggers cell proliferation and differentiation of erythroid precursors. Blood 89, 473-482.
-
(1997)
Blood
, vol.89
, pp. 473-482
-
-
Schneider, H.1
Giebel, L.B.2
-
15
-
-
0031008572
-
Characterization of the receptor binding determinants of granulocyte colony stimulating factor
-
Young, D.C., Zhan, H., Cheng, Q.L, Hou, L. & Matthews, D.J. (1997). Characterization of the receptor binding determinants of granulocyte colony stimulating factor. Protein Sci. 6, 1228-1236.
-
(1997)
Protein Sci.
, vol.6
, pp. 1228-1236
-
-
Young, D.C.1
Zhan, H.2
Cheng, Q.L.3
Hou, L.4
Matthews, D.J.5
-
16
-
-
0028832719
-
Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity
-
Alexander, W.S., Metcalf, D. & Dunn, A.R. (1995). Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity. EMBO J. 14, 5569-5578.
-
(1995)
EMBO J.
, vol.14
, pp. 5569-5578
-
-
Alexander, W.S.1
Metcalf, D.2
Dunn, A.R.3
-
17
-
-
0032052221
-
Surrogate thrombopoietin
-
Abe, M., et al. & Masuho, Y. (1998). Surrogate thrombopoietin. Immunol. Lett. 61, 73-78.
-
(1998)
Immunol. Lett.
, vol.61
, pp. 73-78
-
-
Abe, M.1
Masuho, Y.2
-
18
-
-
3543123430
-
An agonist murine monoclonal antibody to the human c-Mpl receptor stimulates megakaryocytopoiesis
-
Deng, B. et al., & Avraham, H. (1998). An agonist murine monoclonal antibody to the human c-Mpl receptor stimulates megakaryocytopoiesis. Blood 92, 1981-1988.
-
(1998)
Blood
, vol.92
, pp. 1981-1988
-
-
Deng, B.1
Avraham, H.2
-
19
-
-
0032540358
-
Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity
-
Clackson, T., Ultsch, M.H., Wells, J.A. & de Vos, A.M. (1998). Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J. Mol. Biol. 277, 1111-1128.
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 1111-1128
-
-
Clackson, T.1
Ultsch, M.H.2
Wells, J.A.3
de Vos, A.M.4
-
20
-
-
0032570710
-
Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies
-
Rowlinson, S.W., et al., & Waters, M.J. (1998). Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies. J. Biol. Chem. 273, 5307-5314.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5307-5314
-
-
Rowlinson, S.W.1
Waters, M.J.2
-
21
-
-
0032188942
-
Efficiency of signalling through cytokine receptors depends critically on receptor orientation
-
Syed, R.S., et al., & Stroud, R.M. (1998). Efficiency of signalling through cytokine receptors depends critically on receptor orientation. Nature 395, 511-516.
-
(1998)
Nature
, vol.395
, pp. 511-516
-
-
Syed, R.S.1
Stroud, R.M.2
-
23
-
-
0026089503
-
Erythropoietin receptors induced by dimethyl sulfoxide exhibit positive cooperativity associated with an amplified biologic response
-
Yonekura, S., Chern, Y., Donahue, K.A., Feldman, L, Vanasse, G.J. & Sytkowski, A.J. (1991). Erythropoietin receptors induced by dimethyl sulfoxide exhibit positive cooperativity associated with an amplified biologic response. Proc. Natl Acad. Sci. USA 88, 2535-2539.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 2535-2539
-
-
Yonekura, S.1
Chern, Y.2
Donahue, K.A.3
Feldman, L.4
Vanasse, G.J.5
Sytkowski, A.J.6
-
24
-
-
0025870016
-
Comparison of the effects of hypertonic sucrose and intracellular potassium depletion on growth hormone receptor binding kinetics and down-regulation in IM-9 cells: Evidence for a sequential block of receptor-mediated endocytosis
-
Ilondo, M.M, Smal, J., de Meyts, P. & Courtoy, P.J. (1991). Comparison of the effects of hypertonic sucrose and intracellular potassium depletion on growth hormone receptor binding kinetics and down-regulation in IM-9 cells: Evidence for a sequential block of receptor-mediated endocytosis. Endocrinology 128, 1597-1602.
-
(1991)
Endocrinology
, vol.128
, pp. 1597-1602
-
-
Ilondo, M.M.1
Smal, J.2
de Meyts, P.3
Courtoy, P.J.4
-
25
-
-
0344573809
-
Growth hormone binding affinity for its receptor surpasses the requirements for cellular activity
-
Pearce, K.H. Jr., Cunningham, B.C., Fuh, G., Teeri, G. & Wells, J.A. (1999). Growth hormone binding affinity for its receptor surpasses the requirements for cellular activity. Biochemistry 38, 81 -89.
-
(1999)
Biochemistry
, vol.38
, pp. 81-89
-
-
Pearce K.H., Jr.1
Cunningham, B.C.2
Fuh, G.3
Teeri, G.4
Wells, J.A.5
-
26
-
-
0027451432
-
Two distinct functional sites of human interleukin 4 are identified by variants impaired in either receptor binding or receptor activation
-
Kruse, N., Shen, B.-J., Arnold, S., Tony, H.-P., Muller, T. & Sebald, W. (1993). Two distinct functional sites of human interleukin 4 are identified by variants impaired in either receptor binding or receptor activation. EMBO J. 12, 5121-5129.
-
(1993)
EMBO J.
, vol.12
, pp. 5121-5129
-
-
Kruse, N.1
Shen, B.-J.2
Arnold, S.3
Tony, H.-P.4
Muller, T.5
Sebald, W.6
-
27
-
-
0032573092
-
Interaction affinity between cytokine receptor components on the cell surface
-
Whitty, A., et al., & Burkly, L.C. (1998). Interaction affinity between cytokine receptor components on the cell surface. Proc. Natl Acad. Sci. USA 95, 13165-13170.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 13165-13170
-
-
Whitty, A.1
Burkly, L.C.2
-
28
-
-
0028286627
-
Heterodimerization of the IL-2 receptor β- and γ-chain cytoplasmic domians is required for signalling
-
Nakamura, Y., et al., & Leonard, W.J. (1994.) Heterodimerization of the IL-2 receptor β- and γ-chain cytoplasmic domians is required for signalling. Nature 369, 330-333.
-
(1994)
Nature
, vol.369
, pp. 330-333
-
-
Nakamura, Y.1
Leonard, W.J.2
-
29
-
-
0029067876
-
Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor
-
Walter, M.R., et al., & Narula, S.K. (1995). Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor. Nature 376, 230-235.
-
(1995)
Nature
, vol.376
, pp. 230-235
-
-
Walter, M.R.1
Narula, S.K.2
-
30
-
-
0028838012
-
Dimerization of cell surface receptors in signal transduction
-
Heldin, C.-H. (1995). Dimerization of cell surface receptors in signal transduction. Cell 80, 213-223.
-
(1995)
Cell
, vol.80
, pp. 213-223
-
-
Heldin, C.-H.1
-
31
-
-
0030744972
-
The human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor exits as a preformed receptor complex that can be activated by GM-CSF, interleukin-3, or interleukin-5
-
Woodcock, J.M., McClure, B.J., Stomski, F.C., Elliott, M.J., Bagley, C.J. & Lopez, A.F. (1997). The human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor exits as a preformed receptor complex that can be activated by GM-CSF, interleukin-3, or interleukin-5. Blood 90, 3005-3017.
-
(1997)
Blood
, vol.90
, pp. 3005-3017
-
-
Woodcock, J.M.1
McClure, B.J.2
Stomski, F.C.3
Elliott, M.J.4
Bagley, C.J.5
Lopez, A.F.6
-
32
-
-
0031766727
-
The structure of human interferon-β: Implications for activity
-
Karpusas, M., Whitty, A., Runkel, L, & Hochman, P. (1998). The structure of human interferon-β: Implications for activity. Cell. Mol. Life Sci. 54, 1203-1216.
-
(1998)
Cell. Mol. Life Sci.
, vol.54
, pp. 1203-1216
-
-
Karpusas, M.1
Whitty, A.2
Runkel, L.3
Hochman, P.4
-
33
-
-
0029798402
-
Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8 å
-
Livnah, O., et al., & Wilson, I.A. (1996). Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8 å. Science 273, 464-471.
-
(1996)
Science
, vol.273
, pp. 464-471
-
-
Livnah, O.1
Wilson, I.A.2
-
34
-
-
0030717635
-
Increased potency of an erythropoietin peptide mimetic through covalent dimerization
-
Wrighton, N.C., et al., & Dower, W.J. (1997). Increased potency of an erythropoietin peptide mimetic through covalent dimerization. Nat. Biotechnol. 15, 1261-1265.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 1261-1265
-
-
Wrighton, N.C.1
Dower, W.J.2
-
35
-
-
0032539954
-
Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP-1
-
Johnson, D.L., et al., & Jolliffe, L.K. (1998). Identification of a 13 amino acid peptide mimetic of erythropoietin and description of amino acids critical for the mimetic activity of EMP-1. Biochemistry 37, 3699-3710.
-
(1998)
Biochemistry
, vol.37
, pp. 3699-3710
-
-
Johnson, D.L.1
Jolliffe, L.K.2
-
36
-
-
0031860382
-
Signal transduction by the peptide which mimics the activity of thrombopoietin
-
Kimura T., Kaburaki, H., Tsujino, T., Watanabe, Y. & Kato, H. (1998). Signal transduction by the peptide which mimics the activity of thrombopoietin. Biochem. Mol. Biol. Int. 44, 1203-1209.
-
(1998)
Biochem. Mol. Biol. Int.
, vol.44
, pp. 1203-1209
-
-
Kimura, T.1
Kaburaki, H.2
Tsujino, T.3
Watanabe, Y.4
Kato, H.5
-
37
-
-
0009575048
-
Identification of small molecule mimics of cytokines using reporter-based screens in mammalian cells
-
Miller, S.G. (1998). Identification of small molecule mimics of cytokines using reporter-based screens in mammalian cells. 4th Annual Conference of the Society for Biomolecular Screening, 61-73.
-
(1998)
4th Annual Conference of the Society for Biomolecular Screening
, pp. 61-73
-
-
Miller, S.G.1
-
38
-
-
0019216482
-
Receptor clustering on a cell surface. I. Theory of receptor cross-linking by ligands bearing two chemically identical functional groups
-
Perelson, A.S. & DeLisi, C. (1980). Receptor clustering on a cell surface. I. Theory of receptor cross-linking by ligands bearing two chemically identical functional groups. Math. Biosci. 48, 71-110.
-
(1980)
Math. Biosci.
, vol.48
, pp. 71-110
-
-
Perelson, A.S.1
Delisi, C.2
-
39
-
-
84995826606
-
Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes
-
Ilondo, M.M., Damholt, A.B., Cunningham, B.A., Wells, J.A., De Meyts, P., & Shymko, R.M. (1994). Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes. Endocrinology 134, 2397-2403.
-
(1994)
Endocrinology
, vol.134
, pp. 2397-2403
-
-
Ilondo, M.M.1
Damholt, A.B.2
Cunningham, B.A.3
Wells, J.A.4
De Meyts, P.5
Shymko, R.M.6
-
40
-
-
0031051275
-
Dimerization of granulocyte-colony stimulating factor receptor: The Ig plus CRH construct of granulocyte-colony stimulating factor receptor forms a 2:2 complex with a ligand
-
Horan, T.P., Martin, F., Simonet, L., Arakawa, T. & Philo, J.S. (1997). Dimerization of granulocyte-colony stimulating factor receptor: The Ig plus CRH construct of granulocyte-colony stimulating factor receptor forms a 2:2 complex with a ligand. J. Biochem. 121, 370-375.
-
(1997)
J. Biochem.
, vol.121
, pp. 370-375
-
-
Horan, T.P.1
Martin, F.2
Simonet, L.3
Arakawa, T.4
Philo, J.S.5
-
41
-
-
0032086337
-
Targeting growth factor and cytokine receptors with recombinant peptide libraries
-
Dower, W.J. (1998). Targeting growth factor and cytokine receptors with recombinant peptide libraries. Curr. Opin. Chem. Biol. 2, 328-334.
-
(1998)
Curr. Opin. Chem. Biol.
, vol.2
, pp. 328-334
-
-
Dower, W.J.1
-
42
-
-
0030448925
-
Kinetic analysis of ligand binding to interleukin-2 receptor complexes created on an optical biosensor surface
-
Myszka, D.G., Arulanantham, P.R., Sana, T., Wu, Z., Morton, T.A. & Ciardelli, T.L. (1996). Kinetic analysis of ligand binding to interleukin-2 receptor complexes created on an optical biosensor surface. Protein Sci. 5, 2468-2478.
-
(1996)
Protein Sci.
, vol.5
, pp. 2468-2478
-
-
Myszka, D.G.1
Arulanantham, P.R.2
Sana, T.3
Wu, Z.4
Morton, T.A.5
Ciardelli, T.L.6
|