Recent progress in the discovery of antagonists acting at P2X7 receptor

Expert Opinion on Therapeutic Patents

Volumn 15, Issue 3, 2005, Pages 271-287

  Romagnoli, Romeo ^a   Baraldi, Pier Giovanni ^a   Di Virgilio, Francesco ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

Extracellular ATP; Inflammatory process; Ionotropic receptor KN 62; P2X7 (purino) receptor

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 2 CHLOROAMIDE DERIVATIVE; 2 CHLOROBENZAMIDE DERIVATIVE; 2,3 DIALDEHYDE ADENOSINE TRIPHOSPHATE; 3 NITROBENZYLOXYCARBONYL DERIVATIVE; 4 AMINOTOLUNSULFONATE DERIVATIVE; 4 CHLOROAMIDE DERIVATIVE; 4 NITROTOLUNSULFONATE DERIVATIVE; 5 (N,N HEXAMETHYLENE)AMILORIDE; 5' (4 FLUOROSULFONYLBENZOYL)ADENOSINE; ADAMANTANE; ADAMANTANE DERIVATIVE; ADENOSINE TRIPHOSPHATE; AMIDE; BENZENAMIDE DERIVATIVE; BRILLIANT BLUE; BRILLIANT BLUE G; CALMIDAZOLIUM; CIBACRON BLUE F3GA; CYTOKINE; MRS 2409; MRS 2447; MRS 2452; MRS 2464; N [1 [4 (5 ISOQUINOLINESULFONYL) ALPHA METHYLBENZYL] 2 (4 PHENYL 1 PIPERAZINYL)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NITRIC OXIDE; PIPERAZINE DERIVATIVE; PURINE P2X7 RECEPTOR; PURINE P2X7 RECEPTOR BLOCKING AGENT; RECEPTOR BLOCKING AGENT; SURAMIN; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

CYTOKINE RELEASE; CYTOTOXICITY; DRUG CLEARANCE; DRUG DESIGN; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; HIGH THROUGHPUT SCREENING; HUMAN; INFLAMMATION; NONHUMAN; REVIEW; STRUCTURE ACTIVITY RELATION;

EID: 15544370681     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.15.3.271     Document Type: Review

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