The isoquinoline derivative KN-62 a potent antagonist of the P2Z-receptor of human lymphocytes

British Journal of Pharmacology

Volumn 120, Issue 8, 1997, Pages 1483-1490

  Gargett, Caroline E ^a   Wiley, James S ^b  

^a AUSTIN HEALTH   (Australia)

^b NEPEAN HOSPITAL   (Australia)

Author keywords

Antagonist; Cation channel; Extracellular ATP receptor; Isoquinolinesulphonamide; KN 04; KN 62; L selectin; Lymphocyte; Lymphocytes (human leukaemic); P2Y2 receptor; P2Z receptor; Phospholipase D

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; ADENOSINE TRIPHOSPHATE; BARIUM ION; ETHIDIUM; FURA 2; ISOQUINOLINE DERIVATIVE; L SELECTIN; LYMPHOCYTE RECEPTOR; OLEIC ACID; PHOSPHOLIPASE D; PROTEIN KINASE (CALCIUM,CALMODULIN) II; PROTEIN KINASE INHIBITOR; PURINE P2 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PURINERGIC RECEPTOR STIMULATING AGENT; RECEPTOR SUBTYPE; TRITIUM;

ARTICLE; CATION TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME REGULATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; ISOTOPE LABELING; LYMPHOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING;

EID: 0030977216     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701081     Document Type: Article

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