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Volumn 174, Issue 7, 2005, Pages 4185-4192

Maintenance of pulmonary Th1 effector function in chronic tuberculosis requires persistent IL-12 production

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12P40;

EID: 15444375415     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.7.4185     Document Type: Article
Times cited : (104)

References (63)
  • 1
    • 0034977241 scopus 로고    scopus 로고
    • Tuberculosis: Latency and reactivation
    • Flynn, J. L., and J. Chan. 2001. Tuberculosis: latency and reactivation. Infect. Immun. 69:4195.
    • (2001) Infect. Immun. , vol.69 , pp. 4195
    • Flynn, J.L.1    Chan, J.2
  • 2
    • 0033846833 scopus 로고    scopus 로고
    • Restraining mycobacteria: Role of granulomas in mycobacterial infections
    • Saunders, B. M., and A. M. Cooper. 2000. Restraining mycobacteria: role of granulomas in mycobacterial infections. Immunol. Cell Biol. 78:334.
    • (2000) Immunol. Cell Biol. , vol.78 , pp. 334
    • Saunders, B.M.1    Cooper, A.M.2
  • 5
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3:133.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 133
    • Trinchieri, G.1
  • 6
    • 0036219062 scopus 로고    scopus 로고
    • Genetic dissection of immunity to mycobacteria: The human model
    • Casanova, J. L., and L. Abel. 2002. Genetic dissection of immunity to mycobacteria: the human model. Amu. Rev. Immunol. 20:581.
    • (2002) Amu. Rev. Immunol. , vol.20 , pp. 581
    • Casanova, J.L.1    Abel, L.2
  • 7
    • 0038759100 scopus 로고    scopus 로고
    • The role of interleukin-12 in human infectious diseases: Only a faint signature
    • Fieschi, C., and J. L. Casanova. 2003. The role of interleukin-12 in human infectious diseases: only a faint signature. Eur. J. Immunol. 33:1461.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1461
    • Fieschi, C.1    Casanova, J.L.2
  • 8
    • 0034955237 scopus 로고    scopus 로고
    • Interleukin-12 as successful adjuvant in tuberculosis treatment
    • Greinert, U., M. Ernst, M. Schlaak, and P. Entzian. 2001. Interleukin-12 as successful adjuvant in tuberculosis treatment. Eur. Respir. J. 17:1049.
    • (2001) Eur. Respir. J. , vol.17 , pp. 1049
    • Greinert, U.1    Ernst, M.2    Schlaak, M.3    Entzian, P.4
  • 9
    • 0029078676 scopus 로고
    • IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection
    • Flynn, J. L., M. M. Goldstein, K. J. Triebold, J. Sypek, S. Wolf, and B. R. Bloom. 1995. IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection. J. Immunol. 155:2515.
    • (1995) J. Immunol. , vol.155 , pp. 2515
    • Flynn, J.L.1    Goldstein, M.M.2    Triebold, K.J.3    Sypek, J.4    Wolf, S.5    Bloom, B.R.6
  • 10
    • 2142828548 scopus 로고    scopus 로고
    • Interleukin-12 therapy reduces the number of immune cells and pathology in lungs of mice infected with Mycobacterium tuberculosis
    • Nolt, D., and J. L. Flynn. 2004. Interleukin-12 therapy reduces the number of immune cells and pathology in lungs of mice infected with Mycobacterium tuberculosis. Infect. Immun. 72:2976.
    • (2004) Infect. Immun. , vol.72 , pp. 2976
    • Nolt, D.1    Flynn, J.L.2
  • 11
    • 0028947010 scopus 로고
    • The role of interleukin-12 in acquired immunity to Mycobacterium tuberculosis infection
    • Cooper, A. M., A. D. Roberts, E. R. Rhoades, J. E. Callahan, D. M. Getzy, and I. M. Orme. 1995. The role of interleukin-12 in acquired immunity to Mycobacterium tuberculosis infection. Immunology 84:423.
    • (1995) Immunology , vol.84 , pp. 423
    • Cooper, A.M.1    Roberts, A.D.2    Rhoades, E.R.3    Callahan, J.E.4    Getzy, D.M.5    Orme, I.M.6
  • 12
    • 0030790652 scopus 로고    scopus 로고
    • Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis
    • Cooper, A. M., J. Magram, J. Ferrante, and I. M. Orme. 1997. Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis. J. Exp. Med. 186:39.
    • (1997) J. Exp. Med. , vol.186 , pp. 39
    • Cooper, A.M.1    Magram, J.2    Ferrante, J.3    Orme, I.M.4
  • 13
    • 0036467445 scopus 로고    scopus 로고
    • Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present
    • Cooper, A. M., A. Kipnis, J. Turner, J. Magram, J. Ferrante, and I. M. Orme. 2002. Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present. J. Immunol. 168:1322.
    • (2002) J. Immunol. , vol.168 , pp. 1322
    • Cooper, A.M.1    Kipnis, A.2    Turner, J.3    Magram, J.4    Ferrante, J.5    Orme, I.M.6
  • 15
    • 12044249483 scopus 로고
    • IL-12: Initiation cytokine for cell-mediated immunity
    • Scott, P. 1993. IL-12: initiation cytokine for cell-mediated immunity. Science 260:496.
    • (1993) Science , vol.260 , pp. 496
    • Scott, P.1
  • 16
    • 0030266857 scopus 로고    scopus 로고
    • Differential roles for IL-12 in the maintenance of immune responses in infectious versus autoimmune disease
    • Seder, R. A., B. L. Kelsall, and D. Jankovic. 1996. Differential roles for IL-12 in the maintenance of immune responses in infectious versus autoimmune disease. J. Immunol. 157:2745.
    • (1996) J. Immunol. , vol.157 , pp. 2745
    • Seder, R.A.1    Kelsall, B.L.2    Jankovic, D.3
  • 17
    • 0034661678 scopus 로고    scopus 로고
    • IL-12 is required to maintain a Th1 response during Leishmania major infection
    • Park, A. Y., B. D. Hondowicz, and P. Scott. 2000. IL-12 is required to maintain a Th1 response during Leishmania major infection. J. Immunol. 165:896.
    • (2000) J. Immunol. , vol.165 , pp. 896
    • Park, A.Y.1    Hondowicz, B.D.2    Scott, P.3
  • 18
    • 0034682553 scopus 로고    scopus 로고
    • The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge
    • Stobie, L., S. Gurunathan, C. Prussin, D. L. Sacks, N. Glaichenhaus, C. Y. Wu, and R. A. Seder. 2000. The role of antigen and IL-12 in sustaining Th1 memory cells in vivo: IL-12 is required to maintain memory/effector Th1 cells sufficient to mediate protection to an infectious parasite challenge. Proc. Natl. Acad. Sci. USA 97:8427.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8427
    • Stobie, L.1    Gurunathan, S.2    Prussin, C.3    Sacks, D.L.4    Glaichenhaus, N.5    Wu, C.Y.6    Seder, R.A.7
  • 19
    • 0034662258 scopus 로고    scopus 로고
    • Cutting edge: IL-12 is required for the maintenance of IFN-γ production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii
    • Yap, G., M. Pesin, and A. Sher. 2000. Cutting edge: IL-12 is required for the maintenance of IFN-γ production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii. J. Immunol. 165:628.
    • (2000) J. Immunol. , vol.165 , pp. 628
    • Yap, G.1    Pesin, M.2    Sher, A.3
  • 20
    • 0034193034 scopus 로고    scopus 로고
    • Up-regulation of VCAM-1 and differential expansion of β integrin-expressing T lymphocytes are associated with immunity to pulmonary Mycobacterium tuberculosis infection
    • Feng, C. G., W. J. Britton, U. Palendira, N. L. Groat, H. Briscoe, and A. G. Bean. 2000. Up-regulation of VCAM-1 and differential expansion of β integrin-expressing T lymphocytes are associated with immunity to pulmonary Mycobacterium tuberculosis infection. J. Immunol. 164:4853.
    • (2000) J. Immunol. , vol.164 , pp. 4853
    • Feng, C.G.1    Britton, W.J.2    Palendira, U.3    Groat, N.L.4    Briscoe, H.5    Bean, A.G.6
  • 21
    • 0037505421 scopus 로고    scopus 로고
    • Increased interleukin-10 expression is not responsible for failure of T helper 1 immunity to resolve airborne Mycobacterium tuberculosis infection in mice
    • Jung, Y. J., L. Ryan, R. LaCourse, and R. J. North. 2003. Increased interleukin-10 expression is not responsible for failure of T helper 1 immunity to resolve airborne Mycobacterium tuberculosis infection in mice. Immunology 109:295.
    • (2003) Immunology , vol.109 , pp. 295
    • Jung, Y.J.1    Ryan, L.2    LaCourse, R.3    North, R.J.4
  • 24
    • 0032792687 scopus 로고    scopus 로고
    • + T cells primed for production of type 1 cytokines in the lungs of Mycobacterium tuberculosis-infected mice
    • + T cells primed for production of type 1 cytokines in the lungs of Mycobacterium tuberculosis-infected mice. Infect. Immun. 67:3980.
    • (1999) Infect. Immun. , vol.67 , pp. 3980
    • Serbina, N.V.1    Flynn, J.L.2
  • 25
    • 0034617993 scopus 로고    scopus 로고
    • + T cells causes reactivation of murine persistent tuberculosis despite continued expression of interferon γ and nitric oxide synthase 2
    • + T cells causes reactivation of murine persistent tuberculosis despite continued expression of interferon γ and nitric oxide synthase 2. J. Exp. Med. 192:347.
    • (2000) J. Exp. Med. , vol.192 , pp. 347
    • Scanga, C.A.1    Mohan, V.P.2    Yu, K.3    Joseph, H.4    Tanaka, K.5    Chan, J.6    Flynn, J.L.7
  • 26
    • 0035118698 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor α on host immune response in chronic persistent tuberculosis: Possible role for limiting pathology
    • Mohan, V. P., C. A. Scanga, K. Yu, H. M. Scott, K. E. Tanaka, E. Tsang, M. M. Tsai, J. L. Flynn, and J. Chan. 2001. Effects of tumor necrosis factor α on host immune response in chronic persistent tuberculosis: possible role for limiting pathology. Infect. Immun. 69:1847.
    • (2001) Infect. Immun. , vol.69 , pp. 1847
    • Mohan, V.P.1    Scanga, C.A.2    Yu, K.3    Scott, H.M.4    Tanaka, K.E.5    Tsang, E.6    Tsai, M.M.7    Flynn, J.L.8    Chan, J.9
  • 27
    • 0042834294 scopus 로고    scopus 로고
    • Reactivation of latent tuberculosis infection in TNF-deficient mice
    • Botha, T., and B. Ryffel. 2003. Reactivation of latent tuberculosis infection in TNF-deficient mice. J. Immunol. 171:3110.
    • (2003) J. Immunol. , vol.171 , pp. 3110
    • Botha, T.1    Ryffel, B.2
  • 28
    • 0032794697 scopus 로고    scopus 로고
    • Reactivation of latent tuberculosis: Variations on the Cornell murine model
    • Scanga, C. A., V. P. Mohan, H. Joseph, K. Yu, J. Chan, and J. L. Flynn. 1999. Reactivation of latent tuberculosis: variations on the Cornell murine model. Infect. Immun. 67:4531.
    • (1999) Infect. Immun. , vol.67 , pp. 4531
    • Scanga, C.A.1    Mohan, V.P.2    Joseph, H.3    Yu, K.4    Chan, J.5    Flynn, J.L.6
  • 30
    • 0032519735 scopus 로고    scopus 로고
    • Effects of aminoguanidine on latent murine tuberculosis
    • Flynn, J. L., C. A. Scanga, K. E. Tanaka, and J. Chan. 1998. Effects of aminoguanidine on latent murine tuberculosis. J. Immunol. 160:1796.
    • (1998) J. Immunol. , vol.160 , pp. 1796
    • Flynn, J.L.1    Scanga, C.A.2    Tanaka, K.E.3    Chan, J.4
  • 31
    • 0027939611 scopus 로고
    • Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii
    • Gazzinelli, R. T., M. Wysocka, S. Hayashi, E. Y. Denkers, S. Hieny, P. Caspar, G. Trinchieri, and A. Sher. 1994. Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii. J. Immunol. 153:2533.
    • (1994) J. Immunol. , vol.153 , pp. 2533
    • Gazzinelli, R.T.1    Wysocka, M.2    Hayashi, S.3    Denkers, E.Y.4    Hieny, S.5    Caspar, P.6    Trinchieri, G.7    Sher, A.8
  • 33
    • 0032555904 scopus 로고    scopus 로고
    • A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type I cells
    • Kaplan, M. H., A. L. Wurster, and M. J. Grusby. 1998. A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type I cells. J. Exp. Med. 188:1191.
    • (1998) J. Exp. Med. , vol.188 , pp. 1191
    • Kaplan, M.H.1    Wurster, A.L.2    Grusby, M.J.3
  • 36
    • 0036604064 scopus 로고    scopus 로고
    • The role of IL-12 in maintaining resistance to Leishmania major
    • Park, A. Y., B. Hondowicz, M. Kopf, and P. Scott. 2002. The role of IL-12 in maintaining resistance to Leishmania major. J. Immunol. 168:5771.
    • (2002) J. Immunol. , vol.168 , pp. 5771
    • Park, A.Y.1    Hondowicz, B.2    Kopf, M.3    Scott, P.4
  • 37
    • 0027075937 scopus 로고
    • IL-12 augments antigen-dependent proliferation of activated T lymphocytes
    • Bertagnolli, M. M., B. Y. Lin, D. Young, and S. H. Herrmann. 1992. IL-12 augments antigen-dependent proliferation of activated T lymphocytes. J. Immunol. 149:3778.
    • (1992) J. Immunol. , vol.149 , pp. 3778
    • Bertagnolli, M.M.1    Lin, B.Y.2    Young, D.3    Herrmann, S.H.4
  • 38
    • 0035500288 scopus 로고    scopus 로고
    • Dual role of the IL-12/IFN-γ axis in the development of autoimmune myocarditis: Induction by IL-12 and protection by IFN-γ
    • Eriksson, U., M. O. Kurrer, W. Sebald, F. Brombacher, and M. Kopf. 2001. Dual role of the IL-12/IFN-γ axis in the development of autoimmune myocarditis: induction by IL-12 and protection by IFN-γ. J. Immunol. 167:5464.
    • (2001) J. Immunol. , vol.167 , pp. 5464
    • Eriksson, U.1    Kurrer, M.O.2    Sebald, W.3    Brombacher, F.4    Kopf, M.5
  • 41
    • 0033564668 scopus 로고    scopus 로고
    • Extinction of IL-12 signaling promotes Fas-mediated apoptosis of antigen-specific T cells
    • Marth, T., M. Zeitz, B. R. Ludviksson, W. Strober, and B. L. Kelsall. 1999. Extinction of IL-12 signaling promotes Fas-mediated apoptosis of antigen-specific T cells. J. Immunol. 162:7233.
    • (1999) J. Immunol. , vol.162 , pp. 7233
    • Marth, T.1    Zeitz, M.2    Ludviksson, B.R.3    Strober, W.4    Kelsall, B.L.5
  • 42
    • 0035879183 scopus 로고    scopus 로고
    • IL-12 decreases activation-induced cell death in human naive Th cells costimulated by intercellular adhesion molecule-1. I. IL-12 alters caspase processing and inhibits enzyme function
    • Palmer, E. M., L. Farrokh-Siar, J. Maguire van Seventer, and G. A. van Seventer. 2001. IL-12 decreases activation-induced cell death in human naive Th cells costimulated by intercellular adhesion molecule-1. I. IL-12 alters caspase processing and inhibits enzyme function. J. Immunol. 167:749.
    • (2001) J. Immunol. , vol.167 , pp. 749
    • Palmer, E.M.1    Farrokh-Siar, L.2    Maguire Van Seventer, J.3    Van Seventer, G.A.4
  • 43
    • 0037442018 scopus 로고    scopus 로고
    • Persistence and turnover of antigen-specific CD4 T cells during chronic tuberculosis infection in the mouse
    • Winslow, G. M., A. D. Roberts, M. A. Blackman, and D. L. Woodland. 2003. Persistence and turnover of antigen-specific CD4 T cells during chronic tuberculosis infection in the mouse. J. Immunol. 170:2046.
    • (2003) J. Immunol. , vol.170 , pp. 2046
    • Winslow, G.M.1    Roberts, A.D.2    Blackman, M.A.3    Woodland, D.L.4
  • 44
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann, B., R. Lesley, B. Blom, J. C. Timans, Y. Xu, B. Hunte, F. Vega, N. Yu, J. Wang, K. Singh, et al. 2000. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 13:715.
    • (2000) Immunity , vol.13 , pp. 715
    • Oppmann, B.1    Lesley, R.2    Blom, B.3    Timans, J.C.4    Xu, Y.5    Hunte, B.6    Vega, F.7    Yu, N.8    Wang, J.9    Singh, K.10
  • 48
    • 1342324752 scopus 로고    scopus 로고
    • Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice
    • Ghilardi, N., N. Kljavin, Q. Chen, S. Lucas, A. L. Gurney, and F. J. De Sauvage. 2004. Compromised humoral and delayed-type hypersensitivity responses in IL-23-deficient mice. J. Immunol. 172:2827.
    • (2004) J. Immunol. , vol.172 , pp. 2827
    • Ghilardi, N.1    Kljavin, N.2    Chen, Q.3    Lucas, S.4    Gurney, A.L.5    De Sauvage, F.J.6
  • 50
    • 0028124945 scopus 로고
    • Immunohistochemical analysis of cell composition and in situ cytokine expression in HIV- and non-HIV-associated tuberculous lymphadenitis
    • Muller, H., and S. Kruger. 1994. Immunohistochemical analysis of cell composition and in situ cytokine expression in HIV- and non-HIV-associated tuberculous lymphadenitis. Immunobiology 191:354.
    • (1994) Immunobiology , vol.191 , pp. 354
    • Muller, H.1    Kruger, S.2
  • 51
    • 0036274370 scopus 로고    scopus 로고
    • Tuberculosis unleashed: The impact of human immunodeficiency virus infection on the host granulomatous response to Mycobacterium tuberculosis
    • Lawn, S. D., S. T. Butera, and T. M. Shinnick. 2002. Tuberculosis unleashed: the impact of human immunodeficiency virus infection on the host granulomatous response to Mycobacterium tuberculosis. Microbes Infect. 4:635.
    • (2002) Microbes Infect. , vol.4 , pp. 635
    • Lawn, S.D.1    Butera, S.T.2    Shinnick, T.M.3
  • 52
    • 0142211129 scopus 로고    scopus 로고
    • + T cells mediate IFN-γ-independent control of Mycobacterium tuberculosis infection both in vitro and in vivo
    • + T cells mediate IFN-γ-independent control of Mycobacterium tuberculosis infection both in vitro and in vivo. J. Immunol. 171:4689.
    • (2003) J. Immunol. , vol.171 , pp. 4689
    • Cowley, S.C.1    Elkins, K.L.2
  • 54
    • 8044250881 scopus 로고    scopus 로고
    • Regulation of the interleukin (IL)-12Rβ2 subunit expression in developing T helper 1 (Th1) and Th2 cells
    • Szabo, S. J., A. S. Dighe, U. Gubler, and K. M. Murphy. 1997. Regulation of the interleukin (IL)-12Rβ2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 185:817.
    • (1997) J. Exp. Med. , vol.185 , pp. 817
    • Szabo, S.J.1    Dighe, A.S.2    Gubler, U.3    Murphy, K.M.4
  • 56
    • 3943106044 scopus 로고    scopus 로고
    • Increased Interleukin-4 production by CD8 and γδ T cells in health-care workers is associated with the subsequent development of active tuberculosis
    • Ordway, D. J., L. Costa, M. Martins, H. Silveira, L. Amaral, M. J. Arroz, F. A. Ventura, and H. M. Dockrell. 2004. Increased Interleukin-4 production by CD8 and γδ T cells in health-care workers is associated with the subsequent development of active tuberculosis. J. Infect. Dis. 190:756.
    • (2004) J. Infect. Dis. , vol.190 , pp. 756
    • Ordway, D.J.1    Costa, L.2    Martins, M.3    Silveira, H.4    Amaral, L.5    Arroz, M.J.6    Ventura, F.A.7    Dockrell, H.M.8
  • 57
    • 2442692860 scopus 로고    scopus 로고
    • Healthy individuals that control a latent infection with Mycobacterium tuberculosis express high levels of Th1 cytokines and the IL-4 antagonist IL-4δ2
    • Demissie, A., M. Abebe, A. Aseffa, G. Rook, H. Fletcher, A. Zumla, K. Weldingh, I. Brock, P. Andersen, and T. M. Doherty. 2004. Healthy individuals that control a latent infection with Mycobacterium tuberculosis express high levels of Th1 cytokines and the IL-4 antagonist IL-4δ2. J. Immunol. 172:6938.
    • (2004) J. Immunol. , vol.172 , pp. 6938
    • Demissie, A.1    Abebe, M.2    Aseffa, A.3    Rook, G.4    Fletcher, H.5    Zumla, A.6    Weldingh, K.7    Brock, I.8    Andersen, P.9    Doherty, T.M.10
  • 59
    • 0031757985 scopus 로고    scopus 로고
    • Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection
    • Gurunathan, S., C. Prussin, D. L. Sacks, and R. A. Seder. 1998. Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection. Nat. Med. 4:1409.
    • (1998) Nat. Med. , vol.4 , pp. 1409
    • Gurunathan, S.1    Prussin, C.2    Sacks, D.L.3    Seder, R.A.4
  • 60
    • 0036127003 scopus 로고    scopus 로고
    • Coexpression of interleukin-12 chains by a self-splicing vector increases the protective cellular immune response of DNA and Mycobacterium bovis BCG vaccines against Mycobacterium tuberculosis
    • Palendira, U., A. T. Kamath, C. G. Feng, E. Martin, P. J. Chaplin, J. A. Triccas, and W. J. Britton. 2002. Coexpression of interleukin-12 chains by a self-splicing vector increases the protective cellular immune response of DNA and Mycobacterium bovis BCG vaccines against Mycobacterium tuberculosis. Infect. Immun. 70:1949.
    • (2002) Infect. Immun. , vol.70 , pp. 1949
    • Palendira, U.1    Kamath, A.T.2    Feng, C.G.3    Martin, E.4    Chaplin, P.J.5    Triccas, J.A.6    Britton, W.J.7
  • 63


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