Early emergence of CD8+ T cells primed for production of type 1 cytokines in the lungs of Mycobacterium tuberculosis-infected mice

Infection and Immunity

Volumn 67, Issue 8, 1999, Pages 3980-3988

  Serbina, Natalya V ^a   Flynn, JoAnne L ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON;

ADOPTIVE TRANSFER; ANIMAL CELL; ARTICLE; CELL KILLING; CELL PROTECTION; CYTOKINE RELEASE; FLOW CYTOMETRY; GENE TARGETING; IMMUNE RESPONSE; LUNG TUBERCULOSIS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0032792687     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.8.3980-3988.1999     Document Type: Article

References (58)

1. Almeida, G. B., C. Chitale, I. Boutsikakis, J.-Y. Geng, H. Doo, S. He, and J. L. Ho. 1998. Induction of in vitro human macrophage anti-Mycobacterium tuberculosis activity: requirement for interferon-γ and primed lymphocytes. J. Immunol. 160:4490-4499.
2. Altman, J. D., P. A. H. Moss, P. J. R. Goulder, D. H. Barouch, M. G. McHeyzer-Williams, J. I. Bell, A. J. McMichael, and M. M. Davis. 1996. Phenotypic analysis of antigen-specific T lymphocytes. Science 274:94-96.
3. Barnes, P. F., S. Lu, J. S. Abrams, E. Wang, M. Yamamura, and R. L. Modlin. 1993. Cytokine production at the site of disease in human tuberculosis. Infect. Immun. 61:3482-3489.
4. Barnes, P. F., J. S. Abrams, S. Lu, P. A. Sieling, T. H. Rea, and R. L. Modlin. 1993. Patterns of cytokine production by Mycobacterium-reactive human T-cell clones. Infect. Immun. 61:197-203.
5. Boom, W. H., R. N. Husson, R. A. Young, J. R. David, and W. F. Piessens. 1987. In vivo and in vitro characterization of murine T-cell clones reactive to Mycobacterium tuberculosis. Infect. Immun. 55:2223-2229.
6. Bromberg, J. S., K. D. Chavin, and S. L. Kunkel. 1992. Anti-tumor necrosis factor antibodies suppress cell-mediated immunity in vivo. J. Immunol. 148: 3412-3417.
7. Budd, R. C., J.-C. Cerottini, C. Horvath, C. Bron, T. Pedrazzini, R. C. Howe, and R. H. MacDonald. 1987. Distinction of virgin and memory T lymphocytes. J. Immunol. 138:3120-3129.
8. + cells. J. Immunol. 138:1009-1013.
9. Butz, E. A., and M. J. Bevan. 1998. Massive expansion of antigen-specific CD8+ T cells during an acute virus infection. Immunity 8:167-175.
10. Caruso, A. M., N. Serbina, E. Klein, K. Triebold, B. R. Bloom, and J. L. Flynn. 1999. Mice deficient in CD4 T cells have only transiently diminished levels of IFN-γ, yet succumb to tuberculosis. J. Immunol. 162:5407-5416.
11. Chan, J., Y. Xing, R. Magliozzo, and B. R. Bloom. 1992. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J. Exp. Med. 175:1111-1122.
12. Clemens, D. L., and M. A. Horowitz. 1995. Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited. J. Exp. Med. 181:257-270.
13. Cooper, A. M., D. K. Dalton, T. A. Stewart, J. P. Griffen, D. G. Russell, and I. M. Orme. 1993. Disseminated tuberculosis in IFN-γ gene-disrupted mice. J. Exp. Med. 178:2243-2248.
14. Cooper, A. M., J. E. Callahan, M. Keen, J. T. Beslisle, and I. M. Orme. 1997. Expression of memory immunity in the lung following re-exposure to Mycobacterium tuberculosis. Tubercle Lung Dis. 78:67-73.
15. Cooper, A. M., C. D'Souza, A. A. Frank, and I. M. Orme. 1997. The course of Mycobacterium tuberculosis infection in the lungs of mice lacking expression of either perforin- or granzyme-mediated cytolytic mechanisms. Infect. Immun. 65:1317-1320.
16. De Libero, G., I. Flesch, and S. H. E. Kaufmann. 1988. Mycobacteriareactive Lyt-2+ T cell lines. Eur. J. Immunol. 18:59-66.
17. Denis, M. 1991. Interferon-gamma-treated murine macrophages inhibit growth of tubercle bacilli via the generation of reactive nitrogen intermediates. Cell. Immunol. 132:150-157.
18. Flesch, I. E. A., J. H. Hess, S. Huang, M. Aguet, J. Rothe, H. Bluethmann, and S. H. E. Kaufmann. 1995. Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon γ and tumor necrosis factor α. J. Exp. Med. 181:1615-1621.
19. Flynn, J. L., J. Chan, K. J. Triebold, D. K. Dalton, T. A. Stewart, and B. R. Bloom. 1993. An essential role for interferon-γ in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178:2249-2254.
20. Flynn, J. L., M. M. Goldstein, K. J. Triebold, B. Koller, and B. R. Bloom. 1992. Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc. Natl. Acad. Sci. USA 89:12013-12017.
21. Flynn, J. L., M. M. Goldstein, J. Chan, K. J. Triebold, K. Pfeffer, C. J. Lowenstein, R. Schreiber, T. W. Mak, and B. R. Bloom. 1995. Tumor necrosis factor-α is required in the protective immune response against M. tuberculosis in mice. Immunity 2:561-572.
22. Flynn, K. J., G. T. Belz, J. D. Altman, R. Ahmed, D. L. Woodland, and P. C. Doherty. 1998. Virus-specific CD8+ T cells in primary and secondary influenza pneumonia. Immunity 8:683-691.
23. Garcia, I., Y. Miyazaki, G. Marchal, W. Lesslauer, and P. Vassalli. 1997. High sensitivity of transgenic mice expressing soluble TNFR1 fusion protein to mycobacterial infections: synergistic action of TNF and IFN-gamma in the differentiation of protective granulomas. Eur. J. Immunol. 27:3182-3190.
24. Griffin, J. P., and I. M. Orme. 1994. Evolution of CD4 T-cell subsets following infection of naive and memory immune mice with Mycobacterium tuberculosis. Infect. Immun. 62:1683-1690.
25. Henderson, R. A., S. C. Watkins, and J. L. Flynn. 1997. Activation of human dendritic cells following infection with Mycobacterium tuberculosis. J. Immunol. 159:635-643.
26. Hirsch, C., S., J. J. Ellner, R. Blinkhorn, and Z. Toossi. 1997. In vitro restoration of T cell responses in tuberculosis and augmentation of monocyte effector function against Mycobacterium tuberculosis by natural inhibitors of transforming growth factor beta. Proc. Natl. Acad. Sci. USA 94:3926-3931.
27. Hirsch, C. S., R. Hussain, Z. Toosi, G. Dawood, F. Shahid, and J. J. Ellner. 1996. Cross-modulation by transforming growth factor β in human tuberculosis: suppression of antigen-driven blastogenesis and interferon γ production. Proc. Natl. Acad. Sci. USA 93:3193-3198.
28. Hmama, Z., R. Gabathuler, W. A. Jefferies, G. Dejong, and N. E. Reiner. 1998. Attenuation of HLA-DR expression by mononuclear phagocytes infected with Mycobacterium tuberculosis is related to intracellular sequestration of immature class II heterodimers. J. Immunol. 161:4882-4893.
29. Jouanguy, E., F. Altare, S. Lamhamedi, P. Revy, J.-F. Emile, M. Newport, M. Levin, S. Blanche, E. Seboun, A. Fischer, and J.-L. Casanova. 1996. Interferon-γ receptor deficiency in an infant with fatal bacille Calmette-Guerin infection. N. Engl. J. Med. 335:1956-1961.
30. Kaufmann, S. H., U. Vath, J. E. Thole, J. D. Van Embden, and F. Emmrich. 1987. Enumeration of T cells reactive with Mycobacterium tuberculosis organisms and specific for the recombinant mycobacterial 64-kDa protein. Eur. J. Immunol. 17:351-357.
31. Koga, T., A. Wand-Wurttenberger, J. DeBruyn, M. E. Munk, B. Schoel, and S. H. Kaufmann. 1989. T cells against a bacterial heat shock protein recognize stressed macrophage. Science 245:1112-1115.
32. Kovacsovics-Bankowski, M., and K. L. Rock. 1995. A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science 267:243-246.
33. Lalvani, A., R. Brookes, R. Wilkinson, A. Malin, A. Pathan, P. Andersen, H. Dockrell, G. Pasvol, and A. Hill. 1998. Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 95:270-275.
34. Laochumroonvorapong, P., J. Wang, C.-C. Liu, W. Ye, A. L. Moreira, K. B. Elkon, V. H. Freedman, and G. Kaplan. 1997. Perform, a cytotoxic molecule which mediates cell necrosis, is not required for the early control of mycobacterial infection in mice. Infect. Immun. 65:127-132.
35. Lewisohn, D., M. Alderson, A. Briden, S. Riddell, S. Reed, and K. Grabstein. 1998. Characterization of human CD8+ T cells reactive with Mycobacterium tuberculosis-infected antigen presenting cells. J. Exp. Med. 187:1633-1640.
36. Lyadova, I., V. Yeremeev, K. Majorov, B. Nikonenko, S. Khaidukov, T. Kondratieva, N. Kobets, and A. Apt. 1998. An ex vivo study of T lymphocytes recovered from the lungs of I/St mice infected with and susceptible to Mycobacterium tuberculosis. Infect. Immun. 66:4981-4988.
37. Mazzaccaro, R. J., M. Gedde, E. R. Jensen, H. M. van Santem, H. L. Ploegh, K. L. Rock, and B. R. Bloom. 1996. Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection. Proc. Natl. Acad. Sci. USA 93:11786-11791.
38. McDonough, K. A., Y. Kress, and B. R. Bloom. 1993. Pathogenesis of tuberculosis: interaction of Mycobacterium tuberculosis with macrophages. Infect. Immun. 61:2763-2773.
39. Muller, I., S. Cobbold, H. Waldmann, and S. H. E. Kaufmann. 1987. Impaired resistance to Mycobacterium tuberculosis infection after selective in vivo depletion of L3T4+ and Lyt2+ T cells. Infect. Immun. 55:2037-2041.
40. Murali-Krishna, K., J. D. Altman, M. Suresh, D. J. D. Sourdive, A. J. Zajac, J. D. Miller, J. Slansky, and R. Ahmed. 1998. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity 8:177-187.
41. Newport, M. J., C. Huxley, S. Huston, C. Hawrylowicz, B. Oostra, R. Williamson, and M. Levin. 1996. A mutation in the interferon-γ-receptor gene and susceptibility to mycobacterial infection. N. Engl. J. Med. 335:1941-1949.
42. Orme, I., and F. Collins. 1984. Adoptive protection of the Mycobacterium tuberculosis-infected lung. Cell. Immunol. 84:113-120.
43. Orme, I., E. Miller, A. Roberts, S. Furney, J. Griffen, K. Dobos, D. Chi, B. Rivoire, and P. Brennan. 1992. T lymphocytes mediating protection and cellular cytolysis during the course of Mycobacterium tuberculosis infection. J. Immunol. 148:189-196.
44. Orme, I. M., A. D. Roberts, J. P. Griffen, and J. S. Abrams. 1993. Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection. J. Immunol. 151:518-525.
45. Pfeifer, J. D., M. J. Wick, R. L. Roberts, K. Findlay, and S. J. Normark. 1993. Phagocytic processing of bacterial antigens for class I MHC presentation to T cells. Nature 361:359-362.
46. Pimentel-Muinos, F. X., J. Mazana, and M. Fresno. 1995. Biphasic control of nuclear factor-kappa B activation by the T cell receptor complex: role of tumor necrosis factor alpha. Eur. J. Immunol. 25:179-186.
47. Rich, E. A., C. Cooper, Z. Toossi, M. Leonard, R. Stucky, R. T. Wiblin, and J. J. Ellner. 1991. Requirement for cell-to-cell contact for the immunosuppressive activity of human alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 4:287-294.
48. Roberts, A. D., M. G. Sonnenberg, D. J. Ordway, S. K. Furney, and P. J. Brennan. 1995. Characteristics of protective immunity engendered by vaccination of mice with purified culture filtrate protein antigens of Mycobacterium tuberculosis. Immunology 85:502-508.
49. Russell, D. G., J. Dant, and S. Sturgill-Koszycki. 1996. Mycobacterium avium- and Mycobacterium tuberculosis-containing vacuoles are dynamic, fusion-competent vesicles that are accessible to glycosphingolipids from the host plasmalemma. J. Immunol. 156:4764-4773.
50. Schoel, B., U. Zugel, T. Ruppert, and S. H. Kaufmann. 1994. Elongated peptides, not the predicted nonapeptide stimulate a major histocompatibility complex class I-restricted cytotoxic T lymphocyte clone with specificity for a bacterial heat shock protein. Eur. J. Immunol. 24:3161-3169.
51. Silva, C. L., M. F. Silva, R. C. L. R. Pietro, and D. B. Lowrie. 1994. Protection against tuberculosis by passive transfer with T-cell clones recognizing mycobacterial heat shock protein 65. Immunology 83:341-346.
52. Stenger, S., R. Mazzaccaro, K. Uyemura, S. Cho, P. Barnes, J. Rosat, A. Sette, M. Brenner, S. Porcelli, B. Bloom, and R. Modlin. 1997. Differential effects of cytolytic T cell subsets on intracellular infection. Science 276:1684-1687.
53. Stenger, S., D. A. Hanson, R. Teitelbaum, P. Dewan, K. R. Niazi, C. S. Froelich, T. Ganz, S. Thomauszynski, A. Melian, C. Bogdan, S. A. Porcelli, B. R. Bloom, A. M. Krensky, and R. L. Modlin. 1998. An antimicrobial activity of cytotoxic T cells mediated by granulysin. Science 282:121-125.
54. Tan, J. S., D. H. Canady, W. H. Boom, K. N. Balaji, S. K. Schwander, and E. A. Rich. 1997. Human alveolar T lymphocyte responses to Mycobacterium tuberculosis infection. J. Immunol. 159:290-297.
55. Tascon, R. E., E. Stavropoulos, K. V. Lukacs, and M. J. Colston. 1998. Protection against Mycobacterium tuberculosis infection by CD8 T cells requires production of gamma interferon. Infect. Immun. 66:830-834.
56. Valitutti, S., S. Muller, M. Dessing, and A. Lanzavecchia. 1996. Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J. Exp. Med. 153:1917-1921.
57. Xu, S., A. Cooper, S. Sturgill-Koszycki, T. van Heyningen, D. Chatterjee, I. Orme, P. Allen, and D. G. Russel. 1994. Intracellular trafficking in Mycobacterium tuberculosis- and Mycobacterium avium-infected macrophages. J. Immunol. 153:2568-2578.
58. Zhu, X., N. Venkataprasad, H. S. Thangaraj, M. Hill, M. Singh, J. Ivanyi, and M. H. Vordermeier. 1997. Function and specificity of T cells following nucleic acid vaccination of mice against Mycobacterium tuberculosis infection. J. Immunol. 158:5921-5926.