Determining the origin of the stabilization of DNA by 5-aminopropynylation of pyrimidines

Biochemistry

Volumn 44, Issue 12, 2005, Pages 4710-4719

  Booth, James ^a,d   Brown, Tom ^a   Vadhia, Sunil J ^a   Lack, Oliver ^a   Cummins, W Jon ^b   Trent, John O ^c   Lane, Andrew N ^c  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b GE HEALTHCARE   (United Kingdom)

^c UNIVERSITY OF LOUISVILLE   (United States)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROSTATICS; FREE ENERGY; HYDRATION; IONIC STRENGTH; MELTING; NUCLEAR MAGNETIC RESONANCE; OXYGEN; PHOSPHATES; THERMODYNAMIC STABILITY;

AMINOPROPYNYL MODIFICATION; HYBRIDIZATION; NONELECTROSTATIC COMPONENTS; ULTRA VILOT MELTING;

DNA;

DOUBLE STRANDED DNA; OLIGONUCLEOTIDE; PYRIMIDINE DERIVATIVE;

ARTICLE; CONFORMATION; DNA HYBRIDIZATION; DNA STRUCTURE; HYDRATION; IONIC STRENGTH; MELTING POINT; MOLECULAR DYNAMICS; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN MODIFICATION; THERMODYNAMICS; THERMOSTABILITY;

ALKYNES; DEOXYURIDINE; DNA; DNA, SINGLE-STRANDED; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HETERODUPLEXES; PYRIMIDINES; THERMODYNAMICS;

EID: 15444368861     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047561d     Document Type: Article

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