메뉴 건너뛰기




Volumn 48, Issue 8, 1999, Pages 1535-1542

Glucose regulation of glutaminolysis and its role in insulin secretion

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUTAMATE DEHYDROGENASE; GLUTAMINE; INSULIN; LEUCINE;

EID: 0032806183     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.8.1535     Document Type: Article
Times cited : (93)

References (33)
  • 4
    • 0019133275 scopus 로고
    • L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase
    • Sener A, Malaisse WJ: L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase. Nature 288:187-189, 1980
    • (1980) Nature , vol.288 , pp. 187-189
    • Sener, A.1    Malaisse, W.J.2
  • 5
    • 0017144760 scopus 로고
    • Comparison of the effects of leucines, nonmetabolizable leucine analogues, and other insulin secretagogues on the activity of glutamate dehydrogenase
    • Gylfe E: Comparison of the effects of leucines, nonmetabolizable leucine analogues, and other insulin secretagogues on the activity of glutamate dehydrogenase. Acta Diabetol Lat 13:20-24, 1976
    • (1976) Acta Diabetol Lat , vol.13 , pp. 20-24
    • Gylfe, E.1
  • 6
    • 77955093164 scopus 로고
    • Stimulation of pancreatic islet metabolism and insulin release by a nonmetabolizable amino acid
    • Sener A, Malaisse-Lagae F, Malaisse WJ: Stimulation of pancreatic islet metabolism and insulin release by a nonmetabolizable amino acid. Proc Natl Acad Sci USA 78:5460-5464, 1981
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 5460-5464
    • Sener, A.1    Malaisse-Lagae, F.2    Malaisse, W.J.3
  • 7
    • 0019433688 scopus 로고
    • Insulin release: Reconciliation of the receptor and metabolic hypotheses: Nutrient receptors in islet cells
    • Malaisse WJ, Sener A, Malaisse-Lagae F: Insulin release: reconciliation of the receptor and metabolic hypotheses: nutrient receptors in islet cells. Mol Cell Biochem 37:157-165, 1981
    • (1981) Mol Cell Biochem , vol.37 , pp. 157-165
    • Malaisse, W.J.1    Sener, A.2    Malaisse-Lagae, F.3
  • 8
    • 0020317782 scopus 로고
    • The stimulus-secretion coupling of amino acid-induced insulin release: Influence of a nonmetabolized analog of leucine on the metabolism of glutamine in pancreatic islets
    • Malaisse-Lagae F, Sener A, Garcia-Morales P, Valverde I, Malaisse WJ: The stimulus-secretion coupling of amino acid-induced insulin release: influence of a nonmetabolized analog of leucine on the metabolism of glutamine in pancreatic islets. J Biol Chem 257:3754-3758, 1982
    • (1982) J Biol Chem , vol.257 , pp. 3754-3758
    • Malaisse-Lagae, F.1    Sener, A.2    Garcia-Morales, P.3    Valverde, I.4    Malaisse, W.J.5
  • 9
    • 0021320053 scopus 로고
    • Regulation of insulin secretion by energy metabolism in pancreatic-cell mitochondria: Studies with a nonmetabolizable leucine analogue
    • Panten U, Zielmann S, Langer J, Zunkler BJ, Lenzen S: Regulation of insulin secretion by energy metabolism in pancreatic-cell mitochondria: studies with a nonmetabolizable leucine analogue. Biochem J 219:189-196, 1984
    • (1984) Biochem J , vol.219 , pp. 189-196
    • Panten, U.1    Zielmann, S.2    Langer, J.3    Zunkler, B.J.4    Lenzen, S.5
  • 10
    • 0019268972 scopus 로고
    • The stimulus-secretion coupling of amino acid-induced insulin release: Metabolism and cationic effects of leucine
    • Malaisse WJ, Hutton JC, Carpinelli AR, Herchuelz A, Sener A: The stimulus-secretion coupling of amino acid-induced insulin release: metabolism and cationic effects of leucine. Diabetes 29:431-437, 1980
    • (1980) Diabetes , vol.29 , pp. 431-437
    • Malaisse, W.J.1    Hutton, J.C.2    Carpinelli, A.R.3    Herchuelz, A.4    Sener, A.5
  • 11
    • 0023117765 scopus 로고
    • +] in mouse pancreatic islets, and nutrient-induced insulin secretion
    • +] in mouse pancreatic islets, and nutrient-induced insulin secretion. Biochem J 241:161-167, 1987
    • (1987) Biochem J , vol.241 , pp. 161-167
    • Hedeskov, C.J.1    Capito, K.2    Thams, P.3
  • 13
    • 0018764814 scopus 로고
    • Effect of leucine on the pyridine nucleotide contents of islets and on the insulin-released interactions in vitro with methylene blue, thiol oxidants, and p-chloromercuribenzoate
    • Ammon HP, Hoppe E, Akhtar MS, Niklas H: Effect of leucine on the pyridine nucleotide contents of islets and on the insulin-released interactions in vitro with methylene blue, thiol oxidants, and p-chloromercuribenzoate. Diabetes 28:593-599, 1979
    • (1979) Diabetes , vol.28 , pp. 593-599
    • Ammon, H.P.1    Hoppe, E.2    Akhtar, M.S.3    Niklas, H.4
  • 14
    • 0019454290 scopus 로고
    • The stimulus-secretion coupling of amino acid-induced insulin release: Biosynthetic and secretory responses of rat pancreatic islets to L-leucine and L-glutamine
    • Sener A, Somers G, Devis G, Malaisse WJ: The stimulus-secretion coupling of amino acid-induced insulin release: biosynthetic and secretory responses of rat pancreatic islets to L-leucine and L-glutamine. Diabetologia 21:135-142, 1981
    • (1981) Diabetologia , vol.21 , pp. 135-142
    • Sener, A.1    Somers, G.2    Devis, G.3    Malaisse, W.J.4
  • 15
    • 84880505617 scopus 로고
    • The stimulus-secretion coupling of amino acid-induced insulin release. IV. Ionic response to L-leucine and L-glutamine
    • Malaisse WJ, Carpinelli AR, Lebrun P, Herchuelz A, Sener A: The stimulus-secretion coupling of amino acid-induced insulin release. IV. Ionic response to L-leucine and L-glutamine. Pflugers Arch 391:112-118, 1981
    • (1981) Pflugers Arch , vol.391 , pp. 112-118
    • Malaisse, W.J.1    Carpinelli, A.R.2    Lebrun, P.3    Herchuelz, A.4    Sener, A.5
  • 16
    • 0020359110 scopus 로고
    • Respiration and insulin release in mouse pancreatic islets: Effects of L-leucine and 2-ketoisocaproate in combination with D-glucose and L-glutamine
    • Welsh M, Hellerstrom C, Andersson A: Respiration and insulin release in mouse pancreatic islets: effects of L-leucine and 2-ketoisocaproate in combination with D-glucose and L-glutamine. Biochim Biophys Acta 721:178-184, 1982
    • (1982) Biochim Biophys Acta , vol.721 , pp. 178-184
    • Welsh, M.1    Hellerstrom, C.2    Andersson, A.3
  • 17
    • 0019904523 scopus 로고
    • The stimulus-secretion coupling of amino acid-induced insulin release: Metabolic response of pancreatic islets of L-glutamine and L-leucine
    • Malaisse WJ, Sener A, Malaisse-Lagae F, Welsh M, Matthews DE, Bier DM, Hellerstrom C: The stimulus-secretion coupling of amino acid-induced insulin release: metabolic response of pancreatic islets of L-glutamine and L-leucine. J Biol Chem 257:8731-8737, 1982
    • (1982) J Biol Chem , vol.257 , pp. 8731-8737
    • Malaisse, W.J.1    Sener, A.2    Malaisse-Lagae, F.3    Welsh, M.4    Matthews, D.E.5    Bier, D.M.6    Hellerstrom, C.7
  • 18
    • 0025967980 scopus 로고
    • Glucose regulates leucine-induced insulin release and the expression of the branched-chain ketoacid dehydrogenase E1α subunit gene in pancreatic islets
    • MacDonald MJ, McKenzie DI, Kaysen JH, Walker TM, Moran SM, Fahien LA, Towle HC: Glucose regulates leucine-induced insulin release and the expression of the branched-chain ketoacid dehydrogenase E1α subunit gene in pancreatic islets. J Biol Chem 266:1335-1340, 1991
    • (1991) J Biol Chem , vol.266 , pp. 1335-1340
    • MacDonald, M.J.1    McKenzie, D.I.2    Kaysen, J.H.3    Walker, T.M.4    Moran, S.M.5    Fahien, L.A.6    Towle, H.C.7
  • 19
    • 0028587754 scopus 로고
    • The biochemistry and enzymology of amino acid dehydrogenases
    • Brunhuber NM, Blanchard JS: The biochemistry and enzymology of amino acid dehydrogenases. Crit Rev Biochem Mol Biol 29:415-467, 1994
    • (1994) Crit Rev Biochem Mol Biol , vol.29 , pp. 415-467
    • Brunhuber, N.M.1    Blanchard, J.S.2
  • 21
    • 0028885706 scopus 로고
    • Possible links between glucose-induced changes in the energy state of pancreatic β-cells and insulin release: Unmasking by decreasing a stable pool of adenine nucleotides in mouse islets
    • Detimary P, Jonas JC, Henquin JC: Possible links between glucose-induced changes in the energy state of pancreatic β-cells and insulin release: unmasking by decreasing a stable pool of adenine nucleotides in mouse islets. J Clin Invest 96:1738-1745, 1995
    • (1995) J Clin Invest , vol.96 , pp. 1738-1745
    • Detimary, P.1    Jonas, J.C.2    Henquin, J.C.3
  • 22
    • 0029829055 scopus 로고    scopus 로고
    • Concentration dependence and time course of the effects of glucose on adenine and guanine nucleotides in mouse pancreatic islets
    • Detimary P, Van den Berghe G, Henquin JC: Concentration dependence and time course of the effects of glucose on adenine and guanine nucleotides in mouse pancreatic islets. J Biol Chem 271:20559-20565, 1996
    • (1996) J Biol Chem , vol.271 , pp. 20559-20565
    • Detimary, P.1    Van Den Berghe, G.2    Henquin, J.C.3
  • 23
    • 0030907122 scopus 로고    scopus 로고
    • Tight links between adenine and guanine nucleotide pools in mouse pancreatic islets: A study with mycophenolic acid
    • Detimary P, Xiao C, Henquin JC: Tight links between adenine and guanine nucleotide pools in mouse pancreatic islets: a study with mycophenolic acid. Biochem J 324:467-471, 1997
    • (1997) Biochem J , vol.324 , pp. 467-471
    • Detimary, P.1    Xiao, C.2    Henquin, J.C.3
  • 24
    • 0023695196 scopus 로고
    • Regulation of insulin release by factors that also modify glutamate dehydrogenase
    • Fahien LA, MacDonald MJ, Kmiotek EH, Mertz RI, Fahien CM: Regulation of insulin release by factors that also modify glutamate dehydrogenase. J Biol Chem 263:13610-13614, 1988
    • (1988) J Biol Chem , vol.263 , pp. 13610-13614
    • Fahien, L.A.1    MacDonald, M.J.2    Kmiotek, E.H.3    Mertz, R.I.4    Fahien, C.M.5
  • 25
    • 0020840915 scopus 로고
    • L-leucine methyl ester stimulates insulin secretion and islet glutamate dehydrogenase
    • Knudsen P, Kofod H, Lernmark A, Hedeskov CJ: L-leucine methyl ester stimulates insulin secretion and islet glutamate dehydrogenase. Am J Physiol 245: E338-E346, 1983
    • (1983) Am J Physiol , vol.245
    • Knudsen, P.1    Kofod, H.2    Lernmark, A.3    Hedeskov, C.J.4
  • 26
    • 0020319986 scopus 로고
    • Signal function of metabolism of neutral amino acids and 2-ketoacids for initiation of insulin secretion
    • Lenzen S, Formanek H, Panten U: Signal function of metabolism of neutral amino acids and 2-ketoacids for initiation of insulin secretion. J Biol Chem 257:6631-6633, 1982
    • (1982) J Biol Chem , vol.257 , pp. 6631-6633
    • Lenzen, S.1    Formanek, H.2    Panten, U.3
  • 27
    • 0019814363 scopus 로고
    • The stimulus-secretion coupling of amino acid-induced insulin release: Insulinotropic action of branched-chain amino acids at physiological concentrations of glucose and glutamine
    • Sener A, Malaisse WJ: The stimulus-secretion coupling of amino acid-induced insulin release: insulinotropic action of branched-chain amino acids at physiological concentrations of glucose and glutamine. Eur J Clin Invest 11:455-460, 1981
    • (1981) Eur J Clin Invest , vol.11 , pp. 455-460
    • Sener, A.1    Malaisse, W.J.2
  • 28
    • 0030891622 scopus 로고    scopus 로고
    • Regulation of pancreatic β-cell electrical activity and insulin release by physiological amino acid concentrations
    • Bolea S, Pertusa JA, Martin F, Sanchez-Andres JV, Soria B: Regulation of pancreatic β-cell electrical activity and insulin release by physiological amino acid concentrations. Pflugers Arch 433:699-704, 1997
    • (1997) Pflugers Arch , vol.433 , pp. 699-704
    • Bolea, S.1    Pertusa, J.A.2    Martin, F.3    Sanchez-Andres, J.V.4    Soria, B.5
  • 29
    • 0027443233 scopus 로고
    • Effects of long-chain free fatty acids on glucose-induced insulin secretion in the perfused rat pancreas
    • Mokuda O, Sakamoto Y, Hu H-Y, Kawagoe R, Shimizu N: Effects of long-chain free fatty acids on glucose-induced insulin secretion in the perfused rat pancreas. Horm Metab Res 25:596-597, 1993
    • (1993) Horm Metab Res , vol.25 , pp. 596-597
    • Mokuda, O.1    Sakamoto, Y.2    Hu, H.-Y.3    Kawagoe, R.4    Shimizu, N.5
  • 30
    • 0031716376 scopus 로고    scopus 로고
    • Acute lowering of plasma fatty acids lowers basal insulin secretion in diabetic and nondiabetic subjects
    • Boden G, Chen X, Iqbal N: Acute lowering of plasma fatty acids lowers basal insulin secretion in diabetic and nondiabetic subjects. Diabetes 47:1609-1612, 1998
    • (1998) Diabetes , vol.47 , pp. 1609-1612
    • Boden, G.1    Chen, X.2    Iqbal, N.3
  • 33
    • 0020623001 scopus 로고
    • Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes: A study with the perfused pancreas
    • Giroix MH, Portha B, Kergoat M, Bailbe D, Picon L: Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes: a study with the perfused pancreas. Diabetes 32:445-451, 1983
    • (1983) Diabetes , vol.32 , pp. 445-451
    • Giroix, M.H.1    Portha, B.2    Kergoat, M.3    Bailbe, D.4    Picon, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.