An osmotic-sensitive taurine pool is localized in rat pancreatic islet cells containing glucagon and somatostatin

American Journal of Physiology - Endocrinology and Metabolism

Volumn 281, Issue 6 44-6, 2001, Pages

  Bustamante, J ^a   Lobo, M V T ^a   Alonso, F J ^a   Mukala, N T A ^a   Gine E ^a   Solis J M ^a   Tamarit Rodriguez, J ^b   Martin Del Rio R ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

Amino acid content; Immunocytochemistry; Insulin secretion; Taurine distribution; aminobutyric acid release

Indexed keywords

4 AMINOBUTYRIC ACID; GLUCAGON; SOMATOSTATIN; TAURINE;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GLUCOSE TRANSPORT; HYPOGLYCEMIA; INSULIN RELEASE; MALE; NONHUMAN; OSMOLARITY; OSMOREGULATION; OSMOSIS; PANCREAS ISLET CELL; PRIORITY JOURNAL; RAT;

EID: 0035662149     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2001.281.6.e1275     Document Type: Article

References (63)

1. Evidence for a glutamate receptor of the AMPA subtype which mediates insulin release from rat perfused pancreas
2. Effects of sulphonylureas on the volume-sensitive anion channel in rat pancreatic β-cells
3. Anion fluxes, volume regulation and electrical activity in the mammalian pancreatic β-cell
4. Activation of an anion conductance and β-cell depolarization during hypotonically induced insulin release
5. A volume-activated anion conductance in insulin secreting cells
6. An effect of hyposmolarity on insulin release in vitro
7. A receptors in neuroendocrine gastropancreatic cells
8. A receptor in the rat pancreas
9. Microdetermination of free amino acids in pancreatic islets isolated from obese-hyperglycemic mice
10. Taurine levels and localization in pancreatic islets
11. Immunological approach to the detection of taurine and immunocytochemical results
12. Anisosmotic cell volume regulation: A comparative view
13. Effects of taurine on the insulin secretion of rat fetal islets from dams fed a low-protein diet
14. Stimulatory effects of taurine on insulin secretion by fetal rat islets cultured in vitro
15. Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases
16. B receptors in rat hippocampal CA1 region
17. Taurine-induced synaptic potentiation: Role of calcium and interaction with LTP
18. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: Effects of taurine supplementation
19. Taurine induces a long-lasting increase of synaptic efficacy and axon excitability in the hippocampus
20. Immunohistochemical colocalization of GABA and insulin in β-cells of rat islet
21. Glucose modulates γ-aminobutyric acid release from the pancreatic βTC6 cell line
22. Gamma-aminobutyric acid in peripheral tissue, with emphasis on the endocrine pancreas. Presence in two species and reduction by streptozotocin
23. GABA in peripheral tissues: Presence and actions in endocrine pancreatic function
24. The influence of γ-aminobutyric acid on hormone release by the mouse and rat endocrine pancreas
25. Supplemental taurine in diabetic rats: Effects on plasma glucose and triglycerides
26. Volume-sensitive amino acid efflux from a pancreatic β-cell line
27. Changes of free amino acids in pancreatic β-cells after starvation and substrate deprivation
28. Coated charcoal immunoassay of insulin
29. Preparation of iodine-131 labelled human growth hormone of high specific activity
30. Physiological actions of taurine
31. An ATP-sensitive Cl channel current that is activated by cell swelling, cAMP and glyburide in insulinsecreting cells
32. Hypoglycemic properties of taurine: Not mediated by enhanced insulin release
33. Method for the isolation of intact islets of Langerhans from the rat pancreas
34. Potentiation of the actions of insulin by taurine
35. Immunohistochemical localization of taurine in the male reproductive organs of the rat
36. Immunocytochemical visualization of taurine: Neuronal localization in the rat cerebellum
37. Immunocyto-chemical localization of taurine: Methodological aspects
38. Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis
39. Taurine binding to the purified insulin receptor
40. Pancreatic islet glucose metabolism and regulation of insulin secretion
41. Glutamate production in islets of Langerhans: Properties of phosphate-activated glutaminase
42. GABA production in rat islets of Langerhans
43. Glucose-induced swelling in rat pancreatic β-cells
44. α-soluble N-ethylmaleimide-sensitive factor attachment protein is expressed in pancreatic β cells and functions in insulin but not γ-aminobutyric acid secretion
45. Neuronal-glial exchange of taurine during hypo-osmotic stress: A combined immunocytochemical and biochemical analysis in rat cerebellar cortex
46. Localization and function of GABA in the pancreatic islets
47. Inhibitory actions of taurocyamine, hypotaurine, homotaurine, taurine and GABA on spike discharges of Purkinje cells, and localization of sensitive sites, in guinea pig cerebellar slices
48. 2+ sequestration by taurine
49. Taurine and mechanisms of cell volume regulation
50. GABA and pancreatic B-cells: Colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion
51. A-receptor chloride channels
52. Neurotransmitters and their receptors in the islets of Langerhans of the pancreas
53. Electrophysiological and electropharmacological actions of taurine on cardiac cells
54. 2+ currents in young embryonic chick cardiomyocytes
55. Increased expression of GAD65 and GABA in pancreatic β-cells impairs first-phase insulin secretion
56. Nutrient regulation of gamma-aminobutyric acid release from islet cells
57. Does taurine act as an osmoregulatory substance in the rat brain?
58. Taurine in development
59. A γ-aminobutyric acid transporter driven by a proton pump is present in synaptic-like microvesicles of pancreatic β cells
60. A role for synaptic vesicles in non-neuronal cells: Clues from pancreatic cells and from chromaffin cells
61. Protective actions of taurine against streptozotocin-induced hyperglycemia
62. Streptozotocin-induced elevation of pancreatic taurine content and suppressive effect of taurine on insulin secretion
63. Differential expression of glutamate receptors subtypes in rat pancreatic islets