-
1
-
-
0034673972
-
Transforming growth factor-β signaling mediators and modulators
-
Zimmerman, C.M. & Padgett, R.W. (2000) Transforming growth factor-β signaling mediators and modulators. Gene 249, 17-30.
-
(2000)
Gene
, vol.249
, pp. 17-30
-
-
Zimmerman, C.M.1
Padgett, R.W.2
-
2
-
-
0031685620
-
TGF-β signal transduction
-
Massagué, J. (1998) TGF-β signal transduction. Annu. Rev. Biochem. 67, 753-791.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 753-791
-
-
Massagué, J.1
-
3
-
-
0032763469
-
Specificity, diversity, and regulation in TGF-β superfamily signaling
-
Piek, E., Heldin, C.-H. & ten Dijke, P. (1999) Specificity, diversity, and regulation in TGF-β superfamily signaling. FASEB J. 13, 2105-2124.
-
(1999)
FASEB J.
, vol.13
, pp. 2105-2124
-
-
Piek, E.1
Heldin, C.-H.2
Ten Dijke, P.3
-
4
-
-
0032403377
-
Glial cell line-derived neurotrophic factor requires transforming growth factor-β for exerting its full neurotrophic potential on peripheral and CNS neurons
-
Krieglstein, K., Henheik, P., Farkas, L., Jaszai, J., Galter, D., Krohn, K. & Unsicker, K. (1998) Glial cell line-derived neurotrophic factor requires transforming growth factor-β for exerting its full neurotrophic potential on peripheral and CNS neurons. J. Neurosci. 18, 9822-9834.
-
(1998)
J. Neurosci.
, vol.18
, pp. 9822-9834
-
-
Krieglstein, K.1
Henheik, P.2
Farkas, L.3
Jaszai, J.4
Galter, D.5
Krohn, K.6
Unsicker, K.7
-
5
-
-
0033773180
-
The transforming growth factor-βs: Structure, signaling, and roles in nervous system development and functions
-
Böttner, M., Krieglstein, K. & Unsicker, K. (2000) The transforming growth factor-βs: Structure, signaling, and roles in nervous system development and functions. J. Neurochem. 75, 2227-2240.
-
(2000)
J. Neurochem.
, vol.75
, pp. 2227-2240
-
-
Böttner, M.1
Krieglstein, K.2
Unsicker, K.3
-
6
-
-
0029944441
-
Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors
-
ten Dijke, P., Miyazono, K. & Heldin, C.-H. (1996) Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Curr. Opin. Cell Biol. 8, 139-145.
-
(1996)
Curr. Opin. Cell Biol.
, vol.8
, pp. 139-145
-
-
Ten Dijke, P.1
Miyazono, K.2
Heldin, C.-H.3
-
7
-
-
0026496172
-
TGF-βsignals through a heteromeric protein kinase receptor complex
-
Wrana, J.L., Attisano, L., Carcamo, J., Zentella, A., Doody, J., Laiho, M., Wang, X.F. & Massagué, J. (1992) TGF-βsignals through a heteromeric protein kinase receptor complex. Cell 71, 1003-1014.
-
(1992)
Cell
, vol.71
, pp. 1003-1014
-
-
Wrana, J.L.1
Attisano, L.2
Carcamo, J.3
Zentella, A.4
Doody, J.5
Laiho, M.6
Wang, X.F.7
Massagué, J.8
-
8
-
-
0026537831
-
Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase
-
Lin, H.Y., Wang, X.F., Ng-Eaton, E., Weinberg, R.A. & Lodish, H.F. (1992) Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase. Cell 68, 775-785.
-
(1992)
Cell
, vol.68
, pp. 775-785
-
-
Lin, H.Y.1
Wang, X.F.2
Ng-Eaton, E.3
Weinberg, R.A.4
Lodish, H.F.5
-
9
-
-
0035254335
-
Type III TGF-β receptor-independent signalling of TGF-β2 via TβRII- B, an alternatively spliced TGF-β type II receptor
-
Rotzer, D., Roth, M., Lutz, M., Lindemann, D., Sebald, W. & Knaus, P. (2001) Type III TGF-β receptor-independent signalling of TGF-β2 via TβRII-B, an alternatively spliced TGF-β type II receptor. EMBO J. 20, 480-490.
-
(2001)
EMBO J.
, vol.20
, pp. 480-490
-
-
Rotzer, D.1
Roth, M.2
Lutz, M.3
Lindemann, D.4
Sebald, W.5
Knaus, P.6
-
10
-
-
0028170226
-
Mechanism of activation of the TGF-β receptor
-
Wrana, J.L., Attisano, L., Wieser, R., Ventura, F. & Massagué, J. (1994) Mechanism of activation of the TGF-β receptor. Nature 370, 341-347.
-
(1994)
Nature
, vol.370
, pp. 341-347
-
-
Wrana, J.L.1
Attisano, L.2
Wieser, R.3
Ventura, F.4
Massagué, J.5
-
11
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through Smad proteins
-
Heldin, C.-H., Miyazono, K. & ten Dijke, P. (1997) TGF-β signalling from cell membrane to nucleus through Smad proteins. Nature 390, 465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.-H.1
Miyazono, K.2
Ten Dijke, P.3
-
12
-
-
0034654497
-
Controlling TGF-β signaling
-
Massagué, J. & Chen, Y.G. (2000) Controlling TGF-β signaling. Genes Dev. 14, 627-644.
-
(2000)
Genes Dev.
, vol.14
, pp. 627-644
-
-
Massagué, J.1
Chen, Y.G.2
-
13
-
-
0029834067
-
Partnership between DPC4 and Smad proteins in TGF-β signalling pathways
-
Lagna, G., Hata, A., Hemmati-Brivanlou, A. & Massagué, J. (1996) Partnership between DPC4 and Smad proteins in TGF-β signalling pathways. Nature 383, 832-836.
-
(1996)
Nature
, vol.383
, pp. 832-836
-
-
Lagna, G.1
Hata, A.2
Hemmati-Brivanlou, A.3
Massagué, J.4
-
14
-
-
0033168915
-
Regulation of Smad signalling by protein associations and signalling crosstalk
-
Zhang, Y. & Derynck, R. (1999) Regulation of Smad signalling by protein associations and signalling crosstalk. Trends Cell Biol. 9, 274-279.
-
(1999)
Trends Cell Biol.
, vol.9
, pp. 274-279
-
-
Zhang, Y.1
Derynck, R.2
-
15
-
-
0034533657
-
Signaling of transforming growth factor-β family members through Smad proteins
-
Itoh, S., Itoh, F., Goumas, M.-J. & ten Dijke, P. (2000) Signaling of transforming growth factor-β family members through Smad proteins. Eur. J. Biochem. 267, 6954-6967.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 6954-6967
-
-
Itoh, S.1
Itoh, F.2
Goumas, M.-J.3
Ten Dijke, P.4
-
16
-
-
0033602186
-
A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3
-
Dennler, S., Huet, S. & Gauthier, J.M. (1999) A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3. Oncogene 18, 1643-1648.
-
(1999)
Oncogene
, vol.18
, pp. 1643-1648
-
-
Dennler, S.1
Huet, S.2
Gauthier, J.M.3
-
17
-
-
0033534573
-
Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3
-
Yagi, K., Goto, D., Hamamoto, T., Takenoshita, S., Kato, M. & Miyazono, K. (1999) Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3. J. Biol. Chem. 274, 703-709.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 703-709
-
-
Yagi, K.1
Goto, D.2
Hamamoto, T.3
Takenoshita, S.4
Kato, M.5
Miyazono, K.6
-
18
-
-
0033956131
-
Signaling inputs converge on nuclear effectors in TGF-β signaling
-
ten Dijke, P., Miyazono, K. & Heldin, C.-H. (2000) Signaling inputs converge on nuclear effectors in TGF-β signaling. Trends Biochem. Sci. 25, 64-70.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 64-70
-
-
Ten Dijke, P.1
Miyazono, K.2
Heldin, C.-H.3
-
19
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGF-β receptor and functions as an antagonist of TGF-β signaling
-
Hayashi, H., Abdollah, S., Qiu, Y., Cai, J., Xu, Y.Y., Grinnell, B.W., Richardson, M.A., Topper, J.N., Gimbrone, M.A. Jr, Wrana, J.L. & Falb, D. (1997) The MAD-related protein Smad7 associates with the TGF-β receptor and functions as an antagonist of TGF-β signaling. Cell 89, 1165-1173.
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.3
Cai, J.4
Xu, Y.Y.5
Grinnell, B.W.6
Richardson, M.A.7
Topper, J.N.8
Gimbrone Jr., M.A.9
Wrana, J.L.10
Falb, D.11
-
20
-
-
0030611757
-
Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signalling
-
Nakao, A., Afrakhte, M., Morén, A., Nakayama, T., Christian, J.L., Heuchel, R., Itoh, S., Kawabata, M., Heldin, N.E., Heldin, C.-H. & ten Dijke, P. (1997) Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signalling. Nature 389, 631-635.
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Morén, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
Itoh, S.7
Kawabata, M.8
Heldin, N.E.9
Heldin, C.-H.10
Ten Dijke, P.11
-
21
-
-
0035918274
-
Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation
-
Ebisawa, T., Fukuchi, M., Murakami, T.C., Tanaka, K., Imamura, T. & Miyazono, K. (2001) Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation. J. Biol. Chem. 276, 12477-12480.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12477-12480
-
-
Ebisawa, T.1
Fukuchi, M.2
Murakami, T.C.3
Tanaka, K.4
Imamura, T.5
Miyazono, K.6
-
22
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-β receptor for degradation
-
Kavsak, P., Rasmussen, R.K., Causing, C.G., Bonni, S., Zhu, H., Thomsen, G.H. & Wrana, J.L. (2000) Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-β receptor for degradation. Mol. Cell 6, 1365-1375.
-
(2000)
Mol. Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
Wrana, J.L.7
-
23
-
-
0032547272
-
Induction of inhibitory Smad6 and Smad7 mRNA by TGF-β family members
-
Afrakhte, M., Morén, A., Jossan, S., Itoh, S., Sampath, K., Westermark, B., Heldin, C.-H., Heldin, N.E. & ten Dijke, P. (1998) Induction of inhibitory Smad6 and Smad7 mRNA by TGF-β family members. Biochem. Biophys. Res. Commun. 249, 505-511.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.249
, pp. 505-511
-
-
Afrakhte, M.1
Morén, A.2
Jossan, S.3
Itoh, S.4
Sampath, K.5
Westermark, B.6
Heldin, C.-H.7
Heldin, N.E.8
Ten Dijke, P.9
-
24
-
-
0033604518
-
Neurotrophin signaling via Trks and p75
-
Friedman, W.J. & Greene, L.A. (1999) Neurotrophin signaling via Trks and p75. Exp. Cell Res. 253, 131-142.
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 131-142
-
-
Friedman, W.J.1
Greene, L.A.2
-
25
-
-
0034044227
-
Neurotrophin signal transduction in the nervous system
-
Kaplan, D.R. & Miller, F.D. (2000) Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 10, 381-391.
-
(2000)
Curr. Opin. Neurobiol.
, vol.10
, pp. 381-391
-
-
Kaplan, D.R.1
Miller, F.D.2
-
27
-
-
0034574298
-
How cells read TGF-β signals
-
Massagué, J. (2000) How cells read TGF-β signals. Nat. Rev. Mol. Cell. Biol. 1, 169-178.
-
(2000)
Nat. Rev. Mol. Cell. Biol.
, vol.1
, pp. 169-178
-
-
Massagué, J.1
-
28
-
-
0030773834
-
Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1
-
Kretzschmar, M., Doody, J. & Massagué, J. (1997) Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1. Nature 389, 618-622.
-
(1997)
Nature
, vol.389
, pp. 618-622
-
-
Kretzschmar, M.1
Doody, J.2
Massagué, J.3
-
29
-
-
0033601179
-
Interdependent Smad and JNK signaling in transforming growth factor-β-mediated transcription
-
Engel, M.E., McDonnell, M.A., Law, B.K. & Moses, H.L. (1999) Interdependent Smad and JNK signaling in transforming growth factor-β-mediated transcription. J. Biol. Chem. 274, 37413-37420.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37413-37420
-
-
Engel, M.E.1
McDonnell, M.A.2
Law, B.K.3
Moses, H.L.4
-
30
-
-
0035286516
-
Regulation of Smad signaling by protein kinase C
-
Yakymovych, I., ten Dijke, P., Heldin, C.-H. & Souchelnytskyi, S. (2001) Regulation of Smad signaling by protein kinase C. FASEB J. 15, 553-555.
-
(2001)
FASEB J.
, vol.15
, pp. 553-555
-
-
Yakymovych, I.1
Ten Dijke, P.2
Heldin, C.-H.3
Souchelnytskyi, S.4
-
31
-
-
0030768644
-
TGF-β receptor-mediated signalling through Smad2, Smad3 and Smad4
-
Nakao, A., Imamura, T., Souchelnytskyi, S., Kawabata, M., Ishisaki, A., Oeda, E., Tamaki, K., Hanai, J., Heldin, C.-H., Miyazono, K. & ten Dijke, P. (1997) TGF-β receptor-mediated signalling through Smad2, Smad3 and Smad4. EMBO J. 16, 5353-5362.
-
(1997)
EMBO J.
, vol.16
, pp. 5353-5362
-
-
Nakao, A.1
Imamura, T.2
Souchelnytskyi, S.3
Kawabata, M.4
Ishisaki, A.5
Oeda, E.6
Tamaki, K.7
Hanai, J.8
Heldin, C.-H.9
Miyazono, K.10
Ten Dijke, P.11
-
32
-
-
0033531948
-
Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- And activin-mediated growth arrest and apoptosis in B cells
-
Ishisaki, A., Yamato, K., Hashimoto, S., Nakao, A., Tamaki, K., Nonaka, K., ten Dijke, P., Sugino, H. & Nishihara, T. (1999) Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein-and activin-mediated growth arrest and apoptosis in B cells. J. Biol. Chem. 274, 13637-13642.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13637-13642
-
-
Ishisaki, A.1
Yamato, K.2
Hashimoto, S.3
Nakao, A.4
Tamaki, K.5
Nonaka, K.6
Ten Dijke, P.7
Sugino, H.8
Nishihara, T.9
-
33
-
-
0035958625
-
Transforming growth factor-β signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts
-
Dooley, S., Delvoux, B., Streckert, M., Bonzel, L., Stopa, M., ten Dijke, P. & Gressner, A.M. (2001) Transforming growth factor-β signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts. FEBS Lett. 502, 4-10.
-
(2001)
FEBS Lett.
, vol.502
, pp. 4-10
-
-
Dooley, S.1
Delvoux, B.2
Streckert, M.3
Bonzel, L.4
Stopa, M.5
Ten Dijke, P.6
Gressner, A.M.7
-
34
-
-
0030613262
-
Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-β signaling
-
Souchelnytskyi, S., Tamaki, K., Engstrom, U., Wernstedt, C., ten Dijke, P. & Heldin, C.-H. (1997) Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-β signaling. J. Biol. Chem. 272, 28107-28115.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28107-28115
-
-
Souchelnytskyi, S.1
Tamaki, K.2
Engstrom, U.3
Wernstedt, C.4
Ten Dijke, P.5
Heldin, C.-H.6
-
35
-
-
0030922980
-
Characterization of functional domains within Smad4/DPC4
-
de Caestecker, M.P., Hemmati, P., Larisch-Bloch, S., Ajmera, R., Roberts, A.B. & Lechleider, R.J. (1997) Characterization of functional domains within Smad4/DPC4. J. Biol. Chem. 272, 13690-13696.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13690-13696
-
-
De Caestecker, M.P.1
Hemmati, P.2
Larisch-Bloch, S.3
Ajmera, R.4
Roberts, A.B.5
Lechleider, R.J.6
-
36
-
-
0345704610
-
Establishment of a non-adrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
-
Greene, L.A. & Tischler, A. (1976) Establishment of a non-adrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl Acad. Sci. USA 73, 2424-2428.
-
(1976)
Proc. Natl Acad. Sci. USA
, vol.73
, pp. 2424-2428
-
-
Greene, L.A.1
Tischler, A.2
-
37
-
-
0027236954
-
Production of high-liter helper-free retroviruses by transient transfection
-
Pear, W.S., Nolan, G.P., Scott, M.L. & Baltimore, D. (1993) Production of high-liter helper-free retroviruses by transient transfection. Proc. Natl Acad. Sci. USA 90, 8392-8396.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 8392-8396
-
-
Pear, W.S.1
Nolan, G.P.2
Scott, M.L.3
Baltimore, D.4
-
38
-
-
0028328817
-
An assay for transforming growth factor-β using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct
-
Abe, M., Harpel, J.G., Metz, C.N., Nunes, I., Loskutoff, D.J. & Rifkin, D.B. (1994) An assay for transforming growth factor-β using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal. Biochem. 216, 276-284.
-
(1994)
Anal. Biochem.
, vol.216
, pp. 276-284
-
-
Abe, M.1
Harpel, J.G.2
Metz, C.N.3
Nunes, I.4
Loskutoff, D.J.5
Rifkin, D.B.6
-
39
-
-
0030886204
-
Transforming growth factor-β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells
-
Liu, X., Sun, Y., Constantinescu, S.N., Karam, E., Weinberg, R.A. & Lodish, H.F. (1997) Transforming growth factor-β-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc. Natl Acad. Sci. USA 94, 10669-10674.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 10669-10674
-
-
Liu, X.1
Sun, Y.2
Constantinescu, S.N.3
Karam, E.4
Weinberg, R.A.5
Lodish, H.F.6
-
40
-
-
0029763587
-
Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice
-
Kistner, A., Gossen, M., Zimmermann, F., Jerecic, J., Ullmer, C., Lubbert, H. & Bujard, H. (1996) Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc. Natl Acad. Sci. USA 93, 10933-10938.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 10933-10938
-
-
Kistner, A.1
Gossen, M.2
Zimmermann, F.3
Jerecic, J.4
Ullmer, C.5
Lubbert, H.6
Bujard, H.7
-
41
-
-
0032516862
-
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic protein-inducible enhancer
-
Jonk, L.J., Itoh, S., Heldin, C.-H., ten Dijke, P. & Kruijer, W. (1998) Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic protein-inducible enhancer. J. Biol. Chem. 273, 21145-21152.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21145-21152
-
-
Jonk, L.J.1
Itoh, S.2
Heldin, C.-H.3
Ten Dijke, P.4
Kruijer, W.5
-
42
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
Dennler, S., Itoh, S., Vivien, D., ten Dijke, P., Huet, S. & Gauthier, J.M. (1998) Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17, 3091-3100.
-
(1998)
EMBO J.
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
Ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
43
-
-
0030697971
-
Tumor suppressor Smad4 is a transforming growth factor-β-inducible DNa binding protein
-
Yingling, J.M., Datto, M.B., Wong, C., Frederick, J.P., Liberati, N.T. & Wang, X.F. (1997) Tumor suppressor Smad4 is a transforming growth factor-β-inducible DNA binding protein. Mol. Cell. Biol. 17, 7019-7028.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 7019-7028
-
-
Yingling, J.M.1
Datto, M.B.2
Wong, C.3
Frederick, J.P.4
Liberati, N.T.5
Wang, X.F.6
-
44
-
-
0029815781
-
Distinct modulatory actions of TGF-β and LIF on neurotrophin- mediated survival of developing sensory neurons
-
Krieglstein, K. & Unsicker, K. (1996) Distinct modulatory actions of TGF-β and LIF on neurotrophin-mediated survival of developing sensory neurons. Neurochem. Res. 21, 843-850.
-
(1996)
Neurochem. Res.
, vol.21
, pp. 843-850
-
-
Krieglstein, K.1
Unsicker, K.2
-
45
-
-
0034105456
-
Co-activation of TGF-β and cytokine signaling pathways are required for neurotrophic functions
-
Unsicker, K. & Krieglstein, K. (2000) Co-activation of TGF-β and cytokine signaling pathways are required for neurotrophic functions. Cytokine Growth Factor Rev. 11, 97-102.
-
(2000)
Cytokine Growth Factor Rev.
, vol.11
, pp. 97-102
-
-
Unsicker, K.1
Krieglstein, K.2
-
46
-
-
0027965988
-
Nerve growth factor induces transcription of transforming growth factor-β1 through a specific promoter element in PC12 cells
-
Kim, S.J., Park, K., Rudkin, B.B., Dey, B.R., Sporn, M.B. & Roberts, A.B. (1994) Nerve growth factor induces transcription of transforming growth factor-β1 through a specific promoter element in PC12 cells. J. Biol. Chem. 269, 3739-3744.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 3739-3744
-
-
Kim, S.J.1
Park, K.2
Rudkin, B.B.3
Dey, B.R.4
Sporn, M.B.5
Roberts, A.B.6
-
47
-
-
0024281442
-
Absence of TGF-β receptors and growth inhibitory responses in retinoblastoma cells
-
Kimchi, A., Wang, X.-F., Weinberg, R.A., Cheifetz, S. & Massagué, J. (1988) Absence of TGF-β receptors and growth inhibitory responses in retinoblastoma cells. Science 240, 196-199.
-
(1988)
Science
, vol.240
, pp. 196-199
-
-
Kimchi, A.1
Wang, X.-F.2
Weinberg, R.A.3
Cheifetz, S.4
Massagué, J.5
-
48
-
-
0035895912
-
The orphan receptor serine/threonine kinase alk7 signals arrest of proliferation and morphological differentiation in a neuronal cell line
-
Jörnvall, H., Blokzijl, A., Dijke, P. & Ibanez, C.F. (2001) The orphan receptor serine/threonine kinase alk7 signals arrest of proliferation and morphological differentiation in a neuronal cell line. J. Biol. Chem. 276, 5140-5146.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5140-5146
-
-
Jörnvall, H.1
Blokzijl, A.2
Dijke, P.3
Ibanez, C.F.4
-
49
-
-
0030613249
-
TβRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling
-
Abdollah, S., Macias-Silva, M., Tsukazaki, T., Hayashi, H., Attisano, L. & Wrana, J.L. (1997) TβRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling. J. Biol. Chem. 272, 27678-27685.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27678-27685
-
-
Abdollah, S.1
Macias-Silva, M.2
Tsukazaki, T.3
Hayashi, H.4
Attisano, L.5
Wrana, J.L.6
-
50
-
-
0034695590
-
The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain
-
de Caestecker, M.P., Yahata, T., Wang, D., Parks, W.T., Huang, S., Hill, C.S., Shioda, T., Roberts, A.B. & Lechleider, R.J. (2000) The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain. J. Biol. Chem. 275, 2115-2122.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2115-2122
-
-
De Caestecker, M.P.1
Yahata, T.2
Wang, D.3
Parks, W.T.4
Huang, S.5
Hill, C.S.6
Shioda, T.7
Roberts, A.B.8
Lechleider, R.J.9
-
51
-
-
0036888335
-
Integration of the TGF-β pathway into the cellular signalling network
-
Lutz, M. & Knaus, P. (2002) Integration of the TGF-β pathway into the cellular signalling network. Cell. Signal. 14, 977-988.
-
(2002)
Cell. Signal.
, vol.14
, pp. 977-988
-
-
Lutz, M.1
Knaus, P.2
-
52
-
-
0033605562
-
ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-β signaling
-
Sano, Y., Harada, J., Tashiro, S., Gotoh-Mandeville, R., Maekawa, T. & Ishii, S. (1999) ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-β signaling. J. Biol. Chem. 274, 8949-8957.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8949-8957
-
-
Sano, Y.1
Harada, J.2
Tashiro, S.3
Gotoh-Mandeville, R.4
Maekawa, T.5
Ishii, S.6
-
53
-
-
0030946194
-
TGF-β latency: Biological significance and mechanisms of activation
-
Gleizes, P.E., Munger, J.S., Nunes, I., Harpel, J.G., Mazzieri, R., Noguera, I. & Rifkin, D.B. (1997) TGF-β latency: biological significance and mechanisms of activation. Stem Cells 15, 190-197.
-
(1997)
Stem Cells
, vol.15
, pp. 190-197
-
-
Gleizes, P.E.1
Munger, J.S.2
Nunes, I.3
Harpel, J.G.4
Mazzieri, R.5
Noguera, I.6
Rifkin, D.B.7
-
54
-
-
0033605559
-
MEKK-1, a component of the stress (stress-activated protein kinase/c- Jun N-terminal kinase) pathway, can selectively activate Smad2-mediated transcriptional activation in endothelial cells
-
Brown, J.D., DiChiara, M.R., Anderson, K.R., Gimbrone, M.A. Jr & Topper, J.N. (1999) MEKK-1, a component of the stress (stress-activated protein kinase/c-Jun N-terminal kinase) pathway, can selectively activate Smad2-mediated transcriptional activation in endothelial cells. J. Biol. Chem. 274, 8797-8805.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8797-8805
-
-
Brown, J.D.1
Dichiara, M.R.2
Anderson, K.R.3
Gimbrone Jr., M.A.4
Topper, J.N.5
-
55
-
-
0035123060
-
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
-
Chacko, B.M., Qin, B., Correia, J.J., Lam, S.S., de Caestecker, M.P. & Lin, K. (2001) The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization. Nat. Struct. Biol. 8, 248-253.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 248-253
-
-
Chacko, B.M.1
Qin, B.2
Correia, J.J.3
Lam, S.S.4
De Caestecker, M.P.5
Lin, K.6
-
56
-
-
0035814804
-
Sedimentation studies reveal a direct role of phosphorylation in Smad3: Smad4 homo- and hetero-trimerization
-
Correia, J.J., Chacko, B.M., Lam, S.S. & Lin, K. (2001) Sedimentation studies reveal a direct role of phosphorylation in Smad3: Smad4 homo-and hetero-trimerization. Biochemistry 40, 1473-1482.
-
(2001)
Biochemistry
, vol.40
, pp. 1473-1482
-
-
Correia, J.J.1
Chacko, B.M.2
Lam, S.S.3
Lin, K.4
-
57
-
-
0034460336
-
Transforming growth factor-β-independent shuttling of Smad4 between the cytoplasm and nucleus
-
Pierreux, C.E., Nicolas, F.J. & Hill, C.S. (2000) Transforming growth factor-β-independent shuttling of Smad4 between the cytoplasm and nucleus. Mol. Cell. Biol. 20, 9041-9054.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 9041-9054
-
-
Pierreux, C.E.1
Nicolas, F.J.2
Hill, C.S.3
-
58
-
-
0032428684
-
SARA, a FYVE domain protein that recruits Smad2 to the TGF-β receptor
-
Tsukazaki, T., Chiang, T.A., Davison, A.F., Attisano, L. & Wrana, J.L. (1998) SARA, a FYVE domain protein that recruits Smad2 to the TGF-β receptor. Cell 95, 779-791.
-
(1998)
Cell
, vol.95
, pp. 779-791
-
-
Tsukazaki, T.1
Chiang, T.A.2
Davison, A.F.3
Attisano, L.4
Wrana, J.L.5
-
59
-
-
0034253480
-
The nuclear import function of Smad2 is masked by SARA and unmasked by TGF-β-dependent phosphorylation
-
Xu, L., Chen, Y.G. & Massagué, J. (2000) The nuclear import function of Smad2 is masked by SARA and unmasked by TGF-β-dependent phosphorylation. Nat. Cell Biol. 2, 559-562.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 559-562
-
-
Xu, L.1
Chen, Y.G.2
Massagué, J.3
-
60
-
-
0033969934
-
Microtubule binding to Smads may regulate TGF-β activity
-
Dong, C., Li, Z., Alvarez, R., Feng, X.H. & Goldschmidt-Clermont, P.J. (2000) Microtubule binding to Smads may regulate TGF-β activity. Mol. Cell. 5, 27-34.
-
(2000)
Mol. Cell.
, vol.5
, pp. 27-34
-
-
Dong, C.1
Li, Z.2
Alvarez, R.3
Feng, X.H.4
Goldschmidt-Clermont, P.J.5
-
61
-
-
0035207033
-
Inhibition of BMP2-induced, TAK1 kinase-mediated neunte outgrowth by Smad6 and Smad7
-
Yanagisawa, M., Nakashima, K., Takeda, K., Ochiai, W., Takizawa, T., Ueno, M., Takizawa, M., Shibuya, H. & Taga, T. (2001) Inhibition of BMP2-induced, TAK1 kinase-mediated neunte outgrowth by Smad6 and Smad7. Genes Cells 6, 1091-1099.
-
(2001)
Genes Cells
, vol.6
, pp. 1091-1099
-
-
Yanagisawa, M.1
Nakashima, K.2
Takeda, K.3
Ochiai, W.4
Takizawa, T.5
Ueno, M.6
Takizawa, M.7
Shibuya, H.8
Taga, T.9
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