MEKK-1, a component of the stress (stress-activated protein kinase/c- jun N-terminal kinase) pathway, can selectively activate Smad2-mediated transcriptional activation in endothelial cells

Journal of Biological Chemistry

Volumn 274, Issue 13, 1999, Pages 8797-8805

  Brown, Jonathan D ^a   DiChiara, Maria R ^b   Anderson, Keith R ^a   Gimbrone Jr , Michael A ^a,b,c   Topper, James N ^b,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ANALYSIS; GENE OVEREXPRESSION; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANIMALS; CATTLE; CELLS, CULTURED; DNA-BINDING PROTEINS; ENDOTHELIUM, VASCULAR; GENES, REPORTER; IMMUNOHISTOCHEMISTRY; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 1; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; EUKARYOTA;

EID: 0033605559     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.13.8797     Document Type: Article

References (34)

1. Baker, J. C., and Harland, R. M. (1997) Curr. Opin. Genet. & Dev. 7, 467-473
2. Massague, J. (1996) Cell 85, 947-950
3. Wrana, J. L. (1998) Miner. Electrolyte Metab. 24, 120-130
4. Waldrip, W. R., Bikoff, E. K., Hoodless, P. A., Wrana, J. L., and Robertson, E. J. (1998) Cell 92, 797-808
5. Zhou, S., Buckhaults, P., Zawel, L., Bunz, F., Riggins, G., Le Dai, J., Kern, S. E., Kinzler, K. W., and Vogelstein, B. (1998) Prof. Natl. Acad. Sci. U. S. A. 95, 2412-2416
6. Kretzschmar, M., Doody, J., and Massague, J. (1997) Nature 389, 618-622
7. Chung, K. Y., Agarwal, A., Uitto, J., and Mauviel, A. (1996) J. Biol. Chem. 271, 3272-3278
8. Zhang, Y., Feng, X. H., and Derynck, R. (1998) Nature 394, 909-913
9. de Caestecker, M. P., Parks, W. T., Frank, C. J., Castagnino, P., Bottaro, D. P., Roberts, A. B., and Lechleider, R. J. (1998) Genes Dev. 12, 1587-1592
10. Shibuya, H., Yamaguchi, K., Shirakabe, K., Tonegawa, A., Gotoh, Y., Ueno, N., Irie, K., Nishida, E., and Matsumoto, K. (1996) Science 272, 1179-1182
11. Shirakabe, K., Yamaguchi, K., Shibuya, H., Irie, K., Matsuda, S., Moriguchi, T., Gotoh, Y., Matsumoto, K., and Nishida, E. (1997) J. Biol. Chem. 272, 8141-8144
12. Yamaguchi, K., Shirakabe, K., Shibuya, H., Irie, K., Oishi, I., Ueno, N., Taniguchi, T., Nishida, E., and Matsumoto, K. (1995) Science 270, 2008-2011
13. Topper, J. N., Cai, J., Qiu, Y., Anderson, K. R., Xu, Y. Y., Deeds, J. D., Feeley, R., Gimeno, C. J., Woolf, E. A., Tayber, O., Mays, G. G., Sampson, B. A., Schoen, F. J., Gimbrone, M. A., Jr., and Falb, D. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 9314-9319
14. Topper, J. N., DiChiara, M. R., Brown, J. D., Williams, A. J., Falb, D., Collins, T., and Gimbrone, M. A., Jr. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 9506-9511
15. Topper, J. N., Cai, J., Falb, D., and Gimbrone, M. A., Jr. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 10417-10422
16. Topper, J. N., Cai, J., Stavrakis, G., Anderson, K. R., Woolf, E. A., Sampson, B. A., Schoen, F. J., Falb, D., and Gimbrone, M. A., Jr. (1998) Circulation 98, 2396-2403
17. Davis, R. J. (1995) Mol. Reprod. Dev. 42, 459-467
18. Errede, B., Cade, R. M., Yashar, B. M., Kamada, Y., Levin, D. E., Irie, K., and Matsumoto, K. (1995) Mol. Reprod. Dev. 42, 477-485
19. Karin, M., and Delhase, M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 9067-9069
20. Lee, F. S., Peters, R. T., Dang, L. C., and Maniatis, T. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 9319-9324
21. Fuchs, S. Y., Adler, V., Pincus, M. R., and Ronai, Z. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 10541-10546
22. Abdollah, S., Macias-Silva, M., Tsukazaki, T., Hayashi, H., Attisano, L., and Wrana, J. L. (1997) J. Biol. Chem. 272, 27678-27685
23. Souchelnytskyi, S., Tamaki, K., Engstrom, U., Wernstedt, C., ten Dijke, P., and Heldin, C. H. (1997) J. Biol. Chem. 272, 28107-28115
24. Pouponnot, C., Jayaraman, L., and Massague, J. (1998) J. Biol. Chem. 273, 22865-22868
25. Janknecht, R., Wells, N. J., and Hunter, T. (1998) Genes Dev. 12, 2114-2119
26. Li, Y. S., Shyy, J. Y., Li, S., Lee, J., Su, B., Karin, M., and Chien, S. (1996) Mol. Cell Biol. 16, 5947-5954
27. Jo, H., Sipos, K., Go, Y. M., Law, R., Rong, J., and McDonald, J. M. (1997) J. Biol. Chem. 272, 1395-1401
28. Shioda, T., Lechleider, R. J., Dunwoodie, S. L., Li, H., Yahata, T., de Caestecker, M. P., Fenner, M. H., Roberts, A. B., and Isselbacher, K. J. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 9785-9790
29. Atfi, A., Buisine, M., Mazars, A., and Gespach, C. (1997) J. Biol. Chem. 272, 24731-24734
30. Atfi, A., Djelloul, S., Chastre, E., Davis, R., and Gespach, C. (1997) J. Biol. Chem. 272, 1429-1432
31. Frey, R. S., and Mulder, K. M. (1997) Cancer Res. 57, 628-633
32. Hayashi, H., Abdollah, S., Qiu, Y., Cai, J., Xu, Y. Y., Grinnell, B. W., Richardson, M. A., Topper, J. N., Gimbrone, M. A., Jr., Wrana, J. L., and Falb, D. (1997) Cell 89, 1165-1173
33. Gimbrone, M. A., Jr., Nagel, T., and Topper, J. N. (1997) J. Clin. Invest. 99, 1809-1813
34. Yamazaki, T., Komuro, I., Kudoh, S., Zou, Y., Shiojima, I., Mizuno, T., Takano, H., Hiroi, Y., Ueki, K., Tobe, K., Kadowaki, T., Nagai, R., and Yazaki, Y. (1995) J. Clin. Invest. 96, 438-446