Endowing RNase H-inactive antisense with catalytic activity: 2-5A-morphants

Bioconjugate Chemistry

Volumn 16, Issue 2, 2005, Pages 383-390

  Zhou, Longhu ^a   Civitello, Edgar R ^a   Gupta, Nidhi ^a   Silverman, Robert H ^b   Molinaro, Ross J ^b,c   Anderson, David E ^d   Torrence, Paul F ^a  

^a NORTHERN ARIZONA UNIVERSITY   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c CLEVELAND STATE UNIVERSITY   (United States)

^d NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIUM HYDROXIDE; CATALYST ACTIVITY; FLUORINE COMPOUNDS; SYNTHESIS (CHEMICAL);

ANTISENSE; LARGE-SCALES; RNASE H; SOLID PHASE SYNTHESIS; SOLUTION-SYNTHESIS; SYNTHESISED; SYNTHETIC APPROACH; SYNTHONS; TERT-BUTYLDIMETHYLSILYL; TETRAMERS;

OLIGOMERS;

2',5' OLIGOADENYLIC ACID; 5' PHOSPHORYLADENYLYL(2'-5')ADENYLYL(2'-5')ADENYLYL(2'-5')ADENOSIN(P5'A2'P5'A2'P5'A2'P5'A2' TETRAMER 2 5A; MORPHOLINE DERIVATIVE; TETRAMER; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CATALYSIS; DRUG ACTIVITY; DRUG CONJUGATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG INHIBITION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; OXIDATION; SOLID PHASE SYNTHESIS; TRANSLATION REGULATION;

EID: 15344345666     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc049778q     Document Type: Article

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