-
1
-
-
11944267365
-
Antisense oligonucleotides: A new therapeutic principle
-
Uhlmann, E., and Peyman, A. (1990) Antisense oligonucleotides: a new therapeutic principle. Chem. Rev. 90, 544-584.
-
(1990)
Chem. Rev.
, vol.90
, pp. 544-584
-
-
Uhlmann, E.1
Peyman, A.2
-
2
-
-
0027228277
-
Current concepts in antisense drug design
-
Milligan, J. F., Matteucci, M. D., and Martin, J. C. (1993) Current concepts in antisense drug design. J. Med. Chem. 36, 1923-1937.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 1923-1937
-
-
Milligan, J.F.1
Matteucci, M.D.2
Martin, J.C.3
-
3
-
-
0032998423
-
Keeping the biotechnology of antisense in context
-
Stein, C. A. (1999) Keeping the biotechnology of antisense in context. Nat. Biotechnol. 17, 209.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 209
-
-
Stein, C.A.1
-
4
-
-
0029093853
-
Backbone modifications in oligonucleotides and peptide nucleic acid systems
-
and references therein
-
Mesmaeker, A. D., Altmann, K.-H., Waldner, A., and Wendeborn, S. (1995) Backbone modifications in oligonucleotides and peptide nucleic acid systems. Curr. Opin. Struct. Biol. 5, 343-355, and references therein.
-
(1995)
Curr. Opin. Struct. Biol.
, vol.5
, pp. 343-355
-
-
Mesmaeker, A.D.1
Altmann, K.-H.2
Waldner, A.3
Wendeborn, S.4
-
5
-
-
0032079356
-
The 2-5A system: Modulation of viral and cellular processes through acceleration of RNA degradation
-
Player, M., and Torrence, P. F. (1998) The 2-5A system: modulation of viral and cellular processes through acceleration of RNA degradation. Pharmacol. Ther. 78, 55-113.
-
(1998)
Pharmacol. Ther.
, vol.78
, pp. 55-113
-
-
Player, M.1
Torrence, P.F.2
-
6
-
-
0027690205
-
2′,5′-oligoadenylate: Antisense chimeras - Synthesis and properties
-
Lesiak, K., Khamnei, S., and Torrence, P. F. (1993) 2′,5′-Oligoadenylate: antisense chimeras - synthesis and properties. Bioconjugate Chem. 4, 467-472.
-
(1993)
Bioconjugate Chem.
, vol.4
, pp. 467-472
-
-
Lesiak, K.1
Khamnei, S.2
Torrence, P.F.3
-
7
-
-
0028169329
-
Blockage of NF-κB signaling by selective ablation of an mRNA target by 2-5A antisense chimeras
-
Maran, A., Maitra, R. K., Kumar, A., Dong, B., Xiao, W., Li, G., Williams, B. R. G., Torrence, P. F., and Silverman, R. H. (1994) Blockage of NF-κB signaling by selective ablation of an mRNA target by 2-5A antisense chimeras. Science 265, 789-792.
-
(1994)
Science
, vol.265
, pp. 789-792
-
-
Maran, A.1
Maitra, R.K.2
Kumar, A.3
Dong, B.4
Xiao, W.5
Li, G.6
Williams, B.R.G.7
Torrence, P.F.8
Silverman, R.H.9
-
8
-
-
0031042434
-
Targeting RNA decay with 2′,5′ oligoadenylate-antisense in respiratory syncytial virus-infected cells
-
Cirino, N. M., Li, G., Xiao, W., Torrence, P. F., and Silverman, R. H. (1997) Targeting RNA decay with 2′,5′ oligoadenylate-antisense in respiratory syncytial virus-infected cells. Proc. Natl. Acad. Sci. U.S.A. 94, 1937-1942.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 1937-1942
-
-
Cirino, N.M.1
Li, G.2
Xiao, W.3
Torrence, P.F.4
Silverman, R.H.5
-
9
-
-
0031746651
-
Targeting RNase L to human immunodeficiency virus RNA with 2-5A-antisense
-
Player, M. R., Maitra, R. K., Silverman, R. H., and Torrence, P. F. (1998) Targeting RNase L to human immunodeficiency virus RNA with 2-5A-antisense. Antivir. Chem., Chemother. 9, 225-231.
-
(1998)
Antivir. Chem., Chemother.
, vol.9
, pp. 225-231
-
-
Player, M.R.1
Maitra, R.K.2
Silverman, R.H.3
Torrence, P.F.4
-
10
-
-
0032560140
-
Nuclease-resistant composite 2′,5′-oligoadenylate-3′,5′-oligonucleotides for the targeted destruction of RNA: 2-5A-iso-antisense
-
Xiao, W., Li, G., Player, M. R., Maitra, R. K., Waller, C. F., Silverman, R. H., and Torrence, P. F. (1998) Nuclease-resistant composite 2′,5′-oligoadenylate-3′,5′-oligonucleotides for the targeted destruction of RNA: 2-5A-iso-antisense. J. Med. Chem. 41, 1531-1539.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 1531-1539
-
-
Xiao, W.1
Li, G.2
Player, M.R.3
Maitra, R.K.4
Waller, C.F.5
Silverman, R.H.6
Torrence, P.F.7
-
11
-
-
0033018595
-
2′,5′-oligoadenylate-peptide nucleic acids (2-5A-PNAs) activate RNase L
-
Verheijen, J. C., van der Marel, G. A., van Boom, J. H., Bayly, S. F., Player, M. R., and Torrence, P. F. (1999) 2′,5′-Oligoadenylate-peptide nucleic acids (2-5A-PNAs) activate RNase L. Bioorg. Med. Chem. 7, 449-455.
-
(1999)
Bioorg. Med. Chem.
, vol.7
, pp. 449-455
-
-
Verheijen, J.C.1
Van der Marel, G.A.2
Van Boom, J.H.3
Bayly, S.F.4
Player, M.R.5
Torrence, P.F.6
-
12
-
-
0034686432
-
Convergent synthesis of ribonuclease L-active 2′,5′-oligo-adenylate-peptide nucleic acids
-
Wang, Z., Chen, L., Bayly, S. F., and Torrence, P. F. (2000) Convergent synthesis of ribonuclease L-active 2′,5′-oligo-adenylate-peptide nucleic acids. Bioorg. Med. Chem. Lett. 10, 1357-1360.
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, pp. 1357-1360
-
-
Wang, Z.1
Chen, L.2
Bayly, S.F.3
Torrence, P.F.4
-
13
-
-
0034960390
-
Chemistry and biochemistry of 2′, 5′-oligoadenylate-based antisense strategy
-
Adah, S. A., Bayly, S. F., Cramer, H., Silverman, R. H., and Torrence, P. F. (2001) Chemistry and biochemistry of 2′, 5′-oligoadenylate-based antisense strategy. Curr. Med. Chem. 8, 1189-1212.
-
(2001)
Curr. Med. Chem.
, vol.8
, pp. 1189-1212
-
-
Adah, S.A.1
Bayly, S.F.2
Cramer, H.3
Silverman, R.H.4
Torrence, P.F.5
-
14
-
-
0028132046
-
Synthesis of a 5′-thiophosphate analogue of 2-5A, a phosphatase resistant activator of the 2-5A-dependent ribonuclease
-
Xiao, W., Li, G., Lesiak, K., Dong, B., Silverman, R. H., and Torrence, P. F. (1994) Synthesis of a 5′-thiophosphate analogue of 2-5A, a phosphatase resistant activator of the 2-5A-dependent ribonuclease. Bioorg. Med. Chem. Lett. 4, 2609-2614.
-
(1994)
Bioorg. Med. Chem. Lett.
, vol.4
, pp. 2609-2614
-
-
Xiao, W.1
Li, G.2
Lesiak, K.3
Dong, B.4
Silverman, R.H.5
Torrence, P.F.6
-
15
-
-
0025770162
-
8-Methyladenosine-substituted analogues of 2-5A: Synthesis and their biological activities
-
Kitade, Y., Nakata, Y., Hirota, K., Maki, Y., Pabuccuoglu, A., and Torrence, P. F. (1991) 8-Methyladenosine-substituted analogues of 2-5A: synthesis and their biological activities. Nucleic Acids Res. 19, 4103-4108.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 4103-4108
-
-
Kitade, Y.1
Nakata, Y.2
Hirota, K.3
Maki, Y.4
Pabuccuoglu, A.5
Torrence, P.F.6
-
16
-
-
0026758250
-
Convenient method for the synthesis of C-alkylated purine nucleosides: Palladium-catalyzed cross-coupling reaction of halogenopurine nucleosides with trialkylaluminums
-
Hirota, K., Kitade, Y., Kanbe, Y., and Maki, Y. (1992) Convenient method for the synthesis of C-alkylated purine nucleosides: palladium-catalyzed cross-coupling reaction of halogenopurine nucleosides with trialkylaluminums. J. Org. Chem. 57, 5268-5270.
-
(1992)
J. Org. Chem.
, vol.57
, pp. 5268-5270
-
-
Hirota, K.1
Kitade, Y.2
Kanbe, Y.3
Maki, Y.4
-
17
-
-
0023651145
-
Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides
-
Inoue, H., Hayase, Y., Imura, A., Iwai. S., Miura, K., and Ohtsuka, E. (1987) Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides. Nucleic Acids Res. 15, 6131-6148.
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 6131-6148
-
-
Inoue, H.1
Hayase, Y.2
Imura, A.3
Iwai, S.4
Miura, K.5
Ohtsuka, E.6
-
18
-
-
0029995154
-
Cleavage of oligoribonucleotides by the 2′,5′-oligoadenylate-dependent ribonuclease L
-
Carroll, S. S., Chen, E., Viscount, T., Geib, J., Sardana, M. K., Gehman, J., and Kuo, L. C. (1996) Cleavage of oligoribonucleotides by the 2′,5′-oligoadenylate-dependent ribonuclease L. J. Biol. Chem. 271, 4988-4992.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4988-4992
-
-
Carroll, S.S.1
Chen, E.2
Viscount, T.3
Geib, J.4
Sardana, M.K.5
Gehman, J.6
Kuo, L.C.7
-
19
-
-
0036775461
-
A comparative study on the biological properties of 2′,5′-oligoadenylates with purified human RNase L expressed in E. coli
-
Yoshimura, A., Nakanishi, M., Yatome, C., and Kitade, Y. (2002) A comparative study on the biological properties of 2′,5′-oligoadenylates with purified human RNase L expressed in E. coli. J. Biochem. 132, 643-648.
-
(2002)
J. Biochem.
, vol.132
, pp. 643-648
-
-
Yoshimura, A.1
Nakanishi, M.2
Yatome, C.3
Kitade, Y.4
-
20
-
-
0024804759
-
-
Dahlberg, J. E., Abelson, J. N., Eds.; Academic Press, Inc.: San Diego
-
Puglisi, J. D. and Tinoco, I., Jr. In Methods in Enzymology; Dahlberg, J. E., and Abelson, J. N., Eds.; Academic Press, Inc.: San Diego, 1989: Vol. 180, pp 304-325.
-
(1989)
Methods in Enzymology
, vol.180
, pp. 304-325
-
-
Puglisi, J.D.1
Tinoco I., Jr.2
|