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Volumn 1, Issue 3, 1999, Pages 307-315

2-5A-antisense chimeras: Inhibitors of respiratory syncytial virus infection

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLIC ACID;

EID: 0032993463     PISSN: 14648431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (16)

References (82)
  • 1
    • 0032428770 scopus 로고    scopus 로고
    • Respiratory syncytial virus (RSV) disease and prospects for Its control
    • Wyde PR: Respiratory syncytial virus (RSV) disease and prospects for Its control. Antiviral Res (1998) 39:63-79. •• Most recent and useful review of control strategies for RSV.
    • (1998) Antiviral Res , vol.39 , pp. 63-79
    • Wyde, P.R.1
  • 2
    • 0029639821 scopus 로고
    • Update. Respiratory syncytial virus activity - United States, 1995-96 season
    • Update. Respiratory syncytial virus activity - United States, 1995-96 season. Morbid Mortal Wkly Rep (1995) 44:900-902.
    • (1995) Morbid Mortal Wkly Rep , vol.44 , pp. 900-902
  • 3
    • 2442761149 scopus 로고
    • New vaccine development establishing priorities. Report of the Institute of Medicine to the National Institute of Allergy and Infectious Diseases
    • New vaccine development establishing priorities. Report of the Institute of Medicine to the National Institute of Allergy and Infectious Diseases. Diseases of Importance in the United States (1985) 1:9.
    • (1985) Diseases of Importance in the United States , vol.1 , pp. 9
  • 4
    • 0028129257 scopus 로고
    • Respiratory syncytial virus infections in children
    • Blanchard B: Respiratory syncytial virus infections in children. Arch Pediatr (1994) 1:738-745.
    • (1994) Arch Pediatr , vol.1 , pp. 738-745
    • Blanchard, B.1
  • 5
    • 0029764365 scopus 로고    scopus 로고
    • Perspectives for the chemotherapy of respiratory syncytial virus (RSV) infections
    • De Clercq E: Perspectives for the chemotherapy of respiratory syncytial virus (RSV) infections. Int J Antimicrob Ag (1996) 7:193-202. • This review especially emphasizes medicinal chemical approaches.
    • (1996) Int J Antimicrob Ag , vol.7 , pp. 193-202
    • De Clercq, E.1
  • 6
    • 0000089226 scopus 로고    scopus 로고
    • Fields Virology, Fields BN, Knipe DM, Howley PM, Chanock RM, Melnick JL, Monath TP, Roizman B, Straus SE (Eds). Lippincott-Raven, Philadelphia, PA
    • Collins PL, McIntosh K, Chanock RM: Respiratory syncytial virus. In: Fields Virology, Fields BN, Knipe DM, Howley PM, Chanock RM, Melnick JL, Monath TP, Roizman B, Straus SE (Eds). Lippincott-Raven, Philadelphia, PA (1996):1313-1351. •• Excellent review of molecular biology of RSV.
    • (1996) Respiratory Syncytial Virus , pp. 1313-1351
    • Collins, P.L.1    McIntosh, K.2    Chanock, R.M.3
  • 7
    • 0344710582 scopus 로고
    • Respiratory syncytial virus: Antiviral therapy
    • Jefferies DJ, De Clercq E (Eds). John Wiley and Sons, New York
    • Carmack MA, Prober CG: Respiratory syncytial virus: Antiviral therapy. In: Antiviral Chemotherapy, Jefferies DJ, De Clercq E (Eds). John Wiley and Sons, New York (1995):357-390. • Deals with some of the short-comings of ribavirin as an anit-RSV agent.
    • (1995) Antiviral Chemotherapy , pp. 357-390
    • Carmack, M.A.1    Prober, C.G.2
  • 8
    • 0028537459 scopus 로고
    • Viral infections in severely immunocompromised cancer patients
    • Devine SM, Wingard JR: Viral infections in severely immunocompromised cancer patients. Support Care Cancer (1994) 2:355-368.
    • (1994) Support Care Cancer , vol.2 , pp. 355-368
    • Devine, S.M.1    Wingard, J.R.2
  • 9
  • 10
    • 0032926030 scopus 로고    scopus 로고
    • Respiratory syncytial virus pneumonia among the elderly: An assessment of disease burden
    • Han LL, Alexander JP, Anderson LJ: Respiratory syncytial virus pneumonia among the elderly: An assessment of disease burden. J Infect Dis (1999) 179:25-30.
    • (1999) J Infect Dis , vol.179 , pp. 25-30
    • Han, L.L.1    Alexander, J.P.2    Anderson, L.J.3
  • 11
    • 0032191081 scopus 로고    scopus 로고
    • Pneumonia in residents of long-term care facilitates: Epidemiology, etiology, management, and prevention
    • Muder RR: Pneumonia in residents of long-term care facilitates: Epidemiology, etiology, management, and prevention. Am J Med (1998) 105:319-330.
    • (1998) Am J Med , vol.105 , pp. 319-330
    • Muder, R.R.1
  • 12
    • 0032211272 scopus 로고    scopus 로고
    • Respiratory syncytial virus infection in older persons
    • Falsey AR: Respiratory syncytial virus infection in older persons. Vaccine (1998) 16:1775-1778.
    • (1998) Vaccine , vol.16 , pp. 1775-1778
    • Falsey, A.R.1
  • 14
    • 0029852012 scopus 로고    scopus 로고
    • Management of viral infections in bone marrow transplant recipients
    • Dix SP, Wingard JR: Management of viral infections in bone marrow transplant recipients. Clin Immunotherapeut (1996) 6:352-382.
    • (1996) Clin Immunotherapeut , vol.6 , pp. 352-382
    • Dix, S.P.1    Wingard, J.R.2
  • 15
    • 0024429871 scopus 로고
    • Respiratory syncytial virus-Induced acute lung injury in adult patients with bone marrow transplants: A clinical approach and review of the literature
    • Hertz MI, Englund JA, Snover D, Bitterman PB, McGlave PB: Respiratory syncytial virus-Induced acute lung injury in adult patients with bone marrow transplants: a clinical approach and review of the literature. Medicine (1989) 68:269-281.
    • (1989) Medicine , vol.68 , pp. 269-281
    • Hertz, M.I.1    Englund, J.A.2    Snover, D.3    Bitterman, P.B.4    McGlave, P.B.5
  • 17
    • 0027376757 scopus 로고
    • Presence of respiratory syncytial virus genomic sequences in middle ear fluid and its relationship to expression of cytokines and cell adhesion molecules
    • Okamoto Y, Kudo K, Ishikawa K, Ito E, Togawa K, Saito I, Moro I, Patel JA, Ogra PL: Presence of respiratory syncytial virus genomic sequences in middle ear fluid and its relationship to expression of cytokines and cell adhesion molecules. J Infect Dis (1993) 168:1277-1281.
    • (1993) J Infect Dis , vol.168 , pp. 1277-1281
    • Okamoto, Y.1    Kudo, K.2    Ishikawa, K.3    Ito, E.4    Togawa, K.5    Saito, I.6    Moro, I.7    Patel, J.A.8    Ogra, P.L.9
  • 18
    • 0027424929 scopus 로고
    • Impact of respiratory virus-infection in patients with chronic chest disease
    • Wiselka MJ, Kent J, Cookson JB, Nicholson KG: Impact of respiratory virus-infection in patients with chronic chest disease. Epidemiol Infect (1993) 111:337-346.
    • (1993) Epidemiol Infect , vol.111 , pp. 337-346
    • Wiselka, M.J.1    Kent, J.2    Cookson, J.B.3    Nicholson, K.G.4
  • 19
    • 0031729398 scopus 로고    scopus 로고
    • Viruses and asthma exacerbations
    • Papadopoulos NG, Johnston SL Viruses and asthma exacerbations. Thorax (1998) 53:913-914.
    • (1998) Thorax , vol.53 , pp. 913-914
    • Papadopoulos, N.G.1    Johnston, S.L.2
  • 20
    • 0031772653 scopus 로고    scopus 로고
    • Ventricular arrhythmia associated with respiratory syncytial viral infection
    • Huang M, Bigos D, Levine M: Ventricular arrhythmia associated with respiratory syncytial viral infection. Pediatr Cardiol (1998) 19:498-500.
    • (1998) Pediatr Cardiol , vol.19 , pp. 498-500
    • Huang, M.1    Bigos, D.2    Levine, M.3
  • 22
    • 0032428340 scopus 로고    scopus 로고
    • Anaphylactic sensitization to aeroantigen during respiratory virus infection
    • O'Donnell DR, Openshaw PJM: Anaphylactic sensitization to aeroantigen during respiratory virus infection. Clin Exp Allergy (1998) 28:1501-1508.
    • (1998) Clin Exp Allergy , vol.28 , pp. 1501-1508
    • O'Donnell, D.R.1    Openshaw, P.J.M.2
  • 23
    • 0026491103 scopus 로고
    • Viral infection and alpha interferon in SIDS
    • Howatson AG: Viral infection and alpha interferon in SIDS. J Clin Pathol (1992) 45:25-28.
    • (1992) J Clin Pathol , vol.45 , pp. 25-28
    • Howatson, A.G.1
  • 24
    • 0031754941 scopus 로고    scopus 로고
    • Viruses and asthma
    • Johnston SL: Viruses and asthma. Allergy (1998) 53:922-932.
    • (1998) Allergy , vol.53 , pp. 922-932
    • Johnston, S.L.1
  • 27
    • 0031683919 scopus 로고    scopus 로고
    • Palivizumab, a humanized respiratory syncytial virus monoclonal antobody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants
    • The IMPACT-RSV Study Group: Palivizumab, a humanized respiratory syncytial virus monoclonal antobody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. Pediatrics (1998) 102:531-537.
    • (1998) Pediatrics , vol.102 , pp. 531-537
  • 28
    • 0030959478 scopus 로고    scopus 로고
    • Reduction of respiratory syncytial virus hospitalization among premature infants and infants with broncopulmonary dysplasla using respiratory syncytial virus immune globulin prophylaxis
    • The PREVENT Study Group: Reduction of respiratory syncytial virus hospitalization among premature infants and infants with broncopulmonary dysplasla using respiratory syncytial virus immune globulin prophylaxis. Pediatrics (1997) 99:93-99.
    • (1997) Pediatrics , vol.99 , pp. 93-99
  • 30
    • 0003095520 scopus 로고    scopus 로고
    • 2-5A-Dependent RNase L: A regulated endoribonuclease in the interferon system
    • D'Alessio G, Riordan JF (Eds), Academic Press, New York
    • Silverman RH: 2-5A-Dependent RNase L: a regulated endoribonuclease in the interferon system. In: Ribonucleases: Structure and Function. D'Alessio G, Riordan JF (Eds), Academic Press, New York (1997):515-551. •• Comprehensive review of RNase L.
    • (1997) Ribonucleases: Structure and Function , pp. 515-551
    • Silverman, R.H.1
  • 31
    • 0032079356 scopus 로고    scopus 로고
    • The 2-5A system: Modulation of viral and cellular processes through acceleration of RNA degradation
    • Player MR, Torrence PF: The 2-5A system: modulation of viral and cellular processes through acceleration of RNA degradation. Pharmacol Ther (1998) 78:55-113. •• Comprehensive review of all aspects of 2-5A including synthesis and properties of related 2′,5′-linked oligonucleotides.
    • (1998) Pharmacol Ther , vol.78 , pp. 55-113
    • Player, M.R.1    Torrence, P.F.2
  • 34
    • 0022526683 scopus 로고
    • 12U), induces accumulation of 2′,5′-oligoadenylates in mouse tissues
    • 12U), induces accumulation of 2′,5′-oligoadenylates in mouse tissues. Biochem Biophys Res Commun (1986) 138:40-46.
    • (1986) Biochem Biophys Res Commun , vol.138 , pp. 40-46
    • Hearl, W.G.1    Johnston, M.I.2
  • 35
    • 0022017441 scopus 로고
    • Analogue inhibitor of 2-5A action: Effect on the interferon-mediated inhibition of encephalomyocarditis virus replication
    • Watling D, Serafinowska HT, Reese CB, Kerr IM: Analogue inhibitor of 2-5A action: effect on the interferon-mediated inhibition of encephalomyocarditis virus replication. EMBO J (1985) 4:431-436.
    • (1985) EMBO J , vol.4 , pp. 431-436
    • Watling, D.1    Serafinowska, H.T.2    Reese, C.B.3    Kerr, I.M.4
  • 36
    • 0027270867 scopus 로고
    • A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon
    • Hassel BA, Zhou A, Sotomayor C, Maran A, Silverman RH: A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon. EMBO J (1993) 12:3297-3304.
    • (1993) EMBO J , vol.12 , pp. 3297-3304
    • Hassel, B.A.1    Zhou, A.2    Sotomayor, C.3    Maran, A.4    Silverman, R.H.5
  • 37
  • 39
    • 0023650344 scopus 로고
    • Constitutive expression of (2′-5′) oligo a synthetase confers resistance to picornavirus infection
    • Chebath J, Benech P, Revel M, Vigneron M: Constitutive expression of (2′-5′) oligo A synthetase confers resistance to picornavirus infection. Nature (1987) 330:587-588.
    • (1987) Nature , vol.330 , pp. 587-588
    • Chebath, J.1    Benech, P.2    Revel, M.3    Vigneron, M.4
  • 40
    • 0026057917 scopus 로고
    • Interferon action: Binding of viral RNA to the 40-kilodalton 2′-5′-oligoadenylate synthetase in interferon-treated HeLa cells infected with encephalomyocarditis virus
    • Gribaudo G, Lembo D, Cavallo G, Landolfo S, Lengyel P: Interferon action: binding of viral RNA to the 40-kilodalton 2′-5′-oligoadenylate synthetase in interferon-treated HeLa cells infected with encephalomyocarditis virus. J Virol (1991) 65:1748-1757.
    • (1991) J Virol , vol.65 , pp. 1748-1757
    • Gribaudo, G.1    Lembo, D.2    Cavallo, G.3    Landolfo, S.4    Lengyel, P.5
  • 41
    • 0018840814 scopus 로고
    • Anticellular and antiproliferative effects of pppA(2′p5′A)n
    • Hovanessian AG, Wood JN: Anticellular and antiproliferative effects of pppA(2′p5′A)n. Virology (1980) 101:81-90.
    • (1980) Virology , vol.101 , pp. 81-90
    • Hovanessian, A.G.1    Wood, J.N.2
  • 42
    • 0018130514 scopus 로고
    • Inhibition of protein synthesis by 2′-5′ linked adenine oligonucleotides in intact cells
    • Williams BRG, Kerr IM: Inhibition of protein synthesis by 2′-5′ linked adenine oligonucleotides in intact cells. Nature (1978) 276:88-90.
    • (1978) Nature , vol.276 , pp. 88-90
    • Williams, B.R.G.1    Kerr, I.M.2
  • 43
    • 0019794540 scopus 로고
    • Interferon action: RNA cleavage pattern of a (2′-5′)oligoadenylate-dependent endonuclease
    • Floyd-Smith G, Slattery E, Lengyel P: Interferon action: RNA cleavage pattern of a (2′-5′)oligoadenylate-dependent endonuclease. Science (1981) 212:1030-1032.
    • (1981) Science , vol.212 , pp. 1030-1032
    • Floyd-Smith, G.1    Slattery, E.2    Lengyel, P.3
  • 46
    • 0019142882 scopus 로고
    • Role of 2′,5′-oligo(adenylic acid) polymerase in the degradation of ribonuclelc acid linked to double-stranded ribonucleic acid by extracts of interferon-treated cells
    • Nilsen TW, Weissman SG, Baglioni C: Role of 2′,5′-oligo(adenylic acid) polymerase in the degradation of ribonuclelc acid linked to double-stranded ribonucleic acid by extracts of interferon-treated cells. Biochemistry (1980) 19:5574-5579.
    • (1980) Biochemistry , vol.19 , pp. 5574-5579
    • Nilsen, T.W.1    Weissman, S.G.2    Baglioni, C.3
  • 47
    • 0029995154 scopus 로고    scopus 로고
    • Cleavage of oligoribonucleotides by the 2′,5′-oligoadenylate-dependent ribonuclease L
    • Carroll SS, Chen E, Viscount T, Geib J, Sardana MK, Gehman J, Kuo LC: Cleavage of oligoribonucleotides by the 2′,5′-oligoadenylate-dependent ribonuclease L. J Biol Chem (1996) 271:4988-4992.
    • (1996) J Biol Chem , vol.271 , pp. 4988-4992
    • Carroll, S.S.1    Chen, E.2    Viscount, T.3    Geib, J.4    Sardana, M.K.5    Gehman, J.6    Kuo, L.C.7
  • 48
    • 0027394235 scopus 로고
    • Targeting RNA for degradation with a (2′-5′)oligoadenylate-antisense chimera
    • Torrence PF, Maitra RK, Lesiak K, Khamnei S, Zhou A, Silverman RH: Targeting RNA for degradation with a (2′-5′)oligoadenylate-antisense chimera. Proc Natl Acad Sci USA (1993) 90:1300-1304. •• Germinal paper describing the concept of 2-5A-antisense.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1300-1304
    • Torrence, P.F.1    Maitra, R.K.2    Lesiak, K.3    Khamnei, S.4    Zhou, A.5    Silverman, R.H.6
  • 49
    • 0027690205 scopus 로고
    • 2′,5′-Oligoadenylate antisense chimeras synthesis and properties
    • Lesiak K, Khamnei S, Torrence PF: 2′,5′-Oligoadenylate antisense chimeras synthesis and properties. Bioconjug Chem (1993) 4:467-472. •• Synthesis of 2-5A-antisense molecules.
    • (1993) Bioconjug Chem , vol.4 , pp. 467-472
    • Lesiak, K.1    Khamnei, S.2    Torrence, P.F.3
  • 50
    • 0028169329 scopus 로고
    • Blockage of NF-xB signaling by selective ablation of an mRNA target by 2-5A antisense chimeras
    • Maran A, Maitra RK, Kumar A, Dong B, Xiao W, Li G, Williams BRG, Torrence PF, Silverman RH: Blockage of NF-xB signaling by selective ablation of an mRNA target by 2-5A antisense chimeras. Science (1994) 265:789-792. •• Description of ablation of PKR mRNA, protein, and biological function by 2-5A-antisense.
    • (1994) Science , vol.265 , pp. 789-792
    • Maran, A.1    Maitra, R.K.2    Kumar, A.3    Dong, B.4    Xiao, W.5    Li, G.6    Williams, B.R.G.7    Torrence, P.F.8    Silverman, R.H.9
  • 52
    • 0032560140 scopus 로고    scopus 로고
    • Nuclease-resistant composite 2′,5′-oligoadenylate-3′,5′-oligonucleotides for the targeted destruction of RNA: 2-5A-iso-antisense
    • Xiao W, Li G, Player MR, Maitra RK, Waller CF, Silverman RH, Torrence PF: Nuclease-resistant composite 2′,5′-oligoadenylate-3′,5′-oligonucleotides for the targeted destruction of RNA: 2-5A-iso-antisense. J Med Chem (1998) 41:1531-1539.
    • (1998) J Med Chem , vol.41 , pp. 1531-1539
    • Xiao, W.1    Li, G.2    Player, M.R.3    Maitra, R.K.4    Waller, C.F.5    Silverman, R.H.6    Torrence, P.F.7
  • 55
    • 0032566005 scopus 로고    scopus 로고
    • Targeted therapy of human malignant glioma in a mouse model by 2-5a antisense directed against telomerase RNA
    • Kondo S, Kondo Y, Li G, Silverman RH, Cowell JK: Targeted therapy of human malignant glioma in a mouse model by 2-5A antisense directed against telomerase RNA. Oncogene (1998) 16:3323-3330.
    • (1998) Oncogene , vol.16 , pp. 3323-3330
    • Kondo, S.1    Kondo, Y.2    Li, G.3    Silverman, R.H.4    Cowell, J.K.5
  • 56
    • 0027749681 scopus 로고
    • Induction of interferon in human leukocyte cultures by natural pathogenic respiratory viruses
    • Pitkäranta A, Hovi T: Induction of interferon in human leukocyte cultures by natural pathogenic respiratory viruses. J Interferon Res (1993) 13:423-426.
    • (1993) J Interferon Res , vol.13 , pp. 423-426
    • Pitkäranta, A.1    Hovi, T.2
  • 58
    • 0024574604 scopus 로고
    • Production of interferon in respiratory syncytial virus bronchiolitis
    • Isaacs D: Production of interferon in respiratory syncytial virus bronchiolitis. Arch Dis Child (1989) 64:92-95.
    • (1989) Arch Dis Child , vol.64 , pp. 92-95
    • Isaacs, D.1
  • 59
    • 0027490918 scopus 로고
    • Detection of alpha-interferon in nasopharyngeal secretions and sera in children infected with respiratory syncytial virus
    • Nakayama T, Sonoda S, Urano T, Sasaki K, Maehara N, Makino S: Detection of alpha-interferon in nasopharyngeal secretions and sera in children infected with respiratory syncytial virus. Pediatr Infect Dis J (1993) 12:925-929.
    • (1993) Pediatr Infect Dis J , vol.12 , pp. 925-929
    • Nakayama, T.1    Sonoda, S.2    Urano, T.3    Sasaki, K.4    Maehara, N.5    Makino, S.6
  • 60
    • 0026874239 scopus 로고
    • The limited role of the human interferon system response to respiratory syncytial virus challenge: Analysis and comparison to influenza virus challenge
    • Roberts NJ, Hiscott J, Signs DJ: The limited role of the human interferon system response to respiratory syncytial virus challenge: Analysis and comparison to influenza virus challenge. Microb Pathog (1992) 12:409-414.
    • (1992) Microb Pathog , vol.12 , pp. 409-414
    • Roberts, N.J.1    Hiscott, J.2    Signs, D.J.3
  • 61
    • 0029114720 scopus 로고
    • Respiratory syncytial virus-replication in human lung epithelial-cells - Inhibition by tumor-necrosis-factor-alpha and interferon-beta
    • Merolla R, Rebert NA, Tsiviste PT, Hoffmann SP, Panuska JR: Respiratory syncytial virus-replication in human lung epithelial-cells - inhibition by tumor-necrosis-factor-alpha and interferon-beta. Am J Respir Crit Care Med (1995) 152:1358-1366.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 1358-1366
    • Merolla, R.1    Rebert, N.A.2    Tsiviste, P.T.3    Hoffmann, S.P.4    Panuska, J.R.5
  • 62
    • 0027214362 scopus 로고
    • Alpha-2A-interferon for treatment of bronchiolitis caused by respiratory syncytial virus
    • Chipps BE, Sullivan WF, Portnoy JM: Alpha-2A-interferon for treatment of bronchiolitis caused by respiratory syncytial virus. Pediatr Infect Dis J (1993) 12:653-658.
    • (1993) Pediatr Infect Dis J , vol.12 , pp. 653-658
    • Chipps, B.E.1    Sullivan, W.F.2    Portnoy, J.M.3
  • 63
    • 0027329965 scopus 로고
    • Treatment of respiratory syncytial virus-infection with recombinant interferon alfa-2a
    • Sung RYT, Yin J, Oppenheimer SJ, Tam JS, Lau J: Treatment of respiratory syncytial virus-infection with recombinant interferon alfa-2a. Arch Dis Child (1993) 69:440-442.
    • (1993) Arch Dis Child , vol.69 , pp. 440-442
    • Sung, R.Y.T.1    Yin, J.2    Oppenheimer, S.J.3    Tam, J.S.4    Lau, J.5
  • 64
    • 0025359420 scopus 로고
    • The efficacy of intranasal interferon-alpha-2a in respiratory syncytial virus-infection in volunteers
    • Higgins PG, Barrow GI, Tyrrell DAJ, Isaacs D, Gauci CL: The efficacy of intranasal interferon-alpha-2a in respiratory syncytial virus-infection in volunteers. Antiviral Res (1990) 14:3-10.
    • (1990) Antiviral Res , vol.14 , pp. 3-10
    • Higgins, P.G.1    Barrow, G.I.2    Tyrrell, D.A.J.3    Isaacs, D.4    Gauci, C.L.5
  • 65
    • 0023819449 scopus 로고
    • A (2′-5′) An-dependent endonuclease: Tissue distribution in BALB/c mice and the effects of IFN-β-treatment and anti-IFN-α/β immunoglobulin on the levels of the enzyme
    • Floyd-Smith G, Denton JS: A (2′-5′) An-dependent endonuclease: tissue distribution in BALB/c mice and the effects of IFN-β-treatment and anti-IFN-α/β immunoglobulin on the levels of the enzyme. J Interferon Res (1988) 8:517-525.
    • (1988) J Interferon Res , vol.8 , pp. 517-525
    • Floyd-Smith, G.1    Denton, J.S.2
  • 66
    • 0024210199 scopus 로고
    • Age-dependent changes are observed in the levels of an enzyme mediator of interferon action: A (2′-5′) A(n)-dependent endoribonuclease
    • Floyd-Smith G, Denton JS: Age-dependent changes are observed in the levels of an enzyme mediator of interferon action: a (2′-5′) A(n)-dependent endoribonuclease. Proc Soc Exp Biol Med (1988) 189:329-337.
    • (1988) Proc Soc Exp Biol Med , vol.189 , pp. 329-337
    • Floyd-Smith, G.1    Denton, J.S.2
  • 67
    • 0031025249 scopus 로고    scopus 로고
    • DNA antisense therapy for asthma in an animal model
    • Nyce JW, Metzger WJ: DNA antisense therapy for asthma in an animal model. Nature (1997) 385:721-725.
    • (1997) Nature , vol.385 , pp. 721-725
    • Nyce, J.W.1    Metzger, W.J.2
  • 68
    • 0031042434 scopus 로고    scopus 로고
    • Targeting RNA decay with 2′,5′ oligoadenylate antisense in respiratory syncytial virus infected cells
    • Cirino NM, Li G, Xiao W, Torrence PF, Silverman RH: Targeting RNA decay with 2′,5′ oligoadenylate antisense in respiratory syncytial virus infected cells. Proc Natl Acad Sci USA (1997) 94:1937-1942. •• First description of inhibition of RSV by 2-5A-antisense, including evidence of specific mRNA destruction.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1937-1942
    • Cirino, N.M.1    Li, G.2    Xiao, W.3    Torrence, P.F.4    Silverman, R.H.5
  • 69
    • 0028132046 scopus 로고
    • Synthesis of a 5′-thiophosphate analogue of 2-5A, a phosphatase resistant activator of the 2-5A-dependent ribonuclease
    • Xiao W, Li G, Lesiak K, Dong B, Silverman RH, Torrence PF: Synthesis of a 5′-thiophosphate analogue of 2-5A, a phosphatase resistant activator of the 2-5A-dependent ribonuclease. Bioorg Med Chem Lett (1994) 4:2609-2614.
    • (1994) Bioorg Med Chem Lett , vol.4 , pp. 2609-2614
    • Xiao, W.1    Li, G.2    Lesiak, K.3    Dong, B.4    Silverman, R.H.5    Torrence, P.F.6
  • 70
    • 0030881695 scopus 로고    scopus 로고
    • Synthesis and properties of second-generation 2-5A-antisense chimeras with enhanced resistance to exonucleases
    • Li G, Xiao W, Torrence PF: Synthesis and properties of second-generation 2-5A-antisense chimeras with enhanced resistance to exonucleases. J Med Chem (1997) 40:2959-2966.
    • (1997) J Med Chem , vol.40 , pp. 2959-2966
    • Li, G.1    Xiao, W.2    Torrence, P.F.3
  • 71
    • 0033010079 scopus 로고    scopus 로고
    • 2-5A-DNA conjugate inhibition of respiratory syncytial virus replication: Effects of oligonucleotide structure modifications and RNA target site selection
    • in press
    • Barnard DL, Sidwell RW, Xiao W, Player MR, Adah SA, Torrence PF: 2-5A-DNA conjugate inhibition of respiratory syncytial virus replication: Effects of oligonucleotide structure modifications and RNA target site selection. Antiviral Res (1999) in press.
    • (1999) Antiviral Res
    • Barnard, D.L.1    Sidwell, R.W.2    Xiao, W.3    Player, M.R.4    Adah, S.A.5    Torrence, P.F.6
  • 72
    • 0032555288 scopus 로고    scopus 로고
    • Potent inhibition of respiratory syncytial virus replication using a 2-5A-antisense chimera targeted to signals within the virus genomic RNA
    • Player MR, Barnard DL, Torrence PF: Potent inhibition of respiratory syncytial virus replication using a 2-5A-antisense chimera targeted to signals within the virus genomic RNA. Proc Natl Acad Sci USA (1998) 95:8874-8879. •• Description of antigenomic RNA-targeted 2-5A-antisense.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8874-8879
    • Player, M.R.1    Barnard, D.L.2    Torrence, P.F.3
  • 73
    • 0027376439 scopus 로고
    • Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
    • Stein CA, Cheng YC: Antisense oligonucleotides as therapeutic agents - is the bullet really magical? Science (1993) 261:1004-1012. • This review, although from 1993, is still relevant in its description of problems in the field of antisense.
    • (1993) Science , vol.261 , pp. 1004-1012
    • Stein, C.A.1    Cheng, Y.C.2
  • 75
    • 0033594198 scopus 로고    scopus 로고
    • Phosphorothioate oligonucleotides inhibit RNase L thereby disabling a mechanism of interferon action
    • in press
    • Player MR, Torrence PF: Phosphorothioate oligonucleotides inhibit RNase L thereby disabling a mechanism of interferon action. Bioorg Med Chem Lett (1999) in press.
    • (1999) Bioorg Med Chem Lett
    • Player, M.R.1    Torrence, P.F.2
  • 76
    • 0028313602 scopus 로고
    • Development of 2′,5′-oligonucleotides as potential therapeutic agents
    • Torrence PF, Xiao W, Li G, Khamnei S: Development of 2′,5′-oligonucleotides as potential therapeutic agents. Curr Med Chem (1994) 1:176-191.
    • (1994) Curr Med Chem , vol.1 , pp. 176-191
    • Torrence, P.F.1    Xiao, W.2    Li, G.3    Khamnei, S.4
  • 77
    • 0031036222 scopus 로고    scopus 로고
    • Inhibition of respiratory syncytial virus replication by antisense oligodeoxyribonucleotides
    • Jairath S, Vargas PB, Hamlin HA, Field AK, Kilkuskie RE: Inhibition of respiratory syncytial virus replication by antisense oligodeoxyribonucleotides. Antiviral Res (1997) 33:201-213.
    • (1997) Antiviral Res , vol.33 , pp. 201-213
    • Jairath, S.1    Vargas, P.B.2    Hamlin, H.A.3    Field, A.K.4    Kilkuskie, R.E.5
  • 78
    • 0033526019 scopus 로고    scopus 로고
    • Discrimination between ribonuclease H- and ribonuclease L-mediated RNA degradation by 2′-O-methylated 2-5A-antlsense oligonucleotides
    • in press
    • Cramer H, Player MR, Torrence PF: Discrimination between ribonuclease H- and ribonuclease L-mediated RNA degradation by 2′-O-methylated 2-5A-antlsense oligonucleotides. Bioorg Med Chem Lett (1999) in press.
    • (1999) Bioorg Med Chem Lett
    • Cramer, H.1    Player, M.R.2    Torrence, P.F.3
  • 80
    • 0032131491 scopus 로고    scopus 로고
    • Selective mRNA degradation by antisense oligonucleotide-2,5A chimera: Involvement of RNase H and RNase L
    • 19981
    • Robbins I, Mitta G, Vichier-Guerre S, Sobol R, Ubysz A, Rayner B, Lebleu B: Selective mRNA degradation by antisense oligonucleotide-2,5A chimera: involvement of RNase H and RNase L. Biochimie (19981) 80:711-720.
    • Biochimie , vol.80 , pp. 711-720
    • Robbins, I.1    Mitta, G.2    Vichier-Guerre, S.3    Sobol, R.4    Ubysz, A.5    Rayner, B.6    Lebleu, B.7
  • 82
    • 2442767214 scopus 로고    scopus 로고
    • NATIONAL INSTITUTES OF HEALTH AND CLEVELAND CLINIC FOUNDATION (pending), US-08962690
    • NATIONAL INSTITUTES OF HEALTH AND CLEVELAND CLINIC FOUNDATION (pending), US-08962690.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.