Regulation of apoptosis by glutathione redox state in PC12 cells exposed simultaneously to iron and ascorbic acid

Free Radical Biology and Medicine

Volumn 38, Issue 8, 2005, Pages 1057-1072

  Hiroi, Mayo ^a   Ogihara, Tohru ^a   Hirano, Kazuya ^a   Hasegawa, Masashi ^a   Morinobu, Takao ^a   Tamai, Hiroshi ^a   Niki, Etsuo ^b  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Apoptosis; Ascorbic acid; Free radicals; Glutathione; Iron; Reduction potential

Indexed keywords

3 (2 HYDROXYPHENYL)ALANINE; ALPHA TOCOPHEROL; ASCORBIC ACID; FERROUS SULFATE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE ETHYL ESTER; HYDROXYL RADICAL; ISOPROSTANE DERIVATIVE; META TYROSINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LEVEL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MOLECULAR WEIGHT; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM;

EID: 15244348061     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2005.01.001     Document Type: Article

References (45)

1. V. Fellman, and K.O. Raivio Reperfusion injury as the mechanism of brain damage after perinatal asphyxia Pediatr. Res. 41 1997 599 606
2. G. Buonocore, S. Perrone, and R. Bracci Free radicals and brain damage in the newborn Biol. Neonate 79 2001 180 186
3. B. Halliwell, and J.M.C. Gutteridge Role of free radicals and catalytic metal ions in human disease: an overview Methods Enzymol. 186 1990 1 85
4. J. Bralet, L. Schreiber, and C. Bouvier Effect of acidosis and anoxia on iron delocalization from brain homogenates Biochem. Pharmacol. 43 1992 979 983
5. M. Shadid, G. Buonocore, F. Groenendaal, R. Moison, M. Ferrali, H.M. Berger, and F. van-Bel Effect of deferoxamine and allopurinol on non-protein-bound iron concentrations in plasma and cortical brain tissue of newborn lambs following hypoxia-ischemia Neurosci. Lett. 248 1998 5 8
6. C. Palmer, R.L. Roberts, and C. Bero Deferoxamine posttreatment reduces ischemic brain injury in neonatal rats Stroke 25 1994 1039 1045
7. C.A. Dorrepaal, H.M. Berger, M.J. Benders, D. van-Zoeren-Grobben, M. van-de-Bor, and F. van-Bel Nonprotein-bound iron in postasphyxial reperfusion injury of the newborn Pediatrics 98 1996 883 889
8. T. Ogihara, K. Hirano, H. Ogihara, K. Misaki, M. Hiroi, T. Morinobu, H.S. Kim, S. Ogawa, R. Ban, M. Hasegawa, and H. Tamai Non-protein-bound transition metals and hydroxyl radical generation in cerebrospinal fluid of newborn infants with hypoxic ischemic encephalopathy Pediatr. Res. 53 2003 594 599
9. E.C. Kaal, H. Veldman, P. Sodaar, E.A. Joosten, and P.R. Dop-Bar Oxidant treatment causes a dose-dependent phenotype of apoptosis in cultured motoneurons J. Neurosci. Res. 54 1998 778 786
10. J.G. Ren, R.L. Zheng, Y.M. Shi, B. Gong, and J.F. Li Apoptosis, redifferentiation and arresting proliferation simultaneously triggered by oxidative stress in human hepatoma cells Cell. Biol. Int. 22 1998 41 49
11. I. Kruman, A.J. Bruce-Keller, D. Bredesen, G. Waeg, and M.P. Mattson Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis J. Neurosci. 17 1997 5089 5100
12. F.Q. Schafer, and G.R. Buettner Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple Free Radic. Biol. Med. 30 2001 1191 1212
13. J. Cai, and D.P. Jones Superoxide in apoptosis: mitochondrial generation triggered by cytochrome c loss J. Biol. Chem. 273 1998 11401 11404
14. J.T. Hancock, R. Desikan, and S.T. Neill Cytochrome c, glutathione, and the possible role of redox potentials in apoptosis Ann. N. Y. Acad. Sci. 1010 2003 446 448
15. N.J. Sucher, N. Brose, D.L. Deitcher, M. Awobuluyi, G.P. Gasic, H. Bading, C.L. Cepko, M.E. Greenberg, R. Jahn, S.F. Heinemann, and S.A. Lipton Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells J. Biol. Chem. 268 1993 22299 22304
16. L.A. Greene, J.M. Aletta, A. Rukenstein, and S.H. Green PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation Methods Enzymol. 147 1987 207 216
17. J.M.C. Gutteridge, D.A. Rowley, and B. Halliwell Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts: detection of 'free' iron in biological systems by using bleomycin-dependent degradation of DNA Biochem. J. 199 1981 263 265
18. K. Hirano, T. Morinobu, H. Kim, M. Hiroi, R. Ban, S. Ogawa, H. Ogihara, H. Tamai, and T. Ogihara Blood transfusion increases radical promoting non-transferrin bound iron in preterm infants Arch. Dis. Child. Fetal Neonatal Ed. 84 2001 F188 F193
19. E. Morier-Teissier, N. Mestdagh, J.L. Bernier, and J.P. Hénichart Reduced and oxidized glutathione ratio in tumor cells: comparison of two measurement methods using HPLC and electrochemical detection J. Liquid Chromatogr. 16 1993 573 596
20. R. Singh, and L. Kats Catalysis of reduction of disulfide by selenol Anal. Biochem. 232 1995 86 91
21. T.P. Akerboom, and H. Sies Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples Methods Enzymol. 77 1981 373 382
22. N.R. Jana, E.A. Zemskov, G.H. Wang, and N. Nukina Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release Hum. Mol. Genet. 10 2001 1049 1059
23. S. Leung, M.E. O'Donnell, A. Martinez, and H.C. Palfrey Regulation by nerve growth factor and protein phosphorylation of Na/K/2Cl cotransport and cell volume in PC12 cells J. Biol. Chem. 269 1994 10581 10589
24. R.A. Kirkland, and J.L. Franklin Evidence for redox regulation of cytochrome C release during programmed neuronal death: antioxidant effects of protein synthesis and caspase inhibition J. Neurosci. 21 2001 1949 1963
25. T. Ogihara, H.S. Kim, K. Hirano, M. Imanishi, H. Ogihara, H. Tamai, R. Okamoto, and M. Mino Oxidation products of uric acid and ascorbic acid in preterm infants with chronic lung disease Biol. Neonate 73 1998 24 33
26. Y. Cheng, P. Wixom, M.R. James-Kracke, and A.Y. Sun Effects of extracellular ATP on Fe(2+)-induced cytotoxicity in PC-12 cells J. Neurochem. 63 1994 895 902
27. J.H. Song, M.S. Harris, and S.H. Shin Effects of fetal bovine serum on ferrous ion-induced oxidative stress in pheochromocytoma (PC12) cells Neurochem. Res. 26 2001 407 414
28. F. Si, G.M. Ross, and S.H. Shin Glutathione protects PC12 cells from ascorbate- and dopamine-induced apoptosis Exp. Brain Res. 123 1998 263 268
29. Y. Ma, L. Cao, T. Kawabata, T. Yoshin, B.B. Yang, and S. Okada Cupric nitrilotriacetate induces oxidative DNA damage and apoptosis in human leukemia HL-60 cells Free Radic. Biol. Med. 25 1998 568 575
30. C. Velez-Pardo, M. Jimenez-Del-Rio, H. Verschueren, G. Ebinger, and G. Vauquelin Dopamine and iron induce apoptosis in PC12 cells Pharmacol. Toxicol. 80 1997 76 84
31. C. Núñez-Millacura, V. Tapia, P. Muñoz, R.B. Maccioni, and M.T. Núñez An oxidative stress-mediated positive-feedback iron uptake loop in neuronal cells J. Neurochem. 82 2002 240 248
32. O. Han, M.L. Failla, A.D. Hill, E.R. Morris, and J.C. Smith Jr. Reduction of Fe(III) is required for uptake of nonheme iron by Caco-2 cells J. Nutr. 125 1995 1291 1299
33. J.M. May, Z.C. Qu, and S. Mendiratta Role of ascorbic acid in transferrin-independent reduction and uptake of iron by U-937 cells Biochem. Pharmacol. 57 1999 1275 1282
34. O.W. Griffith Biologic and pharmacologic regulation of mammalian glutathione synthesis Free Radic. Biol. Med. 27 1999 922 935
35. S.Y. Qian, and G.R. Buettner Iron and dioxygen chemistry is an important route to initiation of biological free radical oxidations: an electron paramagnetic resonance spin trapping study Free Radic. Biol. Med. 26 1999 1447 1456
36. J. Seyfried, F. Soldner, J.B. Schulz, T. Klockgether, K.A. Kovar, and U. Wullner Differential effects of l-buthionine sulfoximine and ethacrynic acid on glutathione levels and mitochondrial function in PC12 cells Neurosci. Lett. 264 1999 1 4
37. E. Obrador, J. Carretero, J.M. Esteve, J.A. Pellicer, A. Pascual, I. Petschen, and J.M. Estrela Glutamine potentiates TNF-α-induced tumor cytotoxicity Free Radic. Biol. Med. 31 2001 642 650
38. A.R. White, A.I. Bush, K. Beyreuther, C.L. Masters, and R. Cappai Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione J. Neurochem. 72 1999 2092 2098
39. R.S. Fernandes, and T.G. Cotter Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death Biochem. Pharmacol. 48 1994 675 681
40. W. Liu, M. Kato, A.A. Akhand, A. Hayakawa, H. Suzuki, T. Miyata, K. Kurokawa, Y. Hotta, N. Ishikawa, and I. Nakashima 4-Hydroxynonenal induces a cellular redox status-related activation of the caspase cascade for apoptotic cell death J. Cell Sci. 113 2000 635 641
41. D.W. Voehringer BCL-2 and glutathione: alterations in cellular redox state that regulate apoptosis sensitivity Free Radic. Biol. Med. 27 1999 945 950
42. Y. Ma, T. Ogino, T. Kawabata, J. Li, K. Eguchi, and S. Okada Cupric nitrilotriacetate-induced apoptosis in HL-60 cells association with lipid peroxidation, release of cytochrome c from mitochondria, and activation of caspase-3 Free Radic. Biol. Med. 27 1999 227 233
43. J.T. Hancock, R. Desikan, and S.J. Neill Does the redox status of cytochrome c act as a fail-safe mechanism in the regulation of programmed cell death? Free Radic. Biol. Med. 31 2001 697 703
44. E. Niki Vitamin C as an antioxidant World Rev. Nutr. Diet 64 1991 1 30
45. G.R. Buettner, and B.A. Jurkiewicz Catalytic metals, ascorbate and free radicals: combinations to avoid Radiat. Res. 145 1996 532 541