Cupric nitrilotriacetate induces oxidative DNA damage and apoptosis in human leukemia HL-60 cells

Free Radical Biology and Medicine

Volumn 25, Issue 4-5, 1998, Pages 568-575

  Ma, Yuxiang ^a   Cao, Liu ^b   Kawabata, Teruyuki ^a   Yoshino, Tadashi ^a   Yang, Burton B ^b   Okada, Shigeru ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Apoptosis; Copper; DNA damage; Free radicals; HL 60 cells; Reactive oxygen species

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ANTIOXIDANT; CATALASE; COPPER; COPPER DERIVATIVE; CUPRIC NITRILOTRIACETIC ACID; DIMETHYL SULFOXIDE; DNA FRAGMENT; FLUORESCEIN DERIVATIVE; FREE RADICAL; HEAT SHOCK PROTEIN; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; HUMAN; HUMAN CELL; LEUKEMIA CELL; OXIDATIVE STRESS; PRIORITY JOURNAL;

APOPTOSIS; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA DAMAGE; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HL-60 CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; KINETICS; NITRILOTRIACETIC ACID; ORGANOMETALLIC COMPOUNDS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES;

EID: 18144448088     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(98)00088-4     Document Type: Article

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