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Volumn 33, Issue 1, 2005, Pages 81-89

Treatments for choroidal and retinal neovascularization: A focus on oligonucleotide therapy and delivery for the regulation of gene function

Author keywords

Gene therapy; Neovascularization; Oligonucleotides; Vascular endothelial growth factor (VEGF)

Indexed keywords

ALPHA TOCOPHEROL; ANGIOGENESIS INHIBITOR; ANTISENSE OLIGONUCLEOTIDE; APTAMER; ASCORBIC ACID; BETA CAROTENE; DENDRIMER; DS 085; ENDONUCLEASE; FOMIVIRSEN; IMMUNOGLOBULIN F(AB) FRAGMENT; LIPOPLEX; LIPOSOME; NANOPARTICLE; NONSTEROID ANTIINFLAMMATORY AGENT; OLIGONUCLEOTIDE; PARVOVIRUS VECTOR; PEGAPTANIB; PHOTOSENSITIZING AGENT; PIGMENT EPITHELIUM DERIVED FACTOR; POLYGLACTIN; POLYNUCLEOTIDE; PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VASCULOTROPIN ANTIBODY; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; ZINC;

EID: 14744296810     PISSN: 14426404     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1442-9071.2005.00952.x     Document Type: Review
Times cited : (11)

References (102)
  • 1
    • 85047699046 scopus 로고    scopus 로고
    • Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1
    • Bainbridge JW, Mistry A, De Alwis M et al. Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1. Gene Ther 2002; 9: 320-6.
    • (2002) Gene Ther. , vol.9 , pp. 320-326
    • Bainbridge, J.W.1    Mistry, A.2    De Alwis, M.3
  • 2
    • 0032040010 scopus 로고    scopus 로고
    • Evaluating new retinal imaging techniques
    • Bressler NM. Evaluating new retinal imaging techniques. Arch Ophthalmol 1998; 116: 521-2.
    • (1998) Arch. Ophthalmol. , vol.116 , pp. 521-522
    • Bressler, N.M.1
  • 3
    • 0021263352 scopus 로고
    • Macular edema. A complication of diabetic retinopathy
    • Ferris FL, Patz A. Macular edema. A complication of diabetic retinopathy. Surv Ophthalmol 1984; 28 (Suppl.): 452-61.
    • (1984) Surv. Ophthalmol. , vol.28 , Issue.SUPPL. , pp. 452-461
    • Ferris, F.L.1    Patz, A.2
  • 4
    • 0028123090 scopus 로고
    • Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy
    • Adamis AP, Miller JW, Bernal MT et al. Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am J Ophthalmol 1994; 118 445-50.
    • (1994) Am. J. Ophthalmol. , vol.118 , pp. 445-450
    • Adamis, A.P.1    Miller, J.W.2    Bernal, M.T.3
  • 5
    • 0027942607 scopus 로고
    • Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
    • Aiello LP, Avery RL, Arrigg PG et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 1994; 331 1480-7.
    • (1994) N. Engl. J. Med. , vol.331 , pp. 1480-1487
    • Aiello, L.P.1    Avery, R.L.2    Arrigg, P.G.3
  • 6
    • 0027962667 scopus 로고
    • Detection of vascular endothelial growth factor messenger RNA and vascular endothelial growth factor-like activity in proliferative diabetic retinopathy
    • Malecaze F, Clamens S, Simorre-Pinatel V et al. Detection of vascular endothelial growth factor messenger RNA and vascular endothelial growth factor-like activity in proliferative diabetic retinopathy. Arch Ophthalmol 1994; 112: 1476-82.
    • (1994) Arch. Ophthalmol. , vol.112 , pp. 1476-1482
    • Malecaze, F.1    Clamens, S.2    Simorre-Pinatel, V.3
  • 8
    • 0031799124 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in the human retina and in nonproliferative diabetic retinopathy
    • Gerhardinger C, Brown LF, Roy S, Mizutani M, Zucker CL, Lorenzi M. Expression of vascular endothelial growth factor in the human retina and in nonproliferative diabetic retinopathy. Am J Pathol 1998; 152: 1453-62.
    • (1998) Am. J. Pathol. , vol.152 , pp. 1453-1462
    • Gerhardinger, C.1    Brown, L.F.2    Roy, S.3    Mizutani, M.4    Zucker, C.L.5    Lorenzi, M.6
  • 9
    • 0029739621 scopus 로고    scopus 로고
    • Localization of vascular endothelial growth factor in human retina and choroid
    • Lutty GA, McLeod DS, Merges C, Diggs A, Plouet J. Localization of vascular endothelial growth factor in human retina and choroid. Arch Ophthalmol 1996; 114: 971-7.
    • (1996) Arch. Ophthalmol. , vol.114 , pp. 971-977
    • Lutty, G.A.1    McLeod, D.S.2    Merges, C.3    Diggs, A.4    Plouet, J.5
  • 10
    • 0028145249 scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model
    • Miller JW, Adamis AP, Shima DT et al. Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model. Am J Pathol 1994; 145: 574-84.
    • (1994) Am. J. Pathol. , vol.145 , pp. 574-584
    • Miller, J.W.1    Adamis, A.P.2    Shima, D.T.3
  • 11
    • 7844220231 scopus 로고    scopus 로고
    • Upregulation of retinal vascular endothelial growth factor mRNAs in spontaneously diabetic rats without ophthalmoscopic retinopathy: A possible participation of advanced glycation end products in the development of the early phase of diabetic retinopathy
    • Segawa Y, Shirao Y, Yamagishi S et al. Upregulation of retinal vascular endothelial growth factor mRNAs in spontaneously diabetic rats without ophthalmoscopic retinopathy: a possible participation of advanced glycation end products in the development of the early phase of diabetic retinopathy. Ophthalmic Res 1998; 30 333-9.
    • (1998) Ophthalmic Res. , vol.30 , pp. 333-339
    • Segawa, Y.1    Shirao, Y.2    Yamagishi, S.3
  • 12
    • 0030844479 scopus 로고    scopus 로고
    • Transgenic mice with increased expression of vascular endothelial growth factor in the retina: A new model of intraretinal and subretinal neovascularization
    • Okamoto N, Tobe T, Hackett SF et al. Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization. Am J Pathol 1997; 151: 281-91.
    • (1997) Am. J. Pathol. , vol.151 , pp. 281-291
    • Okamoto, N.1    Tobe, T.2    Hackett, S.F.3
  • 13
    • 0033771172 scopus 로고    scopus 로고
    • Choroidal neovascularization in the rat induced by adenovirus mediated expression of vascular endothelial growth factor
    • Baffi J, Byrnes G, Chan CC, Csaky KG. Choroidal neovascularization in the rat induced by adenovirus mediated expression of vascular endothelial growth factor. Invest Ophthalmol Vis Sci 2000; 41: 3582-9.
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , pp. 3582-3589
    • Baffi, J.1    Byrnes, G.2    Chan, C.C.3    Csaky, K.G.4
  • 14
    • 0033882695 scopus 로고    scopus 로고
    • Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization
    • Spilsbury K, Garrett KL, Shen WY, Constable IJ, Rakoczy PE. Overexpression of vascular endothelial growth factor (VEGF) in the retinal pigment epithelium leads to the development of choroidal neovascularization. Am J Pathol 2000; 157: 135-44.
    • (2000) Am. J. Pathol. , vol.157 , pp. 135-144
    • Spilsbury, K.1    Garrett, K.L.2    Shen, W.Y.3    Constable, I.J.4    Rakoczy, P.E.5
  • 15
    • 0035173448 scopus 로고    scopus 로고
    • Novel mechanism for age-related macular degeneration: An equilibrium shift between the angiogenesis factors VEGF and PEDF
    • Ohno-Matsui K, Morita I, Tombran-Tink J et al. Novel mechanism for age-related macular degeneration: an equilibrium shift between the angiogenesis factors VEGF and PEDF. J Cell Physiol 2001; 189: 323-33.
    • (2001) J. Cell Physiol. , vol.189 , pp. 323-333
    • Ohno-Matsui, K.1    Morita, I.2    Tombran-Tink, J.3
  • 16
    • 0033538517 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor: A potent inhibitor of angiogenesis
    • Dawson DW, Volpert OV, Gillis P et al. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science 1999; 285: 245-8.
    • (1999) Science , vol.285 , pp. 245-248
    • Dawson, D.W.1    Volpert, O.V.2    Gillis, P.3
  • 17
    • 0033233243 scopus 로고    scopus 로고
    • 2 homeostasis by hypoxia-inducible factor 1
    • 2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 1999; 15: 551-78.
    • (1999) Annu. Rev. Cell Dev. Biol. , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 18
    • 0034057988 scopus 로고    scopus 로고
    • Laser treatment and the mechanism of edema reduction in branch retinal vein occlusion
    • Arnarsson A, Stefansson E. Laser treatment and the mechanism of edema reduction in branch retinal vein occlusion. Invest Ophthalmol Vis Sci 2000; 41: 877-9.
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41 , pp. 877-879
    • Arnarsson, A.1    Stefansson, E.2
  • 19
    • 0036977250 scopus 로고    scopus 로고
    • The microarray: Potential applications for ophthalmic research
    • Wilson AS, Hobbs BG, Speed TP, Rakoczy PE. The microarray: potential applications for ophthalmic research. Mol Vis 2002; 8 259-70.
    • (2002) Mol. Vis. , vol.8 , pp. 259-270
    • Wilson, A.S.1    Hobbs, B.G.2    Speed, T.P.3    Rakoczy, P.E.4
  • 20
    • 0033995123 scopus 로고    scopus 로고
    • Lutetium texaphyrin (Lu-Tex): A potential new agent for ocular fundus angiography and photodynamic therapy
    • Blumenkranz MS, Woodburn KW, Qing F, Verdooner S, Kessel D, Miller R. Lutetium texaphyrin (Lu-Tex): a potential new agent for ocular fundus angiography and photodynamic therapy. Am J Ophthalmol 2000; 129: 353-62.
    • (2000) Am. J. Ophthalmol. , vol.129 , pp. 353-362
    • Blumenkranz, M.S.1    Woodburn, K.W.2    Qing, F.3    Verdooner, S.4    Kessel, D.5    Miller, R.6
  • 21
    • 0033400593 scopus 로고    scopus 로고
    • Photodynamic therapy with verteporfin is effective for selected patients with neovascular age-related macular degeneration
    • Fine SL. Photodynamic therapy with verteporfin is effective for selected patients with neovascular age-related macular degeneration. Arch Ophthalmol 1999; 117: 1400-2.
    • (1999) Arch. Ophthalmol. , vol.117 , pp. 1400-1402
    • Fine, S.L.1
  • 22
    • 0032823086 scopus 로고    scopus 로고
    • Effects of photodynamic therapy using verteporfin on experimental choroidal neovascularization and normal retina and choroid up to 7 weeks after treatment
    • Husain D, Kramer M, Kenny AG et al. Effects of photodynamic therapy using verteporfin on experimental choroidal neovascularization and normal retina and choroid up to 7 weeks after treatment. Invest Ophthalmol Vis Sci 1999; 40: 2322-31.
    • (1999) Invest. Ophthalmol. Vis. Sci. , vol.40 , pp. 2322-2331
    • Husain, D.1    Kramer, M.2    Kenny, A.G.3
  • 23
    • 0032248010 scopus 로고    scopus 로고
    • Photophysical properties of tin ethyl etiopurpurin I (SnET2) and tin octaethylbenzochlorin (SnOEBC) in solution and bound to albumin
    • Pogue BW, Redmond RW, Trivedi N, Hasan T. Photophysical properties of tin ethyl etiopurpurin I (SnET2) and tin octaethylbenzochlorin (SnOEBC) in solution and bound to albumin. Photochem Photobiol 1998; 68: 809-15.
    • (1998) Photochem. Photobiol. , vol.68 , pp. 809-815
    • Pogue, B.W.1    Redmond, R.W.2    Trivedi, N.3    Hasan, T.4
  • 24
    • 0032750920 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: Insight into mechanisms and implications for cancer growth and ulcer healing
    • Jones MK, Wang H, Peskar BM et al. Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. Nat Med 1999; 5: 1418-23.
    • (1999) Nat. Med. , vol.5 , pp. 1418-1423
    • Jones, M.K.1    Wang, H.2    Peskar, B.M.3
  • 25
    • 0033391630 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors suppress angiogenesis and reduce tumor growth in vivo
    • Sawaoka H, Tsuji S, Tsujii M et al. Cyclooxygenase inhibitors suppress angiogenesis and reduce tumor growth in vivo. Lab Invest 1999; 79: 1469-77.
    • (1999) Lab. Invest , vol.79 , pp. 1469-1477
    • Sawaoka, H.1    Tsuji, S.2    Tsujii, M.3
  • 26
    • 0030067257 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate
    • Adamis AP, Shima DT, Tolentino MJ et al. Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate. Arch Ophthalmol 1996; 114: 66-71.
    • (1996) Arch. Ophthalmol. , vol.114 , pp. 66-71
    • Adamis, A.P.1    Shima, D.T.2    Tolentino, M.J.3
  • 27
    • 0036129304 scopus 로고    scopus 로고
    • Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment
    • Krzystolik MG, Afshari MA, Adamis AP et al. Prevention of experimental choroidal neovascularization with intravitreal anti-vascular endothelial growth factor antibody fragment. Arch Ophthalmol 2002; 120: 338-46.
    • (2002) Arch. Ophthalmol. , vol.120 , pp. 338-346
    • Krzystolik, M.G.1    Afshari, M.A.2    Adamis, A.P.3
  • 28
    • 0028786651 scopus 로고
    • Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins
    • Aiello LP, Pierce EA, Foley ED et al. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci USA 1995; 92: 10457-61.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10457-10461
    • Aiello, L.P.1    Pierce, E.A.2    Foley, E.D.3
  • 29
    • 0035956869 scopus 로고    scopus 로고
    • Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor
    • Stellmach V, Crawford SE, Zhou W, Bouck N. Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor. Proc Natl Acad Sci USA 2001; 98: 2593-7.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2593-2597
    • Stellmach, V.1    Crawford, S.E.2    Zhou, W.3    Bouck, N.4
  • 30
    • 0036798747 scopus 로고    scopus 로고
    • Inhibition of retinal neovascularization by intraocular viral-mediated delivery of anti-angiogenic agents
    • Auricchio A, Behling KC, Maguire AM et al. Inhibition of retinal neovascularization by intraocular viral-mediated delivery of anti-angiogenic agents. Mol Ther 2002; 6: 490-4.
    • (2002) Mol. Ther. , vol.6 , pp. 490-494
    • Auricchio, A.1    Behling, K.C.2    Maguire, A.M.3
  • 31
    • 0034919401 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by adenovirus-mediated sFlt-1 expression in a rat model of corneal neovascularization
    • Lai CM, Brankov M, Zaknich T et al. Inhibition of angiogenesis by adenovirus-mediated sFlt-1 expression in a rat model of corneal neovascularization. Hum Gene Ther 2001; 12: 1299-310.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 1299-1310
    • Lai, C.M.1    Brankov, M.2    Zaknich, T.3
  • 32
    • 0036931209 scopus 로고    scopus 로고
    • Inhibition of corneal neovascularization by recombinant adenovirus mediated antisense VEGF RNA
    • Lai CM, Spilsbury K, Brankov M, Zaknich T, Rakoczy PE. Inhibition of corneal neovascularization by recombinant adenovirus mediated antisense VEGF RNA. Exp Eye Res 2002; 75: 625-34.
    • (2002) Exp. Eye Res. , vol.75 , pp. 625-634
    • Lai, C.M.1    Spilsbury, K.2    Brankov, M.3    Zaknich, T.4    Rakoczy, P.E.5
  • 33
    • 0035404544 scopus 로고    scopus 로고
    • Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin
    • Mori K, Ando A, Gehlbach P et al. Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin. Am J Pathol 2001; 159 313-20.
    • (2001) Am. J. Pathol. , vol.159 , pp. 313-320
    • Mori, K.1    Ando, A.2    Gehlbach, P.3
  • 34
    • 0036271989 scopus 로고    scopus 로고
    • AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization
    • Mori K, Gehlbach P, Yamamoto S et al. AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. Invest Ophthalmol Vis Sci 2002; 43: 1994-2000.
    • (2002) Invest. Ophthalmol. Vis. Sci. , vol.43 , pp. 1994-2000
    • Mori, K.1    Gehlbach, P.2    Yamamoto, S.3
  • 35
    • 10744233606 scopus 로고    scopus 로고
    • Chance or necessity? Insertional mutagenesis in gene therapy and its consequences
    • Baum C, von Kalle C, Staal FJ et al. Chance or necessity? Insertional mutagenesis in gene therapy and its consequences. Mol Ther 2004; 9: 5-13.
    • (2004) Mol. Ther. , vol.9 , pp. 5-13
    • Baum, C.1    von Kalle, C.2    Staal, F.J.3
  • 38
    • 0034980123 scopus 로고    scopus 로고
    • Prospective study of zinc intake and the risk of age-related macular degeneration
    • Cho E, Stampfer MJ, Seddon JM et al. Prospective study of zinc intake and the risk of age-related macular degeneration. Ann Epidemiol 2001; 11: 328-36.
    • (2001) Ann. Epidemiol. , vol.11 , pp. 328-336
    • Cho, E.1    Stampfer, M.J.2    Seddon, J.M.3
  • 39
    • 0036171987 scopus 로고    scopus 로고
    • Can high-dose supplementation with vitamins C and E, beta carotene, and zinc slow the progression of macular degeneration?
    • Gordon JE, Schooff M. Can high-dose supplementation with vitamins C and E, beta carotene, and zinc slow the progression of macular degeneration? J Fam Pract 2002; 51: 105.
    • (2002) J. Fam. Pract. , vol.51 , pp. 105
    • Gordon, J.E.1    Schooff, M.2
  • 40
    • 1842505395 scopus 로고    scopus 로고
    • Cost utility of screening and treatment for early age related macular degeneration with zinc and antioxidants
    • Hopley C, Salkeld G, Wang JJ, Mitchell P. Cost utility of screening and treatment for early age related macular degeneration with zinc and antioxidants. Br J Ophthalmol 2004; 88: 450-4.
    • (2004) Br. J. Ophthalmol. , vol.88 , pp. 450-454
    • Hopley, C.1    Salkeld, G.2    Wang, J.J.3    Mitchell, P.4
  • 41
    • 0017670013 scopus 로고
    • Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation
    • Paterson BM, Roberts BE, Kuff EL. Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation. Proc Natl Acad Sci USA 1977; 74: 4370-4.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 4370-4374
    • Paterson, B.M.1    Roberts, B.E.2    Kuff, E.L.3
  • 43
    • 0026721173 scopus 로고
    • Therapeutic applications of oligonucleotides
    • Crooke ST. Therapeutic applications of oligonucleotides. Annu Rev Pharmacol Toxicol 1992; 32: 329-76.
    • (1992) Annu. Rev. Pharmacol. Toxicol. , vol.32 , pp. 329-376
    • Crooke, S.T.1
  • 44
    • 0344012459 scopus 로고    scopus 로고
    • Thermodynamic criteria for high hit rate antisense oligonucleotide design
    • Matveeva OV, Mathews DH, Tsodikov AD et al. Thermodynamic criteria for high hit rate antisense oligonucleotide design. Nucleic Acids Res 2003; 31: 4989-94.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 4989-4994
    • Matveeva, O.V.1    Mathews, D.H.2    Tsodikov, A.D.3
  • 45
    • 0037938685 scopus 로고    scopus 로고
    • Do natural DNA triple-helical structures occur and function in vivo?
    • Zain R, Sun JS. Do natural DNA triple-helical structures occur and function in vivo? Cell Mol Life Sci 2003; 60: 862-70.
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 862-870
    • Zain, R.1    Sun, J.S.2
  • 46
    • 0026019599 scopus 로고
    • Formation of DNA triplexes accounts for arrests of DNA synthesis at d(TC)n and d(GA)n tracts
    • Baran N, Lapidot A, Manor H. Formation of DNA triplexes accounts for arrests of DNA synthesis at d(TC)n and d(GA)n tracts. Proc Natl Acad Sci USA 1991; 88: 507-11.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 507-511
    • Baran, N.1    Lapidot, A.2    Manor, H.3
  • 47
    • 0028356898 scopus 로고
    • Inhibition of Klenow fragment DNA polymerase on double-helical templates by oligonucleotide-directed triple-helix formation
    • Hacia JG, Dervan PB, Wold BJ. Inhibition of Klenow fragment DNA polymerase on double-helical templates by oligonucleotide-directed triple-helix formation. Biochemistry 1994; 33: 6192-200.
    • (1994) Biochemistry , vol.33 , pp. 6192-6200
    • Hacia, J.G.1    Dervan, P.B.2    Wold, B.J.3
  • 49
    • 0028151352 scopus 로고
    • Trapping DNA polymerases using triplex-forming oligodeoxyribonucleotides
    • Samadashwily GM, Mirkin SM. Trapping DNA polymerases using triplex-forming oligodeoxyribonucleotides. Gene 1994; 149: 127-36.
    • (1994) Gene , vol.149 , pp. 127-136
    • Samadashwily, G.M.1    Mirkin, S.M.2
  • 52
  • 53
    • 0037211937 scopus 로고    scopus 로고
    • Sense oligonucleotide competition for gene promoter binding and activation
    • Cutroneo KR, Chiu JF. Sense oligonucleotide competition for gene promoter binding and activation. Int J Biochem Cell Biol 2003; 35: 32-8.
    • (2003) Int. J. Biochem. Cell Biol. , vol.35 , pp. 32-38
    • Cutroneo, K.R.1    Chiu, J.F.2
  • 54
    • 0001611720 scopus 로고    scopus 로고
    • Dual blockade of cyclic AMP response element-(CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide: Gene-specific inhibition of tumor growth
    • Park YG, Nesterova M, Agrawal S, Cho-Chung YS. Dual blockade of cyclic AMP response element-(CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide: gene-specific inhibition of tumor growth. J Biol Chem 1999; 274: 1573-80.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1573-1580
    • Park, Y.G.1    Nesterova, M.2    Agrawal, S.3    Cho-Chung, Y.S.4
  • 55
    • 0028797651 scopus 로고
    • Inhibition of HSV-1 proliferation by decoy phosphodiester oligonucleotides containing ICP4 recognition sequences
    • Clusel C, Meguenni S, Elias I, Vasseur M, Blumenfeld M. Inhibition of HSV-1 proliferation by decoy phosphodiester oligonucleotides containing ICP4 recognition sequences. Gene Expr 1995; 4: 301-9.
    • (1995) Gene Expr. , vol.4 , pp. 301-309
    • Clusel, C.1    Meguenni, S.2    Elias, I.3    Vasseur, M.4    Blumenfeld, M.5
  • 56
    • 0029031549 scopus 로고
    • A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo
    • Morishita R, Gibbons GH, Horiuchi M et al. A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. Proc Natl Acad Sci USA 1995; 92: 5855-9.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5855-5859
    • Morishita, R.1    Gibbons, G.H.2    Horiuchi, M.3
  • 57
    • 0030707859 scopus 로고    scopus 로고
    • A novel strategy for gene therapy and gene regulation analysis using transcription factor decoy oligonucleotides
    • Tomita N, Morishita R, Higaki J, Ogihara T. A novel strategy for gene therapy and gene regulation analysis using transcription factor decoy oligonucleotides. Exp Nephrol 1997; 5: 429-34.
    • (1997) Exp. Nephrol. , vol.5 , pp. 429-434
    • Tomita, N.1    Morishita, R.2    Higaki, J.3    Ogihara, T.4
  • 58
    • 0038814156 scopus 로고    scopus 로고
    • Development of novel decoy oligonucleotides: Advantages of circular dumb-bell decoy
    • Tomita N, Tomita T, Yuyama K et al. Development of novel decoy oligonucleotides: advantages of circular dumb-bell decoy. Curr Opin Mol Ther 2003; 5: 107-12.
    • (2003) Curr. Opin. Mol. Ther. , vol.5 , pp. 107-112
    • Tomita, N.1    Tomita, T.2    Yuyama, K.3
  • 59
    • 0003084359 scopus 로고    scopus 로고
    • Structure, recognition and discrimination in RNA aptamer complexes with cofactors, amino acids, drugs and aminoglycoside antibiotics
    • Patel DJ, Suri AK. Structure, recognition and discrimination in RNA aptamer complexes with cofactors, amino acids, drugs and aminoglycoside antibiotics. J Biotechnol 2000; 74: 39-60.
    • (2000) J. Biotechnol. , vol.74 , pp. 39-60
    • Patel, D.J.1    Suri, A.K.2
  • 60
    • 0031563817 scopus 로고    scopus 로고
    • Structure, recognition and adaptive binding in RNA aptamer complexes
    • Patel DJ, Suri AK, Jiang F et al. Structure, recognition and adaptive binding in RNA aptamer complexes. J Mol Biol 1997; 272: 645-64.
    • (1997) J. Mol. Biol. , vol.272 , pp. 645-664
    • Patel, D.J.1    Suri, A.K.2    Jiang, F.3
  • 62
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington AD, Szostak JW. In vitro selection of RNA molecules that bind specific ligands. Nature 1990; 346: 818-22.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 63
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk C, Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 1990; 249: 505-10.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 64
    • 0141854224 scopus 로고    scopus 로고
    • RNA interference: From an ancient mechanism to a state of the art therapeutic application?
    • Arenz C, Schepers U. RNA interference: from an ancient mechanism to a state of the art therapeutic application? Naturwissenschaften 2003; 90: 345-59.
    • (2003) Naturwissenschaften , vol.90 , pp. 345-359
    • Arenz, C.1    Schepers, U.2
  • 65
    • 0005772676 scopus 로고
    • Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide
    • Stephenson ML, Zamecnik PC. Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc Natl Acad Sci USA 1978; 75: 285-8.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 285-288
    • Stephenson, M.L.1    Zamecnik, P.C.2
  • 66
    • 0041582974 scopus 로고
    • Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
    • Zamecnik PC, Stephenson ML. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc Natl Acad Sci USA 1978; 75: 280-4.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 280-284
    • Zamecnik, P.C.1    Stephenson, M.L.2
  • 69
    • 0036846993 scopus 로고    scopus 로고
    • Antisense therapy for cancer: The time of truth
    • Jansen B, Zangemeister-Wittke U. Antisense therapy for cancer: the time of truth. Lancet Oncol 2002; 3: 672-83.
    • (2002) Lancet Oncol. , vol.3 , pp. 672-683
    • Jansen, B.1    Zangemeister-Wittke, U.2
  • 70
    • 0027216834 scopus 로고
    • Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region
    • Azad RF, Driver VB, Tanaka K, Crooke RM, Anderson KP. Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region. Antimicrob Agents Chemother 1993; 37: 1945-54.
    • (1993) Antimicrob. Agents Chemother. , vol.37 , pp. 1945-1954
    • Azad, R.F.1    Driver, V.B.2    Tanaka, K.3    Crooke, R.M.4    Anderson, K.P.5
  • 71
    • 0036202668 scopus 로고    scopus 로고
    • A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with AIDS
    • Group TVS. A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with AIDS. Am J Ophthalmol 2002; 133: 467-74.
    • (2002) Am. J. Ophthalmol. , vol.133 , pp. 467-474
    • Group, T.V.S.1
  • 72
    • 0036211366 scopus 로고    scopus 로고
    • Randomized dose-comparison studies of intravitreous fomivirsen for treatment of cytomegalovirus retinitis that has reactivated or is persistently active despite other therapies in patients with AIDS
    • Group TVS. Randomized dose-comparison studies of intravitreous fomivirsen for treatment of cytomegalovirus retinitis that has reactivated or is persistently active despite other therapies in patients with AIDS. Am J Ophthalmol 2002; 133: 475-83.
    • (2002) Am. J. Ophthalmol. , vol.133 , pp. 475-483
    • Group, T.V.S.1
  • 73
    • 0036202847 scopus 로고    scopus 로고
    • Safety of intravitreous fomivirsen for treatment of cytomegalovirus retinitis in patients with AIDS
    • Group TVS. Safety of intravitreous fomivirsen for treatment of cytomegalovirus retinitis in patients with AIDS. Am J Ophthalmol 2002; 133: 484-98.
    • (2002) Am. J. Ophthalmol. , vol.133 , pp. 484-498
    • Group, T.V.S.1
  • 74
    • 0035407426 scopus 로고    scopus 로고
    • In vivo use of oligonucleotides to inhibit choroidal neovascularisation in the eye
    • Garrett KL, Shen WY, Rakoczy PE. In vivo use of oligonucleotides to inhibit choroidal neovascularisation in the eye. J Gene Med 2001; 3: 373-83.
    • (2001) J. Gene Med. , vol.3 , pp. 373-383
    • Garrett, K.L.1    Shen, W.Y.2    Rakoczy, P.E.3
  • 75
    • 0037119744 scopus 로고    scopus 로고
    • Syntheses of polycationic dendrimers on lipophilic peptide core for complexation and transport of oligonucleotides
    • Wimmer N, Marano RJ, Kearns PS, Rakoczy PE, Toth I. Syntheses of polycationic dendrimers on lipophilic peptide core for complexation and transport of oligonucleotides. Bioorg Med Chem Lett 2002; 12 2635-7.
    • (2002) Bioorg. Med. Chem. Lett. , vol.12 , pp. 2635-2637
    • Wimmer, N.1    Marano, R.J.2    Kearns, P.S.3    Rakoczy, P.E.4    Toth, I.5
  • 76
    • 0032493654 scopus 로고    scopus 로고
    • 2′-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165): Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
    • Ruckman J, Green LS, Beeson J et al. 2′-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165): inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain. J Biol Chem 1998; 273: 20556-67.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20556-20567
    • Ruckman, J.1    Green, L.S.2    Beeson, J.3
  • 78
    • 1242297011 scopus 로고    scopus 로고
    • Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal neovascularization
    • Tolentino MJ, Brucker AJ, Fosnot J et al. Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal neovascularization. Retina 2004; 24: 132-8.
    • (2004) Retina , vol.24 , pp. 132-138
    • Tolentino, M.J.1    Brucker, A.J.2    Fosnot, J.3
  • 79
    • 1342272496 scopus 로고    scopus 로고
    • Comparative effects of two synthetic oligosaccharides on platelet activation induced by plasma from HIT patients
    • Savi P, Pflieger AM, Herault JP et al. Comparative effects of two synthetic oligosaccharides on platelet activation induced by plasma from HIT patients. J Thromb Haemost 2003; 1: 2008-13.
    • (2003) J. Thromb. Haemost. , vol.1 , pp. 2008-2013
    • Savi, P.1    Pflieger, A.M.2    Herault, J.P.3
  • 80
    • 0037373763 scopus 로고    scopus 로고
    • Structural modifications of antisense oligonucleotides
    • Urban E, Noe CR. Structural modifications of antisense oligonucleotides. Farmaco 2003; 58: 243-58.
    • (2003) Farmaco , vol.58 , pp. 243-258
    • Urban, E.1    Noe, C.R.2
  • 81
    • 0027376439 scopus 로고
    • Antisense oligonucleotides as therapeutic agents: Is the bullet really magical?
    • Stein CA, Cheng YC. Antisense oligonucleotides as therapeutic agents: is the bullet really magical? Science 1993; 261: 1004-12.
    • (1993) Science , vol.261 , pp. 1004-1012
    • Stein, C.A.1    Cheng, Y.C.2
  • 82
    • 0037335318 scopus 로고    scopus 로고
    • The impact of nucleic acid secondary structure on PNA hybridization
    • Armitage BA. The impact of nucleic acid secondary structure on PNA hybridization. Drug Discov Today 2003; 8: 222-8.
    • (2003) Drug Discov. Today , vol.8 , pp. 222-228
    • Armitage, B.A.1
  • 83
    • 0029839291 scopus 로고    scopus 로고
    • Targeted delivery of an antisense oligonucleotide in the retina: Uptake, distribution, stability, and effect
    • Rakoczy PE, Lai MC, Watson M, Seydel U, Constable I. Targeted delivery of an antisense oligonucleotide in the retina: uptake, distribution, stability, and effect. Antisense Nucleic Acid Drug Dev 1996; 6: 207-13.
    • (1996) Antisense Nucleic Acid Drug Dev. , vol.6 , pp. 207-213
    • Rakoczy, P.E.1    Lai, M.C.2    Watson, M.3    Seydel, U.4    Constable, I.5
  • 84
    • 0034850264 scopus 로고    scopus 로고
    • Uptake dynamics and retinal tolerance of phosphorothioate oligonucleotide and its direct delivery into the site of choroidal neovascularization through subretinal administration in the rat
    • Shen WY, Rakoczy PE. Uptake dynamics and retinal tolerance of phosphorothioate oligonucleotide and its direct delivery into the site of choroidal neovascularization through subretinal administration in the rat. Antisense Nucleic Acid Drug Dev 2001; 11: 257-64.
    • (2001) Antisense Nucleic Acid Drug Dev. , vol.11 , pp. 257-264
    • Shen, W.Y.1    Rakoczy, P.E.2
  • 85
    • 0038782333 scopus 로고    scopus 로고
    • Targeted delivery system for antisense oligonucleotides: A novel experimental strategy for neuroblastoma treatment
    • Brignole C, Pagnan G, Marimpietri D et al. Targeted delivery system for antisense oligonucleotides: a novel experimental strategy for neuroblastoma treatment. Cancer Lett 2003; 197: 231-5.
    • (2003) Cancer Lett. , vol.197 , pp. 231-235
    • Brignole, C.1    Pagnan, G.2    Marimpietri, D.3
  • 86
    • 0036131650 scopus 로고    scopus 로고
    • The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides
    • Chirila TV, Rakoczy PE, Garrett KL, Lou X, Constable IJ. The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides. Biomaterials 2002; 23: 321-42.
    • (2002) Biomaterials , vol.23 , pp. 321-342
    • Chirila, T.V.1    Rakoczy, P.E.2    Garrett, K.L.3    Lou, X.4    Constable, I.J.5
  • 90
    • 0043212038 scopus 로고    scopus 로고
    • Innovations in oligonucleotide drug delivery
    • Lysik MA, Wu-Pong S. Innovations in oligonucleotide drug delivery. J Pharm Sci 2003; 92: 1559-73.
    • (2003) J. Pharm. Sci. , vol.92 , pp. 1559-1573
    • Lysik, M.A.1    Wu-Pong, S.2
  • 91
    • 0031772763 scopus 로고    scopus 로고
    • Antisense oligonucleotides: Strategies for delivery
    • Miller KJ, Das SKU. Antisense oligonucleotides: strategies for delivery. Pharm Sci Technol Today 1998; 1: 377-86.
    • (1998) Pharm. Sci. Technol. Today , vol.1 , pp. 377-386
    • Miller, K.J.1    Das, S.K.U.2
  • 92
    • 0035082648 scopus 로고    scopus 로고
    • Development of gene drug delivery systems based on pharmacokinetic studies
    • Takakura Y, Nishikawa M, Yamashita F, Hashida M. Development of gene drug delivery systems based on pharmacokinetic studies. Eur J Pharm Sci 2001; 13: 71-6.
    • (2001) Eur. J. Pharm. Sci. , vol.13 , pp. 71-76
    • Takakura, Y.1    Nishikawa, M.2    Yamashita, F.3    Hashida, M.4
  • 93
    • 0037600638 scopus 로고    scopus 로고
    • Peptide-mediated cellular delivery of antisense oligonucleotides and their analogues
    • Gait MJ. Peptide-mediated cellular delivery of antisense oligonucleotides and their analogues. Cell Mol Life Sci 2003; 60 844-53.
    • (2003) Cell Mol. Life Sci. , vol.60 , pp. 844-853
    • Gait, M.J.1
  • 94
    • 0033564268 scopus 로고    scopus 로고
    • Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo
    • Biessen EA, Vietsch H, Rump ET et al. Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo. Biochem J 1999; 340: 783-92.
    • (1999) Biochem. J. , vol.340 , pp. 783-792
    • Biessen, E.A.1    Vietsch, H.2    Rump, E.T.3
  • 96
    • 0035904982 scopus 로고    scopus 로고
    • Conditional gene targeting for cancer gene therapy
    • Haviv YS, Curiel DT. Conditional gene targeting for cancer gene therapy. Adv Drug Deliv Rev 2001; 53: 135-54.
    • (2001) Adv. Drug Deliv. Rev. , vol.53 , pp. 135-154
    • Haviv, Y.S.1    Curiel, D.T.2
  • 97
    • 0035181482 scopus 로고    scopus 로고
    • Tumor targeting and imaging of intraperitoneal tumors by use of antisense oligo-DNA complexed with dendrimers and/or avidin in mice
    • Sato N, Kobayashi H, Saga T et al. Tumor targeting and imaging of intraperitoneal tumors by use of antisense oligo-DNA complexed with dendrimers and/or avidin in mice. Clin Cancer Res 2001; 7 3606-12.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 3606-3612
    • Sato, N.1    Kobayashi, H.2    Saga, T.3
  • 98
    • 0038190867 scopus 로고    scopus 로고
    • Magnetofection: A highly efficient tool for antisense oligonucleotide delivery in vitro and in vivo
    • Krotz F, de Wit C, Sohn HY et al. Magnetofection: a highly efficient tool for antisense oligonucleotide delivery in vitro and in vivo. Mol Ther 2003; 7: 700-10.
    • (2003) Mol. Ther. , vol.7 , pp. 700-710
    • Krotz, F.1    de Wit, C.2    Sohn, H.Y.3
  • 99
    • 85047695405 scopus 로고    scopus 로고
    • Magnetofection: Enhancing and targeting gene delivery by magnetic force in vitro and in vivo
    • Scherer F, Anton M, Schillinger U et al. Magnetofection: enhancing and targeting gene delivery by magnetic force in vitro and in vivo. Gene Ther 2002; 9: 102-9.
    • (2002) Gene Ther. , vol.9 , pp. 102-109
    • Scherer, F.1    Anton, M.2    Schillinger, U.3
  • 100
    • 0037453175 scopus 로고    scopus 로고
    • A new delivery system for antisense therapy: PLGA microspheres encapsulating oligonucleotide/polyethyleneimine solid complexes
    • De Rosa G, Bochot A, Quaglia F, Besnard M, Fattal E. A new delivery system for antisense therapy: PLGA microspheres encapsulating oligonucleotide/polyethyleneimine solid complexes. Int J Pharm 2003; 254: 89-93.
    • (2003) Int. J. Pharm. , vol.254 , pp. 89-93
    • De Rosa, G.1    Bochot, A.2    Quaglia, F.3    Besnard, M.4    Fattal, E.5
  • 101
    • 0037151441 scopus 로고    scopus 로고
    • Biodegradable microparticles for the controlled delivery of oligonucleotides
    • De Rosa G, Quaglia F, La Rotonda M, Besnard M, Fattal E. Biodegradable microparticles for the controlled delivery of oligonucleotides. Int J Pharm 2002; 242: 225-8.
    • (2002) Int. J. Pharm. , vol.242 , pp. 225-228
    • De Rosa, G.1    Quaglia, F.2    La Rotonda, M.3    Besnard, M.4    Fattal, E.5


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