메뉴 건너뛰기




Volumn 8, Issue 5, 2003, Pages 222-228

The impact of nucleic acid secondary structure on PNA hybridization

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; OLIGOMER; PEPTIDE NUCLEIC ACID;

EID: 0037335318     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(03)02611-4     Document Type: Review
Times cited : (76)

References (69)
  • 1
    • 0038497542 scopus 로고
    • A structure for deoxyribose nucleic acid
    • Watson J.D., Crick F.H.C. A structure for deoxyribose nucleic acid. Nature. 171:1953;737-738.
    • (1953) Nature , vol.171 , pp. 737-738
    • Watson, J.D.1    Crick, F.H.C.2
  • 2
    • 0026341239 scopus 로고
    • Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide
    • Nielsen P.E., et al. Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science. 254:1991;1498-1500.
    • (1991) Science , vol.254 , pp. 1498-1500
    • Nielsen, P.E.1
  • 3
    • 0344054679 scopus 로고    scopus 로고
    • Peptide nucleic acid (PNA). A DNA mimic with a pseudopeptide backbone
    • Nielsen P.E., Haaima G. Peptide nucleic acid (PNA). A DNA mimic with a pseudopeptide backbone. Chem. Soc. Rev. 26:1997;73-78.
    • (1997) Chem. Soc. Rev. , vol.26 , pp. 73-78
    • Nielsen, P.E.1    Haaima, G.2
  • 4
    • 0032476790 scopus 로고    scopus 로고
    • PNA: Synthetic polyamide nucleic acids with unusual binding properties
    • Uhlmann E., et al. PNA: synthetic polyamide nucleic acids with unusual binding properties. Angew. Chem. Int. Ed. 37:1998;2796-2823.
    • (1998) Angew. Chem. Int. Ed. , vol.37 , pp. 2796-2823
    • Uhlmann, E.1
  • 5
    • 0027364174 scopus 로고
    • PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules
    • Egholm M., et al. PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature. 365:1993;566-568.
    • (1993) Nature , vol.365 , pp. 566-568
    • Egholm, M.1
  • 6
    • 33644477832 scopus 로고
    • Peptide nucleic acids (PNA). Oligonucleotide analogues with an achiral peptide backbone
    • Egholm M., et al. Peptide nucleic acids (PNA). Oligonucleotide analogues with an achiral peptide backbone. J. Am. Chem. Soc. 114:1992;1895-1897.
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 1895-1897
    • Egholm, M.1
  • 7
    • 0034852682 scopus 로고    scopus 로고
    • Sequence-specific targeting of duplex DNA by peptide nucleic acids via triplex strand invasion
    • Demidov V.V., Frank-Kamenetskii M.D. Sequence-specific targeting of duplex DNA by peptide nucleic acids via triplex strand invasion. Methods. 23:2001;108-122.
    • (2001) Methods , vol.23 , pp. 108-122
    • Demidov, V.V.1    Frank-Kamenetskii, M.D.2
  • 8
    • 0028175775 scopus 로고
    • Peptide nucleic acid. DNA strand displacement loops as artificial transcription promoters
    • Møllegaard N.E., et al. Peptide nucleic acid. DNA strand displacement loops as artificial transcription promoters. Proc. Natl. Acad. Sci. U. S. A. 91:1994;3892-3895.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 3892-3895
    • Møllegaard, N.E.1
  • 9
    • 0035834454 scopus 로고    scopus 로고
    • Defining the peptide nucleic acids (PNA) length requirement for PNA binding-induced transcription and gene expression
    • Wang G., et al. Defining the peptide nucleic acids (PNA) length requirement for PNA binding-induced transcription and gene expression. J. Mol. Biol. 313:2001;933-940.
    • (2001) J. Mol. Biol. , vol.313 , pp. 933-940
    • Wang, G.1
  • 10
    • 0037028920 scopus 로고    scopus 로고
    • Toward synthetic transcription activators: Recruitment of transcription factors to DNA by a PNA-peptide chimera
    • Liu B., et al. Toward synthetic transcription activators: recruitment of transcription factors to DNA by a PNA-peptide chimera. J. Am. Chem. Soc. 124:2002;1838-1839.
    • (2002) J. Am. Chem. Soc. , vol.124 , pp. 1838-1839
    • Liu, B.1
  • 11
    • 0033607615 scopus 로고    scopus 로고
    • Antisense PNA tridecamers targeted to the coding region of Ha-ras mRNA arrest polypeptide chain elongation
    • Dias N., et al. Antisense PNA tridecamers targeted to the coding region of Ha-ras mRNA arrest polypeptide chain elongation. J. Mol. Biol. 294:1999;403-416.
    • (1999) J. Mol. Biol. , vol.294 , pp. 403-416
    • Dias, N.1
  • 12
    • 0035830450 scopus 로고    scopus 로고
    • Inhibition of gene expression inside cells by peptide nucleic acids: Effect of mRNA target sequence, mismatched bases, and PNA length
    • Doyle D.F., et al. Inhibition of gene expression inside cells by peptide nucleic acids: effect of mRNA target sequence, mismatched bases, and PNA length. Biochemistry. 40:2001;53-64.
    • (2001) Biochemistry , vol.40 , pp. 53-64
    • Doyle, D.F.1
  • 13
    • 0036314340 scopus 로고    scopus 로고
    • RNA hairpin invasion and ribosome elongation arrest by mixed base PNA oligomer
    • Dias N., et al. RNA hairpin invasion and ribosome elongation arrest by mixed base PNA oligomer. J. Mol. Biol. 320:2002;489-501.
    • (2002) J. Mol. Biol. , vol.320 , pp. 489-501
    • Dias, N.1
  • 14
    • 0031979354 scopus 로고    scopus 로고
    • Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA
    • Good L., Nielsen P.E. Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA. Nat. Biotechnol. 16:1998;355-358.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 355-358
    • Good, L.1    Nielsen, P.E.2
  • 15
    • 0035075441 scopus 로고    scopus 로고
    • Bactericidal antisense effects of peptide-PNA conjugates
    • Good L., et al. Bactericidal antisense effects of peptide-PNA conjugates. Nat. Biotechnol. 19:2001;360-364.
    • (2001) Nat. Biotechnol. , vol.19 , pp. 360-364
    • Good, L.1
  • 17
    • 13344293719 scopus 로고    scopus 로고
    • PNA as a rare genome-cutter
    • Veselkov A.G., et al. PNA as a rare genome-cutter. Nature. 379:1996;214.
    • (1996) Nature , vol.379 , pp. 214
    • Veselkov, A.G.1
  • 18
    • 0029989057 scopus 로고    scopus 로고
    • A new class of genome rare cutters
    • Veselkov A.G., et al. A new class of genome rare cutters. Nucleic Acids Res. 24:1996;2483-2488.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2483-2488
    • Veselkov, A.G.1
  • 20
    • 0034609587 scopus 로고    scopus 로고
    • Sequence-specific protection of duplex DNA against restriction and methylation enzymes by pseudocomplementary PNAs
    • Izvolsky K.I., et al. Sequence-specific protection of duplex DNA against restriction and methylation enzymes by pseudocomplementary PNAs. Biochemistry. 39:2000;10908-10913.
    • (2000) Biochemistry , vol.39 , pp. 10908-10913
    • Izvolsky, K.I.1
  • 21
    • 0029162624 scopus 로고
    • Sequence-specific purification of nucleic acids by PNA-controlled hybrid selection
    • Ørum H., et al. Sequence-specific purification of nucleic acids by PNA-controlled hybrid selection. Biotechniques. 19:1995;472-480.
    • (1995) Biotechniques , vol.19 , pp. 472-480
    • Ørum, H.1
  • 22
    • 0032958001 scopus 로고    scopus 로고
    • Gene chemistry: Functionally and conformationally intact fluorescent plasmid DNA
    • Zelphati O., et al. Gene chemistry: functionally and conformationally intact fluorescent plasmid DNA. Hum. Gene Ther. 10:1999;15-24.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 15-24
    • Zelphati, O.1
  • 23
    • 0028624658 scopus 로고
    • Electron microscopy mapping of oligopurine tracts in duplex DNA by peptide nucleic acid targeting
    • Demidov V.V., et al. Electron microscopy mapping of oligopurine tracts in duplex DNA by peptide nucleic acid targeting. Nucleic Acids Res. 22:1994;5218-5222.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5218-5222
    • Demidov, V.V.1
  • 24
    • 84871947556 scopus 로고    scopus 로고
    • An earring for the double helix: Assembly of topological links comprising duplex DNA and a circular oligodeoxynucleotide
    • Kuhn H., et al. An earring for the double helix: assembly of topological links comprising duplex DNA and a circular oligodeoxynucleotide. J. Biomol. Struct. Dyn. S2:2000;221-225.
    • (2000) J. Biomol. Struct. Dyn. , vol.S2 , pp. 221-225
    • Kuhn, H.1
  • 25
    • 0033964669 scopus 로고    scopus 로고
    • PNA-dependent gene chemistry: Stable coupling of peptides and oligonucleotides to plasmid DNA
    • Zelphati O., et al. PNA-dependent gene chemistry: stable coupling of peptides and oligonucleotides to plasmid DNA. Biotechniques. 28:2000;304-316.
    • (2000) Biotechniques , vol.28 , pp. 304-316
    • Zelphati, O.1
  • 26
    • 0029963160 scopus 로고
    • Strand displacement binding of a duplex-forming homopurine PNA to a homopyrimidine duplex DNA target
    • Nielsen P.E., Christensen L. Strand displacement binding of a duplex-forming homopurine PNA to a homopyrimidine duplex DNA target. J. Am. Chem. Soc. 118:1995;2287-2288.
    • (1995) J. Am. Chem. Soc. , vol.118 , pp. 2287-2288
    • Nielsen, P.E.1    Christensen, L.2
  • 27
    • 0033577352 scopus 로고    scopus 로고
    • Rules for strand invasion by chemically modified oligonucleotides
    • Ishihara T., Corey D.R. Rules for strand invasion by chemically modified oligonucleotides. J. Am. Chem. Soc. 121:1999;2012-2020.
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 2012-2020
    • Ishihara, T.1    Corey, D.R.2
  • 28
    • 0034283848 scopus 로고    scopus 로고
    • Strand invasion by mixed base PNAs and a PNA-peptide chimera
    • Zhang X., et al. Strand invasion by mixed base PNAs and a PNA-peptide chimera. Nucleic Acids Res. 28:2000;3332-3338.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 3332-3338
    • Zhang, X.1
  • 29
    • 0028930189 scopus 로고
    • Kinetics and mechanism of polyamide ('peptide') nucleic acid binding to duplex DNA
    • Demidov V.V., et al. Kinetics and mechanism of polyamide ('peptide') nucleic acid binding to duplex DNA. Proc. Natl. Acad. Sci. U. S. A. 92:1995;2637-2641.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 2637-2641
    • Demidov, V.V.1
  • 30
    • 0033548529 scopus 로고    scopus 로고
    • An experimental study of mechanism and specificity of peptide nucleic acid (PNA) binding to duplex DNA
    • Kuhn H., et al. An experimental study of mechanism and specificity of peptide nucleic acid (PNA) binding to duplex DNA. J. Mol. Biol. 286:1999;1337-1345.
    • (1999) J. Mol. Biol. , vol.286 , pp. 1337-1345
    • Kuhn, H.1
  • 31
    • 0028928953 scopus 로고
    • Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA
    • Egholm M., et al. Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA. Nucleic Acids Res. 23:1995;217-222.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 217-222
    • Egholm, M.1
  • 32
    • 0028848588 scopus 로고
    • Single and bis peptide nucleic acids as triplexing agents: Binding and stoichiometry
    • Griffith M.C., et al. Single and bis peptide nucleic acids as triplexing agents: binding and stoichiometry. J. Am. Chem. Soc. 117:1995;831-832.
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 831-832
    • Griffith, M.C.1
  • 33
    • 0037125964 scopus 로고    scopus 로고
    • Enhanced strand invasion by peptide nucleic acid-peptide conjugates
    • Kaihatsu K., et al. Enhanced strand invasion by peptide nucleic acid-peptide conjugates. Biochemistry. 41:2002;11118-11125.
    • (2002) Biochemistry , vol.41 , pp. 11118-11125
    • Kaihatsu, K.1
  • 34
    • 0032738421 scopus 로고    scopus 로고
    • Double duplex invasion by peptide nucleic acid: A general principle for sequence-specific targeting of double-stranded DNA
    • Lohse J., et al. Double duplex invasion by peptide nucleic acid: A general principle for sequence-specific targeting of double-stranded DNA. Proc. Natl. Acad. Sci. U. S. A. 96:1999;11804-11808.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 11804-11808
    • Lohse, J.1
  • 35
    • 0037197963 scopus 로고    scopus 로고
    • Kinetics and mechanism of the DNA double helix invasion by pseudocomplementary peptide nucleic acids
    • Demidov V.V., et al. Kinetics and mechanism of the DNA double helix invasion by pseudocomplementary peptide nucleic acids. Proc. Natl. Acad. Sci. U. S. A. 99:2002;5953-5958.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 5953-5958
    • Demidov, V.V.1
  • 36
    • 0003472884 scopus 로고    scopus 로고
    • V.N. Soyfer, & V.N. Potaman. Springer-Verlag
    • Soyfer V.N., Potaman V.N. Triple-Helical Nucleic Acids. 1996;Springer-Verlag.
    • (1996) Triple-Helical Nucleic Acids
  • 37
    • 0037015078 scopus 로고    scopus 로고
    • Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
    • Siddiqui-Jain A., et al. Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription. Proc. Natl. Acad. Sci. U. S. A. 99:2002;11593-11598.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 11593-11598
    • Siddiqui-Jain, A.1
  • 38
    • 0035997348 scopus 로고    scopus 로고
    • V(D)J recombination: RAG proteins, repair factors and regulation
    • Gellert M. V(D)J recombination: RAG proteins, repair factors and regulation. Annu. Rev. Biochem. 71:2002;101-132.
    • (2002) Annu. Rev. Biochem. , vol.71 , pp. 101-132
    • Gellert, M.1
  • 39
    • 0035823868 scopus 로고    scopus 로고
    • Effect of secondary structure on the thermodynamics and kinetics of PNA hybridization to DNA hairpins
    • Kushon S.A., et al. Effect of secondary structure on the thermodynamics and kinetics of PNA hybridization to DNA hairpins. J. Am. Chem. Soc. 123:2001;10805-10813.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 10805-10813
    • Kushon, S.A.1
  • 40
    • 0029121733 scopus 로고
    • Exceptionally stable nucleic acid hairpins
    • Varani G. Exceptionally stable nucleic acid hairpins. Annu. Rev. Biophys. Biomol. Struct. 24:1995;379-404.
    • (1995) Annu. Rev. Biophys. Biomol. Struct. , vol.24 , pp. 379-404
    • Varani, G.1
  • 41
    • 0032580965 scopus 로고    scopus 로고
    • Hairpin-forming peptide nucleic acid oligomers
    • Armitage B., et al. Hairpin-forming peptide nucleic acid oligomers. Biochemistry. 37:1998;9417-9425.
    • (1998) Biochemistry , vol.37 , pp. 9417-9425
    • Armitage, B.1
  • 43
    • 0002205687 scopus 로고    scopus 로고
    • Life at the end of the chromosome: Telomeres and telomerase
    • Cech T.R. Life at the end of the chromosome: telomeres and telomerase. Angew. Chem. Int. Ed. Engl. 39:2000;35-43.
    • (2000) Angew. Chem. Int. Ed. Engl. , vol.39 , pp. 35-43
    • Cech, T.R.1
  • 44
    • 0035075342 scopus 로고    scopus 로고
    • Functional and dysfunctional roles of quadruplex DNA in cells
    • Arthanari H., Bolton P.H. Functional and dysfunctional roles of quadruplex DNA in cells. Chem. Biol. 8:2001;221-230.
    • (2001) Chem. Biol. , vol.8 , pp. 221-230
    • Arthanari, H.1    Bolton, P.H.2
  • 45
    • 0035900649 scopus 로고    scopus 로고
    • Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function
    • Darnell J.C., et al. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function. Cell. 107:2001;489-499.
    • (2001) Cell , vol.107 , pp. 489-499
    • Darnell, J.C.1
  • 46
    • 0035964292 scopus 로고    scopus 로고
    • DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity
    • Andreola M-L., et al. DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity. Biochemistry. 40:2001;10087-10094.
    • (2001) Biochemistry , vol.40 , pp. 10087-10094
    • Andreola, M-L.1
  • 47
    • 0027537022 scopus 로고
    • A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA
    • Wang K.Y., et al. A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA. Biochemistry. 32:1993;1899-1904.
    • (1993) Biochemistry , vol.32 , pp. 1899-1904
    • Wang, K.Y.1
  • 48
    • 0034606402 scopus 로고    scopus 로고
    • In vitro selection of hematoporphyrin binding DNA aptamers
    • Okazawa A., et al. In vitro selection of hematoporphyrin binding DNA aptamers. Bioorg. Med. Chem. Lett. 10:2000;2653-2656.
    • (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 2653-2656
    • Okazawa, A.1
  • 49
    • 0037022658 scopus 로고    scopus 로고
    • Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands
    • Riou J.F., et al. Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands. Proc. Natl. Acad. Sci. U. S. A. 99:2002;2672-2677.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 2672-2677
    • Riou, J.F.1
  • 50
    • 0026575221 scopus 로고
    • Selection of single-stranded DNA molecules that bind and inhibit human thrombin
    • Bock L.C., et al. Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature. 355:1992;564-566.
    • (1992) Nature , vol.355 , pp. 564-566
    • Bock, L.C.1
  • 51
    • 0035802357 scopus 로고    scopus 로고
    • Hybridization of PNA to structured DNA targets: Quadruplex invasion and the overhang effect
    • Datta B., Armitage B.A. Hybridization of PNA to structured DNA targets: quadruplex invasion and the overhang effect. J. Am. Chem. Soc. 123:2001;9612-9619.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 9612-9619
    • Datta, B.1    Armitage, B.A.2
  • 52
    • 0030018227 scopus 로고    scopus 로고
    • Ionic effects on the stability and conformation of peptide nucleic acid complexes
    • Tomac S., et al. Ionic effects on the stability and conformation of peptide nucleic acid complexes. J. Am. Chem. Soc. 118:1996;5544-5552.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 5544-5552
    • Tomac, S.1
  • 53
    • 0031953529 scopus 로고    scopus 로고
    • Localization of trinucleotide repeat sequences in myotonic dystrophy cells using a single fluorochrome-labeled PNA probe
    • Taneja K.L. Localization of trinucleotide repeat sequences in myotonic dystrophy cells using a single fluorochrome-labeled PNA probe. Biotechniques. 24:1998;472-476.
    • (1998) Biotechniques , vol.24 , pp. 472-476
    • Taneja, K.L.1
  • 54
    • 0028960198 scopus 로고
    • Isolation of active genes containing CAG repeats by DNA strand invasion by a peptide nucleic acid
    • Boffa L.C., et al. Isolation of active genes containing CAG repeats by DNA strand invasion by a peptide nucleic acid. Proc. Natl. Acad. Sci. U. S. A. 92:1995;1901-1905.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 1901-1905
    • Boffa, L.C.1
  • 55
    • 0030006487 scopus 로고    scopus 로고
    • Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence
    • Boffa L.C., et al. Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence. J. Biol. Chem. 271:1996;13228-13233.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13228-13233
    • Boffa, L.C.1
  • 56
    • 0037069430 scopus 로고    scopus 로고
    • Conformational energetics of stable and metastable states formed by DNA triplet repeat oligonucleotides: Implications for triplet expansion diseases
    • Voelker J., et al. Conformational energetics of stable and metastable states formed by DNA triplet repeat oligonucleotides: implications for triplet expansion diseases. Proc. Natl. Acad. Sci. U. S. A. 99:2002;14700-14705.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 14700-14705
    • Voelker, J.1
  • 57
    • 0033150534 scopus 로고    scopus 로고
    • Cellular delivery of peptide nucleic acids and inhibition of human telomerase
    • Hamilton S.E., et al. Cellular delivery of peptide nucleic acids and inhibition of human telomerase. Chem. Biol. 6:1999;343-351.
    • (1999) Chem. Biol. , vol.6 , pp. 343-351
    • Hamilton, S.E.1
  • 58
    • 0034640463 scopus 로고    scopus 로고
    • Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells
    • Villa R., et al. Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells. FEBS Lett. 473:2000;241-248.
    • (2000) FEBS Lett. , vol.473 , pp. 241-248
    • Villa, R.1
  • 60
    • 0032478330 scopus 로고    scopus 로고
    • Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA
    • Good L., Nielsen P.E. Inhibition of translation and bacterial growth by peptide nucleic acid targeted to ribosomal RNA. Proc. Natl. Acad. Sci. U. S. A. 95:1998;2073-2076.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 2073-2076
    • Good, L.1    Nielsen, P.E.2
  • 61
    • 0032548490 scopus 로고    scopus 로고
    • Polyamide nucleic acid targeted to the primer binding site of the HIV-1 RNA genome blocks in vitro HIV-1 reverse transcription
    • Lee R., et al. Polyamide nucleic acid targeted to the primer binding site of the HIV-1 RNA genome blocks in vitro HIV-1 reverse transcription. Biochemistry. 37:1998;900-910.
    • (1998) Biochemistry , vol.37 , pp. 900-910
    • Lee, R.1
  • 62
    • 0032403229 scopus 로고    scopus 로고
    • Modified (PNA, 2′-O-methyl and phosphoramidate) anti-TAR antisense oligonucleotides as strong and specific inhibitors of in vitro HIV-1 reverse transcription
    • Boulmé F., et al. Modified (PNA, 2′-O-methyl and phosphoramidate) anti-TAR antisense oligonucleotides as strong and specific inhibitors of in vitro HIV-1 reverse transcription. Nucleic Acids Res. 26:1998;5492-5500.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 5492-5500
    • Boulmé, F.1
  • 63
    • 0028129843 scopus 로고
    • Stability of peptide nucleic acids in human serum and cellular extracts
    • Demidov V.V., et al. Stability of peptide nucleic acids in human serum and cellular extracts. Biochem. Pharmacol. 48:1994;1310-1313.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1310-1313
    • Demidov, V.V.1
  • 64
    • 0032518178 scopus 로고    scopus 로고
    • Synthesis and evaluation of some properties of chimeric oligomers containing PNA and phosphono-PNA residues
    • Efimov V.A., et al. Synthesis and evaluation of some properties of chimeric oligomers containing PNA and phosphono-PNA residues. Nucleic Acids Res. 26:1998;566-575.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 566-575
    • Efimov, V.A.1
  • 65
    • 0036363313 scopus 로고    scopus 로고
    • In vitro and in vivo studies on pharmacokinetics and metabolism of PNA constructs in rodents
    • P.E. Nielsen. Humana Press
    • Kristensen E. In vitro and in vivo studies on pharmacokinetics and metabolism of PNA constructs in rodents. Nielsen P.E. Peptide Nucleic Acids: Methods and Protocols. 2002;259-269 Humana Press.
    • (2002) Peptide Nucleic Acids: Methods and Protocols , pp. 259-269
    • Kristensen, E.1
  • 66
    • 0032560835 scopus 로고    scopus 로고
    • Stability and structural features of the duplexes containing nucleoside analogs with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides
    • Obika S., et al. Stability and structural features of the duplexes containing nucleoside analogs with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides. Tetrahedron Lett. 39:1998;5401-5404.
    • (1998) Tetrahedron Lett. , vol.39 , pp. 5401-5404
    • Obika, S.1
  • 67
    • 0343065617 scopus 로고    scopus 로고
    • LNA (locked nucleic acids): Synthesis and high-affinity nucleic acid recognition
    • Singh S.K., et al. LNA (locked nucleic acids): synthesis and high-affinity nucleic acid recognition. Chem. Commun. 1:1998;455-456.
    • (1998) Chem. Commun. , vol.1 , pp. 455-456
    • Singh, S.K.1
  • 68
    • 0000752107 scopus 로고    scopus 로고
    • Universality of LNA-mediated high-affinity nucleic acid recognition
    • Singh S.K., Wengel J. Universality of LNA-mediated high-affinity nucleic acid recognition. Chem. Commun. 1:1998;1247-1248.
    • (1998) Chem. Commun. , vol.1 , pp. 1247-1248
    • Singh, S.K.1    Wengel, J.2
  • 69
    • 0035113736 scopus 로고    scopus 로고
    • Locked nucleic acid (LNA): Fine-tuning the recognition of DNA and RNA
    • Braasch D.A., Corey D.R. Locked nucleic acid (LNA): fine-tuning the recognition of DNA and RNA. Chem. Biol. 8:2001;1-7.
    • (2001) Chem. Biol. , vol.8 , pp. 1-7
    • Braasch, D.A.1    Corey, D.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.