VEGF localisation in diabetic retinopathy

British Journal of Ophthalmology

Volumn 82, Issue 5, 1998, Pages 561-568

  Boulton, Mike ^a   Foreman, David ^a   Williams, Gillian ^a   McLeod, David ^a  

^a MANCHESTER ROYAL EYE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; VASCULOTROPIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LASER COAGULATION; PRIORITY JOURNAL; PROLIFERATIVE RETINOPATHY; PROTEIN LOCALIZATION; RETINA VASCULITIS; VASCULAR ENDOTHELIUM;

EID: 0031781305     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.82.5.561     Document Type: Article

References (36)

1. Garner A. Vascular diseases. In: Garner A, Klintworth GK, eds. Pathobiology of ocular disease. A dynamic approach. 2nd ed. New York: Marcel Dekker, 1994:1625-710.
2. Michaelson IC. The mode of development of the vascular system of the retina with some observations on its significance for certain retinal disorders. Trans Ophthalmol Soc UK 1948;68:137-80.
3. Hanneken A, de Juan E, Lutty GA, et al. Altered distribution of basic fibroblast growth factor in diabetic retinopathy. Arch Ophthalmol 1991;109:1005-11.
4. Robbins SG, Mixon RN, Wilson DJ, et al. Platelet-derived growth factor ligands and receptors immunolocalized in proliferative retinal disorders. Invest Ophthalmol Vis Sci 1994;35:3649-63.
5. Dills DG, Moss SE, Klein R, et al. Association of elevated IGF-1 levels with increased retinopathy in late-onset diabetes. Diabetes 1991;40:1725-30.
6. Minchenko A, Bauer T, Salceda S, et al. Hypoxic stimulation of vascular endothelial growth factor expression in vivo and in vitro. Lab Invest 1994;71:374-9.
7. deVries C, Escobedo JA, Ueno H, et al. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 1992;255:989-91.
8. Terman BI, Vermazen MD, Carrion ME, et al. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial growth factor. Biochem Biophys Res Commun 1992;34:1578-86.
9. Quinn T, Peter KG, deVries C, et al. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci USA 1993;90:7533-7.
10. Guerrin M, Moukadiri H, Chollet P, et al. Vasculotropin/ vascular endothelial growth factor is an autocrine growth factor for human retinal pigment epithelial cells cultured in vitro. J Cell Physiol 1995;164:385-94.
11. Thieme H, Aiello LP, Takagi H, et al. Comparative analysis of vascular endothelial growth factor receptors on retinal and aortic vascular endothelial cells. Diabetes 1995;44:98-103.
12. Tuder RM, Flook BE, Voelkel NF. Increased gene expression for VEGF and the VEGF receptor KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. J Clin Invest 1995;95;1798-807.
13. Miller JW, Adamis AP, Shima DT, et al. Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angogenesis in a primate model. Am J Path 1994;145:574-84.
14. Pe'er J, Shweiki D, Itin A, Hemo I, et al. Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularising ocular diseases. Lab Invest 1995;72:638-45.
15. Pe'er J, Folberg R, Itin A, et al. Upregulated expression of vascular endothelial growth factor in proliferative diabetic retinopathy. Br J Ophthalmol 1996;80:241-5.
16. Stone J, Pe'er J, Chan-Ling T, et al. The roles of vascular endothelial growth factor and neuroglia in the pathogensis of retinopathy of prematurity. Invest Ophthalmol Vis Sci 1995;36(suppl):871.
17. Pierce E, Foley ED, Smith LEH. Regulation of retinal vascular endothelial growth factor (VEGF/VPF) levels by hyperoxia and hypoxia: a possible etiology for ROP. Invest Ophthalmol Vis Sci 1995;36(suppl):871.
18. Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 1994;331: 1480-7.
19. Adamis AP, Miller JW, Bernal M-T, et al. Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am J Ophthalmol 1994; 118:445-50.
20. Malecaze F, Clamens S, Simorre-Pinatel V, et al. Detection of vascular endothelial growth factor messenger RNA and vascular endothelial growth factor-like activity in proliferative diabetic retinopathy. Arch Ophthalmol 1994;112:1476-82.
21. Lutty GA, McLeod DS, Merges C, et al. Localization of vascular endothelial growth factor in human retina and choroid. Arch Ophthalmol 1996;114:971-7.
22. Murata T, Isibashi T, Khalil M, et al. Vascular endothelial growth factor plays a role in hyperpermeability of diabetic retinal vessels. Ophthalmic Res 1995;27:48-52.
23. Robbins SG, Penn JS, Conaway JR, et al. Distribution of vascular endothelial growth factor (VEGF) in normal and oxygen-injured rat retinas. Invest Ophthalmol Vis Sci 1995;36(suppl):871.
24. Youssri AI, Luma J, Vinores S, et al. Immunohistochemical localisation of vascular endothelial growth factor (VEGF) in retinas with oxygen-induced ischemic retinopathy and non-ischemic retinas. Invest Ophthalmol Vis Sci 1995; 36(suppl):401.
25. Amin R, Frank R, Kennedy A, et al. Vascular endothelial growth factor is present in glial cells of the retina and optic nerve of human subjects with non-proliferative diabetic retinopathy. Invest Ophthalmol Vis Sci 1997;38:36-47.
26. Houck KA, Ferrara N, Winer J, et al. The vascular endothelial growth factor family: four molecular species and characterisation of alternative splicing of RNA. Mol Endocrinol 1991;5:1806-14.
27. Senger DR, Van De Walter L, Brown LF, et al. Vascular permeability factor (VPF, VEGF) in tumor biology. Cancer Metastasis Rev 1993;12:303-24.
28. Connolly DT, Olander JV, Heuvelman D, et al. Human vascular permeability factor. J Biol Chem 1989;264:20017-24.
29. Murata T, Nakagawa K, Khalil A, et al. The relation between expression of vascular endothelial growth factor and breakdown of the blood retinal barrier in diabetic rat retinas. Lab Invest 1996;74:819-25.
30. Dvorak HF. Tumors: wounds that do not heal. Similarity between stroma generation and wound healing. N Engl J Med 1986;315:1650-6.
31. Ferrara N, Henzel WJ. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 1989;161:851-9.
32. Leung DW, Cachianes G, Kuang W-J, et al. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989;246:1306-9.
33. Tolentino M, Miller J, Gragoudas E, et al. Intravitreous injections of vascular endothelial growth factor produce retinal ischaemia and microangiopathy in an adult primate. Ophthalmology 1996;103:1820-8.
34. Chen Y-S, Hackett S, Schoenfeld C-L, et al. Localisation of vascular endothelial growth factor and its receptors to cells of vacular and avascular epiretinal membranes. Br J Ophthalmol 1997;81:919-26.
35. Boulton ME, Foreman D, McLeod D. Vascularised vitreoretinopathy: the role of growth factors. Eye 1996;10: 691-6.
36. Khaliq A, Foreman D, Ahmed A, et al. Increased expression of placenta growth factor (PIGF) in proliferative diabetic retinopathy. Lab Invest 1998; (in press).