Gastrin-Releasing Peptide Is a Novel Mediator of Proximal Nutrient-Induced Proglucagon-Derived Peptide Secretion from the Distal Gut

Endocrinology

Volumn 137, Issue 6, 1996, Pages 2383-2388

  Roberge, J N ^a   Gronau, K A ^a   Brubaker, P L ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIN RELEASING PEPTIDE; NEUROPEPTIDE; PROGLUCAGON;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DUODENUM SECRETION; FAT INTAKE; HORMONAL REGULATION; HORMONE SYNTHESIS; INSULIN RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT;

ANIMALS; CORN OIL; DIETARY FATS; DUODENUM; GASTRIN-RELEASING PEPTIDE; GASTRINS; GLUCAGON; GLUCAGON-LIKE PEPTIDES; INTESTINES; KINETICS; MALE; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PEPTIDES; PROGLUCAGON; PROTEIN PRECURSORS; RATS; RATS, WISTAR;

EID: 0029931341     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.6.8641190     Document Type: Article

References (45)

1. Mojsov S, Heinrich G, Wilson IB, Ravazzola M, Orci L, Habener JF 1986 Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing. J Biol Chem 261:11880-11889
2. Mojsov S, Kopczynski MG, Habener JF 1990 Both amidated and nonamidated forms of glucagon-like peptide I are synthesized in the rat intestine and the pancreas. J Biol Chem 265:8001-8008
3. Brubaker PL, So DCY, Drucker DJ 1989 Tissue-specific differences in the levels of proglucagon-derived peptides in streptozotocin-induced diabetes. Endocrinology 124:3003-3009
4. Orskov C, Rabenhoj L, Wettergren A, Kofod H, Holst JJ 1994 Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans. Diabetes 43:535-539
5. Tucker JD, Dhanvantari S, Brubaker PL, Processing of proglucagon in islet and intestinal cell lines. Regul Pept, in press.
6. Bataille D, Tatemoto K, Gespach C, Jornvall H, Rosselin G, Mutt V 1982 Isolation of glucagon-37 (bioactive enteroglucagon/oxyntomodulin) from porcine jejuno-ileum: characterization of the peptide. FEBS Lett 146:79-86
7. Schjoldager BTG, Mortensen PE, Christiansen J, Orskov C, Holst JJ 1989 GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans. Dig Dis Sci 34:703-708
8. Göke R, Fehmann H-C, Göke B 1991 Glucagon-like peptide-1(7-36) amide is a new incretin/enterogastrone candidate. Eur J Clin Invest 21:135-144
9. (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas. J Clin Invest 79:616-619
10. Gutniak M, Orskov C, Holst JJ, Ahrén B, Efendic S 1992 Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus. N Engl J Med 326: 1316-1322
11. Kreymann B, Ghatei MA, Williams G, Bloom SR 1987 Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet 2:1300-1304
12. Nathan DM, Schreiber E, Fogel H, Mojsov S, Habener JF 1992 Insulinotropic action of glucagonlike peptide-I-(7-37) in diabetic and nondiabetic subjects. Diabetes Care 15:270-276
13. Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeldt W 1993 Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 36:741-744
14. Rocca AS, Brubaker PL 1995 Stereospecific effects of fatty acids on proglucagon-derived peptide secretion in fetal rat intestinal cultures. Endocrinology 136:5593-5599
15. Larsson L-I, Holst J, Hakanson R, Sundler F 1975 Distribution and properties of glucagon immunoreactivity in the digestive tract of various mammals: an immunohistochemical and immunochemical study. Histochemistry 44:281-290
16. Eissele R, Göke R, Willemer S, Harthus H-P, Vermeer H, Arnold R, Göke B 1992 Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. Eur J Clin Invest 22:283-291
17. Roberge JN, Brubaker PL 1991 Secretion of proglucagon-derived peptides in response to intestinal luminal nutrients. Endocrinology 128:3169-3174
18. Roberge JN, Brubaker PL 1993 Regulation of intestinal proglucagon-derived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop. Endocrinology 133:233-240
19. Elliott RM, Morgan LM, Tredger JA, Deacon S, Wright J, Marks V 1993 Glucagon-like peptide-1(7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns. J Endocrinol 138:159-166
20. Brubaker PL 1991 Regulation of intestinal proglucagon-derived peptide secretion by intestinal regulatory peptides. Endocrinology 128:3175-3182
21. Huang THJ, Brubaker PL 1995 Synthesis and secretion of glucagon-like peptide-1 by fetal rat intestinal cells in culture. Endocrine 3:499-503
22. Hermann-Rinke C, Vöge A, Hess M, Göke B 1995 Regulation of glucagon-like peptide-1 secretion from rat ileum by neurotransmitters and peptides. J Endocrinol 147:25-31
23. Dumoulin V, Dakka T, Plaisancie P, Chayvialle J-A, Cuber J-C 1995 Regulation of glucagon-like peptide-1-(7-36)amide, peptide YY, and neurotensin secretion by neurotransmitters and gut hormones in the isolated vascularly perfused rat ileum. Endocrinology 136:5182-5188
24. Nauck MA, Bartels E, Orskov C, Ebert R, Creutzfeldt W 1993 Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations. J Clin Endocrinol Metab 76:912-917
25. McDonald TJ, Ghatei MA, Bloom SR, Track NS, Radziuk J, Dupre J, Mutt V 1981 A qualitative comparison of canine plasma gastroenteropancreatic hormone responses to bombesin and the porcine gastrin-releasing peptide (GRP). Regul Pept 2:293-304
26. McDonald TJ, Ghatei MA, Bloom SR, Adrian TE, Mochizuki T, Yanaihara C, Yanaihara N 1983 Dose-response comparisons of canine plasma gastroenteropancreatic hormone responses to bombesin and the porcine gastrin-releasing peptide (GRP). Regul Pept 5:125-137
27. Greenberg GR, Chan B, McDonald TJ, Alleyne J 1985 The role of vagal integrity in gastrin releasing peptide stimulated gastroenteropancreatic hormone release and gastric acid secretion. Regul Pept 10:179-187
28. Singh P, Guo Y-S, Kull FC, Leban JJ 1992 A novel bombesin receptor antagonist (2258U89), potently inhibits bombesin evoked release of gastrointestinal hormones from rats and dogs, in vitro and in vivo. Regul Pept 40:75-86
29. Greenberg GR 1987 Influence of vagal integrity on gastrin and somatostatin release in dogs. Gastroenterology 93:994-1001
30. Tanaka R, Matsuyama T, Shima K, Sawazaki N, Tarui S, Kumahara Y 1979 Half life of gastrointestinal glucagon-like immunoreactive materials. Endocrinol Jpn 26:59-63
31. Kervran A, Dubrasquet M, Blache P, Martinez J, Bataille D 1990 Metabolic clearance rates of oxyntomodulin and glucagon in the rat: contribution of the kidney. Regul Pept 31:41-52
32. Knuhtsen S, Holst JJ, Knigge U, Olesen M, Nielsen OV 1984 Radioimmunoassay, pharmacokinetics, and neuronal release of gastrin-releasing peptide in anesthetized pigs. Gastroenterology 87:372-378
33. Larsson LT, Moody AJ 1980 Glicentin and gastric inhibitory polypeptide immunoreactivity in endocrine cells of the gut and pancreas. J Histochem Cytochem 28:925-933
34. Ferri G-L, Adrian TE, Ghatei MA, O'Shaughnessy DJ, Probert L, Lee YC, Buchan AMJ, Polak JM, Bloom SR 1983 Tissue localization and relative distribution of regulatory peptides in separated layers from the human bowei. Gastroenterology 84:777-786
35. Moghimzadeh E, Ekman R, Hakanson R, Yanaihara N, Sundler F 1983 Neuronal gastrin-releasing peptide in the mammalian gut and pancreas. Neuroscience 10:553-563
36. Dockray GJ, Vaillant C, Walsh JH 1979 The neuronal origin of bombesin-like immunoreactivity in the rat gastrointestinal tract Neuroscience 4:1561-1568
37. Williams JA, Korc M, Dormer RL 1978 Action of secretagogues on a new preparation of functionally intact, isolated pancreatic acini. Am J Physiol (Endocrinol Metab) 235:E517-E524
38. Li Y, Owyang C 1993 Vagal afferent pathway mediates physiological action of cholecystokinin on pancreatic enzyme secretion. J Clin Invest 92:418-424
39. Kieffer TJ, Buchan AMJ, Barker H, Brown JC, Pederson RA 1994 Release of gastric inhibitory polypeptide from cultured canine endocrine cells. Am J Physiol (Endocrinol Metab) 267:E489-E496
40. Greeley Jr GH, Spannagel A, Trowbridge J, Thompson JC 1986 Effect of bombesin and gastrin-releasing peptide on the release of gastric inhibitory polypeptide and insulin in rats. Proc Soc Exp Biol Med 182:540-542
41. Kohn DF, Barthold SW 1984 Biology, diseases of rats. In: Fox JG, Cohen BJ, Loew FM (eds) Laboratory Animal Medicine. Academic Press, Orlando, pp 91-122
42. Ewert WR, Wingate DL 1984 Central representation of arrival of nutrient in the duodenum. Am J Physiol (Gastrointest Liver Physiol) 246:G750-G756
43. Melone J 1986 Vagal receptors sensitive to lipids in the small intestine of the cat. J Auton Nerv Syst 17:231-241
44. Kirschgessner AL, Gershon MD 1989 Identification of vagal efferent fibers and putative target neurons in the enteric nervous system of the rat. J Comp Neurol 285:38-53
45. Berthoud H-R, Jedrzejewska A, Powley TL 1990 Simultaneous labeling of vagal innervation of the gut and afferent projections from the visceral forebrain with Dil injected into the dorsal vagal complex in the rat. J Comp Neurol 301:65-79