GLP-2 augments the adaptive response to massive intestinal resection in rat

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 275, Issue 5 38-5, 1998, Pages

  Scott, R B ^a,b   Kirk, D ^b   Macnaughton, W K ^b   Meddings, J B ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Glucagon like peptide 2; Growth factor; Intestinal adaptation; Short gut

Indexed keywords

GLUCAGON LIKE PEPTIDE; GLUCAGON LIKE PEPTIDE 2; GLUCAGON LIKE PEPTIDE 2 DERIVATIVE; SUCRASE; TEDUGLUTIDE; UNCLASSIFIED DRUG; XYLOSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FOOD INTAKE; ILEUM; INTESTINE ABSORPTION; INTESTINE ADAPTATION; INTESTINE CRYPT; INTESTINE RESECTION; JEJUNUM; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; WEIGHT GAIN;

EID: 0031735064     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1998.275.5.g911     Document Type: Article

References (19)

1. Bloom, S. R., and J. M. Polak. The hormonal pattern of intestinal adaptation: a major role for enteroglucagon. Scand. J. Gastroenterol. 17: 93-103, 1982.
2. Bristol, J. B., and R. C. N. Williamson. Post-operative adaptation of the small intestine. World J. Surg. 9: 825-832, 1985.
3. Brubaker, P. L., A. Izzo, M. Hill, and D. J. Drucker. Intestinal function in mice with small bowel growth induced by glucagon-like peptide-2. Am. J. Physiol. 272 (Endocrinol. Metab. 35): E1050-E1058, 1997.
4. Byrne, T. A., T. Morrissey, T. Naltakom, T. Ziegler, and D. Wilmore. Growth hormone, glutamine and modified diet enhance nutrient absorption in patients with severe short bowel syndrome. JPEN J. Parenter. Enteral Nutr. 19: 296-302, 1995.
5. Byrne, T. A., R. C. Persinger, L. S. Young, T. Ziegler, and D. Wilmore. A new treatment for patients with short bowel syndrome. Ann. Surg. 222: 243-255, 1995.
6. Cheeseman, C. I., and R. Tsang. The effect of GIP and glucagon-like peptides on intestinal basolateral membrane hexose transport. Am. J. Physiol. 271 (Gastrointest. Liver Physiol. 34): G477-G482, 1996.
7. Dahlqvist, A. Method for assay of intestinal disaccharidases. Anal. Biochem. 7: 18-25, 1964.
8. Dowling, R. H. Small bowel adaptation, and its regulation. Scand. J. Gastroenterol. 17: 53-74, 1982.
9. Dowling, R. H., and C. C. Booth. Structural and functional changes following small intestinal resection in the rat. Clin. Sci. (Colch.) 32: 139-149, 1967.
10. Drucker, D. J. Epithelial cell growth and differentiation. I. Intestinal growth factors. Am. J. Physiol. 273 (Gastrointest. Liver Physiol. 36): G3-G6, 1997.
11. 2]glucagon-like peptide 2. Am. J. Physiol. 273 (Gastrointest. Liver Physiol. 36): G1252-G1262, 1997.
12. Drucker, D. J., P. Erlich, S. L. Asa, and P. L Brubaker. Induction of intestinal epithelial proliferation by glucagon-like peptide 2. Proc. Natl. Acad. Sci. USA 93: 7911-7916, 1996.
13. Drucker, D. J., Q. Shi, A. Crivici, M. Sumner-Smith, W. Tavares, M. Hill, L. DeForest, S. Cooper, and P. L. Brubaker. Regulation of the biological activity of glucagon-like peptide-2 in vivo by dipeptidyl peptidase IV. Nat. Biotechnol. 15: 673-677, 1997.
14. Finlay, J. M., J. Hogarth, and K. J. R. Wightman. A clinical evaluation of the D-xylose tolerance test. Ann. Intern. Med. 61: 411-422, 1964.
15. Flint, J. M. The effect of extensive resection of the small intestine. Bull. Johns Hopkins Hosp. 23: 127-144, 1921.
16. Gleeson, M. H., S. R. Bloom, J. M. Polak, K. Henry, and R. J. Dowling. Endocrine tumor in kidney affecting small bowel structure, motility and absorptive function. Gut 12: 773-782, 1971.
17. Hanson, W. R. Compensation by the residual intestine after intestinal resection in the rat. II. Influence of postoperative time interval. Gastroenterology 73: 701-705, 1977.
18. Hanson, W. R., J. W. Osborne, and J. G. Sharpe. Compensation by the residual intestine after intestinal resection in the rat. I. Influence of amount of tissue removed. Gastroenterology 73: 692-700, 1977.
19. Hines, O. J., A. J. Bilchik, M. J. Zinner, M. J. Skotzko, J. A. Moser, D. W. McFadden, and S. W. Ashley. Adaptation of the Na/glucose cotransporter following intestinal resection. J. Surg. Res. 57: 22-27, 1994.