Disease Progression Despite Early Loss of Polyglutamine Protein Expression in SCA7 Mouse Model

Journal of Neuroscience

Volumn 24, Issue 8, 2004, Pages 1881-1887

  Helmlinger, Dominique ^a   Abou Sleymane, Gretta ^a   Yvert, Gaël ^a,c   Rousseau, Stéphane ^b   Weber, Chantal ^a   Trottier, Yvon ^a   Mandel, Jean Louis ^a   Devys, Didier ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSTITUT CLINIQUE DE LA SOURIS   (France)

^c CNRS   (France)

Author keywords

Aggregates; Neurodegeneration; Polyglutamine; Retina; Reversibility; Transcriptional alteration

Indexed keywords

ATAXIN 7; DNA; POLYGLUTAMINE; PROTEIN; RHODOPSIN; RNA; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DISEASE COURSE; DOWN REGULATION; ELECTRORETINOGRAPHY; GENE EXPRESSION; HUNTINGTON CHOREA; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOLOGY; MICROSCOPY; MOUSE; NERVE DEGENERATION; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PHOTORECEPTOR; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA DISEASE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINOCEREBELLAR DEGENERATION; TRANSGENE;

AGE FACTORS; ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DOWN-REGULATION; ELECTRORETINOGRAPHY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUNTINGTON DISEASE; MACROMOLECULAR SUBSTANCES; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDES; PHOTORECEPTORS, VERTEBRATE; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; RETINAL DEGENERATION; RHODOPSIN; SPINOCEREBELLAR ATAXIAS; TRANSGENES; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 1442324773     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4407-03.2004     Document Type: Article

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