-
1
-
-
2942589064
-
Evolutionary and functional relationships within the DJ1 superfamily
-
Bandyopadhyay S, Cookson MR (2004) Evolutionary and functional relationships within the DJ1 superfamily. BMC Evol Biol 4: 6.
-
(2004)
BMC Evol Biol
, vol.4
, pp. 6
-
-
Bandyopadhyay, S.1
Cookson, M.R.2
-
2
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, et al. (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299: 256-259.
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
-
3
-
-
2942684871
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
Canet-Aviles RM, Wilson MA, Miller DW, Ahmad R, McLendon C, et al. (2004) The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc Natl Acad Sci U S A 101: 9103-9108.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
-
4
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy
-
Conway KA, Lee SJ, Rochet JC, Ding TT, Williamson RE, et al. (2000) Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy. Proc Natl Acad Sci U S A 97: 571-576.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.J.2
Rochet, J.C.3
Ding, T.T.4
Williamson, R.E.5
-
5
-
-
4344659685
-
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
-
Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D (2004) Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 305: 1292-1295.
-
(2004)
Science
, vol.305
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stefanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
6
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
Dauer W, Przedborski S (2003) Parkinson's disease: Mechanisms and models. Neuron 39: 889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
7
-
-
0042521076
-
The environment and Parkinson's disease: Is the nigrostriatal system preferentially targeted by neurotoxins?
-
Di Monte DA (2003) The environment and Parkinson's disease: Is the nigrostriatal system preferentially targeted by neurotoxins? Lancet Neurol 2: 531-538.
-
(2003)
Lancet Neurol
, vol.2
, pp. 531-538
-
-
Di Monte, D.A.1
-
8
-
-
0142059791
-
Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1
-
Dong Z, Ferger B, Paterna JC, Vogel D, Furler S, et al. (2003) Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1. Proc Natl Acad Sci U S A 100: 12438-12443.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12438-12443
-
-
Dong, Z.1
Ferger, B.2
Paterna, J.C.3
Vogel, D.4
Furler, S.5
-
9
-
-
2442636348
-
Biomedicine. Parkinson's - Divergent causes, convergent mechanisms
-
Greenamyre JT, Hastings TG (2004) Biomedicine. Parkinson's - Divergent causes, convergent mechanisms. Science 304: 1120-1122.
-
(2004)
Science
, vol.304
, pp. 1120-1122
-
-
Greenamyre, J.T.1
Hastings, T.G.2
-
10
-
-
4444231730
-
How many pathways are there to nigral death?
-
Hardy J, Langston JW (2004) How many pathways are there to nigral death? Ann Neurol 56: 316-318.
-
(2004)
Ann Neurol
, vol.56
, pp. 316-318
-
-
Hardy, J.1
Langston, J.W.2
-
11
-
-
13944279784
-
Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: An ES-derived cell model of primary parkinsonism
-
Martinat C, Shendelman SB, Jonason A, Leete T, Beal MF, et al. (2004) Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: An ES-derived cell model of primary parkinsonism. PLoS Biol 2: e327.
-
(2004)
PLoS Biol
, vol.2
-
-
Martinat, C.1
Shendelman, S.B.2
Jonason, A.3
Leete, T.4
Beal, M.F.5
-
13
-
-
1542349213
-
Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function
-
Olzmann JA, Brown K, Wilkinson KD, Rees HD, Huai Q, et al. (2004) Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function. J Biol Chem 279: 8506-8515.
-
(2004)
J Biol Chem
, vol.279
, pp. 8506-8515
-
-
Olzmann, J.A.1
Brown, K.2
Wilkinson, K.D.3
Rees, H.D.4
Huai, Q.5
-
14
-
-
0037137702
-
Parkin protects against the toxicity associated with mutant alpha-synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons
-
Petrucelli L, O'Farrell C, Lockhart PJ, Baptista M, Kehoe K, et al. (2002) Parkin protects against the toxicity associated with mutant alpha-synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons. Neuron 36: 1007-1019.
-
(2002)
Neuron
, vol.36
, pp. 1007-1019
-
-
Petrucelli, L.1
O'Farrell, C.2
Lockhart, P.J.3
Baptista, M.4
Kehoe, K.5
-
15
-
-
4043079949
-
Mitochondria and dopamine: New insights into recessive parkinsonism
-
Shen J, Cookson MR (2004) Mitochondria and dopamine: New insights into recessive parkinsonism. Neuron 43: 301-304.
-
(2004)
Neuron
, vol.43
, pp. 301-304
-
-
Shen, J.1
Cookson, M.R.2
-
16
-
-
13944267769
-
DJ-1 is a redox-dependent molecular chaperone that inhibits α-synuclein aggregation formation
-
Shendelman S, Jonason A, Martinat C, Leete T, Abeliovich A (2004) DJ-1 is a redox-dependent molecular chaperone that inhibits α-synuclein aggregation formation. PLoS Biol 2: e362.
-
(2004)
PLoS Biol
, vol.2
-
-
Shendelman, S.1
Jonason, A.2
Martinat, C.3
Leete, T.4
Abeliovich, A.5
-
17
-
-
0035854437
-
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, et al. (2001) Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease. Science 293: 263-269.
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
-
18
-
-
0242300619
-
Alpha-synuclein locus triplication causes Parkinson's disease
-
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, et al. (2003) Alpha-synuclein locus triplication causes Parkinson's disease. Science 302: 841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
-
19
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, et al. (2004) Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304: 1158-1160.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
-
20
-
-
0038386274
-
Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease
-
Volles MJ, Lansbury PT (2003) Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease. Biochemistry 42: 7871-7878.
-
(2003)
Biochemistry
, vol.42
, pp. 7871-7878
-
-
Volles, M.J.1
Lansbury, P.T.2
-
21
-
-
0037468831
-
Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
-
Yang Y, Nishimura I, Imai Y, Takahashi R, Lu B (2003) Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron 37: 911-924.
-
(2003)
Neuron
, vol.37
, pp. 911-924
-
-
Yang, Y.1
Nishimura, I.2
Imai, Y.3
Takahashi, R.4
Lu, B.5
-
22
-
-
0345357664
-
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition
-
Yokota T, Sugawara K, Ito K, Takahashi R, Ariga H, et al. (2003) Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition. Biochem Biophys Res Commun 312: 1342-1348.
-
(2003)
Biochem Biophys Res Commun
, vol.312
, pp. 1342-1348
-
-
Yokota, T.1
Sugawara, K.2
Ito, K.3
Takahashi, R.4
Ariga, H.5
-
23
-
-
0034700158
-
Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
-
Zhang Y, Gao J, Chung KK, Huang H, Dawson VL, et al. (2000) Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc Natl Acad Sci U S A 97: 13354-13359.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13354-13359
-
-
Zhang, Y.1
Gao, J.2
Chung, K.K.3
Huang, H.4
Dawson, V.L.5
|