S-adenosylhomocysteine hydrolase from the archaeon Pyrococcus furiosus: Biochemical characterization and analysis of protein structure by comparative molecular modeling

Proteins: Structure, Function and Genetics

Volumn 58, Issue 4, 2005, Pages 815-825

  Porcelli, Marina ^a   Moretti, Maria Angela ^a   Concilio, Luigi ^a   Forte, Sabrina ^a   Merlino, Antonello ^a   Graziano, Giuseppe ^b   Cacciapuoti, Giovanna ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b UNIVERSITY OF SANNIO   (Italy)

Author keywords

Adenosylhomocysteine metabolism; Disulfide bonds; Homology modeling; Hyperthermophilic enzymes; NAD binding domain; Protein stability; S adenosylhomocysteine hydrolase

Indexed keywords

ADENOSINE; ADENOSYLHOMOCYSTEINASE; CYSTEINE; DITHIOTHREITOL; HOMOCYSTEINE; LYSINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; S ADENOSYLHOMOCYSTEINE; TETRAMER; THIOL GROUP; THREONINE; TYROSINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARCHAEBACTERIUM; ARTICLE; CARBOXY TERMINAL SEQUENCE; CLONE; DISULFIDE BOND; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STABILITY; ENZYME SUBUNIT; ESCHERICHIA COLI; GENETIC CONSERVATION; HIGH TEMPERATURE; HYDROPHOBICITY; MELTING POINT; METHYLATION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PYROCOCCUS FURIOSUS; TEMPERATURE ACCLIMATIZATION; THERMOSTABILITY;

ADENOSINE; ADENOSYLHOMOCYSTEINASE; AMINO ACID SEQUENCE; CATALYSIS; CLONING, MOLECULAR; CYSTEINE; DISULFIDES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEAT; HOMOCYSTEINE; KINETICS; LYSINE; METHYLATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLASMIDS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PYROCOCCUS; PYROCOCCUS FURIOSUS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SULFOLOBUS SOLFATARICUS; TEMPERATURE; THREONINE;

EID: 13944254408     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.20381     Document Type: Article

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