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Volumn 277, Issue 9, 2002, Pages 7477-7482
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Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase coplexed with D-eritadenine
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Author keywords
[No Author keywords available]
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Indexed keywords
CONFORMATIONS;
ENZYME INHIBITION;
ENZYMES;
HYDROGEN BONDS;
MOLECULAR STRUCTURE;
SUGARS;
INHIBITOR BINDING;
BIOCHEMISTRY;
ADENOSINE;
ADENOSINE DERIVATIVE;
ADENOSYLHOMOCYSTEINASE;
ERITADENINE;
HISTIDINE;
NICOTINAMIDE ADENINE DINUCLEOTIDE;
S ADENOSYLHOMOCYSTEINE HYDROLASE INHIBITOR;
SUGAR ACID;
UNCLASSIFIED DRUG;
ARTICLE;
CHEMICAL BINDING;
CHEMICAL STRUCTURE;
CHIRALITY;
COMPLEX FORMATION;
CONFORMATIONAL TRANSITION;
CRYSTAL STRUCTURE;
DRUG DESIGN;
DRUG MECHANISM;
DRUG STRUCTURE;
ENZYME ACTIVE SITE;
ENZYME BINDING;
ENZYME CONFORMATION;
ENZYME INHIBITION;
ENZYME INHIBITOR INTERACTION;
HYDROGEN BOND;
IC 50;
INHIBITION KINETICS;
MOLECULAR MODEL;
OXIDATION;
PRIORITY JOURNAL;
ULTRAVIOLET RADIATION;
ADENINE;
ADENOSINE;
ADENOSYLHOMOCYSTEINASE;
ANIMALS;
ANTICHOLESTEREMIC AGENTS;
BINDING SITES;
CRYSTALLOGRAPHY, X-RAY;
ESCHERICHIA COLI;
HYDROLASES;
MODELS, CHEMICAL;
MODELS, MOLECULAR;
PLASMIDS;
PROTEIN BINDING;
RATS;
ULTRAVIOLET RAYS;
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EID: 0036510742
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.M109187200 Document Type: Article |
Times cited : (45)
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References (40)
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