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Volumn 6, Issue 5, 2000, Pages 505-506

Converting hepatocytes to β-cells - A new approach for diabetes?

Author keywords

[No Author keywords available]

Indexed keywords

FURIN; GLUCOSE TRANSPORTER; HOMEODOMAIN PROTEIN; INSULIN; PROINSULIN;

EID: 0034071364     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/74980     Document Type: Short Survey
Times cited : (18)

References (10)
  • 1
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    • PDX-1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
    • Ferber, S. et al. PDX-1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nature Med. 6, 568-572. (2000).
    • (2000) Nature Med. , vol.6 , pp. 568-572
    • Ferber, S.1
  • 2
    • 0033979603 scopus 로고    scopus 로고
    • Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice
    • Soria, B. et al. Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 49, 157-161 (2000).
    • (2000) Diabetes , vol.49 , pp. 157-161
    • Soria, B.1
  • 4
    • 0030751585 scopus 로고    scopus 로고
    • Glucose-stimulated genes and prospects of gene therapy for type 1 diabetes
    • Mitanchez, D., Doiron, B., Chen, R. & Kahn, A. Glucose-stimulated genes and prospects of gene therapy for type 1 diabetes. Endocrine Rev. 1B, 520-540 (1997).
    • (1997) Endocrine Rev. , vol.1 B , pp. 520-540
    • Mitanchez, D.1    Doiron, B.2    Chen, R.3    Kahn, A.4
  • 5
    • 0032536095 scopus 로고    scopus 로고
    • Regulated expression of mature human insulin in the liver of transgenic mice
    • Mitanchez, D. et al. Regulated expression of mature human insulin in the liver of transgenic mice. FEBS. Lett. 421, 285-289 (1998).
    • (1998) FEBS. Lett. , vol.421 , pp. 285-289
    • Mitanchez, D.1
  • 6
    • 0034004456 scopus 로고    scopus 로고
    • Glucose regulated production of human insulin in rat hepatocytes
    • Thulé, P.M., Liu, J & Phillips, L.S. Glucose regulated production of human insulin in rat hepatocytes. Gene Ther. 7, 205-214 (2000).
    • (2000) Gene Ther. , vol.7 , pp. 205-214
    • Thulé, P.M.1    Liu, J.2    Phillips, L.S.3
  • 7
    • 0034100823 scopus 로고    scopus 로고
    • Reversal of insulin-dependent diabetes using islet cells generated in vitro from pancreatic stem cells
    • Ramiya, V.K. et al. Reversal of insulin-dependent diabetes using islet cells generated in vitro from pancreatic stem cells. Nature Med. 6, 278-282 (2000).
    • (2000) Nature Med. , vol.6 , pp. 278-282
    • Ramiya, V.K.1
  • 8
    • 0034712022 scopus 로고    scopus 로고
    • Translating stem and progenitor cell biology to the clinic barriers and opportunities
    • Weissman, I.L. Translating stem and progenitor cell biology to the clinic barriers and opportunities. Science 287, 1442-1446 (2000).
    • (2000) Science , vol.287 , pp. 1442-1446
    • Weissman, I.L.1
  • 9
    • 0029027780 scopus 로고
    • Developmental biology of the pancreas
    • Slack, J.M. Developmental biology of the pancreas. Development 121, 1569-1580 (1995).
    • (1995) Development , vol.121 , pp. 1569-1580
    • Slack, J.M.1
  • 10
    • 0033534620 scopus 로고    scopus 로고
    • Glucose stimulates translocation of the homeodomaine transcription factor PDX-1 from the cytoplasm to the nucleus in pancreatic β cells
    • Macfarlane, W.D. et al. Glucose stimulates translocation of the homeodomaine transcription factor PDX-1 from the cytoplasm to the nucleus in pancreatic β cells. J. Biol. Chem. 274, 1011-1016 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 1011-1016
    • Macfarlane, W.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.