Proteasome inhibitors induce peroxisome proliferator-activated receptor transactivation through RXR accumulation and a protein kinase C-dependent pathway

Experimental Cell Research

Volumn 304, Issue 1, 2005, Pages 234-243

  Tsao, Wei Chia ^a   Wu, Hsiao Mei ^a   Chi, Kwan Hwa ^b   Chang, Ying Hsin ^a   Lin, Wan Wan ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Degradation; PKC; PPAR ; PPRE; Proteasome inhibitor; RXR

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALITRETINOIN; BENZOIC ACID DERIVATIVE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CALPHOSTIN C; CIGLITAZONE; ISOPROTEIN; MG 262; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHORBOL 12 ACETATE 13 MYRISTATE; PROTEASOME; PROTEIN KINASE C; PROTEINASE INHIBITOR; REACTIVE OXYGEN METABOLITE; RETINOID X RECEPTOR; RETINOID X RECEPTOR ALPHA; RETINOID X RECEPTOR BETA; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENZYME ACTIVATION; ENZYME ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; REPORTER GENE; SENSITIVITY ANALYSIS; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING;

EID: 13544261566     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.11.004     Document Type: Article

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