Distinct protein kinase C isozymes signal mitogenesis and apoptosis in human colon cancer cells

Gastroenterology

Volumn 117, Issue 4, 1999, Pages 848-857

  Weller, S G ^a   Klein, I K ^a   Penington, R C ^a   Karnes W E , Jr ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE C;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; COLON CANCER; COLORIMETRY; CONTROLLED STUDY; DNA DEGRADATION; ENZYME ACTIVATION; ENZYME ANALYSIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MITOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0032851481     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(99)70343-4     Document Type: Article

References (56)

1. LV Dekker RH Palmer PJ. Parker The protein kinase C and protein kinase C related gene families Curr Opin Struct Biol 5 1995 396 402
2. EM Deacon J Pongracz G Grif fiths JM. Lord Isoenzymes of protein kinase C: differential involvement in apoptosis and pathogenesis Mol Pathol 50 1997 124 131
3. K Orford C Crockett JP Jensen AM Weissman SW Byers Serine phosphorylation–regulated ubiquitination and degradation of beta-catenin J Biol Chem 272 1997 24735 24738
4. P Morrison K Takishima MR. Rosner Role of threonine residues in regulation of the epidermal growth factor receptor by protein kinase C and mitogen-activated protein kinase J Biol Chem 268 1993 15536 15543
5. R Marais Y Light C Mason H Paterson MF Olson CJ. Marshall Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C Science 280 1998 109 112
6. JP. Liu Protein kinase C and its substrates Mol Cell Endocrinol 116 1996 1 29
7. LV Dekker PJ Parker Protein kinase C—a question of specificity Trends Biochem Sci 19 1994 73 77
8. AC. Newton Protein kinase C: structure, function, and regulation J Biol Chem 270 1995 28495 28498
9. YH Jiang HM Aukema LA Davidson JR Lupton RS. Chapkin Localization of protein kinase C isozymes in rat colon Cell Growth Differ 6 1995 1381 1386
10. P Kahl-Rainer R Sedivy B. Marian Protein kinase C tissue localization in human colonic tumors suggests a role for adenoma growth control Gastroenterology 110 1996 1753 1759
11. G Verstovsek A Byrd MR Frey NJ Petrelli JD. Black Colonocyte differentiation is associated with increased expression and altered distribution of protein kinase C isozymes Gastroenterology 115 1998 75 85
12. MIN mice Gastroenterology 114 1998 G2576
13. M. Lipkin Proliferation and differentiation of normal and neoplastic cells in the colon of man Cancer 28 1971 38 40
14. SF Moss TC Liu A Petrotos TM Hsu LI Gold PR. Holt Inward growth of colonic adenomatous polyps Gastroenterology 111 1996 1425 1432
15. S Doi D Goldstein H Hug IB. Weinstein Expression of multiple isoforms of protein kinase C in normal human colon mucosa and colon tumors and decreased levels of protein kinase C beta and eta mRNAs in the tumors Mol Carcinog 11 1994 197 203
16. MF Levy J Pocsidio JG Guillem K Forde P LoGerfo IB. Weinstein Decreased levels of protein kinase C enzyme activity and protein kinase C mRNA in primary colon tumors Dis Colon Rectum 36 1993 913 921
17. R Kopp B Noelke G Sauter FW Schildberg G Paumgartner A. Pfeiffer Altered protein kinase C activity in biopsies of human colonic adenomas and carcinomas Cancer Res 51 1991 205 210
18. Y Sakanoue T Hatada M Kusunoki H Yanagi T Yamamura J. Utsunomiya Protein kinase C activity as marker for colorectal cancer Int J Cancer 48 1991 803 806
19. DR Goldstein AM Cacace IB. Weinstein Overexpression of protein kinase C beta 1 in the SW480 colon cancer cell line causes growth suppression Carcinogenesis 16 1995 1121 1126
20. PM Choi KM Tchou-Wong IB. Weinstein Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression Mol Cell Biol 10 1990 4650 4657
21. S Sauma Z Yan S Ohno E. Friedman Protein kinase C beta 1 and protein kinase C beta 2 activate p57 mitogen-activated protein kinase and block differentiation in colon carcinoma cells Cell Growth Differ 7 1996 587 594
22. B Scaglione-Sewell C Abraham M Bissonnette SF Skarosi J Hart NO Davidson RK Wali BH Davis M Sitrin TA. Brasitus Decreased PKC-alpha expression increases cellular proliferation, decreases differentiation, and enhances the transformed pheno-type of CaCo-2 cells Cancer Res 58 1998 1074 1081
23. Kip1 Gastroenterology 112 1997 A651 (abstr)
24. H Mischak JA Goodnight W Kolch G Martiny-Baron C Schaechtle MG Kazanietz PM Blumberg JH Pierce JF Mushinski Overex-pression of protein kinase C–delta and–epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity J Biol Chem 268 1993 6090 6096
25. GP Perletti M Folini HC Lin H Mischak F Piccinini AJ. Tashjian Overexpression of protein kinase C epsilon is oncogenic in rat colonic epithelial cells Oncogene 12 1996 847 854
26. T Ghayur M Hugunin RV Talanian S Ratnofsky C Quinlan Y Emoto P Pandey R Datta Y Huang S Kharbanda H Allen R Kamen W Wong D Kufe Proteolytic activation of protein kinase C delta by an ICE/CED 3–like protease induces characteristics of apoptosis J Exp Med 184 1996 2399 2404
27. R Datta H Kojima K Yoshida D Kufe Caspase-3–mediated cleavage of protein kinase C theta in induction of apoptosis J Biol Chem 272 1997 20317 20320
28. NR Murray AP. Fields Atypical protein kinase C iota protects human leukemia cells against drug-induced apoptosis J Biol Chem 272 1997 27521 27524
29. MG Kazanietz LB Areces A Bahador H Mischak J Goodnight JF Mushinski PM. Blumberg Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes Mol Pharmacol 44 1993 298 307
30. K Nishikawa A Toker FJ Johannes Z Songyang LC. Cantley Determination of the specific substrate sequence motifs of protein kinase C isozymes J Biol Chem 272 1997 952 960
31. D Mochly-Rosen AS. Gordon Anchoring proteins for protein kinase C: a means for isozyme selectivity FASEB J 12 1998 35 42
32. D. Mochly-Rosen Localization of protein kinases by anchoring proteins: a theme in signal transduction Science 268 1995 247 250
33. J-G Park HK Oie PH Sugarbaker JG Henslee T-R Chen BE Johnson AF. Gazdar Characteristics of cell lines established from human colorectal carcinoma Cancer Res 47 1987 6710 6718
34. WE Karnes Jr JH Walsh SV Wu RS Kim MG Martin HC Wong J Mendelsohn J-G Park F. Cuttitta Autonomous proliferation of colon carcinoma cells that co-express transforming growth factor-alpha and its receptor: variable effects of receptor-blocking antibody Gastroenterology 102 1992 474 485
35. G Griffiths B Garrone E Deacon P Owen J Pongracz G Mead A Bradwell D Watters J Lord The polyether bistratene A activates protein kinase C–delta and induces growth arrest in HL60 cells Biochem Biophys Res Commun 222 1996 802 808
36. WE Karnes Jr SG Weller PN Adjei TJ Kottke KS Glenn GJ Gores SH. Kaufmann Inhibition of epidermal growth factor receptor kinase induces protease-dependent apoptosis in human colon cancer cells Gastroenterology 114 1998 930 939
37. DJ. Winterbourne Chemical assays for proteins JM Graham JA Higgins Biomembrane protocols I. Isolation and analysis. 1993 Humana Totawa, NJ 197 202
38. kip1 and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells J Biol Chem 272 1997 9424 9435
39. G Martiny-Baron MG Kazanietz H Mischak PM Blumberg G Kochs Hug D Marme C. Schachtele Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976 J Biol Chem 268 1993 9194 9197
40. D Toullec P Pianetti H Coste P Bellevergue T Grand-Perret M Ajakane V Baudet P Boissin E Boursier F. Loriolle The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C J Biol Chem 266 1991 15771 15781
41. A Asada Y Zhao S Kondo M. Iwata Induction of thymocyte apoptosis by Ca2+-independent protein kinase C (nPKC) activation and its regulation by calcineurin activation J Biol Chem 273 1998 28392 28398
42. WJ Ryves AT Evans AR Olivier PJ Parker FJ. Evans Activation of the PKC-isotypes alpha, beta 1, gamma, delta and epsilon by phorbol esters of different biological activities FEBS Lett 288 1991 5 9
43. R Roivainen RO. Messing The phorbol derivatives thymeleatoxin and 12-deoxyphorbol-13-O-phenylacetate-10-acetate cause trans-location and down-regulation of multiple protein kinase C isozymes FEBS Lett 319 1993 31 34
44. CM Hasler G Acs PM. Blumberg Specific binding to protein kinase C by ingenol and its induction of biological responses Cancer Res 52 1992 202 208
45. MJ Caloca N Fernandez NE Lewin D Ching R Modali PM Blumberg MG. Kazanietz Beta2-chimaerin is a high affinity receptor for the phorbol ester tumor promoters J Biol Chem 272 1997 26488 26496
46. C Branting R Toftgard IP Hallstrom J. Rafter Role of protein kinase C in growth stimulation of primary mouse colonic epithelial cells In Vitro Cell Dev Biol 31 1995 790 795
47. E Friedman P Isaksson J Rafter B Marian S Winawer H. Newmark Fecal diglycerides as selective endogenous mitogens for premalignant and malignant human colonic epithelial cells Cancer Res 49 1989 544 548
48. JA Frost TD Geppert MH Cobb JR Feramisco A requirement for extracellular signal–regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum Proc Natl Acad Sci USA 91 1994 3844 3848
49. D Schaap J van der Wal LR Howe CJ Marshall WJ. van Blitterswijk A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras J Biol Chem 268 1993 20232 20236
50. P Dent DB Reardon DK Morrison TW Sturgill Regulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras-independent mechanisms in vitro Mol Cell Biol 15 1995 4125 4135
51. S Sauma E. Friedman Increased expression of protein kinase C beta activates ERK3 J Biol Chem 271 1996 11422 11426
52. R Emkey CR Kahn Cross-talk between phorbol ester–mediated signaling and tyrosine kinase proto-oncogenes. I. Activation of protein kinase C stimulates tyrosine phosphorylation and activation of ErbB2 and ErbB3 J Biol Chem 272 1997 31172 31181
53. AE Levine Involvement of protein kinase C and an elastase-like enzyme in the processing of transforming growth factor–alpha in human colon carcinoma cell lines Int J Cancer 58 1994 129 134
54. G Ramesh AE Levine Pro-transforming growth factor-alpha processing in human colon carcinoma cells—role of protein kinase C Int J Cancer 62 1995 492 497
55. M Ueffing J Lovric A Philipp H Mischak W. Kolch Protein kinase C-epsilon associates with the Raf-1 kinase and induces the production of growth factors that stimulate Raf-1 activity Oncogene 15 1997 2921 2927
56. S Weller IG-DR Klein G Bogatcheva RJ Coffey Jr WE Karnes Jr. PKC agonists stimulate mitogenesis of SNU-C4 colon cancer cells by augmenting autocrine stimulation of epidermal growth factor receptor Gastroenterology 114 1998 G2906 (abstr)