Alterations in protein kinase C isoenzyme expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy

Molecular and Cellular Biochemistry

Volumn 242, Issue 1-2, 2003, Pages 145-152

  Bayer, Allison L ^a   Heidkamp, Maria C ^a   Patel, Nehu ^a   Porter, Michael ^a   Engnam, Steve ^a   Samarel, Allen M ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Autophosphorylation; Cardiomyocytes; Heart failure; Signal transduction

Indexed keywords

ISOENZYME; MONOCLONAL ANTIBODY; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA COARCTATION; ARTICLE; AUTOPHOSPHORYLATION; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART FAILURE; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HYPERTENSION; IN VIVO STUDY; MALE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; RAT STRAIN; TIME; WESTERN BLOTTING;

ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; ISOENZYMES; MALE; MYOCARDIAL CONTRACTION; PHOSPHORYLATION; PRESSURE; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN KINASE C-DELTA; PROTEIN KINASE C-EPSILON; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0037281147     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021106232511     Document Type: Article

References (32)

1. Bogoyevitch MA, Sugden PH: The role of protein kinases in adaptational growth of the heart. Int J Biochem Cell Biol 28: 1-12, 1996
2. Dunnmon PM, Iwaki K, Henderson SA, Sen A, Chien KR: Phorbol esters induce immediate-early genes and activate cardiac gene transcription in neonatal rat myocardial cells. J Mol Cell Cardiol 22: 901-910, 1990
3. Samarel AM, Engelmann GL: Contractile activity modulates myosin heavy chain-β expression in neonatal rat heart cells. Am J Physiol 261: H1067-HI077, 1991
4. Komuro I, Katoh Y, Kaida T, Shibazaki Y, Kurabayashi M, Hoh E, Takaku F, Yazaki Y. Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activation. J Biol Chem 266: 1265-1268, 1991
5. Kariya K, Karns LR, Simpson PC: Expression of a constitutively activated mutant of the β-isozyme of protein kinase C in cardiac myocytes stimulates the promoter of the β-myosin heavy chain isogene. J Biol Chem 266: 10023-10026, 1991
6. Allo SN, Carl LL, Morgan HE: Acceleration of growth of cultured cardiomyocytes and translocation of protein kinase C. Am J Physiol 263: C319-C325, 1992
7. Sadoshima J, Takahashi T, Jahn L, Izumo S: Roles of mechano-sensitive ion channels, cytoskeleton, and contractile activity in stretch-induced immediate-early gene expression and hypertrophy of cardiac myocytes. Proc Natl Acad Sci USA 89: 9905-9909, 1992
8. Rybin VO, Steinberg SF: Protein kinase C isoform expression and regulation in the developing rat heart. Circ Res 74: 299-309, 1994
9. Clerk A, Bogoyevitch MA, Fuller SJ, Lazou A, Parker PJ, Sugden PH: Expression of protein kinase C isoforms during cardiac ventricular development. Am J Physiol 269: H1087-H1097, 1995
10. Ron D, Kazanietz MG: New insights into the regulation of protein kinase C and novel phorbol ester receptors. FASEB J 13: 1658-1676, 1999
11. Parekh DB, Ziegler W, Parker PJ: Multiple pathways control protein kinase C phosphorylation. EMBO J 19: 496-503, 2000
12. Dempsey EC, Newton AC, Mochly-Rosen D, Fields AP, Reyland ME, Insel PA, Messing RO: Protein kinase C isozymes and the regulation of diverse cell responses. Am J Physiol Lung Cell Mol Physiol 279: L429-L438, 2000
13. Gu X, Bishop SP: Increased protein kinase C and isozyme redistribution in pressure-overload cardiac hypertrophy in the rat. Circ Res 75: 926-931, 1994
14. Jalili T, Takeishi Y, Song G, Ball NA, Howles G, Walsh RA: PKC translocation without changes in Gαq and PLC-β protein abundance in cardiac hypertrophy and failure. Am J Physiol 277: H2298-H2304, 1999
15. 2+-sensitive isoforms in the failing human heart. Circulation 99: 384-391, 1999
16. Eleftheriades EG, Durand JB, Ferguson AG, Engelmann GL, Jones SB, Samarel AM: Regulation of procollagen metabolism in the pressure-overloaded rat heart. J Clin Invest 91: 1113-1122, 1993
17. 2+-ATPase during progression of left ventricular hypertrophy. Am J Physiol 272: H2416-H2424, 1997
18. 2+ fluxes, and sarcoplasmic reticulum loading in pressure-overload hypertrophy. Am J Physiol 272: H2425-H2435, 1997
19. McCall E, Ginsburg KS, Bassani RA, Shannon TR, Qi M, Samarel AM, Bers DM: Ca flux, contractility, and excitation-contraction coupling in hypertrophic rat ventricular myocytes. Am J Physiol 274: H1348-H1360, 1998
20. Imamura T, McDermott PJ, Kent RL, Nagatsu M, Cooper GT, Carabello BA: Acute changes in myosin heavy chain synthesis rate in pressure versus volume overload. Circ Res 75: 418-425, 1994
21. Chen L, Hahn H, Wu G, Chen CH, Liron T, Schechtman D, Cavallaro G, Banci L, Guo Y, Bolli R, Dorn GW, Mochly-Rosen D: Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and EPKC. Proc Natl Acad Sci USA 98: 11114-11119, 2001
22. Mochly-Rosen D, Wu G, Hahn H, Osinska H, Liron T, Lorenz JN, Yatani A, Robbins J, Dorn GW: Cardiotrophic effects of protein kinase Cε: Analysis by in vivo modulation of PKCε translocation. Circ Res 86:1173-1179, 2000
23. Strait JB, Samarel AM: Isoenzyme-specific protein kinase C and c-Jun N-terminal kinase activation by electrically stimulated contraction of neonatal rat ventricular myocytes. J Mol Cell Cardiol 32: 1553-1566, 2000
24. Strait JB, Martin JL, Bayer A, Mestril R, Eble DM, Samarel AM: Role of protein kinase C-ε in hypertrophy of cultured neonatal rat ventricular myocytes. Am J Physiol Heart Circ Physiol 280: H756-H766, 2001
25. Heidkamp MC, Bayer AL, Martin JL, Samarel AM: Differential activation of mitogen-activated protein kinase cascades and apoptosis by protein kinase C ε and δ in neonatal rat ventricular myocytes. Circ Res 89:882-890, 2001
26. Takeishi Y, Ping P, Bolli R, Kirkpatrick DL, Hoit BD, Walsh RA: Transgenic overexpression of constitutively active protein kinase Cε: causes concentric cardiac hypertrophy. Circ Res 86: 1218-1223, 2000
27. Bogoyevitch MA, Parker PJ, Sugden PH: Characterization of protein kinase C isotype expression in adult rat heart. Protein kinase C-ε is a major isotype present, and it is activated by phorbol esters, epinephrine, and endothelin. Circ Res 72: 757-767, 1993
28. Clerk A, Bogoyevitch MA, Parker PJ, Sugden PH: Down-regulation of protein kinase C isotypes during postnatal development of rat heart. Biochem Soc Trans 21: 385S, 1993
29. 2 isoform in myocardium causes cardiomyopathy. Proc Natl Acad Sci USA 94: 9320-9325, 1997
30. Puceat M, Hilal-Dandan R, Strulovici B, Branton LL, Brown JH: Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes. J Biol Chem 269: 16938-16944, 1994
31. Clerk A, Bogoyevitch MA, Anderson MB, Sugden PH: Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen- activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. J Biol Chem 269: 32848-32857, 1994
32. 2+-dependent transgenic model of cardiac hypertrophy: A role for protein kinase Cα. Circulation 103: 140-147, 2001