-
1
-
-
0029900303
-
Degeneration and regeneration of axons in the lesioned spinal cord
-
Schwab M.E., Bartholdi D. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol. Rev. 76:1996;319-370.
-
(1996)
Physiol. Rev.
, vol.76
, pp. 319-370
-
-
Schwab, M.E.1
Bartholdi, D.2
-
2
-
-
0037039823
-
Repairing the injured spinal cord
-
Schwab M.E. Repairing the injured spinal cord. Science. 295:2002;1029-1031.
-
(2002)
Science
, vol.295
, pp. 1029-1031
-
-
Schwab, M.E.1
-
3
-
-
0035893632
-
Epidemiology, demographics, and pathophysiology of acute spinal cord injury
-
Sekhon L.H.S., Fehlings M.G. Epidemiology, demographics, and pathophysiology of acute spinal cord injury. Spine. 26:2003;S2-S12.
-
(2003)
Spine
, vol.26
-
-
Sekhon, L.H.S.1
Fehlings, M.G.2
-
4
-
-
0019856865
-
Axonal elongation into peripheral nervous system 'bridges' after central nervous system injury in adult rats
-
David S., Aguayo A.J. Axonal elongation into peripheral nervous system 'bridges' after central nervous system injury in adult rats. Science. 214:1981;931-933.
-
(1981)
Science
, vol.214
, pp. 931-933
-
-
David, S.1
Aguayo, A.J.2
-
5
-
-
0021930886
-
Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors
-
Schwab M.E., Thoenen H. Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors. J. Neurosci. 5:1985;2415-2423.
-
(1985)
J. Neurosci.
, vol.5
, pp. 2415-2423
-
-
Schwab, M.E.1
Thoenen, H.2
-
6
-
-
0025017637
-
Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors
-
Schnell L., Schwab M.E. Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature. 343:1990;269-272.
-
(1990)
Nature
, vol.343
, pp. 269-272
-
-
Schnell, L.1
Schwab, M.E.2
-
7
-
-
0034331170
-
Regeneration of lesioned corticospinal tract fibers in the adult rat induced by a recombinant, humanized IN-1 antibody fragment
-
Brösamle C., Huber A.B., Fiedler M., Skerra A., Schwab M.E. Regeneration of lesioned corticospinal tract fibers in the adult rat induced by a recombinant, humanized IN-1 antibody fragment. J. Neurosci. 20:2000;8061-8068.
-
(2000)
J. Neurosci.
, vol.20
, pp. 8061-8068
-
-
Brösamle, C.1
Huber, A.B.2
Fiedler, M.3
Skerra, A.4
Schwab, M.E.5
-
8
-
-
0033231307
-
A therapeutic vaccine approach to stimulate axon regeneration in the adult mammalian spinal cord
-
Huang D.W., McKerracher L., Braun P.E., David S. A therapeutic vaccine approach to stimulate axon regeneration in the adult mammalian spinal cord. Neuron. 24:1999;639-647.
-
(1999)
Neuron
, vol.24
, pp. 639-647
-
-
Huang, D.W.1
McKerracher, L.2
Braun, P.E.3
David, S.4
-
9
-
-
0023967246
-
Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter
-
Caroni P., Schwab M.E. Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter. Neuron. 1:1988;85-96.
-
(1988)
Neuron
, vol.1
, pp. 85-96
-
-
Caroni, P.1
Schwab, M.E.2
-
10
-
-
0032563211
-
Identification and characterization of a bovine neurite growth inhibitor (bNI-220)
-
Spillmann A.A., Bandtlow C.E., Lottspeich F., Keller F., Schwab M.E. Identification and characterization of a bovine neurite growth inhibitor (bNI-220). J. Biol. Chem. 273:1998;19283-19293.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19283-19293
-
-
Spillmann, A.A.1
Bandtlow, C.E.2
Lottspeich, F.3
Keller, F.4
Schwab, M.E.5
-
11
-
-
0034719513
-
Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1
-
Chen M.S., Huber A.B., Van Der Haar M.E., Frank M., Schnell L., Spillmann A.A., Christ F., Schwab M.E. Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature. 403:2000;434-439.
-
(2000)
Nature
, vol.403
, pp. 434-439
-
-
Chen, M.S.1
Huber, A.B.2
Van Der Haar, M.E.3
Frank, M.4
Schnell, L.5
Spillmann, A.A.6
Christ, F.7
Schwab, M.E.8
-
12
-
-
0034719371
-
Identification of the Nogo inhibitor of axon regeneration as a reticulon protein
-
Grandpré T., Nakamura F., Vartanian T., Strittmatter S.M. Identification of the Nogo inhibitor of axon regeneration as a reticulon protein. Nature. 403:2000;439-444.
-
(2000)
Nature
, vol.403
, pp. 439-444
-
-
Grandpré, T.1
Nakamura, F.2
Vartanian, T.3
Strittmatter, S.M.4
-
13
-
-
0034719477
-
Inhibitor of neurite outgrowth in humans
-
Prinhja R., Moore S.E., Vinson M., Blake S., Morrow R., Christie G., Michalovich D., Simmons D.L., Walsh F.S. Inhibitor of neurite outgrowth in humans. Nature. 403:2000;383-384.
-
(2000)
Nature
, vol.403
, pp. 383-384
-
-
Prinhja, R.1
Moore, S.E.2
Vinson, M.3
Blake, S.4
Morrow, R.5
Christie, G.6
Michalovich, D.7
Simmons, D.L.8
Walsh, F.S.9
-
14
-
-
0033570319
-
Bovine CNS myelin contains neurite growth-inhibitory activity associated with chondroitin sulfate proteoglycan
-
Niederöst B., Zimmermann D.R., Schwab M.E., Bandtlow C.E. Bovine CNS myelin contains neurite growth-inhibitory activity associated with chondroitin sulfate proteoglycan. J. Neurosci. 19:1999;8979-8989.
-
(1999)
J. Neurosci.
, vol.19
, pp. 8979-8989
-
-
Niederöst, B.1
Zimmermann, D.R.2
Schwab, M.E.3
Bandtlow, C.E.4
-
15
-
-
0141499228
-
Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS
-
Filbin M.T. Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS. Nat. Rev. Neurosci. 4:2003;703-713.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 703-713
-
-
Filbin, M.T.1
-
16
-
-
0042858516
-
Molecular approaches to spinal cord repair
-
David S., Lacroix S. Molecular approaches to spinal cord repair. Annu. Rev. Neurosci. 26:2003;411-440.
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 411-440
-
-
David, S.1
Lacroix, S.2
-
18
-
-
0036663013
-
Localization of Nogo-A and Nogo-66 receptor proteins at sites of axon-myelin and synaptic contact
-
•], this study maps the distribution of Nogo-A in the adult and developing nervous system. In white matter, Nogo-A is localized on the innermost adaxonal and the outermost myelin membranes only. The Nogo receptor NgR is a neuronal protein. Developing neurons also express Nogo-A.
-
•], this study maps the distribution of Nogo-A in the adult and developing nervous system. In white matter, Nogo-A is localized on the innermost adaxonal and the outermost myelin membranes only. The Nogo receptor NgR is a neuronal protein. Developing neurons also express Nogo-A.
-
(2002)
J. Neurosci.
, vol.22
, pp. 5505-5515
-
-
Wang, X.1
Chun, S.-J.2
Treloar, H.3
Vartanian, T.4
Greer, C.A.5
Strittmatter, S.M.6
-
19
-
-
0034988117
-
Nogo mRNA expression in adult and fetal human and rat nervous tissue and in weight drop injury
-
Josephson A., Widenfalk J., Widmer H.W., Olson L., Spenger C. Nogo mRNA expression in adult and fetal human and rat nervous tissue and in weight drop injury. Exp. Neurol. 169:2001;319-328.
-
(2001)
Exp. Neurol.
, vol.169
, pp. 319-328
-
-
Josephson, A.1
Widenfalk, J.2
Widmer, H.W.3
Olson, L.4
Spenger, C.5
-
21
-
-
0038799728
-
A reticular rhapsody: Phylogenic evolution and nomenclature of the RTN/Nogo gene family
-
Oertle T., Klinger M., Stuermer C.A.O., Schwab M.E. A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family. FASEB J. 17:2003;1238-1247.
-
(2003)
FASEB J.
, vol.17
, pp. 1238-1247
-
-
Oertle, T.1
Klinger, M.2
Stuermer, C.A.O.3
Schwab, M.E.4
-
22
-
-
0038384089
-
Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions
-
Nogo-A has at least two active sites for inhibition of neurite growth: a site specific to Nogo-A, and the C-terminal Nogo-66 region that is common to Nogo-A, -B and -C. Both sites are exposed to the extracellular space on the surface of cultured living oligodendrocytes.
-
Oertle T., van der Haar M.E., Bandtlow C.E., Robeva A., Burfeind P., Buss A., Huber A.B., Simonen M., Schnell L., Brösamle C., et al. Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions. J. Neurosci. 23:2003;5393-5406 Nogo-A has at least two active sites for inhibition of neurite growth: a site specific to Nogo-A, and the C-terminal Nogo-66 region that is common to Nogo-A, -B and -C. Both sites are exposed to the extracellular space on the surface of cultured living oligodendrocytes.
-
(2003)
J. Neurosci.
, vol.23
, pp. 5393-5406
-
-
Oertle, T.1
Van Der Haar, M.E.2
Bandtlow, C.E.3
Robeva, A.4
Burfeind, P.5
Buss, A.6
Huber, A.B.7
Simonen, M.8
Schnell, L.9
Brösamle, C.10
-
23
-
-
0037198689
-
Nogo-66 receptor antagonist peptide promotes axonal regeneration
-
The first 40 amino acids of the C-terminal extracellular loop of Nogo ('Nogo-66') act as an antagonist on the Nogo-66 receptor NgR. In vivo application of this 40-residue peptide in adult rats with partial spinal cord lesions enhances corticospinal tract regeneration, serotonergic-fibre density and locomotor recovery.
-
Grandpré T., Li S., Strittmatter S.M. Nogo-66 receptor antagonist peptide promotes axonal regeneration. Nature. 417:2002;547-551 The first 40 amino acids of the C-terminal extracellular loop of Nogo ('Nogo-66') act as an antagonist on the Nogo-66 receptor NgR. In vivo application of this 40-residue peptide in adult rats with partial spinal cord lesions enhances corticospinal tract regeneration, serotonergic-fibre density and locomotor recovery.
-
(2002)
Nature
, vol.417
, pp. 547-551
-
-
Grandpré, T.1
Li, S.2
Strittmatter, S.M.3
-
24
-
-
0035905799
-
Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration
-
Fournier A.E., Grandpre T., Strittmatter S.M. Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature. 409:2001;341-346.
-
(2001)
Nature
, vol.409
, pp. 341-346
-
-
Fournier, A.E.1
Grandpre, T.2
Strittmatter, S.M.3
-
25
-
-
0038325765
-
Structure of the Nogo receptor ectodomain: A recognition module implicated in myelin inhibition
-
He X.L., Bazan J.F., McDermott G., Park J.B., Wang K., Tessier-Lavigne M., He Z., Garcia K.C. Structure of the Nogo receptor ectodomain: a recognition module implicated in myelin inhibition. Neuron. 38:2003;177-185.
-
(2003)
Neuron
, vol.38
, pp. 177-185
-
-
He, X.L.1
Bazan, J.F.2
McDermott, G.3
Park, J.B.4
Wang, K.5
Tessier-Lavigne, M.6
He, Z.7
Garcia, K.C.8
-
26
-
-
0038263895
-
Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins
-
Barton W.A., Liu B.P., Tzvetkova D., Jeffrey P.D., Fournier A.E., Sah D., Cate R., Strittmatter S.M., Nikolov D.B. Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. EMBO J. 22:2003;3291-3302.
-
(2003)
EMBO J.
, vol.22
, pp. 3291-3302
-
-
Barton, W.A.1
Liu, B.P.2
Tzvetkova, D.3
Jeffrey, P.D.4
Fournier, A.E.5
Sah, D.6
Cate, R.7
Strittmatter, S.M.8
Nikolov, D.B.9
-
27
-
-
0344445378
-
Signaling mechanisms of the myelin inhibitors of axon regeneration
-
Yiu G., He Z. Signaling mechanisms of the myelin inhibitors of axon regeneration. Curr. Opin. Neurobiol. 13:2003;1-7.
-
(2003)
Curr. Opin. Neurobiol.
, vol.13
, pp. 1-7
-
-
Yiu, G.1
He, Z.2
-
28
-
-
0036897583
-
A p75 NTR and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein
-
Wong S.T., Henley J.R., Kanning K.C., Huang K., Bothwell M., Poo M.-M. A p75 NTR and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein. Nat. Neurosci. 5:2002;1302-1308.
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 1302-1308
-
-
Wong, S.T.1
Henley, J.R.2
Kanning, K.C.3
Huang, K.4
Bothwell, M.5
Poo, M.-M.6
-
29
-
-
0027514515
-
Role of intracellular calcium in NI-35-evoked collapse of neuronal growth cones
-
Bandtlow C.E., Schmidt M.F., Hassinger T.D., Schwab M.E., Kater S.B. Role of intracellular calcium in NI-35-evoked collapse of neuronal growth cones. Science. 259:1993;80-83.
-
(1993)
Science
, vol.259
, pp. 80-83
-
-
Bandtlow, C.E.1
Schmidt, M.F.2
Hassinger, T.D.3
Schwab, M.E.4
Kater, S.B.5
-
30
-
-
0036895744
-
Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1
-
Niederöst B., Oertle T., Fritsche J., Mckinney R.A., Bandtlow C.E. Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1. J Neurosci. 22:2002;10368-10376.
-
(2002)
J Neurosci
, vol.22
, pp. 10368-10376
-
-
Niederöst, B.1
Oertle, T.2
Fritsche, J.3
McKinney, R.A.4
Bandtlow, C.E.5
-
31
-
-
0037443069
-
Rho kinase inhibition enhances axonal regeneration in the injured CNS
-
Fournier A.E., Takizawa B.T., Strittmatter S.M. Rho kinase inhibition enhances axonal regeneration in the injured CNS. J. Neurosci. 23:2003;1416-1423.
-
(2003)
J. Neurosci.
, vol.23
, pp. 1416-1423
-
-
Fournier, A.E.1
Takizawa, B.T.2
Strittmatter, S.M.3
-
32
-
-
0036878139
-
An engineered IN-1 Fab fragment with improved affinity for the Nogo-A axonal growth inhibitor permits immunochemical detection and shows enhanced neutralizing acitivty
-
Fiedler M., Horn C., Bandtlow C., Schwab M.E., Skerra A. An engineered IN-1 Fab fragment with improved affinity for the Nogo-A axonal growth inhibitor permits immunochemical detection and shows enhanced neutralizing acitivty. Protein Eng. 15:2002;931-941.
-
(2002)
Protein Eng.
, vol.15
, pp. 931-941
-
-
Fiedler, M.1
Horn, C.2
Bandtlow, C.3
Schwab, M.E.4
Skerra, A.5
-
33
-
-
0038076000
-
Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury
-
•].
-
•].
-
(2003)
Neuron
, vol.38
, pp. 201-211
-
-
Simonen, M.1
Pedersen, V.2
Weinmann, O.3
Schnell, L.4
Buss, A.5
Ledermann, B.6
Christ, F.7
Van Der Putten, M.8
Schwab, M.E.9
-
36
-
-
0037109760
-
Truncated soluble Nogo receptor binds Nogo-66 and blocks inhibition of axon growth by myelin
-
Fournier A.E., Gould G.C., Liu B.P., Strittmatter S.M. Truncated soluble Nogo receptor binds Nogo-66 and blocks inhibition of axon growth by myelin. J. Neurosci. 22:2002;8876-8883.
-
(2002)
J. Neurosci.
, vol.22
, pp. 8876-8883
-
-
Fournier, A.E.1
Gould, G.C.2
Liu, B.P.3
Strittmatter, S.M.4
-
37
-
-
0036703599
-
Rho signaling pathway targeted to promote spinal cord repair
-
Dergham P., Ellezam B., Essagian C., Adevissian H., Lubell W.D., McKerracher L. Rho signaling pathway targeted to promote spinal cord repair. J. Neurosci. 22:2002;6570-6577.
-
(2002)
J. Neurosci.
, vol.22
, pp. 6570-6577
-
-
Dergham, P.1
Ellezam, B.2
Essagian, C.3
Adevissian, H.4
Lubell, W.D.5
McKerracher, L.6
-
38
-
-
0037356723
-
Suppression of Rho-kinase activity promotes axonal growth on inhibitory CNS substrates
-
Borisoff J.F., Chan C.C.M., Hiebert G.W., Oschipok L., Robertson G.S., Zamboni R., Steeves J.D., Tetzlaff W. Suppression of Rho-kinase activity promotes axonal growth on inhibitory CNS substrates. Mol. Cell. Neurosci. 22:2003;405-416.
-
(2003)
Mol. Cell. Neurosci.
, vol.22
, pp. 405-416
-
-
Borisoff, J.F.1
Chan, C.C.M.2
Hiebert, G.W.3
Oschipok, L.4
Robertson, G.S.5
Zamboni, R.6
Steeves, J.D.7
Tetzlaff, W.8
-
39
-
-
0037104645
-
Arginase I and Polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth on MAG and myelin in vitro
-
Cai D., Deng K., Mellado W., Lee J., Ratan R.R., Filbin M.T. Arginase I and Polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth on MAG and myelin in vitro. Neuron. 35:2002;711-719.
-
(2002)
Neuron
, vol.35
, pp. 711-719
-
-
Cai, D.1
Deng, K.2
Mellado, W.3
Lee, J.4
Ratan, R.R.5
Filbin, M.T.6
-
40
-
-
0034654086
-
Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured Purkinje cell axons
-
Buffo A., Zagrebelsky M., Huber A.B., Skerra A., Schwab M.E., Strata P., Rossi F. Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured Purkinje cell axons. J. Neurosci. 20:2000;2275-2286.
-
(2000)
J. Neurosci.
, vol.20
, pp. 2275-2286
-
-
Buffo, A.1
Zagrebelsky, M.2
Huber, A.B.3
Skerra, A.4
Schwab, M.E.5
Strata, P.6
Rossi, F.7
-
41
-
-
0037316286
-
Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats
-
Wiessner C., Bareyre F.M., Allegrini P.R., Mir A.K., Frentzel S., Zurini M., Schnell L., Oertle T., Schwab M.E. Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats. J. Cereb. Blood Flow Metab. 23:2003;154-165.
-
(2003)
J. Cereb. Blood Flow Metab.
, vol.23
, pp. 154-165
-
-
Wiessner, C.1
Bareyre, F.M.2
Allegrini, P.R.3
Mir, A.K.4
Frentzel, S.5
Zurini, M.6
Schnell, L.7
Oertle, T.8
Schwab, M.E.9
-
42
-
-
85030888350
-
-
Program No. 678.9, 2003 Abstract Viewer & Itinerary Planner. Washington DC: Society for Neuroscience.
-
Schnell L, Liebscher T, Weinmann O, Schneider R, Scholl J, Klusman I, Mir A, Schwab ME: Lesioned axons regenerate in the adult rat spinal cord when treated with antibodies against Nogo-A. Program No. 678.9, 2003 Abstract Viewer & Itinerary Planner. Washington DC: Society for Neuroscience.
-
Lesioned Axons Regenerate in the Adult Rat Spinal Cord When Treated with Antibodies Against Nogo-A
-
-
Schnell, L.1
Liebscher, T.2
Weinmann, O.3
Schneider, R.4
Scholl, J.5
Klusman, I.6
Mir, A.7
Schwab, M.E.8
-
43
-
-
0032189056
-
Retrograde regulation of growth-associated gene expression in adult rat Purkinje cells by myelin-associated neurite growth inhibitory proteins
-
Zagrebelsky M., Buffo A., Skerra A., Schwab M.E., Strata P., Rossi F. Retrograde regulation of growth-associated gene expression in adult rat Purkinje cells by myelin-associated neurite growth inhibitory proteins. J. Neurosci. 18:1998;7912-7929.
-
(1998)
J. Neurosci.
, vol.18
, pp. 7912-7929
-
-
Zagrebelsky, M.1
Buffo, A.2
Skerra, A.3
Schwab, M.E.4
Strata, P.5
Rossi, F.6
-
44
-
-
0037104719
-
Long-lasting sprouting and gene expression changes induced by the monoclonal antibody IN-1 in the adult spinal cord
-
Bareyre F.M., Haudenschild B., Schwab M.E. Long-lasting sprouting and gene expression changes induced by the monoclonal antibody IN-1 in the adult spinal cord. J. Neurosci. 22:2002;7097-7110.
-
(2002)
J. Neurosci.
, vol.22
, pp. 7097-7110
-
-
Bareyre, F.M.1
Haudenschild, B.2
Schwab, M.E.3
-
45
-
-
0028867947
-
Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors
-
Bregman B.S., Kunkel-Bagden E., Schnell L., Dai H.N., Gao D., Schwab M.E. Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature. 378:1995;498-501.
-
(1995)
Nature
, vol.378
, pp. 498-501
-
-
Bregman, B.S.1
Kunkel-Bagden, E.2
Schnell, L.3
Dai, H.N.4
Gao, D.5
Schwab, M.E.6
-
46
-
-
0036196245
-
Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN-1 antibody treatment in the adult rat
-
Papadopoulos C.M., Tsai S.-Y., Aslbiei T., O'Brien T.E., Schwab M.E., Kartje G.L. Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN-1 antibody treatment in the adult rat. Ann. Neurol. 51:2002;433-441.
-
(2002)
Ann. Neurol.
, vol.51
, pp. 433-441
-
-
Papadopoulos, C.M.1
Tsai, S.-Y.2
Aslbiei, T.3
O'Brien, T.E.4
Schwab, M.E.5
Kartje, G.L.6
-
47
-
-
0038721218
-
Immunization with myelin or recombinant Nogo-66/MAG in alum promotes axon regeneration and sprouting after corticospinal tract lesions in the spinal cord
-
Adult mice are immunized with Nogo-66 and MAG and subjected to spinal cord lesioning 3 weeks later. Massive fibre growth, similar to that seen in mice immunized with CNS myelin, is observed from the lesioned corticospinal tract.
-
Sicotte M., Tsatas O., Jeong S.Y., Cai C.-Q., He Z., David S. Immunization with myelin or recombinant Nogo-66/MAG in alum promotes axon regeneration and sprouting after corticospinal tract lesions in the spinal cord. Mol. Cell. Neurosci. 23:2003;251-263 Adult mice are immunized with Nogo-66 and MAG and subjected to spinal cord lesioning 3 weeks later. Massive fibre growth, similar to that seen in mice immunized with CNS myelin, is observed from the lesioned corticospinal tract.
-
(2003)
Mol. Cell. Neurosci.
, vol.23
, pp. 251-263
-
-
Sicotte, M.1
Tsatas, O.2
Jeong, S.Y.3
Cai, C.-Q.4
He, Z.5
David, S.6
-
48
-
-
0038042274
-
Delayed systemic Nogo-66 receptor antagonist promotes recovery from spinal cord injury
-
The Nogo receptor subunit NgR blocking peptide NEP1-40 enhances corticospinal tract regeneration, expression of growth-specific genes, and functional recovery in rats with spinal cord lesions, not only if applied locally at the lesion site, but also if applied subcutaneously and even if applied after a delay of 7 days.
-
Li S., Strittmatter S.M. Delayed systemic Nogo-66 receptor antagonist promotes recovery from spinal cord injury. J. Neurosci. 23:2003;4219-4227 The Nogo receptor subunit NgR blocking peptide NEP1-40 enhances corticospinal tract regeneration, expression of growth-specific genes, and functional recovery in rats with spinal cord lesions, not only if applied locally at the lesion site, but also if applied subcutaneously and even if applied after a delay of 7 days.
-
(2003)
J. Neurosci.
, vol.23
, pp. 4219-4227
-
-
Li, S.1
Strittmatter, S.M.2
-
49
-
-
0033198033
-
Inactivation of Rho signaling pathway promotes CNS axon regeneration
-
Lehmann M., Fournier A., Selles-Navarro I., Dergham P., Sebok A., Lerclerc N., Tigyi G., McKerracher L. Inactivation of Rho signaling pathway promotes CNS axon regeneration. J. Neurosci. 19:1999;7537-7547.
-
(1999)
J. Neurosci.
, vol.19
, pp. 7537-7547
-
-
Lehmann, M.1
Fournier, A.2
Selles-Navarro, I.3
Dergham, P.4
Sebok, A.5
Lerclerc, N.6
Tigyi, G.7
McKerracher, L.8
-
50
-
-
0042171820
-
Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system
-
Dubreuil C.I., Winton M.J., McKerracher L. Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. J. Cell. Biol. 162:2003;233-243.
-
(2003)
J. Cell. Biol.
, vol.162
, pp. 233-243
-
-
Dubreuil, C.I.1
Winton, M.J.2
McKerracher, L.3
-
51
-
-
0037071880
-
Spinal axon regeneration induced by elevation of cyclic AMP
-
Qiu J., Cai D., Dai H., McAtee M., Hoffman P.N., Bregman B.S., Filbin M.T. Spinal axon regeneration induced by elevation of cyclic AMP. Neuron. 34:2002;895-903.
-
(2002)
Neuron
, vol.34
, pp. 895-903
-
-
Qiu, J.1
Cai, D.2
Dai, H.3
McAtee, M.4
Hoffman, P.N.5
Bregman, B.S.6
Filbin, M.T.7
-
52
-
-
0037071890
-
Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation
-
Neumann S., Bradke F., Tessier-Lavigne M., Basbaum A.I. Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation. Neuron. 34:2002;885-893.
-
(2002)
Neuron
, vol.34
, pp. 885-893
-
-
Neumann, S.1
Bradke, F.2
Tessier-Lavigne, M.3
Basbaum, A.I.4
-
53
-
-
0033562391
-
Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor
-
Walsh G.S., Krol K.M., Crutcher K.A., Kawaja M.D. Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor. J. Neurosci. 19:1999;4155-4168.
-
(1999)
J. Neurosci.
, vol.19
, pp. 4155-4168
-
-
Walsh, G.S.1
Krol, K.M.2
Crutcher, K.A.3
Kawaja, M.D.4
-
54
-
-
0037078321
-
Nogo-A expressed in Schwann cells impairs axonal regeneration after peripheral nerve injury
-
•].
-
•].
-
(2002)
J. Cell. Biol.
, vol.159
, pp. 29-35
-
-
Pot, C.1
Simonen, M.2
Weinmann, O.3
Schnell, L.4
Christ, F.5
Stoeckle, S.6
Berger, P.7
Rülicke, T.8
Suter, U.9
Schwab, M.E.10
-
56
-
-
0035319602
-
Plasticity of motor systems after incomplete spinal cord injury
-
Raineteau O., Schwab M.E. Plasticity of motor systems after incomplete spinal cord injury. Nat. Rev. Neurosci. 2:2001;263-274.
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 263-274
-
-
Raineteau, O.1
Schwab, M.E.2
-
57
-
-
0035873174
-
Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A
-
Merkler D., Metz G.A.S., Raineteau O., Dietz V., Schwab M.E., Fouad K. Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A. J. Neurosci. 21:2001;3665-3673.
-
(2001)
J. Neurosci.
, vol.21
, pp. 3665-3673
-
-
Merkler, D.1
Metz, G.A.S.2
Raineteau, O.3
Dietz, V.4
Schwab, M.E.5
Fouad, K.6
-
58
-
-
0030157694
-
Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
-
Basso D.M., Beattie M.S., Bresnahan J.C. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp. Neurol. 139:1996;244-256.
-
(1996)
Exp. Neurol.
, vol.139
, pp. 244-256
-
-
Basso, D.M.1
Beattie, M.S.2
Bresnahan, J.C.3
-
59
-
-
0035856471
-
Cervical sprouting of corticospinal fibers after thoracic spinal cord injury accompanies shifts in evoked motor responses
-
Fouad K., Pedersen V., Schwab M.E., Brösamle C. Cervical sprouting of corticospinal fibers after thoracic spinal cord injury accompanies shifts in evoked motor responses. Curr. Biol. 11:2001;1766-1770.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1766-1770
-
-
Fouad, K.1
Pedersen, V.2
Schwab, M.E.3
Brösamle, C.4
-
60
-
-
0035853114
-
Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury
-
Weidner N., Ner A., Salimi N., Tuszynski M.H. Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury. Proc. Natl. Acad. Sci. U S A. 98:2001;3513-3518.
-
(2001)
Proc. Natl. Acad. Sci. U S a
, vol.98
, pp. 3513-3518
-
-
Weidner, N.1
Ner, A.2
Salimi, N.3
Tuszynski, M.H.4
-
61
-
-
0032082502
-
Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions
-
Thallmair M., Metz G.A.S., Z'Graggen W.J., Raineteau O., Kartje G.L., Schwab M.E. Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions. Nat. Neurosci. 1:1998;124-131.
-
(1998)
Nat. Neurosci.
, vol.1
, pp. 124-131
-
-
Thallmair, M.1
Metz, G.A.S.2
Z'Graggen, W.J.3
Raineteau, O.4
Kartje, G.L.5
Schwab, M.E.6
-
62
-
-
0035810939
-
Functional switch between motor tracts in the presence of the mAb IN-1 in the adult rat
-
Raineteau O., Fouad K., Noth P., Thallmair M., Schwab M.E. Functional switch between motor tracts in the presence of the mAb IN-1 in the adult rat. Proc. Natl. Acad. Sci. U S A. 98:2001;6929-6934.
-
(2001)
Proc. Natl. Acad. Sci. U S a
, vol.98
, pp. 6929-6934
-
-
Raineteau, O.1
Fouad, K.2
Noth, P.3
Thallmair, M.4
Schwab, M.E.5
|