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Volumn 14, Issue 1, 2004, Pages 118-124

Nogo and axon regeneration

Author keywords

Corticospinal tract; CST; MAb; MAG; Monoclonal antibody; Myelin associated glycoprotein; Oligodendrocyte myelin glycoprotein; OMgp; Reticulon; RTN

Indexed keywords

CYCLIC AMP; ISOPROTEIN; NEUTRALIZING ANTIBODY; PEPTIDE; PROTEIN NOGO; PROTEIN P75; PROTEIN SUBUNIT; RECEPTOR; RHO FACTOR;

EID: 1342328010     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.conb.2004.01.004     Document Type: Review
Times cited : (545)

References (62)
  • 1
    • 0029900303 scopus 로고    scopus 로고
    • Degeneration and regeneration of axons in the lesioned spinal cord
    • Schwab M.E., Bartholdi D. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol. Rev. 76:1996;319-370.
    • (1996) Physiol. Rev. , vol.76 , pp. 319-370
    • Schwab, M.E.1    Bartholdi, D.2
  • 2
    • 0037039823 scopus 로고    scopus 로고
    • Repairing the injured spinal cord
    • Schwab M.E. Repairing the injured spinal cord. Science. 295:2002;1029-1031.
    • (2002) Science , vol.295 , pp. 1029-1031
    • Schwab, M.E.1
  • 3
    • 0035893632 scopus 로고    scopus 로고
    • Epidemiology, demographics, and pathophysiology of acute spinal cord injury
    • Sekhon L.H.S., Fehlings M.G. Epidemiology, demographics, and pathophysiology of acute spinal cord injury. Spine. 26:2003;S2-S12.
    • (2003) Spine , vol.26
    • Sekhon, L.H.S.1    Fehlings, M.G.2
  • 4
    • 0019856865 scopus 로고
    • Axonal elongation into peripheral nervous system 'bridges' after central nervous system injury in adult rats
    • David S., Aguayo A.J. Axonal elongation into peripheral nervous system 'bridges' after central nervous system injury in adult rats. Science. 214:1981;931-933.
    • (1981) Science , vol.214 , pp. 931-933
    • David, S.1    Aguayo, A.J.2
  • 5
    • 0021930886 scopus 로고
    • Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors
    • Schwab M.E., Thoenen H. Dissociated neurons regenerate into sciatic but not optic nerve explants in culture irrespective of neurotrophic factors. J. Neurosci. 5:1985;2415-2423.
    • (1985) J. Neurosci. , vol.5 , pp. 2415-2423
    • Schwab, M.E.1    Thoenen, H.2
  • 6
    • 0025017637 scopus 로고
    • Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors
    • Schnell L., Schwab M.E. Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature. 343:1990;269-272.
    • (1990) Nature , vol.343 , pp. 269-272
    • Schnell, L.1    Schwab, M.E.2
  • 7
    • 0034331170 scopus 로고    scopus 로고
    • Regeneration of lesioned corticospinal tract fibers in the adult rat induced by a recombinant, humanized IN-1 antibody fragment
    • Brösamle C., Huber A.B., Fiedler M., Skerra A., Schwab M.E. Regeneration of lesioned corticospinal tract fibers in the adult rat induced by a recombinant, humanized IN-1 antibody fragment. J. Neurosci. 20:2000;8061-8068.
    • (2000) J. Neurosci. , vol.20 , pp. 8061-8068
    • Brösamle, C.1    Huber, A.B.2    Fiedler, M.3    Skerra, A.4    Schwab, M.E.5
  • 8
    • 0033231307 scopus 로고    scopus 로고
    • A therapeutic vaccine approach to stimulate axon regeneration in the adult mammalian spinal cord
    • Huang D.W., McKerracher L., Braun P.E., David S. A therapeutic vaccine approach to stimulate axon regeneration in the adult mammalian spinal cord. Neuron. 24:1999;639-647.
    • (1999) Neuron , vol.24 , pp. 639-647
    • Huang, D.W.1    McKerracher, L.2    Braun, P.E.3    David, S.4
  • 9
    • 0023967246 scopus 로고
    • Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter
    • Caroni P., Schwab M.E. Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter. Neuron. 1:1988;85-96.
    • (1988) Neuron , vol.1 , pp. 85-96
    • Caroni, P.1    Schwab, M.E.2
  • 10
    • 0032563211 scopus 로고    scopus 로고
    • Identification and characterization of a bovine neurite growth inhibitor (bNI-220)
    • Spillmann A.A., Bandtlow C.E., Lottspeich F., Keller F., Schwab M.E. Identification and characterization of a bovine neurite growth inhibitor (bNI-220). J. Biol. Chem. 273:1998;19283-19293.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19283-19293
    • Spillmann, A.A.1    Bandtlow, C.E.2    Lottspeich, F.3    Keller, F.4    Schwab, M.E.5
  • 12
    • 0034719371 scopus 로고    scopus 로고
    • Identification of the Nogo inhibitor of axon regeneration as a reticulon protein
    • Grandpré T., Nakamura F., Vartanian T., Strittmatter S.M. Identification of the Nogo inhibitor of axon regeneration as a reticulon protein. Nature. 403:2000;439-444.
    • (2000) Nature , vol.403 , pp. 439-444
    • Grandpré, T.1    Nakamura, F.2    Vartanian, T.3    Strittmatter, S.M.4
  • 14
    • 0033570319 scopus 로고    scopus 로고
    • Bovine CNS myelin contains neurite growth-inhibitory activity associated with chondroitin sulfate proteoglycan
    • Niederöst B., Zimmermann D.R., Schwab M.E., Bandtlow C.E. Bovine CNS myelin contains neurite growth-inhibitory activity associated with chondroitin sulfate proteoglycan. J. Neurosci. 19:1999;8979-8989.
    • (1999) J. Neurosci. , vol.19 , pp. 8979-8989
    • Niederöst, B.1    Zimmermann, D.R.2    Schwab, M.E.3    Bandtlow, C.E.4
  • 15
    • 0141499228 scopus 로고    scopus 로고
    • Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS
    • Filbin M.T. Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS. Nat. Rev. Neurosci. 4:2003;703-713.
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 703-713
    • Filbin, M.T.1
  • 16
    • 0042858516 scopus 로고    scopus 로고
    • Molecular approaches to spinal cord repair
    • David S., Lacroix S. Molecular approaches to spinal cord repair. Annu. Rev. Neurosci. 26:2003;411-440.
    • (2003) Annu. Rev. Neurosci. , vol.26 , pp. 411-440
    • David, S.1    Lacroix, S.2
  • 18
    • 0036663013 scopus 로고    scopus 로고
    • Localization of Nogo-A and Nogo-66 receptor proteins at sites of axon-myelin and synaptic contact
    • •], this study maps the distribution of Nogo-A in the adult and developing nervous system. In white matter, Nogo-A is localized on the innermost adaxonal and the outermost myelin membranes only. The Nogo receptor NgR is a neuronal protein. Developing neurons also express Nogo-A.
    • •], this study maps the distribution of Nogo-A in the adult and developing nervous system. In white matter, Nogo-A is localized on the innermost adaxonal and the outermost myelin membranes only. The Nogo receptor NgR is a neuronal protein. Developing neurons also express Nogo-A.
    • (2002) J. Neurosci. , vol.22 , pp. 5505-5515
    • Wang, X.1    Chun, S.-J.2    Treloar, H.3    Vartanian, T.4    Greer, C.A.5    Strittmatter, S.M.6
  • 19
    • 0034988117 scopus 로고    scopus 로고
    • Nogo mRNA expression in adult and fetal human and rat nervous tissue and in weight drop injury
    • Josephson A., Widenfalk J., Widmer H.W., Olson L., Spenger C. Nogo mRNA expression in adult and fetal human and rat nervous tissue and in weight drop injury. Exp. Neurol. 169:2001;319-328.
    • (2001) Exp. Neurol. , vol.169 , pp. 319-328
    • Josephson, A.1    Widenfalk, J.2    Widmer, H.W.3    Olson, L.4    Spenger, C.5
  • 21
    • 0038799728 scopus 로고    scopus 로고
    • A reticular rhapsody: Phylogenic evolution and nomenclature of the RTN/Nogo gene family
    • Oertle T., Klinger M., Stuermer C.A.O., Schwab M.E. A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family. FASEB J. 17:2003;1238-1247.
    • (2003) FASEB J. , vol.17 , pp. 1238-1247
    • Oertle, T.1    Klinger, M.2    Stuermer, C.A.O.3    Schwab, M.E.4
  • 22
    • 0038384089 scopus 로고    scopus 로고
    • Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions
    • Nogo-A has at least two active sites for inhibition of neurite growth: a site specific to Nogo-A, and the C-terminal Nogo-66 region that is common to Nogo-A, -B and -C. Both sites are exposed to the extracellular space on the surface of cultured living oligodendrocytes.
    • Oertle T., van der Haar M.E., Bandtlow C.E., Robeva A., Burfeind P., Buss A., Huber A.B., Simonen M., Schnell L., Brösamle C., et al. Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions. J. Neurosci. 23:2003;5393-5406 Nogo-A has at least two active sites for inhibition of neurite growth: a site specific to Nogo-A, and the C-terminal Nogo-66 region that is common to Nogo-A, -B and -C. Both sites are exposed to the extracellular space on the surface of cultured living oligodendrocytes.
    • (2003) J. Neurosci. , vol.23 , pp. 5393-5406
    • Oertle, T.1    Van Der Haar, M.E.2    Bandtlow, C.E.3    Robeva, A.4    Burfeind, P.5    Buss, A.6    Huber, A.B.7    Simonen, M.8    Schnell, L.9    Brösamle, C.10
  • 23
    • 0037198689 scopus 로고    scopus 로고
    • Nogo-66 receptor antagonist peptide promotes axonal regeneration
    • The first 40 amino acids of the C-terminal extracellular loop of Nogo ('Nogo-66') act as an antagonist on the Nogo-66 receptor NgR. In vivo application of this 40-residue peptide in adult rats with partial spinal cord lesions enhances corticospinal tract regeneration, serotonergic-fibre density and locomotor recovery.
    • Grandpré T., Li S., Strittmatter S.M. Nogo-66 receptor antagonist peptide promotes axonal regeneration. Nature. 417:2002;547-551 The first 40 amino acids of the C-terminal extracellular loop of Nogo ('Nogo-66') act as an antagonist on the Nogo-66 receptor NgR. In vivo application of this 40-residue peptide in adult rats with partial spinal cord lesions enhances corticospinal tract regeneration, serotonergic-fibre density and locomotor recovery.
    • (2002) Nature , vol.417 , pp. 547-551
    • Grandpré, T.1    Li, S.2    Strittmatter, S.M.3
  • 24
    • 0035905799 scopus 로고    scopus 로고
    • Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration
    • Fournier A.E., Grandpre T., Strittmatter S.M. Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature. 409:2001;341-346.
    • (2001) Nature , vol.409 , pp. 341-346
    • Fournier, A.E.1    Grandpre, T.2    Strittmatter, S.M.3
  • 27
    • 0344445378 scopus 로고    scopus 로고
    • Signaling mechanisms of the myelin inhibitors of axon regeneration
    • Yiu G., He Z. Signaling mechanisms of the myelin inhibitors of axon regeneration. Curr. Opin. Neurobiol. 13:2003;1-7.
    • (2003) Curr. Opin. Neurobiol. , vol.13 , pp. 1-7
    • Yiu, G.1    He, Z.2
  • 28
    • 0036897583 scopus 로고    scopus 로고
    • A p75 NTR and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein
    • Wong S.T., Henley J.R., Kanning K.C., Huang K., Bothwell M., Poo M.-M. A p75 NTR and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein. Nat. Neurosci. 5:2002;1302-1308.
    • (2002) Nat. Neurosci. , vol.5 , pp. 1302-1308
    • Wong, S.T.1    Henley, J.R.2    Kanning, K.C.3    Huang, K.4    Bothwell, M.5    Poo, M.-M.6
  • 29
    • 0027514515 scopus 로고
    • Role of intracellular calcium in NI-35-evoked collapse of neuronal growth cones
    • Bandtlow C.E., Schmidt M.F., Hassinger T.D., Schwab M.E., Kater S.B. Role of intracellular calcium in NI-35-evoked collapse of neuronal growth cones. Science. 259:1993;80-83.
    • (1993) Science , vol.259 , pp. 80-83
    • Bandtlow, C.E.1    Schmidt, M.F.2    Hassinger, T.D.3    Schwab, M.E.4    Kater, S.B.5
  • 30
    • 0036895744 scopus 로고    scopus 로고
    • Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1
    • Niederöst B., Oertle T., Fritsche J., Mckinney R.A., Bandtlow C.E. Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1. J Neurosci. 22:2002;10368-10376.
    • (2002) J Neurosci , vol.22 , pp. 10368-10376
    • Niederöst, B.1    Oertle, T.2    Fritsche, J.3    McKinney, R.A.4    Bandtlow, C.E.5
  • 31
    • 0037443069 scopus 로고    scopus 로고
    • Rho kinase inhibition enhances axonal regeneration in the injured CNS
    • Fournier A.E., Takizawa B.T., Strittmatter S.M. Rho kinase inhibition enhances axonal regeneration in the injured CNS. J. Neurosci. 23:2003;1416-1423.
    • (2003) J. Neurosci. , vol.23 , pp. 1416-1423
    • Fournier, A.E.1    Takizawa, B.T.2    Strittmatter, S.M.3
  • 32
    • 0036878139 scopus 로고    scopus 로고
    • An engineered IN-1 Fab fragment with improved affinity for the Nogo-A axonal growth inhibitor permits immunochemical detection and shows enhanced neutralizing acitivty
    • Fiedler M., Horn C., Bandtlow C., Schwab M.E., Skerra A. An engineered IN-1 Fab fragment with improved affinity for the Nogo-A axonal growth inhibitor permits immunochemical detection and shows enhanced neutralizing acitivty. Protein Eng. 15:2002;931-941.
    • (2002) Protein Eng. , vol.15 , pp. 931-941
    • Fiedler, M.1    Horn, C.2    Bandtlow, C.3    Schwab, M.E.4    Skerra, A.5
  • 36
    • 0037109760 scopus 로고    scopus 로고
    • Truncated soluble Nogo receptor binds Nogo-66 and blocks inhibition of axon growth by myelin
    • Fournier A.E., Gould G.C., Liu B.P., Strittmatter S.M. Truncated soluble Nogo receptor binds Nogo-66 and blocks inhibition of axon growth by myelin. J. Neurosci. 22:2002;8876-8883.
    • (2002) J. Neurosci. , vol.22 , pp. 8876-8883
    • Fournier, A.E.1    Gould, G.C.2    Liu, B.P.3    Strittmatter, S.M.4
  • 39
    • 0037104645 scopus 로고    scopus 로고
    • Arginase I and Polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth on MAG and myelin in vitro
    • Cai D., Deng K., Mellado W., Lee J., Ratan R.R., Filbin M.T. Arginase I and Polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth on MAG and myelin in vitro. Neuron. 35:2002;711-719.
    • (2002) Neuron , vol.35 , pp. 711-719
    • Cai, D.1    Deng, K.2    Mellado, W.3    Lee, J.4    Ratan, R.R.5    Filbin, M.T.6
  • 40
    • 0034654086 scopus 로고    scopus 로고
    • Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured Purkinje cell axons
    • Buffo A., Zagrebelsky M., Huber A.B., Skerra A., Schwab M.E., Strata P., Rossi F. Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured Purkinje cell axons. J. Neurosci. 20:2000;2275-2286.
    • (2000) J. Neurosci. , vol.20 , pp. 2275-2286
    • Buffo, A.1    Zagrebelsky, M.2    Huber, A.B.3    Skerra, A.4    Schwab, M.E.5    Strata, P.6    Rossi, F.7
  • 41
    • 0037316286 scopus 로고    scopus 로고
    • Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats
    • Wiessner C., Bareyre F.M., Allegrini P.R., Mir A.K., Frentzel S., Zurini M., Schnell L., Oertle T., Schwab M.E. Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats. J. Cereb. Blood Flow Metab. 23:2003;154-165.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 154-165
    • Wiessner, C.1    Bareyre, F.M.2    Allegrini, P.R.3    Mir, A.K.4    Frentzel, S.5    Zurini, M.6    Schnell, L.7    Oertle, T.8    Schwab, M.E.9
  • 43
    • 0032189056 scopus 로고    scopus 로고
    • Retrograde regulation of growth-associated gene expression in adult rat Purkinje cells by myelin-associated neurite growth inhibitory proteins
    • Zagrebelsky M., Buffo A., Skerra A., Schwab M.E., Strata P., Rossi F. Retrograde regulation of growth-associated gene expression in adult rat Purkinje cells by myelin-associated neurite growth inhibitory proteins. J. Neurosci. 18:1998;7912-7929.
    • (1998) J. Neurosci. , vol.18 , pp. 7912-7929
    • Zagrebelsky, M.1    Buffo, A.2    Skerra, A.3    Schwab, M.E.4    Strata, P.5    Rossi, F.6
  • 44
    • 0037104719 scopus 로고    scopus 로고
    • Long-lasting sprouting and gene expression changes induced by the monoclonal antibody IN-1 in the adult spinal cord
    • Bareyre F.M., Haudenschild B., Schwab M.E. Long-lasting sprouting and gene expression changes induced by the monoclonal antibody IN-1 in the adult spinal cord. J. Neurosci. 22:2002;7097-7110.
    • (2002) J. Neurosci. , vol.22 , pp. 7097-7110
    • Bareyre, F.M.1    Haudenschild, B.2    Schwab, M.E.3
  • 45
    • 0028867947 scopus 로고
    • Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors
    • Bregman B.S., Kunkel-Bagden E., Schnell L., Dai H.N., Gao D., Schwab M.E. Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature. 378:1995;498-501.
    • (1995) Nature , vol.378 , pp. 498-501
    • Bregman, B.S.1    Kunkel-Bagden, E.2    Schnell, L.3    Dai, H.N.4    Gao, D.5    Schwab, M.E.6
  • 46
    • 0036196245 scopus 로고    scopus 로고
    • Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN-1 antibody treatment in the adult rat
    • Papadopoulos C.M., Tsai S.-Y., Aslbiei T., O'Brien T.E., Schwab M.E., Kartje G.L. Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN-1 antibody treatment in the adult rat. Ann. Neurol. 51:2002;433-441.
    • (2002) Ann. Neurol. , vol.51 , pp. 433-441
    • Papadopoulos, C.M.1    Tsai, S.-Y.2    Aslbiei, T.3    O'Brien, T.E.4    Schwab, M.E.5    Kartje, G.L.6
  • 47
    • 0038721218 scopus 로고    scopus 로고
    • Immunization with myelin or recombinant Nogo-66/MAG in alum promotes axon regeneration and sprouting after corticospinal tract lesions in the spinal cord
    • Adult mice are immunized with Nogo-66 and MAG and subjected to spinal cord lesioning 3 weeks later. Massive fibre growth, similar to that seen in mice immunized with CNS myelin, is observed from the lesioned corticospinal tract.
    • Sicotte M., Tsatas O., Jeong S.Y., Cai C.-Q., He Z., David S. Immunization with myelin or recombinant Nogo-66/MAG in alum promotes axon regeneration and sprouting after corticospinal tract lesions in the spinal cord. Mol. Cell. Neurosci. 23:2003;251-263 Adult mice are immunized with Nogo-66 and MAG and subjected to spinal cord lesioning 3 weeks later. Massive fibre growth, similar to that seen in mice immunized with CNS myelin, is observed from the lesioned corticospinal tract.
    • (2003) Mol. Cell. Neurosci. , vol.23 , pp. 251-263
    • Sicotte, M.1    Tsatas, O.2    Jeong, S.Y.3    Cai, C.-Q.4    He, Z.5    David, S.6
  • 48
    • 0038042274 scopus 로고    scopus 로고
    • Delayed systemic Nogo-66 receptor antagonist promotes recovery from spinal cord injury
    • The Nogo receptor subunit NgR blocking peptide NEP1-40 enhances corticospinal tract regeneration, expression of growth-specific genes, and functional recovery in rats with spinal cord lesions, not only if applied locally at the lesion site, but also if applied subcutaneously and even if applied after a delay of 7 days.
    • Li S., Strittmatter S.M. Delayed systemic Nogo-66 receptor antagonist promotes recovery from spinal cord injury. J. Neurosci. 23:2003;4219-4227 The Nogo receptor subunit NgR blocking peptide NEP1-40 enhances corticospinal tract regeneration, expression of growth-specific genes, and functional recovery in rats with spinal cord lesions, not only if applied locally at the lesion site, but also if applied subcutaneously and even if applied after a delay of 7 days.
    • (2003) J. Neurosci. , vol.23 , pp. 4219-4227
    • Li, S.1    Strittmatter, S.M.2
  • 50
    • 0042171820 scopus 로고    scopus 로고
    • Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system
    • Dubreuil C.I., Winton M.J., McKerracher L. Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. J. Cell. Biol. 162:2003;233-243.
    • (2003) J. Cell. Biol. , vol.162 , pp. 233-243
    • Dubreuil, C.I.1    Winton, M.J.2    McKerracher, L.3
  • 52
    • 0037071890 scopus 로고    scopus 로고
    • Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation
    • Neumann S., Bradke F., Tessier-Lavigne M., Basbaum A.I. Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation. Neuron. 34:2002;885-893.
    • (2002) Neuron , vol.34 , pp. 885-893
    • Neumann, S.1    Bradke, F.2    Tessier-Lavigne, M.3    Basbaum, A.I.4
  • 53
    • 0033562391 scopus 로고    scopus 로고
    • Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor
    • Walsh G.S., Krol K.M., Crutcher K.A., Kawaja M.D. Enhanced neurotrophin-induced axon growth in myelinated portions of the CNS in mice lacking the p75 neurotrophin receptor. J. Neurosci. 19:1999;4155-4168.
    • (1999) J. Neurosci. , vol.19 , pp. 4155-4168
    • Walsh, G.S.1    Krol, K.M.2    Crutcher, K.A.3    Kawaja, M.D.4
  • 56
    • 0035319602 scopus 로고    scopus 로고
    • Plasticity of motor systems after incomplete spinal cord injury
    • Raineteau O., Schwab M.E. Plasticity of motor systems after incomplete spinal cord injury. Nat. Rev. Neurosci. 2:2001;263-274.
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 263-274
    • Raineteau, O.1    Schwab, M.E.2
  • 57
    • 0035873174 scopus 로고    scopus 로고
    • Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A
    • Merkler D., Metz G.A.S., Raineteau O., Dietz V., Schwab M.E., Fouad K. Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A. J. Neurosci. 21:2001;3665-3673.
    • (2001) J. Neurosci. , vol.21 , pp. 3665-3673
    • Merkler, D.1    Metz, G.A.S.2    Raineteau, O.3    Dietz, V.4    Schwab, M.E.5    Fouad, K.6
  • 58
    • 0030157694 scopus 로고    scopus 로고
    • Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
    • Basso D.M., Beattie M.S., Bresnahan J.C. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp. Neurol. 139:1996;244-256.
    • (1996) Exp. Neurol. , vol.139 , pp. 244-256
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 59
    • 0035856471 scopus 로고    scopus 로고
    • Cervical sprouting of corticospinal fibers after thoracic spinal cord injury accompanies shifts in evoked motor responses
    • Fouad K., Pedersen V., Schwab M.E., Brösamle C. Cervical sprouting of corticospinal fibers after thoracic spinal cord injury accompanies shifts in evoked motor responses. Curr. Biol. 11:2001;1766-1770.
    • (2001) Curr. Biol. , vol.11 , pp. 1766-1770
    • Fouad, K.1    Pedersen, V.2    Schwab, M.E.3    Brösamle, C.4
  • 60
    • 0035853114 scopus 로고    scopus 로고
    • Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury
    • Weidner N., Ner A., Salimi N., Tuszynski M.H. Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury. Proc. Natl. Acad. Sci. U S A. 98:2001;3513-3518.
    • (2001) Proc. Natl. Acad. Sci. U S a , vol.98 , pp. 3513-3518
    • Weidner, N.1    Ner, A.2    Salimi, N.3    Tuszynski, M.H.4
  • 61
    • 0032082502 scopus 로고    scopus 로고
    • Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions
    • Thallmair M., Metz G.A.S., Z'Graggen W.J., Raineteau O., Kartje G.L., Schwab M.E. Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions. Nat. Neurosci. 1:1998;124-131.
    • (1998) Nat. Neurosci. , vol.1 , pp. 124-131
    • Thallmair, M.1    Metz, G.A.S.2    Z'Graggen, W.J.3    Raineteau, O.4    Kartje, G.L.5    Schwab, M.E.6
  • 62


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