Effects of reduced endogenous 5-HT on the in vivo binding of the serotonin transporter radioligand 11C-DASB in healthy humans

Synapse

Volumn 55, Issue 3, 2005, Pages 164-175

  Talbot, Peter S ^a,b   Frankle, W Gordon ^a   Hwang, Dah Ren ^a   Huang, Yiyun ^a   Suckow, Raymond F ^b   Slifstein, Mark ^a   Abi Dargham, Anissa ^a   Laruelle, Marc ^a  

^a New York State Psychiatric Institute ^*  (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

11C DASB; Positron emission tomography; Rapid tryptophan depletion

Indexed keywords

3 AMINO 4 [2 [(DIMETHYLAMINO)METHYL]PHENYLTHIO)BENZONITRILE C 11; RADIOLIGAND; SEROTONIN; SEROTONIN TRANSPORTER; TRACER; TRYPTOPHAN; UNCLASSIFIED DRUG;

ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DISTRIBUTION VOLUME; FEMALE; GENE DELETION; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; KINETICS; MALE; NAUSEA; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN BINDING; VOMITING;

ADULT; AMINO ACIDS, NEUTRAL; BENZYLAMINES; BINDING, COMPETITIVE; BRAIN; BRAIN MAPPING; CARBON RADIOISOTOPES; DOWN-REGULATION; FEMALE; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; PHARMACOKINETICS; POSITRON-EMISSION TOMOGRAPHY; REFERENCE VALUES; REGIONAL BLOOD FLOW; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SYNAPTIC TRANSMISSION; TRYPTOPHAN;

EID: 13244299240     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.20105     Document Type: Article

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