In vivo binding properties of [Carbonyl-11C]WAY-100635: Effect of endogenous serotonin

Synapse

Volumn 40, Issue 2, 2001, Pages 122-129

  De Vries, Bert B A ^a   Tyson, Jess ^b   Winter, Robin M ^a   Malcolm, Sue ^a,c  

^a GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

5 HT1A receptor; carbonyl 11C WAY 100635; Endogenous serotonin; In vivo binding

Indexed keywords

5,7 DIHYDROXYTRYPTAMINE; CARBON 11; CARBONYL DERIVATIVE; FENFLURAMINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; RESERPINE; SEROTONIN; SEROTONIN 1A RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DENERVATION; FRONTAL CORTEX; HIPPOCAMPUS; LIGAND BINDING; MALE; MICRODIALYSIS; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAPHE NUCLEUS; RAT; RECEPTOR BINDING; SEROTONIN RELEASE; SEROTONINERGIC NERVE CELL; TISSUE DISTRIBUTION;

5,7-DIHYDROXYTRYPTAMINE; ANIMALS; BINDING SITES; BRAIN; CARBON RADIOISOTOPES; HIPPOCAMPUS; MALE; NEURONS; NEUROTOXINS; PIPERAZINES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN; SEROTONIN AGENTS; SEROTONIN ANTAGONISTS;

EID: 0035080412     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.1033     Document Type: Article

References (34)

1. 11C]NNC 756
2. 1A receptor in primate brain neurons and glial cells
3. 1-like dopamine receptor ligand binding during altered endogenous dopamine levels in the primate brain
4. 3H]spiperone binding: Evidence for accumulation in corpus striatum by agonist-mediated receptor internalization
5. 11C-raclopride is altered by drugs that modify synaptic dopamine levels
6. Assessment of dynamic neurotransmitter changes with bolus or infusion delivery of neuroreceptor ligands
7. 11C]raclopride binding to D2-dopamine receptors studied by PET - A comparison to the equilibrium analysis
8. The advantage of using positron emission tomography in drug research
9. 1A receptors in the primate brain
10. Quantitative analyses of carbonyl-carbon-11-WAY-100635 binding to central 5-hydroxytryptamine-1A receptors in man
11. 2-dopamine receptors in the monkey brain
12. 1A receptors in rat brain membranes
13. 11C]WAY-100635
14. 2 receptor binding in patients with chronic schizophrenia
15. Depletion and repletion of cortical tissue and dialysate 5-HT after reserpine
16. Quantitation of carbon-11-labeled raclopride in rat striatum using positron emission tomography
17. 3H]raclopride in reserpine-treated mouse brain
18. 11C]WAY-100635: PET with anatomic standardization technique
19. 1A receptor antagonist
20. 1A receptor antagonist, to rat brain
21. Effect of D-fenfluramine on serotonin release in brains of anaesthetized rats
22. Imaging synaptic neurotransmission with in vivo binding competition techniques: A critical review
23. 2 receptor occupancy by endogenous dopamine in humans
24. Sub-types of serotonin receptors: Biochemical changes and pharmacological consequences
25. 11C-carboxylation of an immobilized Grignard reagent
26. 1A receptor mRNA in the rat brain
27. 11C]WAY-100635 - Explanation of high signal contrast in PET and an aid to biomathematical modelling
28. 11C]WAY-100635
29. Serotonin receptors: Subtypes, functional responses and therapeutic relevance
30. 3-receptor agonist (+/-)-7-hydroxy-N,N-di-n-propyl-2-aminotetralin (7-OH-DPAT) attenuates morphine-induced hyperlocomotion in mice
31. 11C]raclopride?: PET studies combined with microdialysis in conscious monkeys
32. 1 receptor subtypes in the brain of control or 5,7-dihydroxytryptamine-treated rats
33. 1A receptors to astroglial cells in adult rats: Implications for neuronal-glial interactions and psychoactive drug mechanism of action