A reduced extracellular serotonin level increases the 5-HT1A PET ligand 18F-MPPF binding in the rat hippocampus

Journal of Nuclear Medicine

Volumn 44, Issue 9, 2003, Pages 1495-1501

  Zimmer, Luc ^a,b   Rbah, Latifa ^a   Giacomelli, Fabrice ^c   Le Bars, Didier ^a   Renaud, Bernard ^b  

^a Biomedical Cyclotron   (France)

^b UNIVERSITÉ LYON 1   (France)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

microprobe; 4,2 (methoxyphenyl) 1 2 (N 2 pyridinyl) p fluorobenzamido ethylpiperazine; Microdialysis; p ethynylphenylalanine; Serotonin; Serotonin receptors

Indexed keywords

4,2' METHOXYPHENYL 1 [2' (N 2'' PYRIDINYL) 4 FLUOROBENZAMIDO] ETHYLPIPERAZINE; ENZYME INHIBITOR; FLUORINE 18; LIGAND; NEUROTRANSMITTER; PHENYLALANINE DERIVATIVE; PIPERAZINE DERIVATIVE; SEROTONIN; SEROTONIN 1A RECEPTOR; TRYPTOPHAN HYDROXYLASE; UNCLASSIFIED DRUG; 4 (2' METHOXYPHENYL) 1 (2' (N 2' PYRIDINYL) P (18F)FLUOROBENZAMIDO )ETHYLPIPERAZINE; 4-(2'-METHOXYPHENYL)-1-(2'-(N-2'-PYRIDINYL)-P-(18F)FLUOROBENZAMIDO )ETHYLPIPERAZINE; ALANINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; P ETHYNYLPHENYLALANINE; P-ETHYNYLPHENYLALANINE; PYRIDINE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; SEROTONIN 1 RECEPTOR; SEROTONIN RECEPTOR;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BRAIN RADIOGRAPHY; BRAIN TISSUE; CEREBELLUM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIALYSATE; EXTRACELLULAR SPACE; HIPPOCAMPUS; MICRODIALYSIS; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION; ANIMAL; COMPARATIVE STUDY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG EFFECT; MALE; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; PROTEIN BINDING; REFERENCE VALUE; SCINTISCANNING; SPRAGUE DAWLEY RAT;

ALANINE; ANIMALS; CEREBELLUM; EXTRACELLULAR SPACE; HIPPOCAMPUS; LIGANDS; MALE; METABOLIC CLEARANCE RATE; PIPERAZINES; PROTEIN BINDING; PYRIDINES; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; REFERENCE VALUES; SEROTONIN; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0142150251     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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