Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 Å reveals novel features of cytochrome P450

Journal of Biological Chemistry

Volumn 278, Issue 7, 2003, Pages 5141-5147

  Leys, David ^a   Mowat, Christopher G ^b   McLean, Kirsty J ^a   Richmond, Alison ^c   Chapman, Stephen K ^b   Walkinshaw, Malcolm D ^b   Munro, Andrew W ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CARRIER CONCENTRATION; CONFORMATIONS; CRYSTAL ATOMIC STRUCTURE; PROTONS;

ATOMIC RESOLUTION;

BIOCHEMISTRY;

ARGININE; BACTERIAL ENZYME; CYSTEINE; CYTOCHROME P450; CYTOCHROME P450 107A1; CYTOCHROME P450 121; CYTOCHROME P450 2C5; HEME; IRON; PROLINE; SERINE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CYTOCHROME P 450 CYP121; CYTOCHROME P-450 CYP121; OXYGEN;

ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ELECTRON; ENZYME ACTIVE SITE; ENZYME STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTON TRANSPORT; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; METABOLISM; PROTEIN BINDING;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); MAMMALIA; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

BACTERIAL PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; OXYGEN; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 0038136970     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209928200     Document Type: Article

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