Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: Evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degradation factor-1], AUF-2, tristetraprolin, HuR (Hu antigen R) or FBP1 (far-upstream-sequence-element-binding protein 1)

Biochemical Journal

Volumn 377, Issue 3, 2004, Pages 629-639

  Sully, Gareth ^a   Dean, Jonathan L E ^a   Wait, Robin ^a   Rawlinson, Lesley ^a   Santalucia, Tomas ^a   Saklatvala, Jeremy ^a   Clark, Andrew R ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

AU rich element (ARE); Cyclo oxygenase 2; Mitogen activated protein kinase p38; mRNA stability; Post transcriptional regulation

Indexed keywords

ANTIGENS; BIODEGRADATION; CELLS; ENZYMES; RNA;

FUNCTIONAL DISSECTION;

BIOCHEMISTRY;

AU RICH ELEMENT POLY(U) BINDING DEGRADATION FACTOR 2; BETA GLOBULIN; CYCLOOXYGENASE 2; FAR UPSTREAM SEQUENCE ELEMENT BINDING PROTEIN 1; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; HU ANTIGEN R; MESSENGER RNA; MUTANT PROTEIN; RNA BINDING PROTEIN; TRISTETRAPOLIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING ASSAY; CONTROLLED STUDY; GENE SEQUENCE; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN RNA BINDING; PROTEIN STRUCTURE; REGULATORY MECHANISM; REPORTER GENE; RNA INTERFERENCE; RNA STABILITY;

EID: 1242337338     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj20031484     Document Type: Article

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