메뉴 건너뛰기




Volumn 67, Issue 5, 2000, Pages 512-520

Enzyme induction in the elderly: Effect of rifampin on the pharmacokinetics and pharmacodynamics of propafenone

Author keywords

[No Author keywords available]

Indexed keywords

PROPAFENONE; RIFAMPICIN;

EID: 0034035056     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1067/mcp.2000.106872     Document Type: Article
Times cited : (66)

References (37)
  • 1
    • 0020426927 scopus 로고
    • Drug interactions and the elderly
    • 1. Reidenberg MM. Drug interactions and the elderly. J Am Geriatr Soc 1982;30:S67-8.
    • (1982) J Am Geriatr Soc , vol.30
    • Reidenberg, M.M.1
  • 2
    • 0029337643 scopus 로고
    • Pharmacokinetic optimisation of drug therapy in elderly patients
    • 2. Parker BM, Cusack BJ, Vestal RE. Pharmacokinetic optimisation of drug therapy in elderly patients. Drugs Aging 1995;7:10-8.
    • (1995) Drugs Aging , vol.7 , pp. 10-18
    • Parker, B.M.1    Cusack, B.J.2    Vestal, R.E.3
  • 3
    • 0031746034 scopus 로고    scopus 로고
    • Important drug-drug interactions in the elderly
    • 3. Seymour RM, Routledge PA. Important drug-drug interactions in the elderly. Drugs Aging 1998;12:485-94.
    • (1998) Drugs Aging , vol.12 , pp. 485-494
    • Seymour, R.M.1    Routledge, P.A.2
  • 7
    • 0030982413 scopus 로고    scopus 로고
    • Clinical pharmacokinetic considerations in the elderly
    • 7. Kinirons MT, Crome P. Clinical pharmacokinetic considerations in the elderly. Clin Pharmacokinet 1997;33:302-12.
    • (1997) Clin Pharmacokinet , vol.33 , pp. 302-312
    • Kinirons, M.T.1    Crome, P.2
  • 8
    • 0031727173 scopus 로고    scopus 로고
    • Drug dosage in the elderly: Is it rational?
    • 8. Turnheim K. Drug dosage in the elderly: is it rational? Drugs Aging 1998;13:357-79.
    • (1998) Drugs Aging , vol.13 , pp. 357-379
    • Turnheim, K.1
  • 10
    • 0026708362 scopus 로고
    • Effect of age and gender on the activity of human hepatic CYP3A
    • 10. Hunt CM, Westerkam WR, Stave GM. Effect of age and gender on the activity of human hepatic CYP3A. Biochem Pharmacol 1992;44:275-83.
    • (1992) Biochem Pharmacol , vol.44 , pp. 275-283
    • Hunt, C.M.1    Westerkam, W.R.2    Stave, G.M.3
  • 11
    • 0029128788 scopus 로고
    • Age but not gender selectively affects expression of individual cytochrome P450 proteins in human liver
    • 11. George J, Byth K, Farrell GC. Age but not gender selectively affects expression of individual cytochrome P450 proteins in human liver. Biochem Pharmacol 1995;50: 727-30.
    • (1995) Biochem Pharmacol , vol.50 , pp. 727-730
    • George, J.1    Byth, K.2    Farrell, G.C.3
  • 12
    • 0030973784 scopus 로고    scopus 로고
    • Age and cytochrome P450-linked drug metabolism in humans: An analysis of 226 subjects with equal histopathologic conditions
    • 12. Sotaniemi EA, Arranto AJ, Pelkonen O, Fasanen M. Age and cytochrome P450-linked drug metabolism in humans: an analysis of 226 subjects with equal histopathologic conditions. Clin Pharmacol Ther 1997;61:331-9.
    • (1997) Clin Pharmacol Ther , vol.61 , pp. 331-339
    • Sotaniemi, E.A.1    Arranto, A.J.2    Pelkonen, O.3    Fasanen, M.4
  • 13
    • 0024398368 scopus 로고
    • Implications of altered drug disposition in the elderly: Studies of benzodiazepines
    • 13. Greenblatt DJ, Shader RI, Harmatz JS. Implications of altered drug disposition in the elderly: studies of benzodiazepines. J Clin Pharmacol 1989;29:866-72.
    • (1989) J Clin Pharmacol , vol.29 , pp. 866-872
    • Greenblatt, D.J.1    Shader, R.I.2    Harmatz, J.S.3
  • 14
    • 0025885499 scopus 로고
    • The effect of age on glucuronidation and sulphation of paracetamol in human liver fractions
    • 14. Herd B, Wynne H, Wright P, James O, Woodhouse K. The effect of age on glucuronidation and sulphation of paracetamol in human liver fractions. Br J Clin Pharmacol 1991;32:768-70.
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 768-770
    • Herd, B.1    Wynne, H.2    Wright, P.3    James, O.4    Woodhouse, K.5
  • 16
    • 0026737244 scopus 로고
    • Glucuronidation of drugs: A reevaluation of the pharmacological significance of the conjugates and modulating factors
    • 16. Kroemer HK, Klotz U. Glucuronidation of drugs: a reevaluation of the pharmacological significance of the conjugates and modulating factors. Clin Pharmacokinet 1992;23:292-310.
    • (1992) Clin Pharmacokinet , vol.23 , pp. 292-310
    • Kroemer, H.K.1    Klotz, U.2
  • 17
    • 0031794361 scopus 로고    scopus 로고
    • Inhibition and induction of cytochrome P450 and the clinical implications
    • 17. Lin JH, Lu AYH. Inhibition and induction of cytochrome P450 and the clinical implications. Clin Pharmacokinet 1998;35:361-90.
    • (1998) Clin Pharmacokinet , vol.35 , pp. 361-390
    • Lin, J.H.1    Lu, A.Y.H.2
  • 18
    • 8544224973 scopus 로고    scopus 로고
    • The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence
    • 18. Mackenzie PI, Owens IS, Burchell B, Bock KW, Bairoch A, Belanger A, et al. The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics 1997;7: 255-69.
    • (1997) Pharmacogenetics , vol.7 , pp. 255-269
    • Mackenzie, P.I.1    Owens, I.S.2    Burchell, B.3    Bock, K.W.4    Bairoch, A.5    Belanger, A.6
  • 19
    • 0024548251 scopus 로고
    • In vitro characterization of the human cytochrome P-450 involved in polymorphic oxidation of propafenone
    • 19. Kroemer HK, Mikus G, Kronbach T, Meyer UA, Eichelbaum M. In vitro characterization of the human cytochrome P-450 involved in polymorphic oxidation of propafenone. Clin Pharmacol Ther 1989;45:28-33.
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 28-33
    • Kroemer, H.K.1    Mikus, G.2    Kronbach, T.3    Meyer, U.A.4    Eichelbaum, M.5
  • 20
    • 0027460033 scopus 로고
    • Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: Molecular base for interaction potential and variable disposition of active metabolites
    • 20. Botsch S, Gautier JC, Beaune P, Eichelbaum M, Kroemer HK. Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites. Mol Pharmacol 1993;43:120-6.
    • (1993) Mol Pharmacol , vol.43 , pp. 120-126
    • Botsch, S.1    Gautier, J.C.2    Beaune, P.3    Eichelbaum, M.4    Kroemer, H.K.5
  • 21
    • 0021738731 scopus 로고
    • Clinical pharmacology of propafenone: Pharmacokinetics, metabolism and concentration-response relations
    • 21. Siddoway LA, Roden DM, Woosley RL. Clinical pharmacology of propafenone: pharmacokinetics, metabolism and concentration-response relations. Am J Cardiol 1984; 54:9D-12D.
    • (1984) Am J Cardiol , vol.54
    • Siddoway, L.A.1    Roden, D.M.2    Woosley, R.L.3
  • 22
    • 0031884233 scopus 로고    scopus 로고
    • Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population
    • 22. Griese EU, Zanger UM, Brudermanns U, Gaedigk A, Mikus G, Moerike K, et al. Assessment of the predictive power of genotypes for the in-vivo catalytic function of CYP2D6 in a German population. Pharmacogenetics 1998;8:15-26.
    • (1998) Pharmacogenetics , vol.8 , pp. 15-26
    • Griese, E.U.1    Zanger, U.M.2    Brudermanns, U.3    Gaedigk, A.4    Mikus, G.5    Moerike, K.6
  • 23
    • 0032738791 scopus 로고    scopus 로고
    • Consequences of rifampicin treatment on propafenone disposition in extensive and poor metabolisers of CYP2D6
    • 23. Dilger K, Greiner B, Fromm MF, Hofmann U, Kroemer HK, Eichelbaum M. Consequences of rifampicin treatment on propafenone disposition in extensive and poor metabolisers of CYP2D6. Pharmacogenetics 1999;9:551-9.
    • (1999) Pharmacogenetics , vol.9 , pp. 551-559
    • Dilger, K.1    Greiner, B.2    Fromm, M.F.3    Hofmann, U.4    Kroemer, H.K.5    Eichelbaum, M.6
  • 26
    • 0020620239 scopus 로고
    • Investigations on the pharmacokinetics of propafenone in man
    • 26. Hollmann M, Brode E, Hotz D, Kaumeier S, Kehrhan OH. Investigations on the pharmacokinetics of propafenone in man. Drug Res 1983:33:763-70.
    • (1983) Drug Res , vol.33 , pp. 763-770
    • Hollmann, M.1    Brode, E.2    Hotz, D.3    Kaumeier, S.4    Kehrhan, O.H.5
  • 29
    • 0031941137 scopus 로고    scopus 로고
    • Gut wall metabolism of verapamil in older people: Effects of rifampicin-mediated enzyme induction
    • 29. Fromm MF, Dilger K, Busse D, Kroemer HK, Eichelbaum M, Klotz U. Gut wall metabolism of verapamil in older people: effects of rifampicin-mediated enzyme induction. Br J Clin Pharmacol 1998;48:247-55.
    • (1998) Br J Clin Pharmacol , vol.48 , pp. 247-255
    • Fromm, M.F.1    Dilger, K.2    Busse, D.3    Kroemer, H.K.4    Eichelbaum, M.5    Klotz, U.6
  • 30
    • 0030959379 scopus 로고    scopus 로고
    • Pharmacogenetic determinants of codeine induction by rifampin: The impact on codeine's respiratory, psychomotor and miotic effects
    • 30. Caraco Y, Sheller J, Wood AJJ. Pharmacogenetic determinants of codeine induction by rifampin: the impact on codeine's respiratory, psychomotor and miotic effects. J Pharmacol Exp Ther 1997;281:330-6.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 330-336
    • Caraco, Y.1    Sheller, J.2    Wood, A.J.J.3
  • 31
    • 0023112104 scopus 로고
    • Paracetamol as a test drug to determine glucuronide formation in man. Effects of inducers and of smoking
    • 31. Bock KW, Wiltfang J, Blume R, Ullrich D, Bircher J. Paracetamol as a test drug to determine glucuronide formation in man. Effects of inducers and of smoking. Eur J Clin Pharmacol 1987;31:677-83.
    • (1987) Eur J Clin Pharmacol , vol.31 , pp. 677-683
    • Bock, K.W.1    Wiltfang, J.2    Blume, R.3    Ullrich, D.4    Bircher, J.5
  • 32
    • 0030059953 scopus 로고    scopus 로고
    • Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells
    • 32. Schuetz EG, Beck WT, Schuetz JD. Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Mol Pharmacol 1996;49:311-8.
    • (1996) Mol Pharmacol , vol.49 , pp. 311-318
    • Schuetz, E.G.1    Beck, W.T.2    Schuetz, J.D.3
  • 33
    • 0029898576 scopus 로고    scopus 로고
    • Structural requirements for activity of propafenone-type modulators in P-glycoprotein-mediated multidrug resistance
    • 33. Chiba P, Ecker G, Schmid D, Drach J, Tell B, Goldenberg S, et al. Structural requirements for activity of propafenone-type modulators in P-glycoprotein-mediated multidrug resistance. Mol Pharmacol 1996;49:1122-30.
    • (1996) Mol Pharmacol , vol.49 , pp. 1122-1130
    • Chiba, P.1    Ecker, G.2    Schmid, D.3    Drach, J.4    Tell, B.5    Goldenberg, S.6
  • 34
    • 0025005022 scopus 로고
    • Induction of polymorphic 4′-hydroxylation of S-mephenytoin by rifampicin
    • 34. Zhou HH, Anthony LB, Wood JJ, Wilkinson GR. Induction of polymorphic 4′-hydroxylation of S-mephenytoin by rifampicin. Br J Clin Pharmacol 1990;30:471-5.
    • (1990) Br J Clin Pharmacol , vol.30 , pp. 471-475
    • Zhou, H.H.1    Anthony, L.B.2    Wood, J.J.3    Wilkinson, G.R.4
  • 35
    • 0028240671 scopus 로고
    • Accelerated caffeine metabolism after omeprazole treatment is indicated by urinary metabolite ratios: Coincidence with plasma clearance and breath test
    • 35. Rost KL, Roots I. Accelerated caffeine metabolism after omeprazole treatment is indicated by urinary metabolite ratios: coincidence with plasma clearance and breath test. Clin Pharmacol Ther 1994;55:402-11.
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 402-411
    • Rost, K.L.1    Roots, I.2
  • 36
    • 0031854072 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic changes in the elderly. Clinical implications
    • 36. Haemmerlein A, Derendorf H, Lowenthal DT. Pharmacokinetic and pharmacodynamic changes in the elderly. Clinical implications. Clin Pharmacokinet 1998;35:49-64.
    • (1998) Clin Pharmacokinet , vol.35 , pp. 49-64
    • Haemmerlein, A.1    Derendorf, H.2    Lowenthal, D.T.3
  • 37
    • 0025786589 scopus 로고
    • Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin
    • 37. Smith DA, Chandler MHH, Shedlofsky SI, Wedlund PJ, Blouin RA. Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin. Br J Clin Pharmacol 1991;32:735-9.
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 735-739
    • Smith, D.A.1    Chandler, M.H.H.2    Shedlofsky, S.I.3    Wedlund, P.J.4    Blouin, R.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.