Quantitative determination of pravastatin and its biotransformation products in human serum by turbo ion spray LC/MS/MS

Journal of Pharmaceutical and Biomedical Analysis

Volumn 23, Issue 5, 2000, Pages 851-866

  Mulvana, Daniel ^a   Jemal, Mohammed ^b   Coates Pulver, Sabine ^a  

^a Adv BioAnalytical Services Inc   (United States)

^b Bioanalytical Research   (United States)

Author keywords

Human serum; Hydrolysis; Lactonization; LC MS MS; Pravastatin; Quantitative determination

Indexed keywords

ANTILIPEMIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LACTONE; PRAVASTATIN; SQ 31906; SQ 31906 D5; SQ 33469; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG TRANSFORMATION; HUMAN; HYDROLYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; QUALITY CONTROL; SERUM;

ANTICHOLESTEREMIC AGENTS; BIOTRANSFORMATION; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; HUMAN; INDICATORS AND REAGENTS; PRAVASTATIN; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; SOLUTIONS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTRUM ANALYSIS, MASS;

EID: 0033834358     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(00)00372-1     Document Type: Article

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