FGF-mediated mesoderm induction involves the Src-family kinase Laloo

Nature

Volumn 394, Issue 6696, 1998, Pages 904-908

  Weinstein, Daniel C ^a   Marden, Jennifer ^a   Carnevali, Francesca ^a,b   Hemmati Brivanlou, Ali ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 1;

ANIMAL EXPERIMENT; ARTICLE; CELL SPECIFICITY; EMBRYO DEVELOPMENT; GROWTH REGULATION; MESODERM; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CULTURE TECHNIQUES; DNA, COMPLEMENTARY; EMBRYONIC INDUCTION; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MESODERM; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; RAS PROTEINS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; XENOPUS; XENOPUS PROTEINS;

EID: 0032572802     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/29808     Document Type: Article

References (30)

1. Klein, P. S. & Melton, D. A. Hormonal regulation of embryogenesis: the formation of mesoderm in Xenopus laevis. Endocr. Rev. 15, 326-341 (1994).
2. Brown, M. T. & Cooper, J. A. Regulation, substrates and functions of src. Biochim. Biophys. Acta 1287, 121-149 (1996).
3. Smith, J. C., Price, B. M. J., Green, J. B. A., Weigel, D. & Herrmann, B. G. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87 (1991).
4. Smith, W. C. & Harland, R. M. Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center. Cell 67, 753-765 (1991).
5. Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K. & DeRobertis, E. M. Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790 (1994).
6. Wright, C. V. E., Morita, E. A., Wilkin, D. J. & DeRobertis, E. M. The Xenopus X1Hbox6 homeo protein, a marker of posterior neural induction, is expressed in proliferating neurons. Development 109, 225-234 (1990).
7. Kintner, C. R. & Melton, D. A. Expression of Xenopus NCAM RNA in ectoderm is an early response to neural induction. Development 99, 311-325 (1987).
8. Mohun, T. J., Brennan, S., Dathan, N., Fairman, S. & Gurdon, J. B. Cell type-specific activation of actin genes in the early amphibian embryo. Nature 311, 716-721 (1984).
9. Lagna, G., Hata, A., Hemmati-Brivanlou, A. & Massague, J. Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways. Nature 383, 832-836 (1996).
10. Amaya, E., Musci, T. J. & Kirschner, M. W. Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66, 257-270 (1991).
11. ras in Xenopus mesoderm induction. Nature 357, 252-255 (1992).
12. MacNicol, A. M., Muslin, A. J. & Williams, L. T. Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF. Cell 73, 571-584 (1993).
13. LaBonne, C. & Whitman, M. Mesoderm induction by activin requires FGF-mediated intracellular signals. Development 120, 463-472 (1994).
14. LaBonne, C., Burke, B. & Whitman, M. Role of MAP kinase in mesoderm induction and axial patterning during Xenopus development. Development 121, 1475-1486 (1995).
15. Gotoh, Y., Masuyama, N., Suzuki, A., Ueno, N. & Nishida, E. Involvement of the MAP kinase cascade in Xenopus mesoderm induction. EMBO J. 14, 2491-2498 (1995).
16. Umbhauer, M., Marshall, C. J., Mason, C. S., Old, R. W. & Smith, J. C. Mesoderm induction in Xenopus caused by activation of MAP kinase. Nature 376, 58-62 (1995).
17. Northrop, J. et al. BMP-4 regulates the dorsal-ventral differences in FGF/MAPKK-mediated mesoderm induction in Xenopus. Dev. Biol. 172, 242-252 (1995).
18. Amaya, E. & Kroll, K. L. Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation. Development 122, 3173-3183 (1996).
19. Cornell, R. A. & Kimelman, D. Activin-mediated mesoderm induction requires FGF. Development 120, 453-462 (1994).
20. Tang, T. L., Freeman, R. M. Jr, O'Reilly, A. M., Neel, B. G. & Sokol, S. Y. The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development. Cell 80, 473-483 (1995).
21. LaBonne, C. & Whitman, M. Localization of MAP kinase activity in early Xenopus embryos: implications for endogenous FGF signaling. Dev. Biol. 183, 9-20 (1997).
22. Isaacs, H. V., Pownall, M. E. & Slack, J. M. W. eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J. 13, 4469-4481 (1994).
23. Schulte-Merker, S. & Smith, J. C. Mesoderm formation in response to Brachyury requires FGF signaling. Curr. Biol. 5, 62-67 (1995).
24. Parsons, J. T. & Parsons, S. J. Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways. Curr. Opin. Cell Biol. 9, 187-192 (1997).
25. Lustig, K. D., Kroll, K. L., Sun, E. E. & Kirschner, M. W. Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation. Development 122, 4001-4012 (1996).
26. Hemmati-Brivanlou, A. & Melton, D. A. Inhibition of activin receptor signaling promotes neuralization in Xenopus. Cell 77, 273-281 (1994).
27. Harris, W. A. & Hartenstein, V. Neuronal determination without cell division in Xenopus embryos. Neuron 6, 499-515 (1991).
28. Kintner, C. R. & Brockes, J. P. Monoclonal antibodies identify blastemal cells derived from dedifferentiating muscle in newt limb regeneration. Nature 308, 67-69 (1984).
29. Krieg, P., Varnum, S., Wormington, M. & Melton, D. A. The mRNA encoding elongation factor 1α (EF-1α) is a major transcript at the mid-blastula transition in Xenopus. Dev. Biol. 133, 93-100 (1989).
30. Bassez, T., Paris, J., Omilli, F., Dorel, C. & Osborne, H. B. Post-transcriptional regulation of ornithine decarboxylase in Xenopus laevis oocytes. Development 110, 955-962 (1990).