메뉴 건너뛰기




Volumn 11, Issue 2 I, 2005, Pages 529-536

The thioredoxin-1 inhibitor 1-methylpropyl 2-imidazolyl disulfide (PX-12) decreases vascular permeability in tumor xenografts monitored by dynamic contrast enhanced magnetic resonance imaging

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLPROPYL 2 IMIDAZOLYLDISULFIDE; ANTINEOPLASTIC AGENT; BOVINE SERUM ALBUMIN; CONTRAST MEDIUM; GADOLINIUM PENTETATE; IMIDAZOLE DERIVATIVE; PROTEIN INHIBITOR; PX 12; THIOREDOXIN; THIOREDOXIN 1 INHIBITOR; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 12244275240     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (57)

References (72)
  • 1
    • 0034047595 scopus 로고    scopus 로고
    • Applications of magnetic resonance in model systems: Cancer therapeutics
    • Evelhoch JL, Gillies RJ, Karczmar GS, et al. Applications of magnetic resonance in model systems: cancer therapeutics. Neoplasia 2000;2:152-65.
    • (2000) Neoplasia , vol.2 , pp. 152-165
    • Evelhoch, J.L.1    Gillies, R.J.2    Karczmar, G.S.3
  • 2
    • 0034006104 scopus 로고    scopus 로고
    • Applications of magnetic resonance in model systems: Tumor biology and physiology
    • Gillies RJ, Bhujwalla ZM, Evelhoch J, et al. Applications of magnetic resonance in model systems: tumor biology and physiology. Neoplasia 2000;2:139-51.
    • (2000) Neoplasia , vol.2 , pp. 139-151
    • Gillies, R.J.1    Bhujwalla, Z.M.2    Evelhoch, J.3
  • 3
    • 0033770605 scopus 로고    scopus 로고
    • In vivo monitoring of tumor angiogenesis with MR imaging
    • Brasch RC, Li KC, Husb JE, et al. In vivo monitoring of tumor angiogenesis with MR imaging. Acad Radiol 2000;7:812-23.
    • (2000) Acad Radiol , vol.7 , pp. 812-823
    • Brasch, R.C.1    Li, K.C.2    Husb, J.E.3
  • 4
    • 0035181988 scopus 로고    scopus 로고
    • Magnetic resonance imaging applications in the evaluation of tumor angiogenesis
    • Neeman M, Provenzale JM, Dewhirst MW. Magnetic resonance imaging applications in the evaluation of tumor angiogenesis. Semin Radiat Oncol 2001;11:70-82.
    • (2001) Semin Radiat Oncol , vol.11 , pp. 70-82
    • Neeman, M.1    Provenzale, J.M.2    Dewhirst, M.W.3
  • 5
    • 10744228207 scopus 로고    scopus 로고
    • Correlation of dynamic contrast enhancement MRI parameters with microvessel density and VEGF for assessment of angiogenesis in breast cancer
    • Su MY, Cheung YC, Fruehauf JP, et al. Correlation of dynamic contrast enhancement MRI parameters with microvessel density and VEGF for assessment of angiogenesis in breast cancer. J Magn Reson Imaging 2003;18:467-77.
    • (2003) J Magn Reson Imaging , vol.18 , pp. 467-477
    • Su, M.Y.1    Cheung, Y.C.2    Fruehauf, J.P.3
  • 6
    • 0346752528 scopus 로고    scopus 로고
    • Use of dynamic contrast-enhanced MRI to evaluate acute treatment with ZD6474, a VEGF signaling inhibitor, in PC-3 prostate tumours
    • Checkley D, Tessier JJ, Kendrew J, Waterton JC, Wedge SR. Use of dynamic contrast-enhanced MRI to evaluate acute treatment with ZD6474, a VEGF signaling inhibitor, in PC-3 prostate tumours. Br J Cancer 2003;17;89:1889-95.
    • (2003) Br J Cancer , vol.17 , Issue.89 , pp. 1889-1895
    • Checkley, D.1    Tessier, J.J.2    Kendrew, J.3    Waterton, J.C.4    Wedge, S.R.5
  • 7
    • 0029787388 scopus 로고    scopus 로고
    • Breast lesions: Correlation of contrast medium enhancement patterns on MR images with histopathologic findings and tumor angiogenesis
    • Buadu LD, Murakami J, Murayama S, et al. Breast lesions: correlation of contrast medium enhancement patterns on MR images with histopathologic findings and tumor angiogenesis. Radiology 1996;200:639-49.
    • (1996) Radiology , vol.200 , pp. 639-649
    • Buadu, L.D.1    Murakami, J.2    Murayama, S.3
  • 8
    • 0031723118 scopus 로고    scopus 로고
    • Angiogenic activity of cervical carcinoma: Assessment by functional magnetic resonance imaging-based parameters and a histomorphological approach in correlation with disease outcome
    • Hawighorst H, Weikel W, Knapstein PG, et al. Angiogenic activity of cervical carcinoma: assessment by functional magnetic resonance imaging-based parameters and a histomorphological approach in correlation with disease outcome. Clin Cancer Res 1998;4:2305-12.
    • (1998) Clin Cancer Res , vol.4 , pp. 2305-2312
    • Hawighorst, H.1    Weikel, W.2    Knapstein, P.G.3
  • 9
    • 0032875831 scopus 로고    scopus 로고
    • MR microcirculation assessment in cervical cancer: Correlations with histomorphological tumor markers and clinical outcome
    • Mayr NA, Hawighorst H, Yuh WT, Essig M, Magnotta VA, Knopp MV. MR microcirculation assessment in cervical cancer: correlations with histomorphological tumor markers and clinical outcome. J Magn Reson Imaging 1999;10:267-76.
    • (1999) J Magn Reson Imaging , vol.10 , pp. 267-276
    • Mayr, N.A.1    Hawighorst, H.2    Yuh, W.T.3    Essig, M.4    Magnotta, V.A.5    Knopp, M.V.6
  • 10
    • 0036189478 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging as a surrogate marker of tumor response to anti-angiogenic therapy in a xenograft model of glioblastoma multiforme
    • Gossmann A, Helbich TH, Kuriyama N, et al. Dynamic contrast-enhanced magnetic resonance imaging as a surrogate marker of tumor response to anti-angiogenic therapy in a xenograft model of glioblastoma multiforme. J Magn Reson Imaging 2002;15:233-40.
    • (2002) J Magn Reson Imaging , vol.15 , pp. 233-240
    • Gossmann, A.1    Helbich, T.H.2    Kuriyama, N.3
  • 11
    • 0347615101 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: Results from two phase I studies
    • Morgan B, Thomas AL, Drevs J, et al. Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: results from two phase I studies. J Clin Oncol 2003;21:3955-64.
    • (2003) J Clin Oncol , vol.21 , pp. 3955-3964
    • Morgan, B.1    Thomas, A.L.2    Drevs, J.3
  • 12
    • 2442716283 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging rapidly indicates vessel regression in human squamous cell carcinomas grown in nude mice caused by VEGF receptor 2 blockade with DC101
    • Kiessling F, Farhan N, Lichy MP, et al. Dynamic contrast-enhanced magnetic resonance imaging rapidly indicates vessel regression in human squamous cell carcinomas grown in nude mice caused by VEGF receptor 2 blockade with DC101. Neoplasia 2004;6:213-23.
    • (2004) Neoplasia , vol.6 , pp. 213-223
    • Kiessling, F.1    Farhan, N.2    Lichy, M.P.3
  • 13
    • 0024190661 scopus 로고
    • Albumin labeled with Gd-DTPA: An intravascular contrast-enhancing agent for magnetic resonance blood pool imaging: Preparation and characterization
    • Ogan MD. Albumin labeled with Gd-DTPA: An intravascular contrast-enhancing agent for magnetic resonance blood pool imaging: preparation and characterization. Invest Radiol 1988;23:961.
    • (1988) Invest Radiol , vol.23 , pp. 961
    • Ogan, M.D.1
  • 14
    • 0031421953 scopus 로고    scopus 로고
    • Assessing tumor angiogenesis using macromolecular MR imaging contrast media
    • Brasch R, Pham C, Shames D, et al. Assessing tumor angiogenesis using macromolecular MR imaging contrast media. J Magn Reson Imaging 1997;7:68-74.
    • (1997) J Magn Reson Imaging , vol.7 , pp. 68-74
    • Brasch, R.1    Pham, C.2    Shames, D.3
  • 15
    • 0031012760 scopus 로고    scopus 로고
    • A MRI spatial mapping technique for microvascular permeability and tissue blood volume based on macromolecular contrast agent distribution
    • Demsar F, Roberts TP, Schwickert HC, et al. A MRI spatial mapping technique for microvascular permeability and tissue blood volume based on macromolecular contrast agent distribution. Magn Reson Med 1997;37:236-42.
    • (1997) Magn Reson Med , vol.37 , pp. 236-242
    • Demsar, F.1    Roberts, T.P.2    Schwickert, H.C.3
  • 16
    • 0031886171 scopus 로고    scopus 로고
    • Tumor characterization with dynamic contrast-enhanced MRI using MR contrast agents of various molecular weights
    • Su MY, Muhler A, Lao X, Nalcioglu O. Tumor characterization with dynamic contrast-enhanced MRI using MR contrast agents of various molecular weights. Magn Reson Med 1998;39:259-69.
    • (1998) Magn Reson Med , vol.39 , pp. 259-269
    • Su, M.Y.1    Muhler, A.2    Lao, X.3    Nalcioglu, O.4
  • 17
    • 0031688688 scopus 로고    scopus 로고
    • Correlation of dynamic contrast-enhanced MR imaging with histologic tumor grade: Comparison of macromolecular and small-molecular contrast media
    • Daldrup H, Shames DM, Wendland M, et al. Correlation of dynamic contrast-enhanced MR imaging with histologic tumor grade: comparison of macromolecular and small-molecular contrast media. AJR Am J Roentgenol 1998;171:941-9.
    • (1998) AJR Am J Roentgenol , vol.171 , pp. 941-949
    • Daldrup, H.1    Shames, D.M.2    Wendland, M.3
  • 18
    • 0032888214 scopus 로고    scopus 로고
    • Prostate cancer tumor grade differentiation with dynamic contrast-enhariced MR imaging in the rat: Comparison of macromolecular and small-molecular contrast media-preliminary experience
    • Gossmann A, Okuhata Y, Shames DM, et al. Prostate cancer tumor grade differentiation with dynamic contrast-enhariced MR imaging in the rat: comparison of macromolecular and small-molecular contrast media-preliminary experience. Radiology 1999;213:265-72.
    • (1999) Radiology , vol.213 , pp. 265-272
    • Gossmann, A.1    Okuhata, Y.2    Shames, D.M.3
  • 19
    • 0036333723 scopus 로고    scopus 로고
    • Tumor microvascular changes to anti-angiogenic treatment assessed by MR contrast media of different molecular weights
    • Roberts TP, Turetschek K, Preda A, et al. Tumor microvascular changes to anti-angiogenic treatment assessed by MR contrast media of different molecular weights. Acad Radiol 2002;9 Suppl 2:S511-3.
    • (2002) Acad Radiol , vol.9 , Issue.SUPPL. 2
    • Roberts, T.P.1    Turetschek, K.2    Preda, A.3
  • 20
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber H-P, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003;9:669-84.
    • (2003) Nat Med , vol.9 , pp. 669-684
    • Ferrara, N.1    Gerber, H.-P.2    LeCouter, J.3
  • 21
    • 0033867776 scopus 로고    scopus 로고
    • Hypoxia modulated gene expression: Angiogenesis, metastasis and therapeutic exploitation
    • Dachs GU, Tozer GM. Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation. Eur J Cancer 2000;36:1649-60.
    • (2000) Eur J Cancer , vol.36 , pp. 1649-1660
    • Dachs, G.U.1    Tozer, G.M.2
  • 22
    • 0032790131 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer
    • Yonemura Y, Endo Y, Fujita H, et al. Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer. Clin Cancer Res 1999;5:1823-9.
    • (1999) Clin Cancer Res , vol.5 , pp. 1823-1829
    • Yonemura, Y.1    Endo, Y.2    Fujita, H.3
  • 24
    • 0033010512 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is upregulated in early premalignant stage of colorectal tumour progression
    • Wong MP, Cheung N, Yuen ST, Leung SY, Chung LP. Vascular endothelial growth factor is upregulated in early premalignant stage of colorectal tumour progression. Int J Cancer 1999;81:845-50.
    • (1999) Int J Cancer , vol.81 , pp. 845-850
    • Wong, M.P.1    Cheung, N.2    Yuen, S.T.3    Leung, S.Y.4    Chung, L.P.5
  • 25
    • 0031774796 scopus 로고    scopus 로고
    • The effect of antibody against vascular endothelial growth factor on tumor growth and metastasis
    • Wang G, Dong Z, Xu G, et al. The effect of antibody against vascular endothelial growth factor on tumor growth and metastasis. J Cancer Res Clin Oncol 1998;124:615-20.
    • (1998) J Cancer Res Clin Oncol , vol.124 , pp. 615-620
    • Wang, G.1    Dong, Z.2    Xu, G.3
  • 26
    • 0037096814 scopus 로고    scopus 로고
    • A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin A-4 phosphate on a single dose intravenous schedule in patients with advanced cancer
    • Dowlati A, Robertson K, Cooney M, et al. A phase I pharmacokinetic and translational study of the novel vascular targeting agent combretastatin A-4 phosphate on a single dose intravenous schedule in patients with advanced cancer. Cancer Res 2002;62:3408-16.
    • (2002) Cancer Res , vol.62 , pp. 3408-3416
    • Dowlati, A.1    Robertson, K.2    Cooney, M.3
  • 27
    • 0347615101 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: Results from two phase I studies
    • Morgan B, Thomas AL, Drevs J, et al. Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: results from two phase I studies. J Clin Oncol 2003;21:3955-64.
    • (2003) J Clin Oncol , vol.21 , pp. 3955-3964
    • Morgan, B.1    Thomas, A.L.2    Drevs, J.3
  • 28
    • 0026716332 scopus 로고
    • Effects of bradykinin on the hemodynamics of tumor and granulating normal tissue microvasculature
    • Dewhirst MW, Vinuya RZ, Ong ET, et al. Effects of bradykinin on the hemodynamics of tumor and granulating normal tissue microvasculature. Radiat Res 1992;130:345-54.
    • (1992) Radiat Res , vol.130 , pp. 345-354
    • Dewhirst, M.W.1    Vinuya, R.Z.2    Ong, E.T.3
  • 29
    • 0023891889 scopus 로고
    • Increased vascular permeability in organs mediated by the systemic administration of lymphokine activated killer cell and recombinant interleukin-1 in mice
    • Ettinghausen SE, Puri RK, Rosenberg SA. Increased vascular permeability in organs mediated by the systemic administration of lymphokine activated killer cell and recombinant interleukin-1 in mice. J Natl Cancer Inst 1988;80:177-88.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 177-188
    • Ettinghausen, S.E.1    Puri, R.K.2    Rosenberg, S.A.3
  • 30
    • 0028025011 scopus 로고
    • Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows
    • Yuan F, Salehi HA, Boucher Y, Vasthare HS, Tuma RF, Jain RK. Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res 1994;54:4565-8.
    • (1994) Cancer Res , vol.54 , pp. 4565-4568
    • Yuan, F.1    Salehi, H.A.2    Boucher, Y.3    Vasthare, H.S.4    Tuma, R.F.5    Jain, R.K.6
  • 31
    • 0035956947 scopus 로고    scopus 로고
    • Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability
    • Fukumura D, Gohongi T, Kadambi A, et al. Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc Natl Acad Sci U S A 2001;98:2604-9.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2604-2609
    • Fukumura, D.1    Gohongi, T.2    Kadambi, A.3
  • 32
    • 0035029131 scopus 로고    scopus 로고
    • Properties and biological activities of thioredoxins
    • Powis G, Montfort WR. Properties and biological activities of thioredoxins. Annu Rev Pharmacol Toxicol 2001;41:261-95.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 261-295
    • Powis, G.1    Montfort, W.R.2
  • 33
    • 0021078605 scopus 로고
    • Evidence that the endogenous heat-stable glucocorticoid receptor-activating factor is thioredoxin
    • Grippo JF, Tienrungroj W, Dahmer MK, Housley PR, Pratt WB. Evidence that the endogenous heat-stable glucocorticoid receptor-activating factor is thioredoxin. J Biol Chem 1993;258:13658-64.
    • (1993) J Biol Chem , vol.258 , pp. 13658-13664
    • Grippo, J.F.1    Tienrungroj, W.2    Dahmer, M.K.3    Housley, P.R.4    Pratt, W.B.5
  • 34
    • 0029644240 scopus 로고
    • Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF-κB
    • Qin J, Clore GM, Kennedy WP, Hutch JR, Gronenbom AM. Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NF-κB. Structure 1994;3:289-97.
    • (1994) Structure , vol.3 , pp. 289-297
    • Qin, J.1    Clore, G.M.2    Kennedy, W.P.3    Hutch, J.R.4    Gronenbom, A.M.5
  • 35
    • 0033544915 scopus 로고    scopus 로고
    • Thioredoxin-dependent redox regulation of p53-mediated p21 activation
    • Ueno M, Masutani H, Jun Arai R, et al. Thioredoxin-dependent redox regulation of p53-mediated p21 activation. J Biol Chem 2001;274:35809-15.
    • (2001) J Biol Chem , vol.274 , pp. 35809-35815
    • Ueno, M.1    Masutani, H.2    Jun Arai, R.3
  • 36
    • 0036735392 scopus 로고    scopus 로고
    • The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1α protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis
    • Welsh SJ, Bellamy WT, Briehl MM, Powis G. The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1α protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis. Cancer Res 2002;62:5089-95.
    • (2002) Cancer Res , vol.62 , pp. 5089-5095
    • Welsh, S.J.1    Bellamy, W.T.2    Briehl, M.M.3    Powis, G.4
  • 37
    • 0025077481 scopus 로고
    • Redox regulation of fos and jun DNA-binding activity in vitro
    • Abate C, Patel L, Rauscher FJ, Curran T. Redox regulation of fos and jun DNA-binding activity in vitro. Science 1990;249:1157-61.
    • (1990) Science , vol.249 , pp. 1157-1161
    • Abate, C.1    Patel, L.2    Rauscher, F.J.3    Curran, T.4
  • 38
    • 0032080283 scopus 로고    scopus 로고
    • Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
    • Saitoh M, Nishitoh H, Fujii M, et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 1998;17:2596-606.
    • (1998) EMBO J , vol.17 , pp. 2596-2606
    • Saitoh, M.1    Nishitoh, H.2    Fujii, M.3
  • 39
    • 0033569457 scopus 로고    scopus 로고
    • Phage display identifies thioredoxin and superoxide dismutase as novel protein kinase C-interacting proteins: Thioredoxin inhibits protein kinase C-mediated phosphorylation of histone
    • Watson JA, Rumsby MG, Wolowacz RG. Phage display identifies thioredoxin and superoxide dismutase as novel protein kinase C-interacting proteins: thioredoxin inhibits protein kinase C-mediated phosphorylation of histone. Biochem J 1999;343:301-5.
    • (1999) Biochem J , vol.343 , pp. 301-305
    • Watson, J.A.1    Rumsby, M.G.2    Wolowacz, R.G.3
  • 40
    • 4143093730 scopus 로고    scopus 로고
    • Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: Providing a mechanism for the functional loss of PTEN's tumor suppressor activity
    • Meuillet E, Mahadevan D, Berggren M, Coon A, Powis G. Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: providing a mechanism for the functional loss of PTEN's tumor suppressor activity. Arch Biochem Biophys 2004;429:123-33.
    • (2004) Arch Biochem Biophys , vol.429 , pp. 123-133
    • Meuillet, E.1    Mahadevan, D.2    Berggren, M.3    Coon, A.4    Powis, G.5
  • 41
    • 0001445231 scopus 로고    scopus 로고
    • Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin
    • Chae HZ, Kim HJ, Kang SW, Rhee SG. Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin. Diabetes Res Clin Pract 1999;45:101-12.
    • (1999) Diabetes Res Clin Pract , vol.45 , pp. 101-112
    • Chae, H.Z.1    Kim, H.J.2    Kang, S.W.3    Rhee, S.G.4
  • 42
    • 0034055451 scopus 로고    scopus 로고
    • Expression of thioredoxin and glutaredoxin, redox-regulating proteins, in pancreatic cancer
    • Nakamura H, Bai J, Nishinaka Y, et al. Expression of thioredoxin and glutaredoxin, redox-regulating proteins, in pancreatic cancer. Cancer Detect Prev 2000;24:53-60.
    • (2000) Cancer Detect Prev , vol.24 , pp. 53-60
    • Nakamura, H.1    Bai, J.2    Nishinaka, Y.3
  • 43
    • 0026563593 scopus 로고
    • Expression and growth-promoting effect of adult T-cell leukemia-derived factor. A human thioredoxin homologue in hepatocellular carcinoma
    • Nakamum H, Masutani H, Tagaya Y, et al. Expression and growth-promoting effect of adult T-cell leukemia-derived factor. A human thioredoxin homologue in hepatocellular carcinoma. Cancer 1992;69:2091-7.
    • (1992) Cancer , vol.69 , pp. 2091-2097
    • Nakamum, H.1    Masutani, H.2    Tagaya, Y.3
  • 44
    • 0034797926 scopus 로고    scopus 로고
    • Thioredoxin expression is associated with lymph node status and prognosis in early operable non small cell lung cancer (NSCLC)
    • Kakolyris S, Giatromanolakim A, Koukourakis M, et al. Thioredoxin expression is associated with lymph node status and prognosis in early operable non small cell lung cancer (NSCLC). Clin Cancer Res 2001;7:3087-91.
    • (2001) Clin Cancer Res , vol.7 , pp. 3087-3091
    • Kakolyris, S.1    Giatromanolakim, A.2    Koukourakis, M.3
  • 45
    • 0034065729 scopus 로고    scopus 로고
    • Thioredoxin, a putative oncogene product, is overexpressed in gastric carcinoma and associated with increased proliferation and increased cell survival
    • Grogan TM, Fenoglio-Prieser C, Zeheb R, et al. Thioredoxin, a putative oncogene product, is overexpressed in gastric carcinoma and associated with increased proliferation and increased cell survival. Hum Pathol 2000;31:475-81.
    • (2000) Hum Pathol , vol.31 , pp. 475-481
    • Grogan, T.M.1    Fenoglio-Prieser, C.2    Zeheb, R.3
  • 46
    • 0042991494 scopus 로고    scopus 로고
    • Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival
    • Raffel J, Bhattacharyya AB, Gallegos A, et al. Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival. J Lab Clin Med 2002;142:46-51.
    • (2002) J Lab Clin Med , vol.142 , pp. 46-51
    • Raffel, J.1    Bhattacharyya, A.B.2    Gallegos, A.3
  • 47
    • 0032055646 scopus 로고    scopus 로고
    • Mechanisms of inhibition of the thioredoxin growth factor system by antitumor 2-imidazolyl disulfides
    • Kirkpatrick DL, Kuperus M, Dowdeswell M, et al. Mechanisms of inhibition of the thioredoxin growth factor system by antitumor 2-imidazolyl disulfides. Biochem Pharmacol 1998;55:987-94.
    • (1998) Biochem Pharmacol , vol.55 , pp. 987-994
    • Kirkpatrick, D.L.1    Kuperus, M.2    Dowdeswell, M.3
  • 48
    • 33645025477 scopus 로고    scopus 로고
    • Results from phase I study of PX-12, a thioredoxin inhibitor in patients with advanced solid malignancies
    • Kirkpatrick L, Dragovich T, Ramahathan R, et al. Results from phase I study of PX-12, a thioredoxin inhibitor in patients with advanced solid malignancies. Proc Am Assoc Clin Oncol 2004;22:217.
    • (2004) Proc Am Assoc Clin Oncol , vol.22 , pp. 217
    • Kirkpatrick, L.1    Dragovich, T.2    Ramahathan, R.3
  • 50
    • 1242272854 scopus 로고    scopus 로고
    • Multiple regulatory pathways of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in tumors
    • Mukhopadhyay D, Datta K. Multiple regulatory pathways of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in tumors. Semin Cancer Biol 2004;14:123-30.
    • (2004) Semin Cancer Biol , vol.14 , pp. 123-130
    • Mukhopadhyay, D.1    Datta, K.2
  • 51
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003;3:721-32.
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 52
    • 0142144338 scopus 로고    scopus 로고
    • The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1α and vascular endothelial growth factor formation
    • Welsh SJ, Williams RR, Birmingham A, Newman DJ, Kirkpatrick DL, Powis G. The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1α and vascular endothelial growth factor formation. Mol Cancer Ther 2003;2:235-43.
    • (2003) Mol Cancer Ther , vol.2 , pp. 235-243
    • Welsh, S.J.1    Williams, R.R.2    Birmingham, A.3    Newman, D.J.4    Kirkpatrick, D.L.5    Powis, G.6
  • 53
    • 0035052324 scopus 로고    scopus 로고
    • Vascular differences detected by MRI for metastatic versus nonmetastatic breast and prostate cancer xenografts
    • Bhujwalla ZM, Artemov D, Natarajan K, Ackerstaff E, Solaiyappan M. Vascular differences detected by MRI for metastatic versus nonmetastatic breast and prostate cancer xenografts. Neoplasia 2001;3:143-53.
    • (2001) Neoplasia , vol.3 , pp. 143-153
    • Bhujwalla, Z.M.1    Artemov, D.2    Natarajan, K.3    Ackerstaff, E.4    Solaiyappan, M.5
  • 54
    • 0020488534 scopus 로고
    • Rat liver thioredoxin and thioredoxin reductase: Purification and characterization
    • Luthman M, Holmgren A. Rat liver thioredoxin and thioredoxin reductase: purification and characterization. Biochemistry 1982;21:6628-33.
    • (1982) Biochemistry , vol.21 , pp. 6628-6633
    • Luthman, M.1    Holmgren, A.2
  • 55
    • 0037242284 scopus 로고    scopus 로고
    • Reduction of vascular and permeable regions in solid tumors detected by macromolecular contrast magnetic resonance imaging after treatment with antiangiogenic agent TNP-470
    • Bhujwalla ZM, Artemov D, Natarajan K, Solaiyappan M, Kollars P, Kristjansen PE. Reduction of vascular and permeable regions in solid tumors detected by macromolecular contrast magnetic resonance imaging after treatment with antiangiogenic agent TNP-470. Clin Cancer Res 2003;9:355-62.
    • (2003) Clin Cancer Res , vol.9 , pp. 355-362
    • Bhujwalla, Z.M.1    Artemov, D.2    Natarajan, K.3    Solaiyappan, M.4    Kollars, P.5    Kristjansen, P.E.6
  • 56
    • 0034060928 scopus 로고    scopus 로고
    • Quantitative measurement of microvascular permeability in human brain tumors achieved using dynamic contrast-enhanced MR imaging: Correlation with histologic grade
    • Roberts HC, Roberts TP, Brasch RC, Dillon WP. Quantitative measurement of microvascular permeability in human brain tumors achieved using dynamic contrast-enhanced MR imaging: correlation with histologic grade. AJNR Am J Neuroradiol 2000;21:891-9.
    • (2000) AJNR Am J Neuroradiol , vol.21 , pp. 891-899
    • Roberts, H.C.1    Roberts, T.P.2    Brasch, R.C.3    Dillon, W.P.4
  • 57
    • 0036794518 scopus 로고    scopus 로고
    • Dynamic contrast-enhanced MRI in clinical oncology: Current status and future directions
    • Padhani AR. Dynamic contrast-enhanced MRI in clinical oncology: current status and future directions. J Magn Reson Imaging 2002;16:407-22.
    • (2002) J Magn Reson Imaging , vol.16 , pp. 407-422
    • Padhani, A.R.1
  • 58
    • 0037009827 scopus 로고    scopus 로고
    • Molecular imaging and biological evaluation of HuMV833 anti-VEGF antibody: Implications for trial design of antiangiogenic antibodies
    • Jayson GC, Zweit J, Jackson A, et al. Molecular imaging and biological evaluation of HuMV833 anti-VEGF antibody: implications for trial design of antiangiogenic antibodies. J Natl Cancer Inst 2002;94:1484-93.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1484-1493
    • Jayson, G.C.1    Zweit, J.2    Jackson, A.3
  • 59
    • 0036331674 scopus 로고    scopus 로고
    • A target mediated model to describe pharmacokinetic and hemodynamic effects of recombinant human vascular endothelial growth factor in humans
    • Eppler SM, Combs DL, Henry TD, et al. A target mediated model to describe pharmacokinetic and hemodynamic effects of recombinant human vascular endothelial growth factor in humans. Clin Pharmacol Ther 2002;72:20-32.
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 20-32
    • Eppler, S.M.1    Combs, D.L.2    Henry, T.D.3
  • 60
    • 18444364209 scopus 로고    scopus 로고
    • Stabilization of vascular endothelial growth factor mRNA by hypoxia-inducible factor 1
    • Liu LX, Luo LH, Date T. Stabilization of vascular endothelial growth factor mRNA by hypoxia-inducible factor 1. Biochem Biophys Res Commun 2002;29:908-14.
    • (2002) Biochem Biophys Res Commun , vol.29 , pp. 908-914
    • Liu, L.X.1    Luo, L.H.2    Date, T.3
  • 61
    • 0035001708 scopus 로고    scopus 로고
    • Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases
    • Akaike WJ, Hayashida T, Okamoto T, Okuyama A, Maeda H. Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases. Jpn J Cancer Res 2001;92:439-51.
    • (2001) Jpn J Cancer Res , vol.92 , pp. 439-451
    • Akaike, W.J.1    Hayashida, T.2    Okamoto, T.3    Okuyama, A.4    Maeda, H.5
  • 62
    • 0030238701 scopus 로고    scopus 로고
    • Nitric oxide-induced inhibition of lung endothelial cell nitric oxide synthase via interaction with allosteric thiols: Role of thioredoxin in regulation of catalytic activity
    • Patel JM, Zhang J, Block ER. Nitric oxide-induced inhibition of lung endothelial cell nitric oxide synthase via interaction with allosteric thiols: role of thioredoxin in regulation of catalytic activity. Am J Respir Cell Mol Biol 1996;15:410-9.
    • (1996) Am J Respir Cell Mol Biol , vol.15 , pp. 410-419
    • Patel, J.M.1    Zhang, J.2    Block, E.R.3
  • 63
    • 0026443077 scopus 로고
    • Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway
    • Rubartelli A, Bajetto A, Allavena G, Wollman E, Sitia R. Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway. J Biol Chem 1992;267:24161-4.
    • (1992) J Biol Chem , vol.267 , pp. 24161-24164
    • Rubartelli, A.1    Bajetto, A.2    Allavena, G.3    Wollman, E.4    Sitia, R.5
  • 64
    • 0028818288 scopus 로고
    • Cell growth stimulation by the redox protein thioredoxin occurs by a novel helper mechanism
    • Gasdaska JR, Berggren M, Powis G. Cell growth stimulation by the redox protein thioredoxin occurs by a novel helper mechanism. Cell Growth Differ 1995;6:1643-50.
    • (1995) Cell Growth Differ , vol.6 , pp. 1643-1650
    • Gasdaska, J.R.1    Berggren, M.2    Powis, G.3
  • 65
    • 0028894636 scopus 로고
    • Interleukin 2-induced increase of vascular permeability without decrease of the intravascular albumin pool
    • Ballmer-Weber B, Dummer R, Kung E, Burg G, Ballmer P. Interleukin 2-induced increase of vascular permeability without decrease of the intravascular albumin pool. Br J Cancer 1995;71:78-82.
    • (1995) Br J Cancer , vol.71 , pp. 78-82
    • Ballmer-Weber, B.1    Dummer, R.2    Kung, E.3    Burg, G.4    Ballmer, P.5
  • 66
    • 0026892205 scopus 로고
    • Interleukin-2 directly increases albumin permeability of bovine and human vascular endothelium in vitro
    • Downie G, Ryan U, Hayes B, Friedman M. Interleukin-2 directly increases albumin permeability of bovine and human vascular endothelium in vitro. Am J Respir Cell Mol Biol 1992;7:58-65.
    • (1992) Am J Respir Cell Mol Biol , vol.7 , pp. 58-65
    • Downie, G.1    Ryan, U.2    Hayes, B.3    Friedman, M.4
  • 67
    • 0025836319 scopus 로고
    • Dual effects of N-ethylmaleimide on ethanol-induced gastric lesions in rats
    • Takeuchi K, Okada M, Niida H, Okabe S. Dual effects of N-ethylmaleimide on ethanol-induced gastric lesions in rats. Dig Dis Sci 1991;36:870-9.
    • (1991) Dig Dis Sci , vol.36 , pp. 870-879
    • Takeuchi, K.1    Okada, M.2    Niida, H.3    Okabe, S.4
  • 68
    • 0036333725 scopus 로고    scopus 로고
    • MRI monitoring of tumor response to a novel VEGF tyrosine kinase inhibitor in an experimental breast cancer model
    • Turetschek K, Preda A, Floyd E, et al. MRI monitoring of tumor response to a novel VEGF tyrosine kinase inhibitor in an experimental breast cancer model. Acad Radiol 2002;2:S519-20.
    • (2002) Acad Radiol , vol.2
    • Turetschek, K.1    Preda, A.2    Floyd, E.3
  • 69
    • 10744232649 scopus 로고    scopus 로고
    • In vivo assessment of antiangiogenic activity of SU6668 in an experimental colon carcinoma model
    • Marzola P, Degrassi A, Calderan L, et al. In vivo assessment of antiangiogenic activity of SU6668 in an experimental colon carcinoma model. Clin Cancer Res 2004;10:739-50.
    • (2004) Clin Cancer Res , vol.10 , pp. 739-750
    • Marzola, P.1    Degrassi, A.2    Calderan, L.3
  • 70
    • 0036200834 scopus 로고    scopus 로고
    • Differential sensitivity of two adenocarcinoma xenografts to the anti-vascular drugs combretastatin A4 phosphate and 5,6-dimethylxanthenone-4- acetic acid, assessed using MRI and MRS
    • Beauregard DA, Pedley RB, Hill SA, Brindle KM. Differential sensitivity of two adenocarcinoma xenografts to the anti-vascular drugs combretastatin A4 phosphate and 5,6-dimethylxanthenone-4-acetic acid, assessed using MRI and MRS. NMR Biomed 2002;15:99-105.
    • (2002) NMR Biomed , vol.15 , pp. 99-105
    • Beauregard, D.A.1    Pedley, R.B.2    Hill, S.A.3    Brindle, K.M.4
  • 71
    • 10244279109 scopus 로고    scopus 로고
    • Decrease in tumor apparent permeability-surface area product to a MRI macromolecular contrast medium following angiogenesis inhibition with correlations to cytotoxic drug accumulation
    • Daldrup-Link H, Okuhata Y, Wolfe A, et al. Decrease in tumor apparent permeability-surface area product to a MRI macromolecular contrast medium following angiogenesis inhibition with correlations to cytotoxic drug accumulation. Microcirculation 2004;11:387-96.
    • (2004) Microcirculation , vol.11 , pp. 387-396
    • Daldrup-Link, H.1    Okuhata, Y.2    Wolfe, A.3
  • 72
    • 0013405842 scopus 로고    scopus 로고
    • MRI Evaluation of the effects of the vascular-targeting agent ZD6126 on tumor vasculature
    • DelProposto Z, LoRusso P, Latif Z, et al. MRI Evaluation of the effects of the vascular-targeting agent ZD6126 on tumor vasculature. Proc Am Soc Clin Oncol 2002;21:440.
    • (2002) Proc Am Soc Clin Oncol , vol.21 , pp. 440
    • DelProposto, Z.1    LoRusso, P.2    Latif, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.