The effect of antibody against vascular endothelial growth factor tumor growth and metastasis

Journal of Cancer Research and Clinical Oncology

Volumn 124, Issue 11, 1998, Pages 615-620

  Wang, Guiqi ^b   Dong, Zhiwei ^a   Xu, Guangwei ^b   Yang, Zhihua ^a   Shou, Chengchao ^b   Wang, Naiqin ^b   Liu, Tong ^b  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

Angiogenesis; Antibody; Metastasis; Tumor; Vascular endothelial growth factor

Indexed keywords

IODINE 131; MONOCLONAL ANTIBODY; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CANCER IMMUNOTHERAPY; EXPERIMENTAL MODEL; LUNG METASTASIS; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SARCOMA; STOMACH CANCER; TUMOR GROWTH;

ANIMALS; ANTIBODIES, MONOCLONAL; ENDOTHELIAL GROWTH FACTORS; FEMALE; HUMANS; IODINE RADIOISOTOPES; LUNG NEOPLASMS; LYMPHOKINES; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; SARCOMA 180; STOMACH NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0031774796     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004320050223     Document Type: Article

References (17)

1. Borgstrom P, Hillan KJ, Sriramarao P, Ferrara N (1996) Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res 56:4032-4039
2. Denekamp J (1993) Angiogenesis, neovascular proliferation and vascular pathophysiology as targets for cancer therapy. Br J Radiol 66:181-196
3. Deroanne CF, Hajitou A, Calberg-Bacq CM, Nusgens BV, Lapiere CM (1997) Angiogenesis by fibroblast growth factor 4 is mediated through an autocrine up-regulation of vascular endothelial growth factor expression. Cancer Res 57:5590-5597
4. Dong ZW, Wei SM, Zhang MY, Li ZP, Wan WH, Mu ZY, Liu BG, Ji JF, Xu GW (1995) Use of monoclonal antibody 3H11. Chin Biol Ther Cancers 2:84-87
5. Folkman J (1971) Tumor angiogenesis:therapeutic implication. N Engl J Med 285:1182-1186
6. Folkman J (1990) What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82:4-6
7. Folkman J, Klaysburn M (1987) Angiogenetic factor. Science 235:442-447
8. 2MA-891) with high rate of spontaneous metastases in the lung. Acta. Acad Med Sin 16:147-152
9. Inoue K, Ozeki Y, Suganuma T, Sugiura Y, Tanaka S (1997) Vascular endothelial growth factor expression in primary esophageal squamous cell carcinoma. Cancer 79:206-213
10. Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS, Ferrara N (1993) Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo. Nature 362:841-844
11. Presta LG, Chen H, O'Connor SJ, Chisholm V, Meng YG, Krummen L, Winkler M, Ferrara N (1997) Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 57:4593-4599
12. Rosenthal RA, Megyesi JF, Henzel WJ, Ferrara N, Folkman J (1990) Conditioned media from mouse sarcoma 180 cells contain vascular endothelial growth factor. Growth Factors 4: 53-59
13. Sakurada S, Kato T, Mashiba K, Mori S, Okamoto T (1996) Involvement of vascular endothelial growth factor in Kaposi's sarcoma associated with acquired immunodeficiency syndrom. Jpn J Cancer Res 87:1143-1152
14. Warren RS, Yuan H, Matli MR, Gillett NA, Ferrara N (1995) Regulation by vascular endothelial growth factor of human colon cancer tumorgenesis in a mouse model of experimental liver metastasis. J Clin Invest 95:1789-1797
15. Wang GQ, Wei SM, Guo Q, Xu GW, Dong ZW (1996) The distribution of vascular endothelial growth factor in normal and tumor tissues. J Beijing Med Univ 28:478
16. Yuan F, Chen Y, Dellian M, Safabakhsh N, Ferrara N, Jain RK (1996) Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc Natl Acad Sci USA 93:14765-14770
17. 131I labelled McAbs. Chin J Cancer Res 2:1-6