Decrease in tumor apparent permeability-surface area product to a MRI macromolecular contrast medium following angiogenesis inhibition with correlations to cytotoxic drug accumulation

Microcirculation

Volumn 11, Issue 5, 2004, Pages 387-396

  Daldrup Link, Heike E ^a   Okuhata, Yoshitaka ^a   Wolfe, Allan ^a   Srivastav, Sudesk ^a   Øie, Sven ^a   Ferrara, Napoleone ^b   Cohen, Robert L ^b   Shames, David M ^a   Brasch, Robert C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GENENTECH INC   (United States)

Author keywords

Angiogenesis inhibition; Apparent permeability surface area product; Chemotherapy; Macromolecular contrast media; MRI; VEGF

Indexed keywords

ANGIOGENESIS INHIBITOR; CISPLATIN; CONTRAST MEDIUM; CYTOTOXIC AGENT; FLUOROURACIL; GADOLINIUM PENTETATE ALBUMIN; VASCULOTROPIN ANTIBODY; WATER;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER MODEL; COMPARTMENT MODEL; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG TRANSPORT; DRUG TUMOR LEVEL; FEMALE; HUMAN; HUMAN CELL; MACROMOLECULE; MICROVASCULATURE; MOLECULAR WEIGHT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERMEABILITY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SURFACE PROPERTY; TUMOR VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTIBODIES; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CISPLATIN; CONTRAST MEDIA; DRUG SYNERGISM; FEMALE; FLUOROURACIL; HUMANS; MAGNETIC RESONANCE IMAGING; MODELS, BIOLOGICAL; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; PERMEABILITY; RATS; RATS, NUDE; TRANSPLANTATION, HETEROLOGOUS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 10244279109     PISSN: 10739688     EISSN: None     Source Type: Journal    
DOI: 10.1080/10739680490457665     Document Type: Article

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