Improvement of exogenous DNA nuclear importation by nuclear localization signal-bearing vectors: A promising way for non-viral gene therapy?

Biology of the Cell

Volumn 95, Issue 2, 2003, Pages 59-68

  Hébert, Eric ^a  

^a CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

Author keywords

DNA trafficking; Gene therapy; Importation; Nucleus; Vector

Indexed keywords

CELL NUCLEUS ANTIGEN; CORE PROTEIN; DIGITONIN; DNA; DOUBLE STRANDED DNA; EPSTEIN BARR VIRUS ANTIGEN; GLYCOPROTEIN; HAPTOCORRIN; HISTONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOFECTIN; LIPOSOME; LUCIFERASE; NUCLEAR PROTEIN; NUCLEAR RNA; OLIGONUCLEOTIDE; OLIGOSACCHARIDE; PEPTIDE; PEPTIDE DERIVATIVE; PLASMID DNA; PLASMID VECTOR; POLYMER; PROTAMINE; RNA POLYMERASE; SINGLE STRANDED DNA; STEROID RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SP1; UNINDEXED DRUG; VIRUS PROTEIN; VIRUS T ANTIGEN; VIRUS VECTOR;

ACTIVE TRANSPORT; ANIMAL; BINDING COMPETITION; BINDING KINETICS; CELL NUCLEUS; CHEMISTRY; COVALENT BOND; CYTOPLASM; DISSOCIATION; DNA VECTOR; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; HALF LIFE TIME; HIGH MOBILITY GROUP BOX DOMAIN; HUMAN; IN VITRO STUDY; INFECTION RISK; INTRACELLULAR TRANSPORT; METHODOLOGY; NONHUMAN; NONVIRAL GENE THERAPY; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR PORE COMPLEX; PRIORITY JOURNAL; PROTEIN DNA BINDING; RAT; REVIEW; TRANSGENE;

EID: 0038039166     PISSN: 02484900     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0248-4900(03)00007-8     Document Type: Review

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