-
2
-
-
0034175950
-
Chemotherapy for falciparum malaria: The armoury, the problems and the prospects
-
Winstanley P.A. Chemotherapy for falciparum malaria: the armoury, the problems and the prospects. Parasitol. Today. 16:2000;146-153.
-
(2000)
Parasitol. Today
, vol.16
, pp. 146-153
-
-
Winstanley, P.A.1
-
3
-
-
0037015614
-
Genome sequence of the human malaria parasite Plasmodium falciparum
-
Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K., Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 419:2002;498-511.
-
(2002)
Nature
, vol.419
, pp. 498-511
-
-
Gardner, M.J.1
Hall, N.2
Fung, E.3
White, O.4
Berriman, M.5
Hyman, R.W.6
Carlton, J.M.7
Pain, A.8
Nelson, K.E.9
Bowman, S.10
Paulsen, I.T.11
James, K.12
Eisen, J.A.13
Rutherford, K.14
Salzberg, S.L.15
Craig, A.16
Kyes, S.17
Chan, M.S.18
Nene, V.19
Shallom, S.J.20
Suh, B.21
Peterson, J.22
Angiuoli, S.23
Pertea, M.24
Allen, J.25
Selengut, J.26
Haft, D.27
Mather, M.W.28
Vaidya, A.B.29
Martin, D.M.30
Fairlamb, A.H.31
Fraunholz, M.J.32
Roos, D.S.33
Ralph, S.A.34
McFadden, G.I.35
Cummings, L.M.36
Subramanian, G.M.37
Mungall, C.38
Venter, J.C.39
Carucci, D.J.40
Hoffman, S.L.41
Newbold, C.42
Davis, R.W.43
Fraser, C.M.44
Barrell, B.45
more..
-
4
-
-
0036697233
-
Protein kinases as drug targets of parasitic protozoa
-
Doerig C., Meijer L., Mottram J. Protein kinases as drug targets of parasitic protozoa. Trends Parasitol. 18:2002;366-371.
-
(2002)
Trends Parasitol.
, vol.18
, pp. 366-371
-
-
Doerig, C.1
Meijer, L.2
Mottram, J.3
-
5
-
-
0037383322
-
GSK-3: Tricks of the trade for a multi-tasking kinase
-
Doble B.W., Woodgett J.R. GSK-3: tricks of the trade for a multi-tasking kinase. J. Cell Sci. 116:2003;1175-1186.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
7
-
-
0035477020
-
GSK3 takes centre stage more than 20 years after its discovery
-
Frame S., Cohen P. GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359:2001;1-16.
-
(2001)
Biochem. J.
, vol.359
, pp. 1-16
-
-
Frame, S.1
Cohen, P.2
-
8
-
-
0036629249
-
Wnt signal transduction: Kinase cogs in a nano-machine
-
Ding Y., Dale T. Wnt signal transduction: kinase cogs in a nano-machine. Trends Biochem. Sci. 27:2002;327-329.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 327-329
-
-
Ding, Y.1
Dale, T.2
-
9
-
-
0035967897
-
Regulation of GSK-3: A cellular multiprocessor
-
Harwood A.J. Regulation of GSK-3: a cellular multiprocessor. Cell. 29:2001;821-824.
-
(2001)
Cell
, vol.29
, pp. 821-824
-
-
Harwood, A.J.1
-
10
-
-
0036090823
-
Glycogen synthase kinase 3: An emerging therapeutic target
-
Eldar-Finkelman H. Glycogen synthase kinase 3: an emerging therapeutic target. Trends Mol. Med. 8:2002;126-132.
-
(2002)
Trends Mol. Med.
, vol.8
, pp. 126-132
-
-
Eldar-Finkelman, H.1
-
11
-
-
0033662579
-
Purification of GSK-3 by affinity chromatography on immobilised axin
-
Primot A., Baratte B., Gompel M., Borgne A., Liabeuf S., Romette J.L., Costantini F., Meijer L. Purification of GSK-3 by affinity chromatography on immobilised axin. Protein Expr. Purif. 20:2000;394-404.
-
(2000)
Protein Expr. Purif.
, vol.20
, pp. 394-404
-
-
Primot, A.1
Baratte, B.2
Gompel, M.3
Borgne, A.4
Liabeuf, S.5
Romette, J.L.6
Costantini, F.7
Meijer, L.8
-
12
-
-
0035006828
-
Cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo
-
Ostvold A.C., Norum J.H., Mathiesen S., Wanvik B., Sefland I., Grundt K. Cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo. Eur. J. Biochem. 268:2001;2430-2440.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2430-2440
-
-
Ostvold, A.C.1
Norum, J.H.2
Mathiesen, S.3
Wanvik, B.4
Sefland, I.5
Grundt, K.6
-
13
-
-
0033614949
-
The paullones, a series of cyclin-dependent kinase inhibitors: Synthesis, evaluation of CDK1/cyclin B inhibition, in vitro antitumor activity
-
Schultz C., Link A., Leost M., Zaharevitz D.W., Gussio R., Sausville E.A., Meijer L., Kunick C. The paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, in vitro antitumor activity. J. Med. Chem. 42:1999;2909-2919.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 2909-2919
-
-
Schultz, C.1
Link, A.2
Leost, M.3
Zaharevitz, D.W.4
Gussio, R.5
Sausville, E.A.6
Meijer, L.7
Kunick, C.8
-
14
-
-
0027962346
-
Plasmodium falciparum: The Pf332 antigen is secreted from the parasite by a brefeldin a - Dependent pathway and is translocated to the erythrocyte membrane via the Maurer's clefts
-
Hinterberg K., Scherf A., Gysin J., Toyoshima T., Aikawa M., Mazie J.C., Pereira da Silva L., Mattei D. Plasmodium falciparum: the Pf332 antigen is secreted from the parasite by a brefeldin A - dependent pathway and is translocated to the erythrocyte membrane via the Maurer's clefts. Exp. Parasitol. 79:1994;279-291.
-
(1994)
Exp. Parasitol.
, vol.79
, pp. 279-291
-
-
Hinterberg, K.1
Scherf, A.2
Gysin, J.3
Toyoshima, T.4
Aikawa, M.5
Mazie, J.C.6
Pereira Da Silva, L.7
Mattei, D.8
-
15
-
-
0026536681
-
The Pf332 gene of Plasmodium falciparum codes for a giant protein that is translocated from parasite to the membrane of infected erythrocytes
-
Mattei D., Scherf A. The Pf332 gene of Plasmodium falciparum codes for a giant protein that is translocated from parasite to the membrane of infected erythrocytes. Gene. 110:1992;71-79.
-
(1992)
Gene
, vol.110
, pp. 71-79
-
-
Mattei, D.1
Scherf, A.2
-
16
-
-
0035875098
-
Crystal structure of glycogen synthase kinase 3 β: Structural basis for phosphate-primed substrate specificity and autoinhibition
-
Dajani R., Fraser E., Roe S.M., Young N., Good V., Dale T.C., Pearl L.H. Crystal structure of glycogen synthase kinase 3 β: structural basis for phosphate-primed substrate specificity and autoinhibition. Cell. 105:2001;721-732.
-
(2001)
Cell
, vol.105
, pp. 721-732
-
-
Dajani, R.1
Fraser, E.2
Roe, S.M.3
Young, N.4
Good, V.5
Dale, T.C.6
Pearl, L.H.7
-
17
-
-
0025272167
-
Chromosome 9 from independent clones and isolates of Plasmodium falciparum undergoes subtelomeric deletions with similar breakpoints in vitro
-
Shirley M.V., Biggs B.A., Forsyth K.P., Brown H.J., Kemp D.J. Chromosome 9 from independent clones and isolates of Plasmodium falciparum undergoes subtelomeric deletions with similar breakpoints in vitro. Mol. Biochem. Parasitol. 40:1990;137-146.
-
(1990)
Mol. Biochem. Parasitol.
, vol.40
, pp. 137-146
-
-
Shirley, M.V.1
Biggs, B.A.2
Forsyth, K.P.3
Brown, H.J.4
Kemp, D.J.5
-
18
-
-
0018704491
-
Synchronisation of Plasmodium falciparum erythrocytic stages in culture
-
Lambros C., Vanderberg J.P. Synchronisation of Plasmodium falciparum erythrocytic stages in culture. J. Parasitol. 65:1979;418-420.
-
(1979)
J. Parasitol.
, vol.65
, pp. 418-420
-
-
Lambros, C.1
Vanderberg, J.P.2
-
19
-
-
0026580539
-
Baculovirus-mediated expression, characterisation of rat glycogen synthase kinase-3 beta, the mammalian homologues of the Drosophila melanogaster zeste-white 3sgg homeotic gene product
-
Hughes K., Pulverer B.J., Theocharous P., Woodgett J.R. Baculovirus-mediated expression, characterisation of rat glycogen synthase kinase-3 beta, the mammalian homologues of the Drosophila melanogaster zeste-white 3sgg homeotic gene product. Eur. J. Biochem. 203:1992;305-311.
-
(1992)
Eur. J. Biochem.
, vol.203
, pp. 305-311
-
-
Hughes, K.1
Pulverer, B.J.2
Theocharous, P.3
Woodgett, J.R.4
-
20
-
-
0028988027
-
Pfcrk-1, a developmentally regulated cdc2-related protein kinase of Plasmodium falciparum
-
Doerig C.D., Doerig C.M., Horrocks P., Carlton J., Sultan A., Arnot D., Carter R. Pfcrk-1, a developmentally regulated cdc2-related protein kinase of Plasmodium falciparum. Mol. Biochem. Parasitol. 70:1995;167-174.
-
(1995)
Mol. Biochem. Parasitol.
, vol.70
, pp. 167-174
-
-
Doerig, C.D.1
Doerig, C.M.2
Horrocks, P.3
Carlton, J.4
Sultan, A.5
Arnot, D.6
Carter, R.7
-
21
-
-
0017311840
-
Human malaria parasite in continuous culture
-
Trager W.T., Jensen J.B. Human malaria parasite in continuous culture. Science. 193:1976;673-675.
-
(1976)
Science
, vol.193
, pp. 673-675
-
-
Trager, W.T.1
Jensen, J.B.2
-
22
-
-
0018249537
-
Separation of viable schizont-infected cells of Plasmodium falciparum from human blood
-
Pasvol G., Wilson R.J.M., Smalley M.E., Brown J. Separation of viable schizont-infected cells of Plasmodium falciparum from human blood. Ann. Trop. Med. Parasitol. 72:1978;87-88.
-
(1978)
Ann. Trop. Med. Parasitol.
, vol.72
, pp. 87-88
-
-
Pasvol, G.1
Wilson, R.J.M.2
Smalley, M.E.3
Brown, J.4
-
23
-
-
0033527048
-
The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum
-
Bowman S., Lawson D., Basham D., Brown D., Chillingworth T., Churcher C.M., Craig A., Davies R.M., Devlin K., Feltwell T., Gentles S., Gwilliam R., Hamlin N., Harris D., Holroyd S., Hornsby T., Horrocks P., Jagels K., Jassal B., Kyes S., McLean J., Moule S., Mungall K., Murphy L., Barrell B.G. The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum. Nature. 400:1999;532-538.
-
(1999)
Nature
, vol.400
, pp. 532-538
-
-
Bowman, S.1
Lawson, D.2
Basham, D.3
Brown, D.4
Chillingworth, T.5
Churcher, C.M.6
Craig, A.7
Davies, R.M.8
Devlin, K.9
Feltwell, T.10
Gentles, S.11
Gwilliam, R.12
Hamlin, N.13
Harris, D.14
Holroyd, S.15
Hornsby, T.16
Horrocks, P.17
Jagels, K.18
Jassal, B.19
Kyes, S.20
McLean, J.21
Moule, S.22
Mungall, K.23
Murphy, L.24
Barrell, B.G.25
more..
-
24
-
-
0034969088
-
A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation
-
Frame S., Cohen P., Biondi R.M. A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation. Mol. Cell. 7:2001;1321-1327.
-
(2001)
Mol. Cell
, vol.7
, pp. 1321-1327
-
-
Frame, S.1
Cohen, P.2
Biondi, R.M.3
-
25
-
-
0034743516
-
Structure of GSK3β reveals a primed phosphorylation mechanism
-
ter Haar E., Coll J.T., Austen D.A., Hsiao H.M., Swenson L., Jain J. Structure of GSK3β reveals a primed phosphorylation mechanism. Nat. Struct. Biol. 8:2001;593-596.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 593-596
-
-
Ter Haar, E.1
Coll, J.T.2
Austen, D.A.3
Hsiao, H.M.4
Swenson, L.5
Jain, J.6
-
26
-
-
0034718421
-
Regulation, localization of Tyrosine216 phosphorylation of glycogen synthase kinase-3β in cellular and animal models of neuronal degeneration
-
Bhat R.V., Shanley J., Correll M.P., Fieles W.E., Keith R.A., Scott C.W., Lee C.M. Regulation, localization of Tyrosine216 phosphorylation of glycogen synthase kinase-3β in cellular and animal models of neuronal degeneration. Proc. Natl. Acad. Sci. U. S. A. 97:2000;11074-11079.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 11074-11079
-
-
Bhat, R.V.1
Shanley, J.2
Correll, M.P.3
Fieles, W.E.4
Keith, R.A.5
Scott, C.W.6
Lee, C.M.7
-
27
-
-
0032734021
-
The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification
-
Kim L., Liu J., Kimmel A.R. The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification. Cell. 99:1999;399-408.
-
(1999)
Cell
, vol.99
, pp. 399-408
-
-
Kim, L.1
Liu, J.2
Kimmel, A.R.3
-
28
-
-
0032955426
-
Insulin transiently increases tau phosphorylation: Involvement of glycogen synthase kinase-3beta, Fyn tyrosine kinase
-
Lesort M., Jope R.S., Johnson G.V. Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta, Fyn tyrosine kinase. J. Neurochem. 72:1999;576-584.
-
(1999)
J. Neurochem.
, vol.72
, pp. 576-584
-
-
Lesort, M.1
Jope, R.S.2
Johnson, G.V.3
-
29
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross D.A., Alessi D.R., Cohen P., Andjelkovich M., Hemmings B.A. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature. 378:1995;785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
30
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
Dudek H., Datta S.R., Franke T.F., Birnbaum M.J., Yao R.J., Cooper G.M., Segal R.A., Kaplan D.R., Greenberg M.E. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science. 275:1997;661-665.
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.J.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
31
-
-
0030907987
-
PI3K: Downstream AKTion blocks apoptosis
-
Franke T.F., Kaplan D.R., Cantley L.C. PI3K: downstream AKTion blocks apoptosis. Cell. 88:1997;435-437.
-
(1997)
Cell
, vol.88
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
32
-
-
12944250922
-
Phosphorylation, inactivation of glycogen synthase kinase 3 by protein kinase a
-
Fang X., Yu S.X., Lu Y., Bast R.C., Woodgett J.R., Mills G.B. Phosphorylation, inactivation of glycogen synthase kinase 3 by protein kinase A. Proc. Natl. Acad. Sci. U. S. A. 97:2000;11960-11965.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 11960-11965
-
-
Fang, X.1
Yu, S.X.2
Lu, Y.3
Bast, R.C.4
Woodgett, J.R.5
Mills, G.B.6
-
33
-
-
0037127255
-
Identification of the Axin, FRAT/GBP binding region of glycogen synthase kinase-3
-
Fraser E., Young N., Dajani R., Franca-Koh J., Ryves J., Williams R.S., Yeo M., Webster M.T., Richardson C., Smalley M.J., Pearl L.H., Harwood A., Dale T.C. Identification of the Axin, FRAT/GBP binding region of glycogen synthase kinase-3. J. Biol. Chem. 277:2001;2176-2185.
-
(2001)
J. Biol. Chem.
, vol.277
, pp. 2176-2185
-
-
Fraser, E.1
Young, N.2
Dajani, R.3
Franca-Koh, J.4
Ryves, J.5
Williams, R.S.6
Yeo, M.7
Webster, M.T.8
Richardson, C.9
Smalley, M.J.10
Pearl, L.H.11
Harwood, A.12
Dale, T.C.13
-
34
-
-
0037067733
-
Intracellular targets of paullones: Identification by affinity chromatography using immobilized inhibitor
-
Knockaert M., Viking K., Schmitt S., Leost M., Mottram J., Kunick C., Meijer L. Intracellular targets of paullones: identification by affinity chromatography using immobilized inhibitor. J. Biol. Chem. 277:2002;25493-25501.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25493-25501
-
-
Knockaert, M.1
Viking, K.2
Schmitt, S.3
Leost, M.4
Mottram, J.5
Kunick, C.6
Meijer, L.7
-
35
-
-
0030449964
-
Lithium inhibits glycogen synthase kinase-3 activity, mimics Wingless signaling in intact cells
-
Stambolic V., Ruel L., Woodgett J.R. Lithium inhibits glycogen synthase kinase-3 activity, mimics Wingless signaling in intact cells. Curr. Biol. 6:1996;1664-1668.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1664-1668
-
-
Stambolic, V.1
Ruel, L.2
Woodgett, J.R.3
-
36
-
-
0030868557
-
Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3
-
Hong M., Chen D.C., Klein P.S., Lee V.M. Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3. J. Biol. Chem. 272:1997;25326-25332.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25326-25332
-
-
Hong, M.1
Chen, D.C.2
Klein, P.S.3
Lee, V.M.4
-
37
-
-
0034805180
-
Lithium inhibits glycogen synthase kinase-3 by competition for magnesium
-
Ryves W.J., Harwood A.J. Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem. Biophys. Res. Commun. 280:2001;720-725.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 720-725
-
-
Ryves, W.J.1
Harwood, A.J.2
-
38
-
-
0034010742
-
Inhibition of cyclin-dependent kinases 1, 2, 5, GSK-3β and CK1 by hymenialdisine, a marine sponge constituent
-
Meijer L., Thunissen A.-M.W.H., White A., Garnier M., Nikolic M., Tsai L.H., Walter J., Cleverley K.E., Salinas P.C., Wu Y.Z., Biernat J., Mandelkow E.M., Kim S.-H., Pettit G.R. Inhibition of cyclin-dependent kinases 1, 2, 5, GSK-3β and CK1 by hymenialdisine, a marine sponge constituent. Chem. Biol. 7:2000;51-63.
-
(2000)
Chem. Biol.
, vol.7
, pp. 51-63
-
-
Meijer, L.1
Thunissen, A.-M.W.H.2
White, A.3
Garnier, M.4
Nikolic, M.5
Tsai, L.H.6
Walter, J.7
Cleverley, K.E.8
Salinas, P.C.9
Wu, Y.Z.10
Biernat, J.11
Mandelkow, E.M.12
Kim, S.-H.13
Pettit, G.R.14
-
39
-
-
0033798031
-
Paullones are potent inhibitors of glycogen synthase kinase-3β and cyclin-dependent kinase 5/p25
-
Leost M., Schultz C., Link A., Wu Y.-Z., Biernat J., Mandelkow E.-M., Bibb J.A., Snyder G.L., Greengard P., Zaharevitz D.W., Gussio R., Senderovitz A., Sausville E.A., Kunick C., Meijer L. Paullones are potent inhibitors of glycogen synthase kinase-3β and cyclin-dependent kinase 5/p25. Eur. J. Biochem. 267:2000;5983-5994.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 5983-5994
-
-
Leost, M.1
Schultz, C.2
Link, A.3
Wu, Y.-Z.4
Biernat, J.5
Mandelkow, E.-M.6
Bibb, J.A.7
Snyder, G.L.8
Greengard, P.9
Zaharevitz, D.W.10
Gussio, R.11
Senderovitz, A.12
Sausville, E.A.13
Kunick, C.14
Meijer, L.15
-
40
-
-
0033776383
-
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
-
Coghlan M.P., Culbert A.A., Cross D.A.E., Corcoran S.L., Yates J.W., Pearce N.J., Rausch O.L., Murphy G.J., Carter P.S., Cox L.R., Mills D., Brown M.J., Haigh D., Ward R.W., Smith D.G., Murray K.J., Reith A.D., Holder J.C. Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription. Chem. Biol. 7:2000;793-803.
-
(2000)
Chem. Biol.
, vol.7
, pp. 793-803
-
-
Coghlan, M.P.1
Culbert, A.A.2
Cross, D.A.E.3
Corcoran, S.L.4
Yates, J.W.5
Pearce, N.J.6
Rausch, O.L.7
Murphy, G.J.8
Carter, P.S.9
Cox, L.R.10
Mills, D.11
Brown, M.J.12
Haigh, D.13
Ward, R.W.14
Smith, D.G.15
Murray, K.J.16
Reith, A.D.17
Holder, J.C.18
-
41
-
-
0035848403
-
3-Anilino-4-arylmaleimides: Potent, selective inhibitors of glycogen synthase kinase-3 (GSK-3)
-
Smith D.G., Buffet M., Fenwick A.E., Haigh D., Ife R.J., Saunders M., Slingsby B.P., Stacey R., Ward R.W. 3-Anilino-4-arylmaleimides: potent, selective inhibitors of glycogen synthase kinase-3 (GSK-3). Bioorg. Med. Chem. Lett. 11:2001;635-639.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 635-639
-
-
Smith, D.G.1
Buffet, M.2
Fenwick, A.E.3
Haigh, D.4
Ife, R.J.5
Saunders, M.6
Slingsby, B.P.7
Stacey, R.8
Ward, R.W.9
-
42
-
-
0035808457
-
Indirubins inhibit glycogen synthase kinase- 3β, CDK5/p25, two kinases involved in abnormal tau phosphorylation in Alzheimer's disease- a property common to most CDK inhibitors?
-
Leclerc S., Garnier M., Hoessel R., Marko D., Bibb J.A., Snyder G.L., Greengard P., Biernat J., Mandelkow E.-M., Eisenbrand G., Meijer L. Indirubins inhibit glycogen synthase kinase- 3β, CDK5/p25, two kinases involved in abnormal tau phosphorylation in Alzheimer's disease- A property common to most CDK inhibitors? J. Biol. Chem. 276:2001;251-260.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 251-260
-
-
Leclerc, S.1
Garnier, M.2
Hoessel, R.3
Marko, D.4
Bibb, J.A.5
Snyder, G.L.6
Greengard, P.7
Biernat, J.8
Mandelkow, E.-M.9
Eisenbrand, G.10
Meijer, L.11
-
43
-
-
0028093182
-
Inhibition of cyclin-dependent kinases by purine derivatives
-
Vesely J., Havlicek L., Strnad M., Blow J.J., Donella-Deana A., Pinna L., Letham D.S., Kato J.Y., Détivaud L., Leclerc S., Meijer L. Inhibition of cyclin-dependent kinases by purine derivatives. Eur. J. Biochem. 224:1994;771-786.
-
(1994)
Eur. J. Biochem.
, vol.224
, pp. 771-786
-
-
Vesely, J.1
Havlicek, L.2
Strnad, M.3
Blow, J.J.4
Donella-Deana, A.5
Pinna, L.6
Letham, D.S.7
Kato, J.Y.8
Détivaud, L.9
Leclerc, S.10
Meijer, L.11
-
44
-
-
0031037714
-
Biochemical, cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2, cdk5
-
Meijer L., Borgne A., Mulner O., Chong J.P.J., Blow J.J., Inagaki N., Inagaki M., Delcros J.G., Moulinoux J.P. Biochemical, cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2, cdk5. Eur. J. Biochem. 243:1997;527-536.
-
(1997)
Eur. J. Biochem.
, vol.243
, pp. 527-536
-
-
Meijer, L.1
Borgne, A.2
Mulner, O.3
Chong, J.P.J.4
Blow, J.J.5
Inagaki, N.6
Inagaki, M.7
Delcros, J.G.8
Moulinoux, J.P.9
-
45
-
-
0032563315
-
Exploiting chemical libraries, structure, and genomics in the search for new kinase inhibitors
-
Gray N., Wodicka L., Thunnissen A.M., Norman T., Kwon S., Espinoza F.H., Morgan D.O., Barnes G., Leclerc S., Meijer L., Kim S.H., Lockhart D.J., Schultze P. Exploiting chemical libraries, structure, and genomics in the search for new kinase inhibitors. Science. 281:1998;533-538.
-
(1998)
Science
, vol.281
, pp. 533-538
-
-
Gray, N.1
Wodicka, L.2
Thunnissen, A.M.3
Norman, T.4
Kwon, S.5
Espinoza, F.H.6
Morgan, D.O.7
Barnes, G.8
Leclerc, S.9
Meijer, L.10
Kim, S.H.11
Lockhart, D.J.12
Schultze, P.13
-
46
-
-
0023475545
-
Plasmodium berghei, P chabaudi, and P falciparum: Similarities in phosphoproteins and protein kinase activities and their stage specific expression
-
Wiser M.F., Plitt B. Plasmodium berghei, P chabaudi, and P falciparum: similarities in phosphoproteins and protein kinase activities and their stage specific expression. Exp. Parasitol. 64:1987;328-335.
-
(1987)
Exp. Parasitol.
, vol.64
, pp. 328-335
-
-
Wiser, M.F.1
Plitt, B.2
-
47
-
-
0025300514
-
Protein phosphorylation during the asexual life cycle of the human malarial Plasmodium falciparum
-
Jones G.L., McLemore Edmundson H. Protein phosphorylation during the asexual life cycle of the human malarial Plasmodium falciparum. Biochim. Biophys. Acta. 1053:1990;118-124.
-
(1990)
Biochim. Biophys. Acta
, vol.1053
, pp. 118-124
-
-
Jones, G.L.1
McLemore Edmundson, H.2
-
48
-
-
0024521681
-
Phosphorylation of erythrocyte membrane and cytoskeleton proteins in cells infected with Plasmodium falciparum
-
Murray M.C., Perkins M.E. Phosphorylation of erythrocyte membrane and cytoskeleton proteins in cells infected with Plasmodium falciparum. Mol. Biochem. Parasitol. 34:1989;229-236.
-
(1989)
Mol. Biochem. Parasitol.
, vol.34
, pp. 229-236
-
-
Murray, M.C.1
Perkins, M.E.2
-
49
-
-
0026739575
-
Regulation and post-translational modification of erythrocyte membrane, membrane-skeletal proteins
-
Cohen C.M., Gascard P. Regulation and post-translational modification of erythrocyte membrane, membrane-skeletal proteins. Semin. Hematol. 29:1992;244-292.
-
(1992)
Semin. Hematol.
, vol.29
, pp. 244-292
-
-
Cohen, C.M.1
Gascard, P.2
-
50
-
-
0028307510
-
Phosphorylation of protein 41 in Plasmodium falciparum-infected human red blood cells
-
Chisti A.H., Maalouf G.J., Marfatia S., Palek J., Wang W., Fisher D., Liu S.C. Phosphorylation of protein 41 in Plasmodium falciparum-infected human red blood cells. Blood. 83:1994;3339-3345.
-
(1994)
Blood
, vol.83
, pp. 3339-3345
-
-
Chisti, A.H.1
Maalouf, G.J.2
Marfatia, S.3
Palek, J.4
Wang, W.5
Fisher, D.6
Liu, S.C.7
-
51
-
-
0030839074
-
Signal transduction in malaria parasites
-
Doerig C.D. Signal transduction in malaria parasites. Parasitol. Today. 13:1997;307-312.
-
(1997)
Parasitol. Today
, vol.13
, pp. 307-312
-
-
Doerig, C.D.1
-
53
-
-
0032054251
-
Characterisation of PfSec61, a Plasmodium falciparum homologue of the translocation machinery at the endoplasmic reticulum membrane of eukaryotic cells
-
Couffin S., Hernandez-Rivas R., Blisnick T., Mattei D. Characterisation of PfSec61, a Plasmodium falciparum homologue of the translocation machinery at the endoplasmic reticulum membrane of eukaryotic cells. Mol. Biochem. Parasitol. 92:1998;89-98.
-
(1998)
Mol. Biochem. Parasitol.
, vol.92
, pp. 89-98
-
-
Couffin, S.1
Hernandez-Rivas, R.2
Blisnick, T.3
Mattei, D.4
-
54
-
-
0025204355
-
Ultrastructure of malaria-infected erythrocytes
-
Atkinson C.T., Aikawa M. Ultrastructure of malaria-infected erythrocytes. Blood Cells. 16:1990;351-368.
-
(1990)
Blood Cells
, vol.16
, pp. 351-368
-
-
Atkinson, C.T.1
Aikawa, M.2
-
55
-
-
0033758215
-
Pfsbp1, a Maurer's cleft Plasmodium falciparum protein, is associated with the erythrocyte skeleton
-
Blisnick T., Betoulle M.E.M., Barale J.-C., Uzureau P., Berry L., Desroses S., Fujioka H., Mattei D., Breton C.B. Pfsbp1, a Maurer's cleft Plasmodium falciparum protein, is associated with the erythrocyte skeleton. Mol. Biochem. Parasitol. 111:2000;107-121.
-
(2000)
Mol. Biochem. Parasitol.
, vol.111
, pp. 107-121
-
-
Blisnick, T.1
Betoulle, M.E.M.2
Barale, J.-C.3
Uzureau, P.4
Berry, L.5
Desroses, S.6
Fujioka, H.7
Mattei, D.8
Breton, C.B.9
-
56
-
-
0024445506
-
A new blood stage antigen of Plasmodium falciparum transported to the erythrocyte surface
-
Knapp B., Hundt E., Küpper H.A. A new blood stage antigen of Plasmodium falciparum transported to the erythrocyte surface. Mol. Biochem. Parasitol. 37:1989;47-56.
-
(1989)
Mol. Biochem. Parasitol.
, vol.37
, pp. 47-56
-
-
Knapp, B.1
Hundt, E.2
Küpper, H.A.3
-
57
-
-
0023441057
-
Structure and expression of the knob-associated histidine-rich protein of Plasmodium falciparum
-
Ellis J., Irving D.O., Wellems T.E., Howard R.J., Cross G.A. Structure and expression of the knob-associated histidine-rich protein of Plasmodium falciparum. Mol. Biochem. Parasitol. 26:1987;203-214.
-
(1987)
Mol. Biochem. Parasitol.
, vol.26
, pp. 203-214
-
-
Ellis, J.1
Irving, D.O.2
Wellems, T.E.3
Howard, R.J.4
Cross, G.A.5
-
58
-
-
0035886970
-
Trafficking and assembly of the cytoadherence complex in Plasmodium falciparum-infected human erythrocytes
-
Wickham M.E., Rug M., Ralph S.A., Klonis N., McFadden G.I., Tilley L., Cowman A.F. Trafficking and assembly of the cytoadherence complex in Plasmodium falciparum-infected human erythrocytes. EMBO J. 20:2001;5636-5649.
-
(2001)
EMBO J.
, vol.20
, pp. 5636-5649
-
-
Wickham, M.E.1
Rug, M.2
Ralph, S.A.3
Klonis, N.4
McFadden, G.I.5
Tilley, L.6
Cowman, A.F.7
-
59
-
-
0035069258
-
Membrane transport in the malaria-infected erythrocyte
-
Kirk K. Membrane transport in the malaria-infected erythrocyte. Physiol. Rev. 81:2001;495-537.
-
(2001)
Physiol. Rev.
, vol.81
, pp. 495-537
-
-
Kirk, K.1
-
60
-
-
0023574139
-
Ultrastructural localization of erythrocyte cytoskeletal and integral membrane proteins in Plasmodium falciparum-infected erythrocytes
-
Atkinson C.T., Aikawa M., Perry G., Fujino T., Bennett V., Davidson E.A., Howard R.J. Ultrastructural localization of erythrocyte cytoskeletal and integral membrane proteins in Plasmodium falciparum-infected erythrocytes. Eur. J. Cell Biol. 45:1987;192-199.
-
(1987)
Eur. J. Cell Biol.
, vol.45
, pp. 192-199
-
-
Atkinson, C.T.1
Aikawa, M.2
Perry, G.3
Fujino, T.4
Bennett, V.5
Davidson, E.A.6
Howard, R.J.7
-
61
-
-
0034739003
-
A voltage-dependent channel involved in nutrient uptake by red blood cells infected with the malaria parasite
-
Desai S.A., Bezrukov S.M., Zimmerberg J. A voltage-dependent channel involved in nutrient uptake by red blood cells infected with the malaria parasite. Nature. 406:2000;1001-1005.
-
(2000)
Nature
, vol.406
, pp. 1001-1005
-
-
Desai, S.A.1
Bezrukov, S.M.2
Zimmerberg, J.3
-
62
-
-
0035968076
-
Malaria parasite Plasmodium gallinaceum up-regulates host red blood cell channels
-
Thomas S.L., Egee S., Lapaix F., Kaestner L., Staines H.M., Ellory J.C. Malaria parasite Plasmodium gallinaceum up-regulates host red blood cell channels. FEBS Lett. 500:2001;45-51.
-
(2001)
FEBS Lett.
, vol.500
, pp. 45-51
-
-
Thomas, S.L.1
Egee, S.2
Lapaix, F.3
Kaestner, L.4
Staines, H.M.5
Ellory, J.C.6
-
63
-
-
0033780574
-
Calcium-dependent modulation by melatonin of the circadian rhythm in malarial parasites
-
Hotta C.T., Gazarini M.L., Beraldo F.H., Varotti F.P., Lopes C., Markus R.P., Pozzan T., Garcia C.R. Calcium-dependent modulation by melatonin of the circadian rhythm in malarial parasites. Nat. Cell Biol. 2:2002;466-468.
-
(2002)
Nat. Cell Biol.
, vol.2
, pp. 466-468
-
-
Hotta, C.T.1
Gazarini, M.L.2
Beraldo, F.H.3
Varotti, F.P.4
Lopes, C.5
Markus, R.P.6
Pozzan, T.7
Garcia, C.R.8
-
64
-
-
0035875069
-
A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock
-
Martinek S., Inonog S., Manoukian A.S., Young M.W. A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock. Cell. 105:2001;769-779.
-
(2001)
Cell
, vol.105
, pp. 769-779
-
-
Martinek, S.1
Inonog, S.2
Manoukian, A.S.3
Young, M.W.4
-
65
-
-
0035458732
-
Time zones: A comparative genetics of circadian clocks
-
Young M.W., Kay S.A. Time zones: a comparative genetics of circadian clocks. Nat. Rev., Genet. 2:2001;702-715.
-
(2001)
Nat. Rev., Genet.
, vol.2
, pp. 702-715
-
-
Young, M.W.1
Kay, S.A.2
-
66
-
-
0030705190
-
Identification, cloning, mutational analysis of the casein kinase 1 cDNA of the malaria parasite, Plasmodium falciparum
-
Barik S., Taylor R.E., Chakrabarti D. Identification, cloning, mutational analysis of the casein kinase 1 cDNA of the malaria parasite, Plasmodium falciparum. J. Biol. Chem. 272:1997;26132-26138.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26132-26138
-
-
Barik, S.1
Taylor, R.E.2
Chakrabarti, D.3
-
67
-
-
0034086397
-
Intracellular targets of cyclin-dependent kinase inhibitors: Identification by affinity chromatography using immobilised ligants
-
Knockaert M., Gray N., Damiens E., Chang Y.T., Grellier P., Grant K., Fergusson D., Mottram J., Soete M., Dubremetz J.F., LeRoch K., Doerig C., Schultz P.G., Meijer L. Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised ligants. Chem. Biol. 7:2000;411-422.
-
(2000)
Chem. Biol.
, vol.7
, pp. 411-422
-
-
Knockaert, M.1
Gray, N.2
Damiens, E.3
Chang, Y.T.4
Grellier, P.5
Grant, K.6
Fergusson, D.7
Mottram, J.8
Soete, M.9
Dubremetz, J.F.10
Leroch, K.11
Doerig, C.12
Schultz, P.G.13
Meijer, L.14
-
69
-
-
0026244229
-
MOLSCRIPT-a program to produce both detailed and schematic plots of protein structures
-
Kraulis P.J. MOLSCRIPT-a program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24:1991;946-950.
-
(1991)
J. Appl. Crystallogr.
, vol.24
, pp. 946-950
-
-
Kraulis, P.J.1
-
70
-
-
0028057108
-
Raster3D version 20-a program for photorealistic molecular graphics
-
Merrit E.A., Murphy M.E.P. Raster3D version 20-a program for photorealistic molecular graphics. Acta Crystallogr. 50:1994;869-873.
-
(1994)
Acta Crystallogr.
, vol.50
, pp. 869-873
-
-
Merrit, E.A.1
Murphy, M.E.P.2
-
71
-
-
0026319199
-
Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
-
Nicholls A., Sharp K., Honig B. Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins, Struct., Funct. Genet. 11:1991;281-296.
-
(1991)
Proteins, Struct., Funct. Genet.
, vol.11
, pp. 281-296
-
-
Nicholls, A.1
Sharp, K.2
Honig, B.3
|