Novel cytotoxic brominated diterpenes from the red alga Laurencia obtusa

Journal of Organic Chemistry

Volumn 68, Issue 20, 2003, Pages 7667-7674

  Iliopoulou, Dimitra ^a   Mihopoulos, Nikos ^b   Vagias, Constantinos ^a   Papazafiri, Panagiota ^a   Roussis, Vassilios ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b TECHNOLOGICAL EDUCATIONAL INSTITUTE OF CRETE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; COASTAL ZONES; ROCKS; SPECTRUM ANALYSIS; STEREOCHEMISTRY;

DITERPENES;

AROMATIC HYDROCARBONS;

CYTOTOXIC AGENT; DITERPENE; NATURAL PRODUCT; PREVEZOL B; PREVEZOL C; PREVEZOL D; PREVEZOL E; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; RED ALGA; SPECTROSCOPY; STEREOCHEMISTRY;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; HYDROCARBONS, BROMINATED; INHIBITORY CONCENTRATION 50; LAURENCIA; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;

EID: 0141432024     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0342323     Document Type: Article

References (15)

1. Faulkner, D. J. Nat. Prod. Rep. 2002, 19, 1-48.
2. Norte, M.; Gonzalez, A. G.; Cataldo, F.; Rodriguez, M. L.; Brito, I. Tetrahedron 1991, 47, 9411-9418.
3. König, G. M.; Wright, A. D. J. Nat. Prod. 1994, 57, 477-485.
4. Iliopoulou, D.; Vagias, C.; Harvala, C.; Roussis, V. Phytochemistry 2002, 59, 111-116.
5. Guella, G.; Pietra, F. Helv. Chim. Acta 2000, 83, 2946-2952.
6. Guella, G.; Marchetti, F.; Pietra, F. Helv. Chim. Acta 1997, 80, 684-694.
7. Mihopoulos, N.; Vagias, C.; Mikros, E.; Scoullos, M.; Roussis, V. Tetrahedron Lett. 2001, 42, 3749-3752.
8. Amico, V.; Caccamese, S.; Neri, P.; Russo, G.; Foti, M. Phytochemistry 1991, 30, 1921-1927.
9. Wright, A. D.; König, G. M.; Sticher, O. J. Nat. Prod. 1991, 54, 1025-1033.
10. Brito, I.; Mercedes, C.; Diaz-Marrero, A. R.; Darias, J.; San Martin, A. J. Nat. Prod. 2002, 65, 946-948.
11. Iliopoulou, D.; Roussis,V.; Pannecouque, C.; De Clercq, E.; Vagias, C. Tetrahedron 2002, 58, 6749-6755.
12. Iliopoulou, D.; Vagias,C.; Galanakis, D.; Argyropoulos, D.; Roussis, V. Org. Lett. 2002, 4, 3263-3266.
13. Erickson, K. L. In Marine Natural Products: Chemical and Biological Perspectives; Scheuer, P. J., Ed.; Academic Press: New York, 1983; Vol. V, pp 131-257.
14. Mossmann, T. J. Immunol. Methods 1983, 139, 55-63.
15. Alley, M. C.; Scudiero, A. D.; Monks, A.; Hursey, M. L.; Czerwinski, M. J.; Fine, D. L.; Abbott, B. J. Cancer Res. 1988, 48, 589-601.