Gα12 directly interacts with PP2A: Evidence for Gα12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau

Journal of Biological Chemistry

Volumn 279, Issue 53, 2004, Pages 54983-54986

  Zhu, Deguang ^a   Kosik, Kenneth S ^b   Meigs, Thomas E ^c   Yanamadala, Vijay ^a   Denker, Bradley M ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF NORTH CAROLINA AT ASHEVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; ENZYME INHIBITION; IMMUNOLOGY; PRECIPITATION (CHEMICAL); PROTEINS; YEAST;

COIMMUNOPRECIPITATION; MULTIPLE CELLULAR PROCESSES; OKADAIC ACID; PHOSPHORYLATION;

ENZYME KINETICS;

A ALPHA PROTEIN; ACTIN; CYCLIN DEPENDENT KINASE 5; G ALPHA 13 PROTEIN; G ALPHA12 PROTEIN; GLUTATHIONE TRANSFERASE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; OKADAIC ACID; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN; PROTEIN KINASE; PROTEIN P25; SCAFFOLD PROTEIN; SERINE THREONINE PHOSPHATASE; TAU PROTEIN; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; LIGAND; PHOSPHOPROTEIN PHOSPHATASE; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CELL LYSATE; CELL STRAIN CACO 2; CELL STRAIN COS1; CONTROLLED STUDY; CYTOSKELETON; DEPHOSPHORYLATION; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; NERVE CELL; NEUROFIBRILLARY TANGLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; ANIMAL; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; METABOLISM; PHOSPHORYLATION; PROTEIN BINDING; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TWO HYBRID SYSTEM; WESTERN BLOTTING;

ANIMALIA;

ACTINS; ANIMALS; BLOTTING, WESTERN; CACO-2 CELLS; COS CELLS; CYTOSKELETON; DNA, COMPLEMENTARY; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LIGANDS; MICROSCOPY, FLUORESCENCE; NEURONS; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TAU PROTEINS; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 11244315157     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C400508200     Document Type: Article

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