메뉴 건너뛰기




Volumn 22, Issue 16, 2002, Pages 6863-6875

Glycogen synthase kinase-3 is activated in neuronal cells by Gα12 and Gα13 by Rho-independent and Rho-dependent mechanisms

Author keywords

GSK 3 activation; G 12 13; Lysophosphatidic acid; Neurite retraction; RhoA; Tau hyperphosphorylation

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3; LITHIUM; LYSOPHOSPHATIDIC ACID; PHOSPHOLIPASE C; RHO FACTOR; TAU PROTEIN;

EID: 0037104720     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-16-06863.2002     Document Type: Article
Times cited : (76)

References (57)
  • 1
    • 0034718421 scopus 로고    scopus 로고
    • Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration
    • Bhat RV, Shanley J, Correll MP, Fieles WE, Keith RA, Scott CW, Lee CM (2000) Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration. Proc Natl Acad Sci USA 97:11074-11079.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 11074-11079
    • Bhat, R.V.1    Shanley, J.2    Correll, M.P.3    Fieles, W.E.4    Keith, R.A.5    Scott, C.W.6    Lee, C.M.7
  • 2
    • 0035906267 scopus 로고    scopus 로고
    • The mouse 1p(A3)/Edg7 lysophosphatidic acid receptor gene: Genomic structure, chromosomal localization, and expression pattern
    • Contos JJ, Chun J (2001) The mouse 1p(A3)/Edg7 lysophosphatidic acid receptor gene: Genomic structure, chromosomal localization, and expression pattern. Gene 267:243-253.
    • (2001) Gene , vol.267 , pp. 243-253
    • Contos, J.J.1    Chun, J.2
  • 3
    • 0033669622 scopus 로고    scopus 로고
    • Lysophosphatidic acid receptors
    • Contos JJ, Ishii I, Chun J (2000) Lysophosphatidic acid receptors. Mol Pharmacol 58:1188-1196.
    • (2000) Mol Pharmacol , vol.58 , pp. 1188-1196
    • Contos, J.J.1    Ishii, I.2    Chun, J.3
  • 4
    • 0029811434 scopus 로고    scopus 로고
    • Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a PKC
    • Cook D, Fry MJ, Hughes K, Sumathipala R, Woodgett JR, Dale TC (1996) Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a PKC. EMBO J 15:4526-4536.
    • (1996) EMBO J , vol.15 , pp. 4526-4536
    • Cook, D.1    Fry, M.J.2    Hughes, K.3    Sumathipala, R.4    Woodgett, J.R.5    Dale, T.C.6
  • 5
    • 0035219781 scopus 로고    scopus 로고
    • Assays for glycogen synthase kinase-3 (GSK-3)
    • Cross D (2001) Assays for glycogen synthase kinase-3 (GSK-3). Methods Mol Biol 124:147-159.
    • (2001) Methods Mol Biol , vol.124 , pp. 147-159
    • Cross, D.1
  • 6
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA (1995) Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378:785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 7
    • 0034602179 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal
    • Crowder RJ, Freeman RS (2000) Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal. J Biol Chem 275:34266-34271.
    • (2000) J Biol Chem , vol.275 , pp. 34266-34271
    • Crowder, R.J.1    Freeman, R.S.2
  • 8
    • 0032530482 scopus 로고    scopus 로고
    • Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
    • Delcommenne M, Tan C, Gray V, Rue L, Woodgett J, Dedhar S (1998) Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc Natl Acad Sci USA 95:11211-11216.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11211-11216
    • Delcommenne, M.1    Tan, C.2    Gray, V.3    Rue, L.4    Woodgett, J.5    Dedhar, S.6
  • 9
    • 0033553216 scopus 로고    scopus 로고
    • Identification of Gα13 as one of the G-proteins that couple to human platelet thromboxane A2 receptors
    • Djellas Y, Manganello JM, Antonakis K, Le Breton GC (1999) Identification of Gα13 as one of the G-proteins that couple to human platelet thromboxane A2 receptors. J Biol Chem 274:14325-14330.
    • (1999) J Biol Chem , vol.274 , pp. 14325-14330
    • Djellas, Y.1    Manganello, J.M.2    Antonakis, K.3    Le Breton, G.C.4
  • 11
    • 0034665645 scopus 로고    scopus 로고
    • GSK-3: New thoughts on an old enzyme
    • Ferkey DM, Kimelman D (2000) GSK-3: New thoughts on an old enzyme. Dev Biol 225:471-479.
    • (2000) Dev Biol , vol.225 , pp. 471-479
    • Ferkey, D.M.1    Kimelman, D.2
  • 12
    • 0034551689 scopus 로고    scopus 로고
    • Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology
    • Fukushima N, Weiner JA, Chun J (2000) Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology. Dev Biol 228:6-18.
    • (2000) Dev Biol , vol.228 , pp. 6-18
    • Fukushima, N.1    Weiner, J.A.2    Chun, J.3
  • 13
    • 0027420369 scopus 로고
    • Tau protein and the neurofibrillary pathology of Alzheimer's disease
    • Goedert M (1993) tau protein and the neurofibrillary pathology of Alzheimer's disease. Trends Neurosci 16:460-465.
    • (1993) Trends Neurosci , vol.16 , pp. 460-465
    • Goedert, M.1
  • 14
    • 0032548503 scopus 로고    scopus 로고
    • The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho
    • Gohla A, Harhammer R, Schultz G (1998) The G-protein G13 but not G12 mediates signaling from lysophosphatidic acid receptor via epidermal growth factor receptor to Rho. J Biol Chem 273:4653-4659.
    • (1998) J Biol Chem , vol.273 , pp. 4653-4659
    • Gohla, A.1    Harhammer, R.2    Schultz, G.3
  • 15
    • 0033580697 scopus 로고    scopus 로고
    • Differential involvement of Gα12 and Gα13 in receptor-mediated stress fiber formation
    • Gohla A, Offermanns S, Wilkie TM, Schultz G (1999) Differential involvement of Gα12 and Gα13 in receptor-mediated stress fiber formation. J Biol Chem 274:17901-17907.
    • (1999) J Biol Chem , vol.274 , pp. 17901-17907
    • Gohla, A.1    Offermanns, S.2    Wilkie, T.M.3    Schultz, G.4
  • 16
    • 0032748099 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones
    • Goold RG, Owen R, Gordon-Weeks PR (1999) Glycogen synthase kinase 3beta phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones. J Cell Sci 112:3373-3384.
    • (1999) J Cell Sci , vol.112 , pp. 3373-3384
    • Goold, R.G.1    Owen, R.2    Gordon-Weeks, P.R.3
  • 17
    • 0034598921 scopus 로고    scopus 로고
    • Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling
    • Hall AC, Lucas FR, Salinas PC (2000) Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling. Cell 100:525-535.
    • (2000) Cell , vol.100 , pp. 525-535
    • Hall, A.C.1    Lucas, F.R.2    Salinas, P.C.3
  • 18
    • 0026487365 scopus 로고
    • Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase
    • Hanger DP, Hughes K, Woodgett JR, Brion JP, Anderton BH (1992) Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci Lett 147:58-62.
    • (1992) Neurosci Lett , vol.147 , pp. 58-62
    • Hanger, D.P.1    Hughes, K.2    Woodgett, J.R.3    Brion, J.P.4    Anderton, B.H.5
  • 19
    • 0033597936 scopus 로고    scopus 로고
    • Transient increases in intracellular calcium result in prolonged site-selective increases in tau phosphorylation through a glycogen synthase kinase 3beta-dependent pathway
    • Hartigan JA, Johnson GV (1999) Transient increases in intracellular calcium result in prolonged site-selective increases in tau phosphorylation through a glycogen synthase kinase 3beta-dependent pathway. J Biol Chem 274:21395-21401.
    • (1999) J Biol Chem , vol.274 , pp. 21395-21401
    • Hartigan, J.A.1    Johnson, G.V.2
  • 20
  • 21
    • 0029836932 scopus 로고    scopus 로고
    • Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex
    • Hecht JH, Weiner JA, Post SR, Chun J (1996) Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. J Cell Biol 135:1071-1083.
    • (1996) J Cell Biol , vol.135 , pp. 1071-1083
    • Hecht, J.H.1    Weiner, J.A.2    Post, S.R.3    Chun, J.4
  • 22
    • 0027475421 scopus 로고
    • Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation
    • Hughes K, Nikolakaki E, Plyte SE, Totty NF, Woodgett JR (1993) Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation. EMBO J 12:803-808.
    • (1993) EMBO J , vol.12 , pp. 803-808
    • Hughes, K.1    Nikolakaki, E.2    Plyte, S.E.3    Totty, N.F.4    Woodgett, J.R.5
  • 23
    • 0027583540 scopus 로고
    • Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: Similarity to thrombin action
    • Jalink K, Eichholtz T, Postma FR, van Corven EJ, Moolenaar WH (1993) Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: Similarity to thrombin action. Cell Growth Differ 4:247-255.
    • (1993) Cell Growth Differ , vol.4 , pp. 247-255
    • Jalink, K.1    Eichholtz, T.2    Postma, F.R.3    Van Corven, E.J.4    Moolenaar, W.H.5
  • 24
    • 0032582343 scopus 로고    scopus 로고
    • Constitutively active Gα12, Gα13, and Gαq induce Rho-dependent neurite retraction through different signaling pathways
    • Katoh H, Aoki J, Yamaguchi Y, Kitano Y, Ichikawa A, Negishi M (1998) Constitutively active Gα12, Gα13, and Gαq induce Rho-dependent neurite retraction through different signaling pathways. J Biol Chem 273:28700-28707.
    • (1998) J Biol Chem , vol.273 , pp. 28700-28707
    • Katoh, H.1    Aoki, J.2    Yamaguchi, Y.3    Kitano, Y.4    Ichikawa, A.5    Negishi, M.6
  • 25
    • 0032734021 scopus 로고    scopus 로고
    • The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification
    • Kim L, Liu J, Kimmel AR (1999) The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification. Cell 99:399-408.
    • (1999) Cell , vol.99 , pp. 399-408
    • Kim, L.1    Liu, J.2    Kimmel, A.R.3
  • 26
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein PS, Melton DA (1996) A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci USA 93:8455-8459.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 27
    • 0033018626 scopus 로고    scopus 로고
    • Activation of RhoA by lysophosphatidic acid and Gα12/13 subunits in neuronal cells: Induction of neurite retraction
    • Kranenburg O, Poland M, van Horck FP, Drechsel D, Hall A, Moolenaar WH (1999) Activation of RhoA by lysophosphatidic acid and Gα12/13 subunits in neuronal cells: Induction of neurite retraction. Mol Biol Cell 10:1851-1857.
    • (1999) Mol Biol Cell , vol.10 , pp. 1851-1857
    • Kranenburg, O.1    Poland, M.2    Van Horck, F.P.3    Drechsel, D.4    Hall, A.5    Moolenaar, W.H.6
  • 28
    • 0032955426 scopus 로고    scopus 로고
    • Insulin transiently increases tau phosphorylation: Involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase
    • Lesort M, Jope RS, Johnson G V (1999) Insulin transiently increases tau phosphorylation: Involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase. J Neurochem 72:576-584.
    • (1999) J Neurochem , vol.72 , pp. 576-584
    • Lesort, M.1    Jope, R.S.2    Johnson G. V3
  • 30
    • 0031800971 scopus 로고    scopus 로고
    • Inhibition of GSK-3beta leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium
    • Lucas FR, Goold RG, Gordon-Weeks PR, Salinas PC (1998) Inhibition of GSK-3beta leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium. J Cell Sci 111:1351-1361.
    • (1998) J Cell Sci , vol.111 , pp. 1351-1361
    • Lucas, F.R.1    Goold, R.G.2    Gordon-Weeks, P.R.3    Salinas, P.C.4
  • 31
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
    • Lucas JJ, Hernandez F, Gomez-Ramos P, Moran MA, Hen R, Avila J (2001) Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J 20:27-39.
    • (2001) EMBO J , vol.20 , pp. 27-39
    • Lucas, J.J.1    Hernandez, F.2    Gomez-Ramos, P.3    Moran, M.A.4    Hen, R.5    Avila, J.6
  • 33
    • 0032189144 scopus 로고    scopus 로고
    • Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Gα12/13
    • Mao J, Xie W, Yuan H, Simon MI, Mano H, Wu D (1998) Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Gα12/13. EMBO J 17:5638-5646.
    • (1998) EMBO J , vol.17 , pp. 5638-5646
    • Mao, J.1    Xie, W.2    Yuan, H.3    Simon, M.I.4    Mano, H.5    Wu, D.6
  • 34
    • 0033604620 scopus 로고    scopus 로고
    • Bioactive lysophospholipids and their G protein-coupled receptors
    • Moolenaar WH (1999) Bioactive lysophospholipids and their G protein-coupled receptors. Exp Cell Res 253:230-238.
    • (1999) Exp Cell Res , vol.253 , pp. 230-238
    • Moolenaar, W.H.1
  • 35
    • 0032485940 scopus 로고    scopus 로고
    • Gα12 and Gα13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate
    • Needham LK, Rozengurt E (1998) Gα12 and Gα13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate. J Biol Chem 273:14626-14632.
    • (1998) J Biol Chem , vol.273 , pp. 14626-14632
    • Needham, L.K.1    Rozengurt, E.2
  • 37
    • 0027421625 scopus 로고
    • Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments
    • Paudel HK, Lew J, Ali Z, Wang JH (1993) Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments. J Biol Chem 268:23512-23518.
    • (1993) J Biol Chem , vol.268 , pp. 23512-23518
    • Paudel, H.K.1    Lew, J.2    Ali, Z.3    Wang, J.H.4
  • 38
    • 0029879915 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: Action through a specific cell surface receptor
    • Postma FR, Jalink K, Hengeveld T, Moolenaar WH (1996) Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: Action through a specific cell surface receptor. EMBO J 15:2388-2392.
    • (1996) EMBO J , vol.15 , pp. 2388-2392
    • Postma, F.R.1    Jalink, K.2    Hengeveld, T.3    Moolenaar, W.H.4
  • 39
    • 0019025978 scopus 로고
    • Glycogen synthase from rabbit skeletal muscle. Amino acid sequence at the sites phosphorylated by glycogen synthase kinase-3, and extension of the N-terminal sequence containing the site phosphorylated by phosphorylase kinase
    • Rylatt DB, Aitken A, Bilham T, Condon GD, Embi N, Cohen P (1980) Glycogen synthase from rabbit skeletal muscle. Amino acid sequence at the sites phosphorylated by glycogen synthase kinase-3, and extension of the N-terminal sequence containing the site phosphorylated by phosphorylase kinase. Eur J Biochem 107:529-537.
    • (1980) Eur J Biochem , vol.107 , pp. 529-537
    • Rylatt, D.B.1    Aitken, A.2    Bilham, T.3    Condon, G.D.4    Embi, N.5    Cohen, P.6
  • 40
    • 0030796903 scopus 로고    scopus 로고
    • Effects of lysophosphatidic acid on primary cultured chick neurons
    • Saito S (1997) Effects of lysophosphatidic acid on primary cultured chick neurons. Neurosci Lett 229:73-76.
    • (1997) Neurosci Lett , vol.229 , pp. 73-76
    • Saito, S.1
  • 41
    • 0032603742 scopus 로고    scopus 로고
    • Wnt factors in axonal remodelling and synaptogenesis
    • Salinas PC (1999) Wnt factors in axonal remodelling and synaptogenesis. Biochem Soc Symp 65:101-109.
    • (1999) Biochem Soc Symp , vol.65 , pp. 101-109
    • Salinas, P.C.1
  • 42
    • 0033625696 scopus 로고    scopus 로고
    • GSK3beta-mediated phosphorylation of the microtubule-associated protein 2C (MAP2C) prevents microtubule bundling
    • Sanchez C, Perez M, Avila J (2000) GSK3beta-mediated phosphorylation of the microtubule-associated protein 2C (MAP2C) prevents microtubule bundling. Eur J Cell Biol 79:252-260.
    • (2000) Eur J Cell Biol , vol.79 , pp. 252-260
    • Sanchez, C.1    Perez, M.2    Avila, J.3
  • 43
    • 0033601337 scopus 로고    scopus 로고
    • The neurite retraction induced by lysophosphatidic acid increases Alzheimer's disease-like tau phosphorylation
    • Sayas CL, Moreno-Flores MT, Avila J, Wandosell F (1999) The neurite retraction induced by lysophosphatidic acid increases Alzheimer's disease-like tau phosphorylation. J Biol Chem 274:37046-37052.
    • (1999) J Biol Chem , vol.274 , pp. 37046-37052
    • Sayas, C.L.1    Moreno-Flores, M.T.2    Avila, J.3    Wandosell, F.4
  • 44
    • 0034636863 scopus 로고    scopus 로고
    • G13α-mediated PYK2 activation. PYK2 is a mediator of G13α-induced serum response element-dependent transcription
    • Shi CS, Sinnarajah S, Cho H, Kozasa T, Kehrl JH (2000) G13α-mediated PYK2 activation. PYK2 is a mediator of G13α-induced serum response element-dependent transcription. J Biol Chem 275:24470-24476.
    • (2000) J Biol Chem , vol.275 , pp. 24470-24476
    • Shi, C.S.1    Sinnarajah, S.2    Cho, H.3    Kozasa, T.4    Kehrl, J.H.5
  • 45
    • 0030461275 scopus 로고    scopus 로고
    • Regulation of the phosphorylation state and microtubule-binding activity of tau by protein phosphatase 2A
    • Sontag E, Nunbhakdi-Craig V, Lee G, Bloom GS, Mumby MC (1996) Regulation of the phosphorylation state and microtubule-binding activity of tau by protein phosphatase 2A. Neuron 17:1201-1207.
    • (1996) Neuron , vol.17 , pp. 1201-1207
    • Sontag, E.1    Nunbhakdi-Craig, V.2    Lee, G.3    Bloom, G.S.4    Mumby, M.C.5
  • 46
    • 0028981873 scopus 로고
    • Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells
    • Sperber BR, Leight S, Goedert M, Lee VM (1995) Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells. Neurosci Lett 197:149-153.
    • (1995) Neurosci Lett , vol.197 , pp. 149-153
    • Sperber, B.R.1    Leight, S.2    Goedert, M.3    Lee, V.M.4
  • 47
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
    • Stambolic V, Ruel L, Woodgett JR (1996) Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr Biol 6:1664-1668.
    • (1996) Curr Biol , vol.6 , pp. 1664-1668
    • Stambolic, V.1    Ruel, L.2    Woodgett, J.R.3
  • 49
    • 0026519282 scopus 로고
    • Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors
    • Suidan HS, Stone SR, Hemmings BA, Monard D (1992) Thrombin causes neurite retraction in neuronal cells through activation of cell surface receptors. Neuron 8:363-375.
    • (1992) Neuron , vol.8 , pp. 363-375
    • Suidan, H.S.1    Stone, S.R.2    Hemmings, B.A.3    Monard, D.4
  • 50
    • 0028357787 scopus 로고
    • Localization and developmental changes of tau protein kinase I/glycogen synthase kinase-3 beta in rat brain
    • Takahashi M, Tomizawa K, Kato R, Sato K, Uchida T, Fujita SC, Imahori K (1994) Localization and developmental changes of tau protein kinase I/glycogen synthase kinase-3 beta in rat brain. J Neurochem 63:245-255.
    • (1994) J Neurochem , vol.63 , pp. 245-255
    • Takahashi, M.1    Tomizawa, K.2    Kato, R.3    Sato, K.4    Uchida, T.5    Fujita, S.C.6    Imahori, K.7
  • 53
    • 0027430039 scopus 로고
    • Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B
    • Welsh GI, Proud CG (1993) Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B. Biochem J 294:625-629.
    • (1993) Biochem J , vol.294 , pp. 625-629
    • Welsh, G.I.1    Proud, C.G.2
  • 54
    • 0031034809 scopus 로고    scopus 로고
    • Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts
    • Welsh GI, Patel JC, Proud CG (1997) Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts. Anal Biochem 244:16-21.
    • (1997) Anal Biochem , vol.244 , pp. 16-21
    • Welsh, G.I.1    Patel, J.C.2    Proud, C.G.3
  • 55
    • 0033600839 scopus 로고    scopus 로고
    • Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins
    • Windh RT, Lee MJ, Hla T, An S, Barr AJ, Manning DR (1999) Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins. J Biol Chem 274:27351-27358.
    • (1999) J Biol Chem , vol.274 , pp. 27351-27358
    • Windh, R.T.1    Lee, M.J.2    Hla, T.3    An, S.4    Barr, A.J.5    Manning, D.R.6
  • 56
    • 0021796959 scopus 로고
    • Subunit structure of paired helical filaments in Alzheimer's disease
    • Wischik CM, Crowther RA, Stewart M, Roth M (1985) Subunit structure of paired helical filaments in Alzheimer's disease. J Cell Biol 100:1905-1912.
    • (1985) J Cell Biol , vol.100 , pp. 1905-1912
    • Wischik, C.M.1    Crowther, R.A.2    Stewart, M.3    Roth, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.