Caspase-dependent, geldanamycin-enhanced cleavage of co-chaperone p23 in leukemic apoptosis

Leukemia

Volumn 18, Issue 12, 2004, Pages 1989-1996

  Gausdal, G ^a,b   Gjertsen, B T ^b   Fladmark, K E ^a   Demol, H ^c   Vandekerckhove, J ^c   Døkeland, Stein O ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

AML; Anthracyclines; Caspase 7; Co chaperone p23; Geldanamycin

Indexed keywords

ANTHRACYCLINE; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CHAPERONE; CYSTEINE PROTEINASE; CYTARABINE; DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; IDARUBICIN; PROCASPASE 3; PROCASPASE 7; PROTEIN P23; SULFUR 35; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CARCINOGENICITY; CELL SURVIVAL; COMPLEX FORMATION; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; LEUKEMIA; LEUKEMIA CELL LINE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TWO DIMENSIONAL GEL ELECTROPHORESIS;

EID: 11144327054     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403508     Document Type: Article

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