메뉴 건너뛰기




Volumn 54, Issue 6, 2004, Pages 497-504

Chemosensitivity and radiosensitivity profiles of four new human epithelial ovarian cancer cell lines exhibiting genetic alterations in BRCA2, TGFβ-RII, KRAS2, TP53 and/or CDNK2A

Author keywords

Chemosensitivity; Genetic alterations in BRCA2, TGF RII, KRAS2, TP53, and or CDNK2A; Ovarian epithelial cell line; Radiosensitivity

Indexed keywords

BRCA2 PROTEIN; CAMPTOTHECIN; CDNK2A PROTEIN; CISPLATIN; K RAS PROTEIN; PACLITAXEL; PROTEIN; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; UNCLASSIFIED DRUG;

EID: 11144256313     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-004-0843-9     Document Type: Article
Times cited : (43)

References (61)
  • 3
    • 0033055861 scopus 로고    scopus 로고
    • Comparison of mutations of Ki-RAS and p53 immunoreactivity in borderline and malignant epithelial ovarian tumors
    • Caduff RF, Svoboda-Newman SM, Ferguson AW, Johnston CM, Frank TS (1999) Comparison of mutations of Ki-RAS and p53 immunoreactivity in borderline and malignant epithelial ovarian tumors. Am J Surg Pathol 23:323-328
    • (1999) Am J Surg Pathol , vol.23 , pp. 323-328
    • Caduff, R.F.1    Svoboda-Newman, S.M.2    Ferguson, A.W.3    Johnston, C.M.4    Frank, T.S.5
  • 6
    • 0742307268 scopus 로고    scopus 로고
    • In vitro chemoresistance and biomarker profiles are unique for histologic subtypes of epithelial ovarian cancer
    • Cloven NG, Kyshtoobayeva A, Burger RA, Yu IR, Fruehauf JP (2004) In vitro chemoresistance and biomarker profiles are unique for histologic subtypes of epithelial ovarian cancer. Gynecol Oncol 92:160-166
    • (2004) Gynecol Oncol , vol.92 , pp. 160-166
    • Cloven, N.G.1    Kyshtoobayeva, A.2    Burger, R.A.3    Yu, I.R.4    Fruehauf, J.P.5
  • 7
    • 1242273586 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH kinase/AKT and survivin pathways as critical targets for geranylgeranyl-transferase I inhibitor-induced apoptosis
    • Dan HC, Jiang K, Coppola D, Hamilton A, Nicosia SV, Sebti SM, Cheng JQ (2004) Phosphatidylinositol-3-OH kinase/AKT and survivin pathways as critical targets for geranylgeranyl-transferase I inhibitor-induced apoptosis. Oncogene 23:706-715
    • (2004) Oncogene , vol.23 , pp. 706-715
    • Dan, H.C.1    Jiang, K.2    Coppola, D.3    Hamilton, A.4    Nicosia, S.V.5    Sebti, S.M.6    Cheng, J.Q.7
  • 9
    • 0037327473 scopus 로고    scopus 로고
    • K-RAS mutations in ovarian and extraovarian lesions of serous tumors of borderline malignancy
    • Diebold J, Seemuller F, Lohrs U (2003) K-RAS mutations in ovarian and extraovarian lesions of serous tumors of borderline malignancy. Lab Invest 83:251-258
    • (2003) Lab Invest , vol.83 , pp. 251-258
    • Diebold, J.1    Seemuller, F.2    Lohrs, U.3
  • 12
    • 0242610903 scopus 로고    scopus 로고
    • p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells
    • Fraser M, Leung BM, Yan X, Dan HC, Cheng JQ, Tsang BK (2003) p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells. Cancer Res 63:7081-7088
    • (2003) Cancer Res , vol.63 , pp. 7081-7088
    • Fraser, M.1    Leung, B.M.2    Yan, X.3    Dan, H.C.4    Cheng, J.Q.5    Tsang, B.K.6
  • 13
    • 0038627539 scopus 로고    scopus 로고
    • Genetic alterations in ovarian carcinoma: With specific reference to histological subtypes
    • Fujita M, Enomoto T, Murata Y (2003) Genetic alterations in ovarian carcinoma: with specific reference to histological subtypes. Mol Cell Endocrinol 202:97-99
    • (2003) Mol Cell Endocrinol , vol.202 , pp. 97-99
    • Fujita, M.1    Enomoto, T.2    Murata, Y.3
  • 15
    • 0032479412 scopus 로고    scopus 로고
    • Ras mutation and platinum resistance in human ovarian carcinomas in vitro
    • Holford J, Rogers P, Kelland LR (1998) Ras mutation and platinum resistance in human ovarian carcinomas in vitro. Int J Cancer 77:94-100
    • (1998) Int J Cancer , vol.77 , pp. 94-100
    • Holford, J.1    Rogers, P.2    Kelland, L.R.3
  • 16
    • 0037365636 scopus 로고    scopus 로고
    • Murine models of colorectal cancer: Studying the role of oncogenic K-ras
    • Janssen KP (2003) Murine models of colorectal cancer: studying the role of oncogenic K-ras. Cell Mol Life Sci 60:495-506
    • (2003) Cell Mol Life Sci , vol.60 , pp. 495-506
    • Janssen, K.P.1
  • 17
    • 0036953625 scopus 로고    scopus 로고
    • Wnt/beta-catenin/tcf signaling: A critical pathway in gastrointestinal tumorigenesis
    • Kolligs FT, Bommer G, Goke B (2002) Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis. Digestion 66:131-144
    • (2002) Digestion , vol.66 , pp. 131-144
    • Kolligs, F.T.1    Bommer, G.2    Goke, B.3
  • 18
    • 0025322319 scopus 로고
    • A simplified method to culture human ovarian surface epithelium
    • Kruk PA, Maines-Bandiera SL, Auersperg N (1990) A simplified method to culture human ovarian surface epithelium. Lab Invest 63:132-136
    • (1990) Lab Invest , vol.63 , pp. 132-136
    • Kruk, P.A.1    Maines-Bandiera, S.L.2    Auersperg, N.3
  • 20
    • 0034331289 scopus 로고    scopus 로고
    • A frequent deletion polymorphism on chromosome 22q13 identified by representational difference analysis of ovarian cancer
    • Lin H, Pizer ES, Morin PJ (2000) A frequent deletion polymorphism on chromosome 22q13 identified by representational difference analysis of ovarian cancer. Genomics 69:391-394
    • (2000) Genomics , vol.69 , pp. 391-394
    • Lin, H.1    Pizer, E.S.2    Morin, P.J.3
  • 21
    • 0028116927 scopus 로고
    • Primary cultures of normal and tumoral human ovarian epithelium: A powerful tool for basic molecular studies
    • Lounis H, Provencher D, Godbout C, Fink D, Milot MJ, Mes-Masson AM (1994) Primary cultures of normal and tumoral human ovarian epithelium: a powerful tool for basic molecular studies. Exp Cell Res 215:303-309
    • (1994) Exp Cell Res , vol.215 , pp. 303-309
    • Lounis, H.1    Provencher, D.2    Godbout, C.3    Fink, D.4    Milot, M.J.5    Mes-Masson, A.M.6
  • 23
    • 0034002962 scopus 로고    scopus 로고
    • Mutations in a 10-bp polyadenine repeat of transforming growth factor beta-receptor type II gene is an infrequent event in human epithelial ovarian cancer
    • Manderson EN, Mes-Masson AM, Provencher D, Tonin PN (2000) Mutations in a 10-bp polyadenine repeat of transforming growth factor beta-receptor type II gene is an infrequent event in human epithelial ovarian cancer. Clin Genet 57:151-153
    • (2000) Clin Genet , vol.57 , pp. 151-153
    • Manderson, E.N.1    Mes-Masson, A.M.2    Provencher, D.3    Tonin, P.N.4
  • 25
    • 0034039215 scopus 로고    scopus 로고
    • Emergence of cisplatin-resistant cells from the OVCAR-3 ovarian carcinoma cell line with p53 mutations, altered tumorigenicity, and increased apoptotic sensitivity to p53 gene replacement
    • Mujoo K, Zhang L, Klostergaard J, Donate NJ (2000) Emergence of cisplatin-resistant cells from the OVCAR-3 ovarian carcinoma cell line with p53 mutations, altered tumorigenicity, and increased apoptotic sensitivity to p53 gene replacement. Int J Gynecol Cancer 10:105-114
    • (2000) Int J Gynecol Cancer , vol.10 , pp. 105-114
    • Mujoo, K.1    Zhang, L.2    Klostergaard, J.3    Donate, N.J.4
  • 26
    • 0035254941 scopus 로고    scopus 로고
    • Loss of heterozygosity at 7q22 and mutation analysis of the CDP gene in human epithelial ovarian tumors
    • Neville PJ, Thomas N, Campbell IG (2001) Loss of heterozygosity at 7q22 and mutation analysis of the CDP gene in human epithelial ovarian tumors. Int J Cancer 91:345-349
    • (2001) Int J Cancer , vol.91 , pp. 345-349
    • Neville, P.J.1    Thomas, N.2    Campbell, I.G.3
  • 28
    • 0033659110 scopus 로고    scopus 로고
    • Common genetic changes between endometriosis and ovarian cancer
    • Obata K, Hoshiai H (2000) Common genetic changes between endometriosis and ovarian cancer. Gynecol Obstet Invest 50:39-43
    • (2000) Gynecol Obstet Invest , vol.50 , pp. 39-43
    • Obata, K.1    Hoshiai, H.2
  • 30
    • 1542509662 scopus 로고    scopus 로고
    • FANCF methylation contributes to chemoselectivity in ovarian cancer
    • Olopade OI, Wei M (2003) FANCF methylation contributes to chemoselectivity in ovarian cancer. Cancer Cell 3:417-420
    • (2003) Cancer Cell , vol.3 , pp. 417-420
    • Olopade, O.I.1    Wei, M.2
  • 31
    • 0036583718 scopus 로고    scopus 로고
    • Update on the management of ovarian cancer
    • Ozols RF (2002) Update on the management of ovarian cancer. Cancer J 8(Suppl 1):S22-S30
    • (2002) Cancer J , vol.8 , Issue.1 SUPPL.
    • Ozols, R.F.1
  • 39
    • 0036581755 scopus 로고    scopus 로고
    • Linking DNA damage to cell cycle checkpoints
    • Samuel T, Weber HO, Funk JO (2002) Linking DNA damage to cell cycle checkpoints. Cell Cycle 1:162-168
    • (2002) Cell Cycle , vol.1 , pp. 162-168
    • Samuel, T.1    Weber, H.O.2    Funk, J.O.3
  • 40
    • 0034469155 scopus 로고    scopus 로고
    • Role of BRCA gene dysfunction in breast and ovarian cancer predisposition
    • Scully R (2000) Role of BRCA gene dysfunction in breast and ovarian cancer predisposition. Breast Cancer Res 2:324-330
    • (2000) Breast Cancer Res , vol.2 , pp. 324-330
    • Scully, R.1
  • 41
    • 0035835821 scopus 로고    scopus 로고
    • Interactions between BRCA proteins and DNA structure
    • Scully R (2001) Interactions between BRCA proteins and DNA structure. Exp Cell Res 264:67-73
    • (2001) Exp Cell Res , vol.264 , pp. 67-73
    • Scully, R.1
  • 45
    • 0037216291 scopus 로고    scopus 로고
    • Mutational analysis of K-ras segregates ovarian serous carcinomas into two types: Invasive MPSC (low-grade tumor) and conventional serous carcinoma (high-grade tumor)
    • Singer G, Shih Ie M, Truskinovsky A, Umudum H, Kurman RJ (2003) Mutational analysis of K-ras segregates ovarian serous carcinomas into two types: invasive MPSC (low-grade tumor) and conventional serous carcinoma (high-grade tumor). Int J Gynecol Pathol 22:37-41
    • (2003) Int J Gynecol Pathol , vol.22 , pp. 37-41
    • Singer, G.1    Shih Ie, M.2    Truskinovsky, A.3    Umudum, H.4    Kurman, R.J.5
  • 47
    • 0034213974 scopus 로고    scopus 로고
    • Clinical characteristics of clear cell carcinoma of the ovary: A distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy
    • Sugiyama T, Kamura T, Kigawa J, Terakawa N, Kikuchi Y, Kita T, Suzuki M, Sato I, Taguchi K (2000) Clinical characteristics of clear cell carcinoma of the ovary: a distinct histologic type with poor prognosis and resistance to platinum-based chemotherapy. Cancer 88:2584-2589
    • (2000) Cancer , vol.88 , pp. 2584-2589
    • Sugiyama, T.1    Kamura, T.2    Kigawa, J.3    Terakawa, N.4    Kikuchi, Y.5    Kita, T.6    Suzuki, M.7    Sato, I.8    Taguchi, K.9
  • 48
    • 0034655882 scopus 로고    scopus 로고
    • Mutation of K-RAS protooncogene and loss of heterozygosity on 6q27 in serous and mucinous ovarian carcinomas
    • Suzuki M, Saito S, Saga Y, Ohwada M, Sato I (2000) Mutation of K-RAS protooncogene and loss of heterozygosity on 6q27 in serous and mucinous ovarian carcinomas. Cancer Genet Cytogenet 118:132-135
    • (2000) Cancer Genet Cytogenet , vol.118 , pp. 132-135
    • Suzuki, M.1    Saito, S.2    Saga, Y.3    Ohwada, M.4    Sato, I.5
  • 50
    • 0036592738 scopus 로고    scopus 로고
    • Radiation therapy for gynecologic cancer
    • Tewari KS, DiSaia PJ (2002) Radiation therapy for gynecologic cancer. J Obstet Gynaecol Res 28:123-140
    • (2002) J Obstet Gynaecol Res , vol.28 , pp. 123-140
    • Tewari, K.S.1    DiSaia, P.J.2
  • 54
    • 0030465009 scopus 로고    scopus 로고
    • Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance
    • Vasey PA, Jones NA, Jenkins S, Dive C, Brown R (1996) Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance. Mol Pharmacol 50:1536-1540
    • (1996) Mol Pharmacol , vol.50 , pp. 1536-1540
    • Vasey, P.A.1    Jones, N.A.2    Jenkins, S.3    Dive, C.4    Brown, R.5
  • 55
    • 0037169354 scopus 로고    scopus 로고
    • Cancer susceptibility and the functions of BRCA1 and BRCA2
    • Venkitaraman AR (2002) Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 108:171-182
    • (2002) Cell , vol.108 , pp. 171-182
    • Venkitaraman, A.R.1
  • 58
    • 0034946638 scopus 로고    scopus 로고
    • Genetic interactions between tumor suppressors Brcal and p53 in apoptosis, cell cycle and tumorigenesis
    • Xu X, Qiao W, Linke SP, Cao L, Li WM, Furth PA, Harris CC, Deng CX (2001) Genetic interactions between tumor suppressors Brcal and p53 in apoptosis, cell cycle and tumorigenesis. Nat Genet 28:266-271
    • (2001) Nat Genet , vol.28 , pp. 266-271
    • Xu, X.1    Qiao, W.2    Linke, S.P.3    Cao, L.4    Li, W.M.5    Furth, P.A.6    Harris, C.C.7    Deng, C.X.8
  • 61
    • 0037099520 scopus 로고    scopus 로고
    • Deficient nonhomologous end-joining activity in cell-free extracts from Brcal-null fibroblasts
    • Zhong Q, Boyer TG, Chen PL, Lee WH (2002) Deficient nonhomologous end-joining activity in cell-free extracts from Brcal-null fibroblasts. Cancer Res 62:3966-3970
    • (2002) Cancer Res , vol.62 , pp. 3966-3970
    • Zhong, Q.1    Boyer, T.G.2    Chen, P.L.3    Lee, W.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.